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Showing 401 - 420 of 1970 results

Lessons Learned in Establishing and Sustaining Elastomeric Half Mask Respirator-based Respiratory Protection Programs: an Impact Evaluation.

Haas, Emily J. ;

Edirisooriya, Mihili

March 2025 | Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 3

Developing and overseeing Respiratory Protection Programs (RPPs) is crucial for ensuring effective respirator use among employees. To date, a gap exists in research that focuses on elastomeric half mask respirators (EHMRs) as the primary respirator in health delivery settings which would necessitate additional considerations in RPPs beyond the more ...

10/09/2026

Supporting Files

Title : Lessons Learned in Establishing and Sustaining Elastomeric Half Mask Respirator-based Respiratory Protection Programs: an Impact Evaluation. Personal Author(s) : Haas, Emily J.;Edirisooriya, Mihili; Published Date : March 2025 Pages in Document : 178-188 (19 pdf pages) Source : Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 3 DOI : https://doi.org/10.1080/15459624.2024.2431227 Journal Title : Journal of Occupational and Environmental Hygiene
Haas, E. J., & Edirisooriya, M. (2025). Lessons Learned in Establishing and Sustaining Elastomeric Half Mask Respirator-based Respiratory Protection Programs: an Impact Evaluation. Journal of Occupational and Environmental Hygiene, 22(3). https://doi.org/10.1080/15459624.2024.2431227

Haas, Emily J. and Mihili Edirisooriya. "Lessons Learned in Establishing and Sustaining Elastomeric Half Mask Respirator-based Respiratory Protection Programs: an Impact Evaluation." Journal of Occupational and Environmental Hygiene 22, no. 3 (2025). https://doi.org/10.1080/15459624.2024.2431227.

Haas, Emily J., and Mihili Edirisooriya "Lessons Learned in Establishing and Sustaining Elastomeric Half Mask Respirator-based Respiratory Protection Programs: an Impact Evaluation." Journal of Occupational and Environmental Hygiene, vol. 22, no. 3, 2025. Stacks. https://doi.org/10.1080/15459624.2024.2431227.
Export RIS Citation Information. TY - Journal Article AU - Haas, Emily J. AU - Edirisooriya, Mihili AB - Developing and overseeing Respiratory Protection Programs (RPPs) is crucial for ensuring effective respirator use among employees. To date, a gap exists in research that focuses on elastomeric half mask respirators (EHMRs) as the primary respirator in health delivery settings which would necessitate additional considerations in RPPs beyond the more common N95 filtering facepiece respirators. This paper presents lessons learned during a one-year impact evaluation with healthcare and first responder settings that received EHMRs from the Strategic National Stockpile in 2021 and 2022. The study explored the advantages and disadvantages associated with EHMRs and the challenges related to establishing, implementing, maintaining, and sustaining EHMR-based RPPs. Data was received from 42 organizations that participated in EHMR demonstration projects to address (1) the most important, perceived, elements and practices of an EHMR-based RPP to support a long-term program; and (2) differences in perceptions of the most important elements and practices based on organizational and company size (i.e., small, medium, and large). Sustaining an EHMR program was considered the most important area to focus future efforts ( AB - = 2.94; SD = 1.12 on a 4-point scale), followed by daily maintenance of the program ( AB - = 2.72; SD = 0.974), development and implementation of the program ( AB - = 2.42; SD = 1.05), and access to EHMRs ( AB - = 1.91; SD = 1.11), respectively. Findings also revealed statistically significant differences in perceptions based on organization size, particularly in access to EHMR models/designs. Results underscored the significance of user accountability, organizational support, and culture in EHMR-based RPPs to support emergency preparedness efforts. AB - Author manuscript AN - cdc:261866 C4 - PMC11938045 DO - https://doi.org/10.1080/15459624.2024.2431227 IS - 3 J2 - Journal of Occupational and Environmental Hygiene KW - Occupational Exposure KW - N95 Respirators KW - Masks KW - Equipment Design KW - Respiratory Protective Devices KW - Elastomers KW - Humans KW - Program Evaluation KW - COVID-19 KW - Demonstration project KW - health delivery settings KW - longitudinal evaluation KW - organizational support KW - sustainability KW - Humans KW - Respiratory Protective Devices KW - Masks KW - Occupational Exposure KW - Elastomers KW - COVID-19 KW - Equipment Design KW - Program Evaluation KW - N95 Respirators LA - eng PY - 2025 T2 - Journal of Occupational and Environmental Hygiene T2 - Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 3 TI - Lessons Learned in Establishing and Sustaining Elastomeric Half Mask Respirator-based Respiratory Protection Programs: an Impact Evaluation. VL - 22 UR - https://stacks.cdc.gov/view/cdc/261866 ER -
Influenza Vaccine Effectiveness Against Hospitalizations and Emergency Department or Urgent Care Encounters For Children, Adolescents, and Adults During the 2023-2024 Season, United States.

Tenforde, Mark W. ;

Reeves, Emily L.

October 2025 | Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 81, no. 3

The 2023-2024 influenza season had predominant influenza A(H1N1)pdm09 virus activity, but A(H3N2) and B viruses cocirculated. Seasonal influenza vaccine strains were well-matched to these viruses.Using healthcare encounters data from health systems in 8 US states, we evaluated influenza vaccine effectiveness (VE) against influenza-associated medica ...

10/09/2026

Supporting Files

Title : Influenza Vaccine Effectiveness Against Hospitalizations and Emergency Department or Urgent Care Encounters For Children, Adolescents, and Adults During the 2023-2024 Season, United States. Personal Author(s) : Tenforde, Mark W.;Reeves, Emily L.;Weber, Zachary A.;Tartof, Sara Y.;Klein, Nicola P.;Dascomb, Kristin;DeSilva, Malini B.;Yang, Duck-Hye;Grannis, Shaun J.;Irving, Stephanie A.;Ong, Toan C.;Link-Gelles, Ruth;Salas, S. Bianca;Sy, Lina S.;Lewin, Bruno;Contreras, Richard;Zerbo, Ousseny;Fireman, Bruce;Hansen, John;Timbol, Julius;Sheffield, Tamara;Bride, Daniel;Arndorfer, Julie;VanOtterloo, Josh;McEvoy, Charlene E.;Akinsete, Omobosola O.;Essien, Inih J.;Dixon, Brian E.;Rogerson, Colin;Fadel, William F.;Duszynski, Thomas;Naleway, Allison L.;Barron, Michelle A.;Rao, Suchitra;Mayer, David;Chavez, Catia;Ball, Sarah W.;Payne, Amanda B.;Ray, Caitlin;Dickerson, Monica;Neelam, Varsha;Adams, Katherine;Flannery, Brendan;DeCuir, Jennifer;Garg, Shikha; Published Date : October 2025 Pages in Document : 667-678 (24 pdf pages) Source : Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 81, no. 3 DOI : https://doi.org/10.1093/cid/ciae597 Journal Title : Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Tenforde, M. W., Reeves, E. L., Weber, Z. A., Tartof, S. Y., Klein, N. P., Dascomb, K., DeSilva, M. B., Yang, D. H., Grannis, S. J., Irving, S. A., Ong, T. C., Link-Gelles, R., Salas, S. B., Sy, L. S., Lewin, B., Contreras, R., Zerbo, O., Fireman, B., Hansen, J., ... Garg, S. (2025). Influenza Vaccine Effectiveness Against Hospitalizations and Emergency Department or Urgent Care Encounters For Children, Adolescents, and Adults During the 2023-2024 Season, United States. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 81(3). https://doi.org/10.1093/cid/ciae597

Tenforde, Mark W., Emily L. Reeves, Zachary A. Weber, Sara Y. Tartof, Nicola P. Klein, Kristin Dascomb, and Malini B. DeSilva, et al.. "Influenza Vaccine Effectiveness Against Hospitalizations and Emergency Department or Urgent Care Encounters For Children, Adolescents, and Adults During the 2023-2024 Season, United States." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 81, no. 3 (2025). https://doi.org/10.1093/cid/ciae597.

Tenforde, Mark W., et al. "Influenza Vaccine Effectiveness Against Hospitalizations and Emergency Department or Urgent Care Encounters For Children, Adolescents, and Adults During the 2023-2024 Season, United States." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, vol. 81, no. 3, 2025. Stacks. https://doi.org/10.1093/cid/ciae597.
Export RIS Citation Information. TY - Journal Article AU - Tenforde, Mark W. AU - Reeves, Emily L. AU - Weber, Zachary A. AU - Tartof, Sara Y. AU - Klein, Nicola P. AU - Dascomb, Kristin AU - DeSilva, Malini B. AU - Yang, Duck-Hye AU - Grannis, Shaun J. AU - Irving, Stephanie A. AU - Ong, Toan C. AU - Link-Gelles, Ruth AU - Salas, S. Bianca AU - Sy, Lina S. AU - Lewin, Bruno AU - Contreras, Richard AU - Zerbo, Ousseny AU - Fireman, Bruce AU - Hansen, John AU - Timbol, Julius AU - Sheffield, Tamara AU - Bride, Daniel AU - Arndorfer, Julie AU - VanOtterloo, Josh AU - McEvoy, Charlene E. AU - Akinsete, Omobosola O. AU - Essien, Inih J. AU - Dixon, Brian E. AU - Rogerson, Colin AU - Fadel, William F. AU - Duszynski, Thomas AU - Naleway, Allison L. AU - Barron, Michelle A. AU - Rao, Suchitra AU - Mayer, David AU - Chavez, Catia AU - Ball, Sarah W. AU - Payne, Amanda B. AU - Ray, Caitlin AU - Dickerson, Monica AU - Neelam, Varsha AU - Adams, Katherine AU - Flannery, Brendan AU - DeCuir, Jennifer AU - Garg, Shikha AB - The 2023-2024 influenza season had predominant influenza A(H1N1)pdm09 virus activity, but A(H3N2) and B viruses cocirculated. Seasonal influenza vaccine strains were well-matched to these viruses. AB - Using healthcare encounters data from health systems in 8 US states, we evaluated influenza vaccine effectiveness (VE) against influenza-associated medical encounters from October 2023 to April 2024. Using a test-negative design, we compared the odds of vaccination between patients with an acute respiratory illness who tested positive (cases) versus negative (controls) for influenza by molecular assay, adjusting for confounders. VE was stratified by age group, influenza type (overall, influenza A, influenza B), and care setting (hospitalization, emergency department or urgent care [ED/UC] encounter). AB - Overall, 74 000 encounters in children and adolescents aged 6 months-17 years (3479 hospitalizations, 70 521 ED/UC encounters) and 267 606 in adults aged ≥18 years (66 828 hospitalizations, 200 778 ED/UC encounters) were included. Across care settings, among children and adolescents, 15% (2758/17 833) of cases versus 32% (18 240/56 167) of controls had received vaccination. Among adults, 25% (11 632/46 614) of cases versus 44% (97 811/220 992) of controls across care settings had received vaccination. VE was 58% (95% confidence interval [95% CI], 44-69) against hospitalization and 58% (95% CI, 56-60) against ED/UC encounters for children and adolescents, and 39% (95% CI, 35-43) against hospitalization and 47% (95% CI, 46-49) against ED/UC encounters for adults. Across age groups, VE was higher against influenza B than influenza A. AB - Influenza vaccines provided protection against influenza-associated illness across health care settings and age groups during the 2023-2024 influenza season. AB - Author manuscript AN - cdc:261865 C4 - PMC12287760 DO - https://doi.org/10.1093/cid/ciae597 IS - 3 J2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America KW - Adolescent KW - Female KW - Influenza B virus KW - Influenza A Virus, H1N1 Subtype KW - Vaccination KW - Aged KW - Young Adult KW - Emergency Service, Hospital KW - Influenza Vaccines KW - Child KW - Ambulatory Care KW - Infant KW - Vaccine Efficacy KW - Hospitalization KW - Seasons KW - Male KW - Influenza A Virus, H3N2 Subtype KW - Humans KW - Middle Aged KW - Child, Preschool KW - Adult KW - Influenza, Human KW - influenza KW - vaccine effectiveness KW - vaccination KW - test-negative design KW - Humans KW - Adolescent KW - Influenza, Human KW - Child KW - Influenza Vaccines KW - Hospitalization KW - Adult KW - Child, Preschool KW - Emergency Service, Hospital KW - Male KW - Infant KW - Female KW - Young Adult KW - Vaccine Efficacy KW - Middle Aged KW - Aged KW - Ambulatory Care KW - Influenza A Virus, H3N2 Subtype KW - Influenza A Virus, H1N1 Subtype KW - Seasons KW - Vaccination KW - Influenza B virus LA - eng PY - 2025 T2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America T2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 81, no. 3 TI - Influenza Vaccine Effectiveness Against Hospitalizations and Emergency Department or Urgent Care Encounters For Children, Adolescents, and Adults During the 2023-2024 Season, United States. VL - 81 UR - https://stacks.cdc.gov/view/cdc/261865 ER -
Acetabular Dysplasia and the Risk of Developing Hip Osteoarthritis Within 4-8 Years: an Individual Participant Data Meta-analysis of 18,807 Hips From the World COACH Consortium.

Riedstra, Noortje S. ;

Boel, Fleur

March 2025 | Osteoarthritis and Cartilage, 2025, v. 33, no. 3

To study the association between various radiographic definitions of acetabular dysplasia (AD) and incident radiographic hip osteoarthritis (RHOA), and to analyze in subgroups.Hips free of RHOA at baseline and with follow-up within 4-8 years were drawn from the World COACH consortium. The Wiberg center edge angle (WCEA), acetabular depth width rati ...

10/09/2026

Supporting Files

Title : Acetabular Dysplasia and the Risk of Developing Hip Osteoarthritis Within 4-8 Years: an Individual Participant Data Meta-analysis of 18,807 Hips From the World COACH Consortium. Personal Author(s) : Riedstra, Noortje S.;Boel, Fleur;van Buuren, Michiel M.A.;Ahedi, Harbeer;Arbabi, Vahid;Arden, Nigel;Baart, Sara J.;Bierma-Zeinstra, Sita M.A.;Cicuttini, Flavia M.;Cootes, Timothy F.;Crossley, Kay M.;Felson, David T.;Giellis, Willem Paul;Heerey, Joshua;Jones, Graeme;Kluzek, Stefan;Lane, Nancy E.;Lindner, Claudia;Lynch, John A.;van Meurs, Joyce B.J.;Mosler, Andrea;Nelson, Amanda E.;Nevitt, Michael C.;Oei, Edwin H.;Runhaar, Jos;Tang, Jinchi;Weinans, Harrie;Agricola, Rintje; Published Date : March 2025 Pages in Document : 373-382 (21 pdf pages) Source : Osteoarthritis and Cartilage, 2025, v. 33, no. 3 DOI : https://doi.org/10.1016/j.joca.2024.12.001 Journal Title : Osteoarthritis and Cartilage
Riedstra, N. S., Boel, F., van Buuren, M. M., Ahedi, H., Arbabi, V., Arden, N., Baart, S. J., Bierma-Zeinstra, S. M., Cicuttini, F. M., Cootes, T. F., Crossley, K. M., Felson, D. T., Giellis, W. P., Heerey, J., Jones, G., Kluzek, S., Lane, N. E., Lindner, C., Lynch, J. A., ... Agricola, R. (2025). Acetabular Dysplasia and the Risk of Developing Hip Osteoarthritis Within 4-8 Years: an Individual Participant Data Meta-analysis of 18,807 Hips From the World COACH Consortium. Osteoarthritis and Cartilage, 33(3). https://doi.org/10.1016/j.joca.2024.12.001

Riedstra, Noortje S., Fleur Boel, Michiel M.A. van Buuren, Harbeer Ahedi, Vahid Arbabi, Nigel Arden, and Sara J. Baart, et al.. "Acetabular Dysplasia and the Risk of Developing Hip Osteoarthritis Within 4-8 Years: an Individual Participant Data Meta-analysis of 18,807 Hips From the World COACH Consortium." Osteoarthritis and Cartilage 33, no. 3 (2025). https://doi.org/10.1016/j.joca.2024.12.001.

Riedstra, Noortje S., et al. "Acetabular Dysplasia and the Risk of Developing Hip Osteoarthritis Within 4-8 Years: an Individual Participant Data Meta-analysis of 18,807 Hips From the World COACH Consortium." Osteoarthritis and Cartilage, vol. 33, no. 3, 2025. Stacks. https://doi.org/10.1016/j.joca.2024.12.001.
Export RIS Citation Information. TY - Journal Article AU - Riedstra, Noortje S. AU - Boel, Fleur AU - van Buuren, Michiel M.A. AU - Ahedi, Harbeer AU - Arbabi, Vahid AU - Arden, Nigel AU - Baart, Sara J. AU - Bierma-Zeinstra, Sita M.A. AU - Cicuttini, Flavia M. AU - Cootes, Timothy F. AU - Crossley, Kay M. AU - Felson, David T. AU - Giellis, Willem Paul AU - Heerey, Joshua AU - Jones, Graeme AU - Kluzek, Stefan AU - Lane, Nancy E. AU - Lindner, Claudia AU - Lynch, John A. AU - van Meurs, Joyce B.J. AU - Mosler, Andrea AU - Nelson, Amanda E. AU - Nevitt, Michael C. AU - Oei, Edwin H. AU - Runhaar, Jos AU - Tang, Jinchi AU - Weinans, Harrie AU - Agricola, Rintje AB - To study the association between various radiographic definitions of acetabular dysplasia (AD) and incident radiographic hip osteoarthritis (RHOA), and to analyze in subgroups. AB - Hips free of RHOA at baseline and with follow-up within 4-8 years were drawn from the World COACH consortium. The Wiberg center edge angle (WCEA), acetabular depth width ratio (ADR), and the modified acetabular index (mAI) were calculated. AD was defined as WCEA≤25°, and for secondary analyses as WCEA≤20°, ADR ≤250, mAI ≥ 13°, and a combination. A logistic regression model with generalized mixed effects with 3 levels adjusted for age, biological sex, and body mass index (BMI) was used. Descriptive statistics stratified by age, biological sex and BMI were reported. AB - A total of 18,807 hips from 9 studies were included. Baseline characteristics: age 61.84 (± 8.32) years, BMI 27.40 (± 4.49) kg/m², 70.1% women. 4766 hips (25.3%) had WCEA≤25°. Within 4-8 years (mean 5.8 ±1.6) follow-up, 378 hips (2.0%) developed incident RHOA. We found an association between AD and RHOA (adjusted OR [aOR] 1.80 95% confidence interval [CI] 1.40-2.34). In secondary analyses, all other definitions of AD were also associated with incident RHOA (aOR ranging from 1.52 95% CI 1.19-1.94 to 1.96 95% CI 1.26-3.02). Descriptive statistics showed that the relative risk (RR) in AD hips to develop RHOA was higher compared to non-AD hips in age group 61-70 (RR 1.70), BMI<25 (RR 1.66), and in female hips (RR 1.73). AB - AD was consistently associated with incident RHOA. Explorative analyses show that AD hips in women and age group 61-70 years seem to be more at risk of developing RHOA compared to non-AD hips. AB - Author manuscript AN - cdc:261864 C4 - PMC12239852 DO - https://doi.org/10.1016/j.joca.2024.12.001 IS - 3 J2 - Osteoarthritis and Cartilage KW - Acetabulum KW - Female KW - Risk Factors KW - Radiography KW - Osteoarthritis, Hip KW - Aged KW - Male KW - Middle Aged KW - Humans KW - Developmental Dysplasia of the Hip KW - Hip imaging KW - Risk factor KW - Developmental dysplasia KW - Harmonized KW - Epidemiology KW - Humans KW - Osteoarthritis, Hip KW - Female KW - Middle Aged KW - Male KW - Acetabulum KW - Aged KW - Radiography KW - Risk Factors KW - Developmental Dysplasia of the Hip LA - eng PY - 2025 T2 - Osteoarthritis and Cartilage T2 - Osteoarthritis and Cartilage, 2025, v. 33, no. 3 TI - Acetabular Dysplasia and the Risk of Developing Hip Osteoarthritis Within 4-8 Years: an Individual Participant Data Meta-analysis of 18,807 Hips From the World COACH Consortium. VL - 33 UR - https://stacks.cdc.gov/view/cdc/261864 ER -
The Role of Human Papillomavirus 16 In Oral Cavity and Laryngeal Cancers in the United States.

Kava, Christine M. ;

Chaturvedi, Anil K.

July 2025 | Journal of the National Cancer Institute, 2025, v. 117, no. 7

In addition to oropharyngeal cancers, evidence suggests that there may be an etiologic role for human papillomavirus (HPV) in some other head and neck cancers arising from the oral cavity and larynx. We estimated the burden of HPV16-attributable cancers of the oral cavity (International Classification of Diseases for Oncology, 3rd Edition, site cod ...

10/09/2026

Supporting Files

Title : The Role of Human Papillomavirus 16 In Oral Cavity and Laryngeal Cancers in the United States. Personal Author(s) : Kava, Christine M.;Chaturvedi, Anil K.;Senkomago, Virginia;Mix, Jacqueline M.;Markowitz, Lauri E.;Kreimer, Aimée R.;Unger, Elizabeth R.;Saraiya, Mona; Published Date : July 2025 Pages in Document : 1492-1497 (10 pdf pages) Source : Journal of the National Cancer Institute, 2025, v. 117, no. 7 DOI : https://doi.org/10.1093/jnci/djae320 Journal Title : Journal of the National Cancer Institute
Kava, C. M., Chaturvedi, A. K., Senkomago, V., Mix, J. M., Markowitz, L. E., Kreimer, A. R., Unger, E. R., & Saraiya, M. (2025). The Role of Human Papillomavirus 16 In Oral Cavity and Laryngeal Cancers in the United States. Journal of the National Cancer Institute, 117(7). https://doi.org/10.1093/jnci/djae320

Kava, Christine M., Anil K. Chaturvedi, Virginia Senkomago, Jacqueline M. Mix, Lauri E. Markowitz, Aimée R. Kreimer, Elizabeth R. Unger, and Mona Saraiya. "The Role of Human Papillomavirus 16 In Oral Cavity and Laryngeal Cancers in the United States." Journal of the National Cancer Institute 117, no. 7 (2025). https://doi.org/10.1093/jnci/djae320.

Kava, Christine M., et al. "The Role of Human Papillomavirus 16 In Oral Cavity and Laryngeal Cancers in the United States." Journal of the National Cancer Institute, vol. 117, no. 7, 2025. Stacks. https://doi.org/10.1093/jnci/djae320.
Export RIS Citation Information. TY - Journal Article AU - Kava, Christine M. AU - Chaturvedi, Anil K. AU - Senkomago, Virginia AU - Mix, Jacqueline M. AU - Markowitz, Lauri E. AU - Kreimer, Aimée R. AU - Unger, Elizabeth R. AU - Saraiya, Mona AB - In addition to oropharyngeal cancers, evidence suggests that there may be an etiologic role for human papillomavirus (HPV) in some other head and neck cancers arising from the oral cavity and larynx. We estimated the burden of HPV16-attributable cancers of the oral cavity (International Classification of Diseases for Oncology, 3rd Edition, site codes C02.0-C02.3, C02.9, C03.0, C03.1, C03.9, C04.0, C04.1, C04.8, C04.9, C05.0, C05.8, C05.9, C06.0-C06.2, C06.8, C06.9) and larynx (C32.0-C32.3, C32.8, C32.9) in the United States by pooling estimates from published case studies to calculate HPV16-attributable fractions and applying the HPV16-attributable fractions to 2016-2020 US Cancer Statistics data. During 2016-2020, of an average annual number of 12 612 oral cavity cancers, 3.9% (n = 497) were estimated to be attributable to HPV16. Of an average annual number of 11 170 laryngeal cancers, 2.8% (n = 309) were estimated to be attributable to HPV16. This information can improve surveillance of HPV16-attributable cancers in the US population and inform our understanding of the potential impact of HPV vaccination on cancers of the oral cavity and larynx. AB - Author manuscript AN - cdc:261863 C4 - PMC12146420 DO - https://doi.org/10.1093/jnci/djae320 IS - 7 J2 - Journal of the National Cancer Institute KW - Female KW - Papillomavirus Infections KW - Laryngeal Neoplasms KW - Mouth Neoplasms KW - Male KW - Middle Aged KW - Humans KW - Human papillomavirus 16 KW - Humans KW - Mouth Neoplasms KW - Human papillomavirus 16 KW - Papillomavirus Infections KW - Laryngeal Neoplasms KW - Female KW - Male KW - Middle Aged LA - eng PY - 2025 T2 - Journal of the National Cancer Institute T2 - Journal of the National Cancer Institute, 2025, v. 117, no. 7 TI - The Role of Human Papillomavirus 16 In Oral Cavity and Laryngeal Cancers in the United States. VL - 117 UR - https://stacks.cdc.gov/view/cdc/261863 ER -
Associations of Maternal Peripregnancy Cannabis Use With Behavioral and Developmental Outcomes in Children With and Without Symptoms of Autism Spectrum Disorder: Study to Explore Early Development.

DiGuiseppi, Carolyn ;

Crume, Tessa

January 2025 | Autism Research : Official Journal of the International Society for Autism Research, 2025, v. 18, no. 1

Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3 months preconception through delivery ("peripregnancy") with behavior and development in the offspring varied with the presence of ASD symptoms. Children ...

10/09/2026

Supporting Files

Title : Associations of Maternal Peripregnancy Cannabis Use With Behavioral and Developmental Outcomes in Children With and Without Symptoms of Autism Spectrum Disorder: Study to Explore Early Development. Personal Author(s) : DiGuiseppi, Carolyn;Crume, Tessa;Holst, Brady;Aiona, Kaylynn;Van Dyke, Julia;Croen, Lisa A.;Daniels, Julie L.;Friedman, Sandra;Sabourin, Katherine R.;Schieve, Laura A.;Wiggins, Lisa;Windham, Gayle C.;Rosenberg, Cordelia Robinson; Published Date : January 2025 Pages in Document : 202-216 (25 pdf pages) Source : Autism Research : Official Journal of the International Society for Autism Research, 2025, v. 18, no. 1 DOI : https://doi.org/10.1002/aur.3284 Journal Title : Autism Research : Official Journal of the International Society for Autism Research
DiGuiseppi, C., Crume, T., Holst, B., Aiona, K., Van Dyke, J., Croen, L. A., Daniels, J. L., Friedman, S., Sabourin, K. R., Schieve, L. A., Wiggins, L., Windham, G. C., & Rosenberg, C. R. (2025). Associations of Maternal Peripregnancy Cannabis Use With Behavioral and Developmental Outcomes in Children With and Without Symptoms of Autism Spectrum Disorder: Study to Explore Early Development. Autism Research : Official Journal of the International Society for Autism Research, 18(1). https://doi.org/10.1002/aur.3284

DiGuiseppi, Carolyn, Tessa Crume, Brady Holst, Kaylynn Aiona, Julia Van Dyke, Lisa A. Croen, and Julie L. Daniels, et al.. "Associations of Maternal Peripregnancy Cannabis Use With Behavioral and Developmental Outcomes in Children With and Without Symptoms of Autism Spectrum Disorder: Study to Explore Early Development." Autism Research : Official Journal of the International Society for Autism Research 18, no. 1 (2025). https://doi.org/10.1002/aur.3284.

DiGuiseppi, Carolyn, et al. "Associations of Maternal Peripregnancy Cannabis Use With Behavioral and Developmental Outcomes in Children With and Without Symptoms of Autism Spectrum Disorder: Study to Explore Early Development." Autism Research : Official Journal of the International Society for Autism Research, vol. 18, no. 1, 2025. Stacks. https://doi.org/10.1002/aur.3284.
Export RIS Citation Information. TY - Journal Article AU - DiGuiseppi, Carolyn AU - Crume, Tessa AU - Holst, Brady AU - Aiona, Kaylynn AU - Van Dyke, Julia AU - Croen, Lisa A. AU - Daniels, Julie L. AU - Friedman, Sandra AU - Sabourin, Katherine R. AU - Schieve, Laura A. AU - Wiggins, Lisa AU - Windham, Gayle C. AU - Rosenberg, Cordelia Robinson AB - Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3 months preconception through delivery ("peripregnancy") with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30-68 months with ASD symptoms (i.e., met study criteria for ASD or had ASD symptoms on standardized assessments or community ASD diagnosis, N = 2734) and without ASD symptoms (other developmental delay/disorders or general population sample, N = 3454) were evaluated with the Child Behavior Checklist and Mullen Scales of Early Learning. We examined cannabis use during three time periods: peripregnancy, pregnancy, and only preconception. Peripregnancy cannabis exposure was reported for 6.0% of children with and 4.6% of children without ASD symptoms. Preconception-only cannabis use (versus no use) was associated with more aggressive behavior, emotional reactivity, and sleep problems in children with ASD symptoms, but not in children without ASD symptoms. Cannabis use during pregnancy was associated with increased attention and sleep problems in children with ASD symptoms; these associations did not differ significantly by ASD symptoms. Peripregnancy cannabis use was not associated with child developmental abilities regardless of ASD symptoms. In summary, associations of peripregnancy cannabis use with some behavioral outcomes differed in children with and without ASD symptoms. With rising cannabis use among pregnant women, future studies that examine a range of developmental risks associated with timing and patterns of cannabis use prior to conception as well as during pregnancy could inform clinical guidance. AB - Author manuscript AN - cdc:261862 C4 - PMC11785473 DO - https://doi.org/10.1002/aur.3284 IS - 1 J2 - Autism Research : Official Journal of the International Society for Autism Research KW - Pregnancy KW - Female KW - Marijuana Use KW - Prenatal Exposure Delayed Effects KW - Child KW - Autism Spectrum Disorder KW - Infant KW - Male KW - Humans KW - Child, Preschool KW - Child Behavior KW - Child Development KW - Adult KW - autism spectrum disorder KW - cannabis KW - child behavior KW - child preschool KW - developmental disabilities KW - pregnancy KW - prenatal risk factors KW - sleep wake disorders KW - Humans KW - Autism Spectrum Disorder KW - Female KW - Pregnancy KW - Male KW - Prenatal Exposure Delayed Effects KW - Child, Preschool KW - Child Development KW - Adult KW - Child KW - Marijuana Use KW - Child Behavior KW - Infant LA - eng PY - 2025 T2 - Autism Research : Official Journal of the International Society for Autism Research T2 - Autism Research : Official Journal of the International Society for Autism Research, 2025, v. 18, no. 1 TI - Associations of Maternal Peripregnancy Cannabis Use With Behavioral and Developmental Outcomes in Children With and Without Symptoms of Autism Spectrum Disorder: Study to Explore Early Development. VL - 18 UR - https://stacks.cdc.gov/view/cdc/261862 ER -
Associations Between Maternal Periconceptional Alcohol Consumption and Risk of Craniosynostosis Among Offspring, National Birth Defects Prevention Study, 1997-2011.

Fisher, Sarah C. ;

Romitti, Paul A.

December 2024 | Birth Defects Research, 2024, v. 116, no. 12

Previous studies of maternal alcohol consumption and craniosynostosis have reported null or inverse associations. We updated a previous analysis of National Birth Defects Prevention Study (NBDPS) data to further examine associations between maternal alcohol consumption and craniosynostosis.NBDPS was a multi-site, population-based case-control study ...

10/09/2026

Supporting Files

Title : Associations Between Maternal Periconceptional Alcohol Consumption and Risk of Craniosynostosis Among Offspring, National Birth Defects Prevention Study, 1997-2011. Personal Author(s) : Fisher, Sarah C.;Romitti, Paul A.;Tracy, Melissa;Howley, Meredith M.;Jabs, Ethylin Wang;Browne, Marilyn L.; Corporate Authors(s) : the National Birth Defects Prevention Study Published Date : December 2024 Pages in Document : e2420 (18 pdf pages) Source : Birth Defects Research, 2024, v. 116, no. 12 DOI : https://doi.org/10.1002/bdr2.2420 Journal Title : Birth Defects Research
Fisher, S. C., Romitti, P. A., Tracy, M., Howley, M. M., Jabs, E. W., & Browne, M. L. (2024). Associations Between Maternal Periconceptional Alcohol Consumption and Risk of Craniosynostosis Among Offspring, National Birth Defects Prevention Study, 1997-2011. Birth Defects Research, 116(12). https://doi.org/10.1002/bdr2.2420

Fisher, Sarah C., Paul A. Romitti, Melissa Tracy, Meredith M. Howley, Ethylin Wang Jabs, and Marilyn L. Browne. "Associations Between Maternal Periconceptional Alcohol Consumption and Risk of Craniosynostosis Among Offspring, National Birth Defects Prevention Study, 1997-2011." Birth Defects Research 116, no. 12 (2024). https://doi.org/10.1002/bdr2.2420.

Fisher, Sarah C., et al. "Associations Between Maternal Periconceptional Alcohol Consumption and Risk of Craniosynostosis Among Offspring, National Birth Defects Prevention Study, 1997-2011." Birth Defects Research, vol. 116, no. 12, 2024. Stacks. https://doi.org/10.1002/bdr2.2420.
Export RIS Citation Information. TY - Journal Article AU - Fisher, Sarah C. AU - Romitti, Paul A. AU - Tracy, Melissa AU - Howley, Meredith M. AU - Jabs, Ethylin Wang AU - Browne, Marilyn L. A2 - the National Birth Defects Prevention Study AB - Previous studies of maternal alcohol consumption and craniosynostosis have reported null or inverse associations. We updated a previous analysis of National Birth Defects Prevention Study (NBDPS) data to further examine associations between maternal alcohol consumption and craniosynostosis. AB - NBDPS was a multi-site, population-based case-control study. Mothers of craniosynostosis cases and randomly selected liveborn controls delivered during 1997-2011 completed a telephone interview about pregnancy exposures. We examined associations for self-reported periconceptional maternal alcohol consumption (during the month before conception through the third gestational month) and odds of craniosynostosis in offspring. We used logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for associations between any alcohol consumption and binge consumption and craniosynostosis, overall and by affected suture. Finally, we performed a probabilistic bias analysis using a range of assumptions about the sensitivity and specificity of self-reported consumption by case/control status. AB - We analyzed interview data from 1435 mothers of craniosynostosis cases and 11,216 mothers of controls. Periconceptional alcohol consumption prevalence was similar among case (36.9%) and control (38.2%) mothers. We observed point estimates near or below 1.0 for alcohol consumption (any and binge) and all suture subtypes of craniosynostosis, with all CIs including the null. Our bias-adjusted estimates for periconceptional alcohol consumption were higher than our conventional estimates but supported the null findings. AB - We observed primarily null associations between maternal periconceptional alcohol consumption and craniosynostosis. However, our findings do not diminish the prevailing clinical guidance in the United States that pregnant people should abstain from alcohol consumption. AB - Author manuscript AN - cdc:261861 C4 - PMC12927638 DO - https://doi.org/10.1002/bdr2.2420 IS - 12 J2 - Birth Defects Research KW - Pregnancy KW - Female KW - Risk Factors KW - Alcohol Drinking KW - Odds Ratio KW - Maternal Exposure KW - Case-Control Studies KW - Prenatal Exposure Delayed Effects KW - Humans KW - Craniosynostoses KW - Adult KW - craniosynostosis KW - birth defects KW - alcohol KW - pregnancy KW - NBDPS KW - bias KW - Humans KW - Female KW - Craniosynostoses KW - Pregnancy KW - Alcohol Drinking KW - Case-Control Studies KW - Adult KW - Risk Factors KW - Odds Ratio KW - Prenatal Exposure Delayed Effects KW - Maternal Exposure LA - eng PY - 2024 T2 - Birth Defects Research T2 - Birth Defects Research, 2024, v. 116, no. 12 TI - Associations Between Maternal Periconceptional Alcohol Consumption and Risk of Craniosynostosis Among Offspring, National Birth Defects Prevention Study, 1997-2011. VL - 116 UR - https://stacks.cdc.gov/view/cdc/261861 ER -
Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS-CoV-2 Pandemic, 2017-2022.

Cragan, Janet D. ;

Cho, Sook-Ja

December 2024 | Birth Defects Research, 2024, v. 116, no. 12

Reports from China describe an increase in the frequency of fetal situs inversus in 2023 after the country's "zero-Covid" policy was lifted, suggesting an association with maternal SARS-CoV-2 infection. However, a report of birth defects surveillance data from Scandinavia observed no sustained increase during the SARS-CoV-2 pandemic (2020-2022 vs. ...

10/09/2026

Supporting Files

Title : Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS-CoV-2 Pandemic, 2017-2022. Personal Author(s) : Cragan, Janet D.;Cho, Sook-Ja;Forestieri, Nina;Hort, Michele;Nestoridi, Eirini;Moore, Cynthia A.;Stallings, Erin;Gray, Elizabeth B.;Reefhuis, Jennita; Published Date : December 2024 Pages in Document : e2424 (8 pdf pages) Source : Birth Defects Research, 2024, v. 116, no. 12 DOI : https://doi.org/10.1002/bdr2.2424 Journal Title : Birth Defects Research
Cragan, J. D., Cho, S. J., Forestieri, N., Hort, M., Nestoridi, E., Moore, C. A., Stallings, E., Gray, E. B., & Reefhuis, J. (2024). Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS-CoV-2 Pandemic, 2017-2022. Birth Defects Research, 116(12). https://doi.org/10.1002/bdr2.2424

Cragan, Janet D., Sook-Ja Cho, Nina Forestieri, Michele Hort, Eirini Nestoridi, Cynthia A. Moore, Erin Stallings, Elizabeth B. Gray, and Jennita Reefhuis. "Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS-CoV-2 Pandemic, 2017-2022." Birth Defects Research 116, no. 12 (2024). https://doi.org/10.1002/bdr2.2424.

Cragan, Janet D., et al. "Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS-CoV-2 Pandemic, 2017-2022." Birth Defects Research, vol. 116, no. 12, 2024. Stacks. https://doi.org/10.1002/bdr2.2424.
Export RIS Citation Information. TY - Journal Article AU - Cragan, Janet D. AU - Cho, Sook-Ja AU - Forestieri, Nina AU - Hort, Michele AU - Nestoridi, Eirini AU - Moore, Cynthia A. AU - Stallings, Erin AU - Gray, Elizabeth B. AU - Reefhuis, Jennita AB - Reports from China describe an increase in the frequency of fetal situs inversus in 2023 after the country's "zero-Covid" policy was lifted, suggesting an association with maternal SARS-CoV-2 infection. However, a report of birth defects surveillance data from Scandinavia observed no sustained increase during the SARS-CoV-2 pandemic (2020-2022 vs. 2018-2019). We examined birth defects surveillance data to assess any increase in situs inversus in the U.S. during the SARS-CoV-2 pandemic. AB - We combined data from four population-based birth defects programs in Massachusetts, Minnesota, North Carolina, and Atlanta, Georgia, to compare the prevalence of situs inversus among infants and fetuses delivered before (2017-2019) and during (2021-2022) the SARS-CoV-2 pandemic. We defined situs inversus as mirror-image transposition of the heart and/or other organs, or primary ciliary dyskinesis with situs inversus, excluding isolated dextrocardia. The programs varied in the pregnancy outcomes included (live births ± non-live births); all included both prenatal and postnatal diagnoses. AB - We identified 294 infants and fetuses with situs inversus (6.8% non-live births). We estimated the combined prevalence per 10,000 live births as 1.72 during the pandemic versus 1.71 before the pandemic (OR = 1.005; 95% CI: 0.778-1.297). The estimated annual prevalence ranged from 1.41 in 2017 to 2.21 in 2019 with no significant trend across the study period (p = 0.39). AB - We did not observe an increase in situs inversus during the SARS-CoV-2 pandemic. Because information about SARS-CoV-2 infection among individual pregnancies was not available from all programs, we could not assess a specific association with maternal infection. AB - Author manuscript AN - cdc:261860 C4 - PMC11812594 DO - https://doi.org/10.1002/bdr2.2424 IS - 12 J2 - Birth Defects Research KW - Pregnancy Complications, Infectious KW - Pregnancy KW - Female KW - Situs Inversus KW - Pandemics KW - Prevalence KW - SARS-CoV-2 KW - Male KW - Humans KW - COVID-19 KW - Infant, Newborn KW - Pregnancy Outcome KW - birth defect KW - COVID-19 KW - laterality KW - pandemic KW - prevalence KW - SARS-CoV-2 KW - situs inversus KW - Humans KW - COVID-19 KW - Situs Inversus KW - Female KW - Prevalence KW - Pregnancy KW - SARS-CoV-2 KW - Infant, Newborn KW - Pandemics KW - Pregnancy Complications, Infectious KW - Male KW - Pregnancy Outcome LA - eng PY - 2024 T2 - Birth Defects Research T2 - Birth Defects Research, 2024, v. 116, no. 12 TI - Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS-CoV-2 Pandemic, 2017-2022. VL - 116 UR - https://stacks.cdc.gov/view/cdc/261860 ER -
Patterns of Medication For Opioid Use Disorder During Pregnancy, 7 Clinical Sites, MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021.

Tran, Emmy L. ;

Dorsey, Amanda N.

March 13, 2025 | Journal of Addiction Medicine, 2025, v. 19, no. 2

To describe patterns of medication for opioid use disorder (MOUD) during pregnancies in the opioid use disorder (OUD) cohort of MAT-LINK, a sentinel surveillance network of pregnancies at US clinical sites.Seven clinical sites providing care for pregnant people with OUD collected electronic health record data. Pregnancies were included in this anal ...

10/09/2026

Supporting Files

Title : Patterns of Medication For Opioid Use Disorder During Pregnancy, 7 Clinical Sites, MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021. Personal Author(s) : Tran, Emmy L.;Dorsey, Amanda N.;Miele, Kathryn;Gilboa, Suzanne M.;Gosdin, Lucas;Terplan, Mishka;Sanjuan, Pilar M.;Seligman, Neil S.;Wright, Tanner;Wachman, Elisha M.;Smid, Marcela;Henninger, Michelle;Leeman, Lawrence;Schneider, Patrick D.;Rood, Kara;Louis, Judette M.;Caveglia, Sarah;Davidson, Autumn;Shakib, Julie;Shrestha, Hira;Meaney-Delman, Dana M.;Kim, Shin Y.; Published Date : March 13, 2025 Pages in Document : 208-215 (18 pdf pages) Source : Journal of Addiction Medicine, 2025, v. 19, no. 2 DOI : https://doi.org/10.1097/ADM.0000000000001426 Journal Title : Journal of Addiction Medicine
Tran, E. L., Dorsey, A. N., Miele, K., Gilboa, S. M., Gosdin, L., Terplan, M., Sanjuan, P. M., Seligman, N. S., Wright, T., Wachman, E. M., Smid, M., Henninger, M., Leeman, L., Schneider, P. D., Rood, K., Louis, J. M., Caveglia, S., Davidson, A., Shakib, J., ... Kim, S. Y. (2025). Patterns of Medication For Opioid Use Disorder During Pregnancy, 7 Clinical Sites, MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021. Journal of Addiction Medicine, 19(2). https://doi.org/10.1097/ADM.0000000000001426

Tran, Emmy L., Amanda N. Dorsey, Kathryn Miele, Suzanne M. Gilboa, Lucas Gosdin, Mishka Terplan, and Pilar M. Sanjuan, et al.. "Patterns of Medication For Opioid Use Disorder During Pregnancy, 7 Clinical Sites, MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021." Journal of Addiction Medicine 19, no. 2 (2025). https://doi.org/10.1097/ADM.0000000000001426.

Tran, Emmy L., et al. "Patterns of Medication For Opioid Use Disorder During Pregnancy, 7 Clinical Sites, MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021." Journal of Addiction Medicine, vol. 19, no. 2, 2025. Stacks. https://doi.org/10.1097/ADM.0000000000001426.
Export RIS Citation Information. TY - Journal Article AU - Tran, Emmy L. AU - Dorsey, Amanda N. AU - Miele, Kathryn AU - Gilboa, Suzanne M. AU - Gosdin, Lucas AU - Terplan, Mishka AU - Sanjuan, Pilar M. AU - Seligman, Neil S. AU - Wright, Tanner AU - Wachman, Elisha M. AU - Smid, Marcela AU - Henninger, Michelle AU - Leeman, Lawrence AU - Schneider, Patrick D. AU - Rood, Kara AU - Louis, Judette M. AU - Caveglia, Sarah AU - Davidson, Autumn AU - Shakib, Julie AU - Shrestha, Hira AU - Meaney-Delman, Dana M. AU - Kim, Shin Y. AB - To describe patterns of medication for opioid use disorder (MOUD) during pregnancies in the opioid use disorder (OUD) cohort of MAT-LINK, a sentinel surveillance network of pregnancies at US clinical sites. AB - Seven clinical sites providing care for pregnant people with OUD collected electronic health record data. Pregnancies were included in this analysis if (1) the pregnancy outcome occurred between January 2014 and August 2021, (2) the person had OUD, and (3) there was any electronic health record-documented MOUD during pregnancy. Analyses describing MOUD type, demographic characteristics, and timing during pregnancy were performed. AB - Among 3911 pregnancies with any documented MOUD, more than 90% of pregnancies with methadone were to publicly insured people, which was greater than percentages for pregnancies with other MOUD. Buprenorphine with naloxone and naltrexone were two MOUD types that were increasingly common among pregnant people in recent years. In most pregnancies, prenatal care and MOUD were first documented in the same trimester. During the first, second, and third trimesters, there were 37%, 61%, and 91% of pregnancies with MOUD, respectively. Approximately 87% (n = 3412) had only 1 documented MOUD type, versus 2 or 3 types. However, discontinuity in MOUD across trimesters was still observed. AB - In MAT-LINK's OUD cohort, the overall frequency of MOUD improved over the course of pregnancy. Contextual factors, such as insurance status and year of pregnancy outcome, might influence MOUD type. Prenatal care and MOUD might be facilitators for one another; however, there are still opportunities to improve early linkage and continuous access to both prenatal care and MOUD during pregnancy. AB - Author manuscript AN - cdc:261859 C4 - PMC11903160 DO - https://doi.org/10.1097/ADM.0000000000001426 IS - 2 J2 - Journal of Addiction Medicine KW - Pregnancy KW - Female KW - Buprenorphine KW - Electronic Health Records KW - Opioid-Related Disorders KW - Young Adult KW - Buprenorphine, Naloxone Drug Combination KW - Pregnancy Complications KW - Prenatal Care KW - Methadone KW - Narcotic Antagonists KW - Humans KW - Pregnancy Outcome KW - Adult KW - Opiate Substitution Treatment KW - opioid-related disorders KW - pregnancy KW - prenatal care KW - electronic health records KW - sentinel surveillance KW - Humans KW - Pregnancy KW - Female KW - Opioid-Related Disorders KW - Adult KW - Pregnancy Complications KW - Opiate Substitution Treatment KW - Prenatal Care KW - Methadone KW - Young Adult KW - Narcotic Antagonists KW - Buprenorphine KW - Buprenorphine, Naloxone Drug Combination KW - Pregnancy Outcome KW - Electronic Health Records LA - eng PY - 2025 T2 - Journal of Addiction Medicine T2 - Journal of Addiction Medicine, 2025, v. 19, no. 2 TI - Patterns of Medication For Opioid Use Disorder During Pregnancy, 7 Clinical Sites, MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021. VL - 19 UR - https://stacks.cdc.gov/view/cdc/261859 ER -
Post-licensure Safety Surveillance of 20-Valent Pneumococcal Conjugate Vaccine (PCV20) Among US Adults in the Vaccine Adverse Event Reporting System (VAERS).

Oliveira, Mayra ;

Marquez, Paige

March 2025 | Drug Safety, 2025, v. 48, no. 3

On June 8, 2021, a new 20-valent pneumococcal conjugate vaccine (PCV20, PREVNAR 20, Pfizer, Inc.) was licensed for use in adults aged ≥ 18 years by the US Food and Drug Administration (FDA).To describe reports to the Vaccine Adverse Event Reporting System (VAERS) after administration of the 20-valent pneumococcal conjugate vaccine in adults.We sear ...

10/09/2026

Supporting Files

Title : Post-licensure Safety Surveillance of 20-Valent Pneumococcal Conjugate Vaccine (PCV20) Among US Adults in the Vaccine Adverse Event Reporting System (VAERS). Personal Author(s) : Oliveira, Mayra;Marquez, Paige;Ennulat, Carol;Blanc, Phillip;Welsh, Kerry;Nair, Narayan;Taminato, Monica;Moro, Pedro L.; Published Date : March 2025 Pages in Document : 279-286 (15 pdf pages) Source : Drug Safety, 2025, v. 48, no. 3 DOI : https://doi.org/10.1007/s40264-024-01498-2 Journal Title : Drug Safety
Oliveira, M., Marquez, P., Ennulat, C., Blanc, P., Welsh, K., Nair, N., Taminato, M., & Moro, P. L. (2025). Post-licensure Safety Surveillance of 20-Valent Pneumococcal Conjugate Vaccine (PCV20) Among US Adults in the Vaccine Adverse Event Reporting System (VAERS). Drug Safety, 48(3). https://doi.org/10.1007/s40264-024-01498-2

Oliveira, Mayra, Paige Marquez, Carol Ennulat, Phillip Blanc, Kerry Welsh, Narayan Nair, Monica Taminato, and Pedro L. Moro. "Post-licensure Safety Surveillance of 20-Valent Pneumococcal Conjugate Vaccine (PCV20) Among US Adults in the Vaccine Adverse Event Reporting System (VAERS)." Drug Safety 48, no. 3 (2025). https://doi.org/10.1007/s40264-024-01498-2.

Oliveira, Mayra, et al. "Post-licensure Safety Surveillance of 20-Valent Pneumococcal Conjugate Vaccine (PCV20) Among US Adults in the Vaccine Adverse Event Reporting System (VAERS)." Drug Safety, vol. 48, no. 3, 2025. Stacks. https://doi.org/10.1007/s40264-024-01498-2.
Export RIS Citation Information. TY - Journal Article AU - Oliveira, Mayra AU - Marquez, Paige AU - Ennulat, Carol AU - Blanc, Phillip AU - Welsh, Kerry AU - Nair, Narayan AU - Taminato, Monica AU - Moro, Pedro L. AB - On June 8, 2021, a new 20-valent pneumococcal conjugate vaccine (PCV20, PREVNAR 20 AB - , Pfizer, Inc.) was licensed for use in adults aged ≥ 18 years by the US Food and Drug Administration (FDA). AB - To describe reports to the Vaccine Adverse Event Reporting System (VAERS) after administration of the 20-valent pneumococcal conjugate vaccine in adults. AB - We searched the VAERS for reports of adverse events involving persons aged ≥ 19 years who received PCV20 during October 20, 2021, through December 31, 2023. Our evaluation included automated analysis of reports, clinical review of serious reports and pre-specified events of special interest, empirical Bayesian data mining to assess for disproportionate reporting, and estimation of reporting rates for reports of Guillain-Barré syndrome (GBS). AB - The VAERS received 1976 reports after PCV20 administration in persons aged ≥ 19 years (6% of reports involved serious events). The most common adverse events among persons aged 19-64 years (n = 798) were injection-site reactions (231, 29%), pain (134, 17%), erythema (118, 15%), and fever (117, 15%). For persons aged ≥ 65 years (n = 1178), the most common adverse events were injection-site reactions (417, 35%), pain (180, 15%), pain in extremity (162, 14%), and erythema (158, 13%). A data mining alert (EB05 = 3.812) for the MedDRA Preferred Term "Guillain-Barre syndrome" was observed for serious reports. Clinical review verified 11 of 20 GBS reports; 7/11 vaccine recipients were aged ≥ 65 years. Among the 11 verified cases, the median time from vaccination to symptom onset was 14 days. Five persons received another vaccine on the same visit. The reporting rate of GBS after PCV20 receipt was 0.5 cases per million doses distributed. No other safety concern was identified. AB - During the period of this post-licensure review of PCV20, we found most reports were non-serious and comprised mostly local and systemic (e.g., fever) reactions consistent with prelicensure studies. In serious reports, we also identified a data mining alert for GBS after receipt of PCV20, which Centers for Disease Control and Prevention and the FDA are investigating further. No other new or unexpected safety concern was identified. AB - Author manuscript AN - cdc:261858 C4 - PMC11973709 DO - https://doi.org/10.1007/s40264-024-01498-2 IS - 3 J2 - Drug Safety KW - Product Surveillance, Postmarketing KW - Drug-Related Side Effects and Adverse Reactions KW - Female KW - Vaccines, Conjugate KW - Guillain-Barre Syndrome KW - Aged KW - Young Adult KW - Pneumococcal Vaccines KW - Aged, 80 and over KW - Adverse Drug Reaction Reporting Systems KW - United States Food and Drug Administration KW - Male KW - Humans KW - Middle Aged KW - Adult KW - Humans KW - Adverse Drug Reaction Reporting Systems KW - Product Surveillance, Postmarketing KW - Adult KW - Pneumococcal Vaccines KW - Middle Aged KW - Aged KW - Male KW - Female KW - Young Adult KW - United States Food and Drug Administration KW - Guillain-Barre Syndrome KW - Drug-Related Side Effects and Adverse Reactions KW - Vaccines, Conjugate KW - Aged, 80 and over LA - eng PY - 2025 T2 - Drug Safety T2 - Drug Safety, 2025, v. 48, no. 3 TI - Post-licensure Safety Surveillance of 20-Valent Pneumococcal Conjugate Vaccine (PCV20) Among US Adults in the Vaccine Adverse Event Reporting System (VAERS). VL - 48 UR - https://stacks.cdc.gov/view/cdc/261858 ER -
Prevalence of Mild and Severe Cognitive Impairment in World Trade Center Exposed Fire Department of the City of New York (FDNY) and General Emergency Responders.

Mann, Frank D. ;

Mueller, Alexandra K.

February 2025 | American Journal of Industrial Medicine, 2025, v. 68, no. 2

The emergency personnel who responded to the World Trade Center (WTC) attacks endured severe occupational exposures, yet the prevalence of cognitive impairment remains unknown among WTC-exposed-FDNY-responders. The present study screened for mild and severe cognitive impairment in WTC-exposed FDNY responders using objective tests, compared prevalen ...

10/09/2026

Supporting Files

Title : Prevalence of Mild and Severe Cognitive Impairment in World Trade Center Exposed Fire Department of the City of New York (FDNY) and General Emergency Responders. Personal Author(s) : Mann, Frank D.;Mueller, Alexandra K.;Zeig-Owens, Rachel;Choi, Jaeun;Prezant, David J.;Carr, Melissa M.;Fels, Alicia M.;Hennington, Christina M.;Armstrong, Megan P.;Barber, Alissa;Fontana, Ashley E.;Kroll, Cassandra H.;Chow, Kevin;Melendez, Onix A.;Smith, Abigail J.;Luft, Benjamin J.;Hall, Charles B.;Clouston, Sean A. P.; Published Date : February 2025 Pages in Document : 160-174 (25 pdf pages) Source : American Journal of Industrial Medicine, 2025, v. 68, no. 2 DOI : https://doi.org/10.1002/ajim.23685 Journal Title : American Journal of Industrial Medicine
Mann, F. D., Mueller, A. K., Zeig-Owens, R., Choi, J., Prezant, D. J., Carr, M. M., Fels, A. M., Hennington, C. M., Armstrong, M. P., Barber, A., Fontana, A. E., Kroll, C. H., Chow, K., Melendez, O. A., Smith, A. J., Luft, B. J., Hall, C. B., & Clouston, S. A. P. (2025). Prevalence of Mild and Severe Cognitive Impairment in World Trade Center Exposed Fire Department of the City of New York (FDNY) and General Emergency Responders. American Journal of Industrial Medicine, 68(2). https://doi.org/10.1002/ajim.23685

Mann, Frank D., Alexandra K. Mueller, Rachel Zeig-Owens, Jaeun Choi, David J. Prezant, Melissa M. Carr, and Alicia M. Fels, et al.. "Prevalence of Mild and Severe Cognitive Impairment in World Trade Center Exposed Fire Department of the City of New York (FDNY) and General Emergency Responders." American Journal of Industrial Medicine 68, no. 2 (2025). https://doi.org/10.1002/ajim.23685.

Mann, Frank D., et al. "Prevalence of Mild and Severe Cognitive Impairment in World Trade Center Exposed Fire Department of the City of New York (FDNY) and General Emergency Responders." American Journal of Industrial Medicine, vol. 68, no. 2, 2025. Stacks. https://doi.org/10.1002/ajim.23685.
Export RIS Citation Information. TY - Journal Article AU - Mann, Frank D. AU - Mueller, Alexandra K. AU - Zeig-Owens, Rachel AU - Choi, Jaeun AU - Prezant, David J. AU - Carr, Melissa M. AU - Fels, Alicia M. AU - Hennington, Christina M. AU - Armstrong, Megan P. AU - Barber, Alissa AU - Fontana, Ashley E. AU - Kroll, Cassandra H. AU - Chow, Kevin AU - Melendez, Onix A. AU - Smith, Abigail J. AU - Luft, Benjamin J. AU - Hall, Charles B. AU - Clouston, Sean A. P. AB - The emergency personnel who responded to the World Trade Center (WTC) attacks endured severe occupational exposures, yet the prevalence of cognitive impairment remains unknown among WTC-exposed-FDNY-responders. The present study screened for mild and severe cognitive impairment in WTC-exposed FDNY responders using objective tests, compared prevalence rates to a cohort of non-FDNY WTC-exposed responders, and descriptively to meta-analytic estimates of MCI from global, community, and clinical populations. AB - A sample of WTC-exposed-FDNY responders (n = 343) was recruited to complete an extensive battery of cognitive, psychological, and physical tests. The prevalences of domain-specific impairments were estimated based on the results of norm-referenced tests, and the Montreal Cognitive Assessment (MoCA), Jak/Bondi criteria, Petersen criteria, and the National Institute on Aging and Alzheimer's Association (NIA-AA) criteria were used to diagnose MCI. NIA-AA criteria were also used to diagnose severe cognitive impairment. Generalized linear models and propensity score matching were used to compare prevalence estimates of cognitive impairment to a large sample of WTC-exposed-non-FDNY responders from the General Responder Cohort (GRC; n = 7102) who completed the MoCA during a similar time frame. AB - Among FDNY responders under 65 years, the unadjusted prevalence of MCI varied from 52.57% to 60.32% depending on the operational definition of MCI, apart from using a conservative cut-off applied to MoCA total scores (18 < MoCA < 23), which yielded a markedly lower crude prevalence (24.31%) compared to alternative criteria. Using propensity score matching, the prevalence of MCI was significantly higher among WTC-exposed FDNY responders, compared to WTC-exposed GRC responders (adjusted RR = 1.13 (CI 95% = 1.07-1.20, p < 0.001), and descriptively higher than meta-analytic estimates from different global, community, and clinical populations. Following NIA-AA diagnostic guidelines, 4.96% of WTC-exposed-FDNY-responders met the criteria for severe impairments (95% CI = 2.91-7.82), a prevalence that remained largely unchanged after excluding responders over the age of 65 years. AB - There is a high prevalence of mild and severe cognitive impairment among WTC-responders, highlighting the putative role of occupational, environmental, and disaster-related exposures in the etiology of accelerated cognitive decline. AB - Author manuscript AN - cdc:261857 C4 - PMC12175152 DO - https://doi.org/10.1002/ajim.23685 IS - 2 J2 - American Journal of Industrial Medicine KW - Occupational Exposure KW - Female KW - Emergency Responders KW - Aged KW - Cognitive Dysfunction KW - Neuropsychological Tests KW - Occupational Diseases KW - Firefighters KW - Prevalence KW - Male KW - Middle Aged KW - Humans KW - September 11 Terrorist Attacks KW - Adult KW - Humans KW - September 11 Terrorist Attacks KW - Cognitive Dysfunction KW - Prevalence KW - Male KW - Emergency Responders KW - Female KW - Middle Aged KW - Adult KW - Occupational Exposure KW - Occupational Diseases KW - Neuropsychological Tests KW - Firefighters KW - Aged LA - eng PY - 2025 T2 - American Journal of Industrial Medicine T2 - American Journal of Industrial Medicine, 2025, v. 68, no. 2 TI - Prevalence of Mild and Severe Cognitive Impairment in World Trade Center Exposed Fire Department of the City of New York (FDNY) and General Emergency Responders. VL - 68 UR - https://stacks.cdc.gov/view/cdc/261857 ER -
Workplace Injury and Death: a National Overview of Changing Trends by Sex, United States 1998-2022.

Hendricks, Kitty J. ;

Hendricks, Scott A.

February 2025 | American Journal of Industrial Medicine, 2025, v. 68, no. 2

Women represent a substantial portion of the US workforce. However, injury and fatality rates for female workers have, historically, remained lower than rates for male workers. Fatal occupational data from the Census of Fatal Occupational Injuries (CFOI) and nonfatal injury data from the National Electronic Injury Surveillance System-Occupational S ...

10/09/2026

Supporting Files

Title : Workplace Injury and Death: a National Overview of Changing Trends by Sex, United States 1998-2022. Personal Author(s) : Hendricks, Kitty J.;Hendricks, Scott A.;Marsh, Suzanne M.; Published Date : February 2025 Pages in Document : 194-201 (14 pdf pages) Source : American Journal of Industrial Medicine, 2025, v. 68, no. 2 DOI : https://doi.org/10.1002/ajim.23687 Journal Title : American Journal of Industrial Medicine
Hendricks, K. J., Hendricks, S. A., & Marsh, S. M. (2025). Workplace Injury and Death: a National Overview of Changing Trends by Sex, United States 1998-2022. American Journal of Industrial Medicine, 68(2). https://doi.org/10.1002/ajim.23687

Hendricks, Kitty J., Scott A. Hendricks, and Suzanne M. Marsh. "Workplace Injury and Death: a National Overview of Changing Trends by Sex, United States 1998-2022." American Journal of Industrial Medicine 68, no. 2 (2025). https://doi.org/10.1002/ajim.23687.

Hendricks, Kitty J., et al. "Workplace Injury and Death: a National Overview of Changing Trends by Sex, United States 1998-2022." American Journal of Industrial Medicine, vol. 68, no. 2, 2025. Stacks. https://doi.org/10.1002/ajim.23687.
Export RIS Citation Information. TY - Journal Article AU - Hendricks, Kitty J. AU - Hendricks, Scott A. AU - Marsh, Suzanne M. AB - Women represent a substantial portion of the US workforce. However, injury and fatality rates for female workers have, historically, remained lower than rates for male workers. Fatal occupational data from the Census of Fatal Occupational Injuries (CFOI) and nonfatal injury data from the National Electronic Injury Surveillance System-Occupational Supplement (NEISS-Work) for the years 1998-2022 were examined to produce rate ratios of male to female fatal and nonfatal occupational injury rates for all workers in the United States. Auto-regressive linear models were developed to analyze rate ratios by sex for fatal and nonfatal occupational injuries by age group, injury event, and select industries to determine if female occupational fatal and nonfatal injury rates were following trends comparable to male rates. Over the 25-year study period, male injury and fatality rates were consistently higher than females. Occupational fatality rates for males were more than nine times higher than female rates, and for nonfatal occupational injuries, male rates were 1.4 times higher than female rates. These analyses indicate that the differences in nonfatal injury rates by sex may be attenuating, however, the large gap by sex in workplace fatalities has remained unchanged. Occupational safety and health research with a more specific focus on these sex differences is needed to gain a clearer understanding of how sex differences affect hiring, job training, task assignment and completion, and injury risk, to identify areas where prevention efforts could be most successful. AB - Author manuscript AN - cdc:261856 C4 - PMC11856517 DO - https://doi.org/10.1002/ajim.23687 IS - 2 J2 - American Journal of Industrial Medicine KW - Adolescent KW - Female KW - Aged KW - Occupational Injuries KW - Accidents, Occupational KW - Young Adult KW - Workplace KW - Sex Factors KW - Sex Distribution KW - Male KW - Middle Aged KW - Humans KW - Adult KW - occupational fatalities KW - occupational injury KW - rate ratios KW - sex KW - trends KW - Humans KW - Male KW - Female KW - Occupational Injuries KW - Adult KW - Middle Aged KW - Accidents, Occupational KW - Sex Distribution KW - Young Adult KW - Adolescent KW - Sex Factors KW - Aged KW - Workplace LA - eng PY - 2025 T2 - American Journal of Industrial Medicine T2 - American Journal of Industrial Medicine, 2025, v. 68, no. 2 TI - Workplace Injury and Death: a National Overview of Changing Trends by Sex, United States 1998-2022. VL - 68 UR - https://stacks.cdc.gov/view/cdc/261856 ER -
Hospital-level Variation in Cardiac Rehabilitation Metrics.

Pollack, Lisa M. ;

Chang, Anping

April 2025 | American Heart Journal, 2025, v. 282

To inform the delivery of cardiac rehabilitation (CR) care nationwide at the hospital level, we described hospital-level variation in CR metrics, overall and stratified by the hospital's tier of cardiac care provided.This retrospective cohort analysis used Medicare fee-for-service (FFS) data (2018-2020), Parts A and B, and American Hospital Associa ...

10/09/2026

Supporting Files

Title : Hospital-level Variation in Cardiac Rehabilitation Metrics. Personal Author(s) : Pollack, Lisa M.;Chang, Anping;Thompson, Michael P.;Keteyian, Steven J.;Stolp, Haley;Wall, Hilary K.;Sperling, Laurence S.;Jackson, Sandra L.; Published Date : April 2025 Pages in Document : 58-69 (19 pdf pages) Source : American Heart Journal, 2025, v. 282 DOI : https://doi.org/10.1016/j.ahj.2024.12.004 Journal Title : American Heart Journal
Pollack, L. M., Chang, A., Thompson, M. P., Keteyian, S. J., Stolp, H., Wall, H. K., Sperling, L. S., & Jackson, S. L. (2025). Hospital-level Variation in Cardiac Rehabilitation Metrics. American Heart Journal, 282. https://doi.org/10.1016/j.ahj.2024.12.004

Pollack, Lisa M., Anping Chang, Michael P. Thompson, Steven J. Keteyian, Haley Stolp, Hilary K. Wall, Laurence S. Sperling, and Sandra L. Jackson. "Hospital-level Variation in Cardiac Rehabilitation Metrics." American Heart Journal 282 (2025). https://doi.org/10.1016/j.ahj.2024.12.004.

Pollack, Lisa M., et al. "Hospital-level Variation in Cardiac Rehabilitation Metrics." American Heart Journal, vol. 282, 2025. Stacks. https://doi.org/10.1016/j.ahj.2024.12.004.
Export RIS Citation Information. TY - Journal Article AU - Pollack, Lisa M. AU - Chang, Anping AU - Thompson, Michael P. AU - Keteyian, Steven J. AU - Stolp, Haley AU - Wall, Hilary K. AU - Sperling, Laurence S. AU - Jackson, Sandra L. AB - To inform the delivery of cardiac rehabilitation (CR) care nationwide at the hospital level, we described hospital-level variation in CR metrics, overall and stratified by the hospital's tier of cardiac care provided. AB - This retrospective cohort analysis used Medicare fee-for-service (FFS) data (2018-2020), Parts A and B, and American Hospital Association (AHA) data (2018). We included beneficiaries with an acute myocardial infarction (AMI), percutaneous coronary intervention (PCI), or coronary artery bypass graft (CABG) in 2018, aged ≥65 years, and continuously enrolled in a FFS plan. We calculated hospital-level metrics for hospitals with ≥20 CR-qualifying events, which were identified using diagnostic/procedure codes. Claims for CR were identified by Healthcare Common Procedure Coding System (HCPCS) codes. We used multi-level models to examine patient- and hospital-level factors associated with CR metrics. Hospitals were stratified by tier of cardiac care provided (comprehensive, AMI/PCI, AMI-only care). AB - Across the US, 2,212 hospitals treated individuals aged ≥65 years with a CR-qualifying event in 2018. By tier of cardiac care, 44.4% of hospitals provided comprehensive care, 31.2% provided AMI/PCI care, and 24.4% provided AMI-only care. Across all hospitals, there was substantial variation in CR enrollment (median 19.6%, interquartile range [IQR] = 7.0%, 32.8%). Among hospitals with enrollment (n = 1,866), median time to enrollment was 55.0 days (IQR = 41.0, 71.0), median number of CR sessions was 26.0 (IQR = 23.0, 29.0), and median percent completion was 26.0% (IQR = 10.5%, 41.2%). There was also substantial variation in CR performance metrics among hospitals within each tier of cardiac care (eg, median percent CR enrollment was 30.7% [IQR = 20.7%-41.3%] among comprehensive care hospitals, 18.6% [IQR = 9.5%-27.7%] among AMI/PCI hospitals, and 0.0% [IQR = 0.0%-7.7%] among AMI-only hospitals). In adjusted analyses, characteristics associated with lower odds of CR enrollment included patient-level factors (older age, female sex, non-White race or ethnicity), and hospital-level factors (for-profit ownership, regions other than the Midwest, rural location, medium/large hospital size). AB - This is the first national, hospital-level analysis of CR metrics among Medicare beneficiaries. Substantial variation across hospitals, including peer hospitals within the same tier of cardiac care, indicates opportunities for hospital-level quality improvement strategies to improve CR referral and participation metrics. AB - Author manuscript AN - cdc:261855 C4 - PMC11850174 DO - https://doi.org/10.1016/j.ahj.2024.12.004 J2 - American Heart Journal KW - Medicare KW - Female KW - Myocardial Infarction KW - Aged KW - Fee-for-Service Plans KW - Retrospective Studies KW - Cardiac Rehabilitation KW - Aged, 80 and over KW - Hospitals KW - Percutaneous Coronary Intervention KW - Male KW - Humans KW - Coronary Artery Bypass KW - Humans KW - Aged KW - Female KW - Retrospective Studies KW - Cardiac Rehabilitation KW - Male KW - Percutaneous Coronary Intervention KW - Medicare KW - Myocardial Infarction KW - Hospitals KW - Coronary Artery Bypass KW - Fee-for-Service Plans KW - Aged, 80 and over LA - eng PY - 2025 T2 - American Heart Journal T2 - American Heart Journal, 2025, v. 282 TI - Hospital-level Variation in Cardiac Rehabilitation Metrics. VL - 282 UR - https://stacks.cdc.gov/view/cdc/261855 ER -
Alcohol Consumption Does Not Modify the Polygenic Risk Score-Based Genetic Risk of Breast Cancer in Postmenopausal Women: Atherosclerosis Risk in Communities Study.

Zhang, Minghui ;

Ru, Meng

February 2025 | Cancer Prevention Research (Philadelphia, Pa.), 2025, v. 18, no. 2

High genetic risk and alcohol consumption ≥1 drink/day are associated with increased breast cancer risk. However, the interaction between alcohol and genetics on breast cancer risk is poorly understood, including in populations not enriched with daily drinkers. We prospectively studied 5,651 White and Black postmenopausal women in the Atheroscleros ...

10/09/2026

Supporting Files

Title : Alcohol Consumption Does Not Modify the Polygenic Risk Score-Based Genetic Risk of Breast Cancer in Postmenopausal Women: Atherosclerosis Risk in Communities Study. Personal Author(s) : Zhang, Minghui;Ru, Meng;Zhang, Jingning;Wang, Ziqiao;Lu, Jiayun;Butler, Kenneth R.;Chatterjee, Nilanjan;Couper, David J.;Prizment, Anna E.;Soori, Mehrnoosh M.;Visvanathan, Kala;Zahnow, Cynthia A.;Joshu, Corinne E.;Platz, Elizabeth A.; Published Date : February 2025 Pages in Document : 73-83 (22 pdf pages) Source : Cancer Prevention Research (Philadelphia, Pa.), 2025, v. 18, no. 2 DOI : https://doi.org/10.1158/1940-6207.CAPR-24-0208 Journal Title : Cancer Prevention Research (Philadelphia, Pa.)
Zhang, M., Ru, M., Zhang, J., Wang, Z., Lu, J., Butler, K. R., Chatterjee, N., Couper, D. J., Prizment, A. E., Soori, M. M., Visvanathan, K., Zahnow, C. A., Joshu, C. E., & Platz, E. A. (2025). Alcohol Consumption Does Not Modify the Polygenic Risk Score-Based Genetic Risk of Breast Cancer in Postmenopausal Women: Atherosclerosis Risk in Communities Study. Cancer Prevention Research (Philadelphia, Pa.), 18(2). https://doi.org/10.1158/1940-6207.CAPR-24-0208

Zhang, Minghui, Meng Ru, Jingning Zhang, Ziqiao Wang, Jiayun Lu, Kenneth R. Butler, and Nilanjan Chatterjee, et al.. "Alcohol Consumption Does Not Modify the Polygenic Risk Score-Based Genetic Risk of Breast Cancer in Postmenopausal Women: Atherosclerosis Risk in Communities Study." Cancer Prevention Research (Philadelphia, Pa.) 18, no. 2 (2025). https://doi.org/10.1158/1940-6207.CAPR-24-0208.

Zhang, Minghui, et al. "Alcohol Consumption Does Not Modify the Polygenic Risk Score-Based Genetic Risk of Breast Cancer in Postmenopausal Women: Atherosclerosis Risk in Communities Study." Cancer Prevention Research (Philadelphia, Pa.), vol. 18, no. 2, 2025. Stacks. https://doi.org/10.1158/1940-6207.CAPR-24-0208.
Export RIS Citation Information. TY - Journal Article AU - Zhang, Minghui AU - Ru, Meng AU - Zhang, Jingning AU - Wang, Ziqiao AU - Lu, Jiayun AU - Butler, Kenneth R. AU - Chatterjee, Nilanjan AU - Couper, David J. AU - Prizment, Anna E. AU - Soori, Mehrnoosh M. AU - Visvanathan, Kala AU - Zahnow, Cynthia A. AU - Joshu, Corinne E. AU - Platz, Elizabeth A. AB - High genetic risk and alcohol consumption ≥1 drink/day are associated with increased breast cancer risk. However, the interaction between alcohol and genetics on breast cancer risk is poorly understood, including in populations not enriched with daily drinkers. We prospectively studied 5,651 White and Black postmenopausal women in the Atherosclerosis Risk in Communities study. Alcohol intake was assessed by a food frequency questionnaire. The 313-SNP polygenic risk score (PRS) was calculated. Breast cancer cases were ascertained primarily by cancer registry linkage through 2015. Multivariable Cox regression was used to estimate HRs and 95% confidence intervals (CI) for the association of PRS and current ethanol intake with breast cancer, and their interaction. Of these individuals, 50.6% were current drinkers, and of them, 50.8% drank <1 drink/week and 12.8% drank >7 drinks/week. A higher PRS was associated with a higher breast cancer risk among White (HR1-SD, 1.48; 95% CI, 1.34-1.65) and Black (HR1-SD, 1.15; 95% CI, 0.96-1.38) women. Positive associations were not observed between current ethanol intake and breast cancer risk (White: HR13 g/week, 1.00; 95% CI, 0.98-1.03; Black: HR, 0.83; 95% CI, 0.69-1.00). Among both White and Black women, PRS generally seemed to be positively associated with risk in drinkers and nondrinkers. There was no evidence of a PRS-ethanol intake interaction among White or Black women. Patterns in Black women were similar when using an 89-SNP PRS developed among African ancestry women. In conclusion, in a prospective analysis of White and Black postmenopausal women in a study population not enriched with daily drinkers, our findings suggest that alcohol drinking does not modify the PRS-based genetic risk of breast cancer. Prevention Relevance: Although our findings suggest that alcohol drinking does not modify the PRS-based genetic risk of breast cancer among White and Black women with lower alcohol intake, nevertheless, women should consider limiting alcohol consumption as a general cancer prevention strategy, as indicated in dietary guidelines. AB - Author manuscript AN - cdc:261854 C4 - PMC11790378 DO - https://doi.org/10.1158/1940-6207.CAPR-24-0208 IS - 2 J2 - Cancer Prevention Research (Philadelphia, Pa.) KW - Multifactorial Inheritance KW - Female KW - White KW - Postmenopause KW - Alcohol Drinking KW - Genetic Predisposition to Disease KW - Prospective Studies KW - Aged KW - Genetic Risk Score KW - Breast Neoplasms KW - Risk Factors KW - Follow-Up Studies KW - Polymorphism, Single Nucleotide KW - Humans KW - Middle Aged KW - Atherosclerosis KW - Black or African American KW - Breast cancer KW - alcohol KW - polygenetic risk score KW - gene-environment interaction KW - risk KW - Aged KW - Female KW - Humans KW - Middle Aged KW - Alcohol Drinking KW - Atherosclerosis KW - Black or African American KW - Breast Neoplasms KW - Follow-Up Studies KW - Genetic Predisposition to Disease KW - Genetic Risk Score KW - Multifactorial Inheritance KW - Polymorphism, Single Nucleotide KW - Postmenopause KW - Prospective Studies KW - Risk Factors KW - White LA - eng PY - 2025 T2 - Cancer Prevention Research (Philadelphia, Pa.) T2 - Cancer Prevention Research (Philadelphia, Pa.), 2025, v. 18, no. 2 TI - Alcohol Consumption Does Not Modify the Polygenic Risk Score-Based Genetic Risk of Breast Cancer in Postmenopausal Women: Atherosclerosis Risk in Communities Study. VL - 18 UR - https://stacks.cdc.gov/view/cdc/261854 ER -
Assessing the Impact of Exposure Misclassification in Case-Control Studies of Self-Reported Medication Use.

Adrien, Nedghie ;

MacLehose, Richard F.

February 2026 | Paediatric and Perinatal Epidemiology, 2026, v. 40, no. 2

Empirically evaluating the potential impact of recall bias on observed associations of prenatal medication exposure is crucial.We sought to assess the effects of exposure misclassification on previous studies of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in early pregnancy and increased risk of amniotic band syndrome (ABS).Using data ...

10/09/2026

Supporting Files

Title : Assessing the Impact of Exposure Misclassification in Case-Control Studies of Self-Reported Medication Use. Personal Author(s) : Adrien, Nedghie;MacLehose, Richard F.;Werler, Martha M.;Yazdy, Mahsa M.;Fox, Matthew P.;Parker, Samantha E.; Corporate Authors(s) : The National Birth Defects Prevention Study Published Date : February 2026 Pages in Document : 190-199 (21 pdf pages) Source : Paediatric and Perinatal Epidemiology, 2026, v. 40, no. 2 DOI : https://doi.org/10.1111/ppe.13161 Journal Title : Paediatric and Perinatal Epidemiology
Adrien, N., MacLehose, R. F., Werler, M. M., Yazdy, M. M., Fox, M. P., & Parker, S. E. (2026). Assessing the Impact of Exposure Misclassification in Case-Control Studies of Self-Reported Medication Use. Paediatric and Perinatal Epidemiology, 40(2). https://doi.org/10.1111/ppe.13161

Adrien, Nedghie, Richard F. MacLehose, Martha M. Werler, Mahsa M. Yazdy, Matthew P. Fox, and Samantha E. Parker. "Assessing the Impact of Exposure Misclassification in Case-Control Studies of Self-Reported Medication Use." Paediatric and Perinatal Epidemiology 40, no. 2 (2026). https://doi.org/10.1111/ppe.13161.

Adrien, Nedghie, et al. "Assessing the Impact of Exposure Misclassification in Case-Control Studies of Self-Reported Medication Use." Paediatric and Perinatal Epidemiology, vol. 40, no. 2, 2026. Stacks. https://doi.org/10.1111/ppe.13161.
Export RIS Citation Information. TY - Journal Article AU - Adrien, Nedghie AU - MacLehose, Richard F. AU - Werler, Martha M. AU - Yazdy, Mahsa M. AU - Fox, Matthew P. AU - Parker, Samantha E. A2 - The National Birth Defects Prevention Study AB - Empirically evaluating the potential impact of recall bias on observed associations of prenatal medication exposure is crucial. AB - We sought to assess the effects of exposure misclassification on previous studies of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in early pregnancy and increased risk of amniotic band syndrome (ABS). AB - Using data from the National Birth Defects Prevention Study (NBDPS) on births from 1997 to 2011, we included 189 mothers of infants with ABS and 11,829 mothers of infants without congenital anomalies. We identified external studies of medication use during pregnancy to obtain validity parameters for a probabilistic bias analysis to adjust for exposure misclassification. Due to uncertainty about the transportability of these parameters, we conducted multidimensional bias analyses to explore combinations of values on the results. AB - When we assumed higher specificity in cases or higher sensitivity in controls, misclassification-adjusted estimates suggested confounding-adjusted estimates were attenuated. However, in a few instances, when we assumed greater sensitivity in the cases than the controls (and Sp ≥ 0.9), the misclassification-adjusted estimates suggested upward bias in the confounding-adjusted estimates. AB - Results from our bias analysis highlighted that the magnitude of bias depended on the mechanism and the extent of misclassification. However, the parameters available from the validation studies were not directly applicable to our study. In the absence of reliable validation studies, considering mechanisms of bias and simulation studies to outline combinations of plausible scenarios to better inform conclusions on the effects of these medications on pregnancy outcomes remains important. AB - Author manuscript AN - cdc:261853 C4 - PMC12167750 DO - https://doi.org/10.1111/ppe.13161 IS - 2 J2 - Paediatric and Perinatal Epidemiology KW - Pregnancy KW - Female KW - Bias KW - Maternal Exposure KW - Case-Control Studies KW - Prenatal Exposure Delayed Effects KW - Humans KW - Infant, Newborn KW - Self Report KW - Adult KW - Anti-Inflammatory Agents, Non-Steroidal KW - Pregnancy Complications KW - epidemiological biases KW - misclassification KW - anti-inflammatory agents KW - non-steroidal KW - congenital abnormalities KW - Humans KW - Female KW - Pregnancy KW - Case-Control Studies KW - Self Report KW - Anti-Inflammatory Agents, Non-Steroidal KW - Bias KW - Adult KW - Infant, Newborn KW - Pregnancy Complications KW - Prenatal Exposure Delayed Effects KW - Maternal Exposure LA - eng PY - 2026 T2 - Paediatric and Perinatal Epidemiology T2 - Paediatric and Perinatal Epidemiology, 2026, v. 40, no. 2 TI - Assessing the Impact of Exposure Misclassification in Case-Control Studies of Self-Reported Medication Use. VL - 40 UR - https://stacks.cdc.gov/view/cdc/261853 ER -
School Nurse Practices Related to Blood Pressure Screening, and Identification and Monitoring of High Blood Pressures in Youth.

Goulding, Melissa ;

Branley, Claire

June 2026 | The Journal of School Nursing: the Official Publication of the National Association of School Nurses, June 2026

Despite rising prevalence of high blood pressure among youth, literature on school nurses' practices related to youth blood pressure is limited. We aimed to describe school nurses' current practices related to blood pressure screening and identification and monitoring of high blood pressures. We conducted a web-based national survey of currently pr ...

10/09/2026

Supporting Files

Title : School Nurse Practices Related to Blood Pressure Screening, and Identification and Monitoring of High Blood Pressures in Youth. Personal Author(s) : Goulding, Melissa;Branley, Claire;O'Brien, Mary Jane;Hayman, Laura L;Lemon, Stephenie C.; Published Date : June 2026 Pages in Document : 10598405241300400 (15 pdf pages) Source : The Journal of School Nursing: the Official Publication of the National Association of School Nurses, June 2026 DOI : https://doi.org/10.1177/10598405241300466 Journal Title : The Journal of School Nursing: the Official Publication of the National Association of School Nurses
Goulding, M., Branley, C., O'Brien, M. J., Hayman, L. L., & Lemon, S. C. (2026). School Nurse Practices Related to Blood Pressure Screening, and Identification and Monitoring of High Blood Pressures in Youth. The Journal of School Nursing: the Official Publication of the National Association of School Nurses. https://doi.org/10.1177/10598405241300466

Goulding, Melissa, Claire Branley, Mary Jane O'Brien, Laura L Hayman, and Stephenie C. Lemon. "School Nurse Practices Related to Blood Pressure Screening, and Identification and Monitoring of High Blood Pressures in Youth." The Journal of School Nursing: the Official Publication of the National Association of School Nurses (2026). https://doi.org/10.1177/10598405241300466.

Goulding, Melissa, et al. "School Nurse Practices Related to Blood Pressure Screening, and Identification and Monitoring of High Blood Pressures in Youth." The Journal of School Nursing: the Official Publication of the National Association of School Nurses, 2026. Stacks. https://doi.org/10.1177/10598405241300466.
Export RIS Citation Information. TY - Journal Article AU - Goulding, Melissa AU - Branley, Claire AU - O'Brien, Mary Jane AU - Hayman, Laura L AU - Lemon, Stephenie C. AB - Despite rising prevalence of high blood pressure among youth, literature on school nurses' practices related to youth blood pressure is limited. We aimed to describe school nurses' current practices related to blood pressure screening and identification and monitoring of high blood pressures. We conducted a web-based national survey of currently practicing school nurses and received 195 responses across 37 states. All participants reported having a blood pressure cuff, nearly all (98%) reported confidence measuring children's blood pressure, and 82% reported interest in doing more to support children's cardiovascular health. Blood pressure measurement by school nurses was common (73% reported "sometimes" or "often" and 25% reported "seldomly"). However, only 32% stated hypertension impacts their students and only 19% endorsed having enough time to complete all their necessary tasks. In describing school nurse's current practices related to youth blood pressure, we highlight opportunities for expanding this role and considerations for doing so. AB - Author manuscript AN - cdc:261852 C4 - PMC12351536 DO - https://doi.org/10.1177/10598405241300466 J2 - The Journal of School Nursing: the Official Publication of the National Association of School Nurses KW - Child KW - Adolescent KW - Surveys and Questionnaires KW - Female KW - School Nursing KW - Mass Screening KW - Practice Patterns, Nurses' KW - Male KW - Hypertension KW - Humans KW - Adult KW - Blood Pressure Determination KW - Humans KW - School Nursing KW - Hypertension KW - Adolescent KW - Blood Pressure Determination KW - Male KW - Female KW - Child KW - Mass Screening KW - Adult KW - Practice Patterns, Nurses' KW - Surveys and Questionnaires LA - eng PY - 2026 T2 - The Journal of School Nursing: the Official Publication of the National Association of School Nurses T2 - The Journal of School Nursing: the Official Publication of the National Association of School Nurses, June 2026 TI - School Nurse Practices Related to Blood Pressure Screening, and Identification and Monitoring of High Blood Pressures in Youth. UR - https://stacks.cdc.gov/view/cdc/261852 ER -
The ETS Domain-containing Hematopoietic Transcription Factor PU.1 Mediates the Induction of Arachidonate 5-lipoxygenase by Multi-walled Carbon Nanotubes in Macrophages in Vitro.

Lim, Chol Seung ;

Gu, Ja Kook

February 2025 | Archives of Toxicology, 2025, v. 99, no. 2

Exposure to fibrogenic multi-walled carbon nanotubes (MWCNTs) induces the production of proinflammatory lipid mediators (LMs) in myeloid cells to instigate inflammation. The molecular underpinnings of LM production in nanotoxicity remain unclear. Here we report that PU.1, an ETS domain-containing master regulator of hematopoiesis, critically regula ...

10/09/2026

Supporting Files

Title : The ETS Domain-containing Hematopoietic Transcription Factor PU.1 Mediates the Induction of Arachidonate 5-lipoxygenase by Multi-walled Carbon Nanotubes in Macrophages in Vitro. Personal Author(s) : Lim, Chol Seung;Gu, Ja Kook;Ma, Qiang; Published Date : February 2025 Pages in Document : 597-610 (26 pdf pages) Source : Archives of Toxicology, 2025, v. 99, no. 2 DOI : https://doi.org/10.1007/s00204-024-03925-w Journal Title : Archives of Toxicology
Lim, C. S., Gu, J. K., & Ma, Q. (2025). The ETS Domain-containing Hematopoietic Transcription Factor PU.1 Mediates the Induction of Arachidonate 5-lipoxygenase by Multi-walled Carbon Nanotubes in Macrophages in Vitro. Archives of Toxicology, 99(2). https://doi.org/10.1007/s00204-024-03925-w

Lim, Chol Seung, Ja Kook Gu, and Qiang Ma. "The ETS Domain-containing Hematopoietic Transcription Factor PU.1 Mediates the Induction of Arachidonate 5-lipoxygenase by Multi-walled Carbon Nanotubes in Macrophages in Vitro." Archives of Toxicology 99, no. 2 (2025). https://doi.org/10.1007/s00204-024-03925-w.

Lim, Chol Seung, et al. "The ETS Domain-containing Hematopoietic Transcription Factor PU.1 Mediates the Induction of Arachidonate 5-lipoxygenase by Multi-walled Carbon Nanotubes in Macrophages in Vitro." Archives of Toxicology, vol. 99, no. 2, 2025. Stacks. https://doi.org/10.1007/s00204-024-03925-w.
Export RIS Citation Information. TY - Journal Article AU - Lim, Chol Seung AU - Gu, Ja Kook AU - Ma, Qiang AB - Exposure to fibrogenic multi-walled carbon nanotubes (MWCNTs) induces the production of proinflammatory lipid mediators (LMs) in myeloid cells to instigate inflammation. The molecular underpinnings of LM production in nanotoxicity remain unclear. Here we report that PU.1, an ETS domain-containing master regulator of hematopoiesis, critically regulates the induction of arachidonate 5-lypoxygenase (Alox5) and the production of LMs. MWCNTs (Mitsui-7) at 2.5 or 10 µg/mL induced the expression of Alox5 in murine and human macrophages at both mRNA and protein levels, accompanied by marked elevation of chemotactic LM leukotriene B4 (LTB4). Induction is comparable to those by potent M1 inducers. Carbon black, an amorphous carbon material control, did not increase Alox5 expression or LTB4 production at equivalent doses. MWCNTs induced the expression of a heterologous luciferase reporter under the control of the murine Alox5 promoter. Deletional analysis of the 2 kb promoter uncovered multiple inhibitory and activating activities. The proximal 250 bp region had the largest activation that was further increased by MWCNTs. The Alox5 promoter contains four PU box-like enhancers. PU.1 bond to each of the enhancers constitutively, which was further increased by MWCNTs. Knockdown of PU.1 using specific small hairpin-RNA blocked the basal and induced expression of Alox5 and the production of LTB4 as well as prostaglandin E2. The results demonstrate a critical role of PU.1 in mediating MWCNTs-induced expression of Alox5 and production of proinflammatory LMs, revealing a molecular framework where the hematopoietic transcription factor PU.1 is activated to orchestrate multiple proinflammatory responses to sterile particulates. AB - Author manuscript AN - cdc:261851 C4 - PMC11852812 DO - https://doi.org/10.1007/s00204-024-03925-w IS - 2 J2 - Archives of Toxicology KW - Trans-Activators KW - Leukotriene B4 KW - Arachidonate 5-Lipoxygenase KW - Animals KW - Proto-Oncogene Proteins KW - Mice, Inbred C57BL KW - Macrophages KW - Nanotubes, Carbon KW - Humans KW - Proto-Oncogene Protein Spi-1 KW - Mice KW - MWCNT KW - PU.1 KW - Alox5 KW - Inflammation KW - Macrophage KW - Nanotubes, Carbon KW - Arachidonate 5-Lipoxygenase KW - Trans-Activators KW - Animals KW - Humans KW - Proto-Oncogene Proteins KW - Macrophages KW - Mice KW - Leukotriene B4 KW - Mice, Inbred C57BL KW - Proto-Oncogene Protein Spi-1 LA - eng PY - 2025 T2 - Archives of Toxicology T2 - Archives of Toxicology, 2025, v. 99, no. 2 TI - The ETS Domain-containing Hematopoietic Transcription Factor PU.1 Mediates the Induction of Arachidonate 5-lipoxygenase by Multi-walled Carbon Nanotubes in Macrophages in Vitro. VL - 99 UR - https://stacks.cdc.gov/view/cdc/261851 ER -
Occupational Injury and Suicide in Washington State, Adjusting For Pre-Injury Depression.

Applebaum, Katie M. ;

Asfaw, Abay

February 2025 | American Journal of Industrial Medicine, 2025, v. 68, no. 2

Occupational injuries have been associated with increased suicide mortality, but prior studies have not accounted for pre-injury depression.We linked injuries that occurred from 1994 to 2000 in the Washington State workers' compensation system with Social Security Administration data on earnings and mortality through 2018. We estimated the subdistr ...

10/09/2026

Supporting Files

Title : Occupational Injury and Suicide in Washington State, Adjusting For Pre-Injury Depression. Personal Author(s) : Applebaum, Katie M.;Asfaw, Abay;O'Leary, Paul K.;Fox, Matthew P.;Tripodis, Yorghos;Busey, Andrew;Gradus, Jaimie L.;Boden, Leslie I.; Published Date : February 2025 Pages in Document : 122-131 (20 pdf pages) Source : American Journal of Industrial Medicine, 2025, v. 68, no. 2 DOI : https://doi.org/10.1002/ajim.23682 Journal Title : American Journal of Industrial Medicine
Applebaum, K. M., Asfaw, A., O'Leary, P. K., Fox, M. P., Tripodis, Y., Busey, A., Gradus, J. L., & Boden, L. I. (2025). Occupational Injury and Suicide in Washington State, Adjusting For Pre-Injury Depression. American Journal of Industrial Medicine, 68(2). https://doi.org/10.1002/ajim.23682

Applebaum, Katie M., Abay Asfaw, Paul K. O'Leary, Matthew P. Fox, Yorghos Tripodis, Andrew Busey, Jaimie L. Gradus, and Leslie I. Boden. "Occupational Injury and Suicide in Washington State, Adjusting For Pre-Injury Depression." American Journal of Industrial Medicine 68, no. 2 (2025). https://doi.org/10.1002/ajim.23682.

Applebaum, Katie M., et al. "Occupational Injury and Suicide in Washington State, Adjusting For Pre-Injury Depression." American Journal of Industrial Medicine, vol. 68, no. 2, 2025. Stacks. https://doi.org/10.1002/ajim.23682.
Export RIS Citation Information. TY - Journal Article AU - Applebaum, Katie M. AU - Asfaw, Abay AU - O'Leary, Paul K. AU - Fox, Matthew P. AU - Tripodis, Yorghos AU - Busey, Andrew AU - Gradus, Jaimie L. AU - Boden, Leslie I. AB - Occupational injuries have been associated with increased suicide mortality, but prior studies have not accounted for pre-injury depression. AB - We linked injuries that occurred from 1994 to 2000 in the Washington State workers' compensation system with Social Security Administration data on earnings and mortality through 2018. We estimated the subdistribution hazard ratio (sHR) and 95% confidence interval using competing risks regression of suicide deaths with lost time compared with medical-only injuries separately for men and women, adjusting for age, pre-injury annual earnings, and industry. We further adjusted for pre-injury diagnosis of major depressive disorder by using a quantitative bias analysis (QBA), with the prevalence of this disorder in workers derived from an external health insurance claims data set. AB - Elevated suicide mortality was observed following lost-time injuries compared with medical-only injuries for men (sHR = 1.49, 95% CI [1.14, 1.93]) and women (sHR = 1.30, 95% CI [1.00, 1.69]), adjusting for age, pre-injury earnings, and industry. Adjusted for pre-injury depression using a QBA, elevated suicide risk in men remained statistically significant (median sHR = 1.33, simulation interval [1.18, 1.47]) but not for women. AB - Workplace injury requiring time off work appeared to remain influential in increasing suicide risk among men, even after controlling for pre-injury depression. The relationship between mental health before and after occupational injury is complex and studies should better integrate mental health pre-injury. AB - Though many questions remain on the complex relationship between work, depression, injuries, and suicide, employers should work to prevent injuries and consider implementing mental health programs, which could be helpful in reducing suicide risk. AB - Author manuscript AN - cdc:261850 C4 - PMC11800232 DO - https://doi.org/10.1002/ajim.23682 IS - 2 J2 - American Journal of Industrial Medicine KW - Workers' Compensation KW - Female KW - Risk Factors KW - Major Depressive Disorder KW - Suicide KW - Prevalence KW - Male KW - Occupational Injuries KW - Humans KW - Middle Aged KW - Young Adult KW - Adult KW - Humans KW - Male KW - Female KW - Occupational Injuries KW - Adult KW - Middle Aged KW - Suicide KW - Workers' Compensation KW - Major Depressive Disorder KW - Risk Factors KW - Young Adult KW - Prevalence LA - eng PY - 2025 T2 - American Journal of Industrial Medicine T2 - American Journal of Industrial Medicine, 2025, v. 68, no. 2 TI - Occupational Injury and Suicide in Washington State, Adjusting For Pre-Injury Depression. VL - 68 UR - https://stacks.cdc.gov/view/cdc/261850 ER -
Shiftwork and Leisure-time Physical Inactivity (LTPI) Among U.S. Workers.

Fekedulegn, Desta ;

Long, D. Leann

January 2025 | Chronobiology International, 2025, v. 42, no. 1

Physical inactivity may exacerbate the adverse health effects associated with shift work. We investigated the association of shift work with leisure-time physical inactivity (LTPI). A cross-sectional analysis included 33 983 adults from National Health Interview Survey who self-reported their work schedule and leisure-time physical activity. Partic ...

10/09/2026

Supporting Files

Title : Shiftwork and Leisure-time Physical Inactivity (LTPI) Among U.S. Workers. Personal Author(s) : Fekedulegn, Desta;Long, D. Leann;Service, Samantha;Gu, Ja K.;Innes, Kim E.; Published Date : January 2025 Pages in Document : 1-13 (23 pdf pages) Source : Chronobiology International, 2025, v. 42, no. 1 DOI : https://doi.org/10.1080/07420528.2024.2437427 Journal Title : Chronobiology International
Fekedulegn, D., Long, D. L., Service, S., Gu, J. K., & Innes, K. E. (2025). Shiftwork and Leisure-time Physical Inactivity (LTPI) Among U.S. Workers. Chronobiology International, 42(1). https://doi.org/10.1080/07420528.2024.2437427

Fekedulegn, Desta, D. Leann Long, Samantha Service, Ja K. Gu, and Kim E. Innes. "Shiftwork and Leisure-time Physical Inactivity (LTPI) Among U.S. Workers." Chronobiology International 42, no. 1 (2025). https://doi.org/10.1080/07420528.2024.2437427.

Fekedulegn, Desta, et al. "Shiftwork and Leisure-time Physical Inactivity (LTPI) Among U.S. Workers." Chronobiology International, vol. 42, no. 1, 2025. Stacks. https://doi.org/10.1080/07420528.2024.2437427.
Export RIS Citation Information. TY - Journal Article AU - Fekedulegn, Desta AU - Long, D. Leann AU - Service, Samantha AU - Gu, Ja K. AU - Innes, Kim E. AB - Physical inactivity may exacerbate the adverse health effects associated with shift work. We investigated the association of shift work with leisure-time physical inactivity (LTPI). A cross-sectional analysis included 33 983 adults from National Health Interview Survey who self-reported their work schedule and leisure-time physical activity. Participants were classified in to two groups as either (a) inactive or (b) insufficiently/sufficiently. Prevalence ratios were derived using SUDAAN. Analyses were stratified by sex. In this sample of U.S. workers, 27% were shift workers, 26% were physically inactive, and 47% did not meet recommended levels of leisure-time physical activity. Inactivity level was 23% higher in women than in men among shift workers but did not differ by sex among daytime workers (PR = 1.02, 95% CI: 0.96-1.07). Evening or night work was associated with higher LTPI among women but not men. LTPI was 17% higher in women working the night shift, and 24% higher in those on the evening shift compared to those working the daytime shift. These findings suggest that shift work may contribute to increased LTPI, with effects that may be particularly pronounced in women. Interventions addressing LTPI among shift workers may help mitigate the adverse health effects that have been linked to shift work in prior studies. AB - Author manuscript AN - cdc:261849 C4 - PMC11835517 DO - https://doi.org/10.1080/07420528.2024.2437427 IS - 1 J2 - Chronobiology International KW - Female KW - Young Adult KW - Motor Activity KW - Cross-Sectional Studies KW - Work Schedule Tolerance KW - Circadian Rhythm KW - Exercise KW - Male KW - Shift Work Schedule KW - Middle Aged KW - Humans KW - Health Surveys KW - Adult KW - Sedentary Behavior KW - Leisure Activities KW - Shift work KW - leisure-time physical inactivity KW - health behavior KW - employment KW - U.S. working adults KW - national survey KW - NHIS KW - sex KW - Humans KW - Female KW - Male KW - Adult KW - Leisure Activities KW - Middle Aged KW - Cross-Sectional Studies KW - Sedentary Behavior KW - Shift Work Schedule KW - Exercise KW - Work Schedule Tolerance KW - Circadian Rhythm KW - Young Adult KW - Motor Activity KW - Health Surveys LA - eng PY - 2025 T2 - Chronobiology International T2 - Chronobiology International, 2025, v. 42, no. 1 TI - Shiftwork and Leisure-time Physical Inactivity (LTPI) Among U.S. Workers. VL - 42 UR - https://stacks.cdc.gov/view/cdc/261849 ER -
A Comment on Metformin in the Diabetes Prevention Program 3-year Trial: the Cost-effectiveness That Never Was .

Herman, William H. ;

Kuo, Shihchen

March 2025 | Diabetes, Obesity & Metabolism, 2025, v. 27, no. 3

Response to the article Rittenhouse BE, Alolayan S, Eguale T, Segal AR, Doucette J. Metformin in the diabetes prevention program 3-year trial: the cost-effectiveness that never was. Diabetes Obes Metab 2024;26:5097-5106. doi:10.1111/dom.15851, the authors defend the methods of their original study.

10/09/2026

Supporting Files

Title : A Comment on Metformin in the Diabetes Prevention Program 3-year Trial: the Cost-effectiveness That Never Was . Personal Author(s) : Herman, William H.;Kuo, Shihchen;Zhang, Ping; Published Date : March 2025 Pages in Document : 1626-1627 (4 pdf pages) Source : Diabetes, Obesity & Metabolism, 2025, v. 27, no. 3 DOI : https://doi.org/10.1111/dom.16124 Journal Title : Diabetes, Obesity & Metabolism
Herman, W. H., Kuo, S., & Zhang, P. (2025). A Comment on Metformin in the Diabetes Prevention Program 3-year Trial: the Cost-effectiveness That Never Was. Diabetes, Obesity & Metabolism, 27(3). https://doi.org/10.1111/dom.16124

Herman, William H., Shihchen Kuo, and Ping Zhang. "A Comment on Metformin in the Diabetes Prevention Program 3-year Trial: the Cost-effectiveness That Never Was." Diabetes, Obesity & Metabolism 27, no. 3 (2025). https://doi.org/10.1111/dom.16124.

Herman, William H., et al. "A Comment on Metformin in the Diabetes Prevention Program 3-year Trial: the Cost-effectiveness That Never Was." Diabetes, Obesity & Metabolism, vol. 27, no. 3, 2025. Stacks. https://doi.org/10.1111/dom.16124.
Export RIS Citation Information. TY - Journal Article AU - Herman, William H. AU - Kuo, Shihchen AU - Zhang, Ping AB - Response to the article Rittenhouse BE, Alolayan S, Eguale T, Segal AR, Doucette J. Metformin in the diabetes prevention program 3-year trial: the cost-effectiveness that never was. Diabetes Obes Metab 2024;26:5097-5106. doi:10.1111/dom.15851, the authors defend the methods of their original study. AB - Author manuscript AN - cdc:261848 C4 - PMC12344529 DO - https://doi.org/10.1111/dom.16124 IS - 3 J2 - Diabetes, Obesity & Metabolism KW - Obesity KW - Metformin KW - Diabetes Mellitus KW - Diabetes Mellitus KW - Metformin KW - Obesity LA - eng PY - 2025 T2 - Diabetes, Obesity & Metabolism T2 - Diabetes, Obesity & Metabolism, 2025, v. 27, no. 3 TI - A Comment on Metformin in the Diabetes Prevention Program 3-year Trial: the Cost-effectiveness That Never Was . VL - 27 UR - https://stacks.cdc.gov/view/cdc/261848 ER -
Malleable and Static Risk Factors Associated With Boys' Patterns of Interpersonal Violence: a Latent Class Analysis.

Rizzo, Andrew J. ;

Scaglione, Nichole M.

December 2025 | Journal of Interpersonal Violence, 2025, v. 40, no. 2324

Despite an increased risk of committing and experiencing violence among adolescent boys, little is known about either how different types of violence co-occur within individuals or their association with different risk factors. This study used a person-centered approach to (1) identify patterns in boys' perpetration and victimization across a range ...

10/09/2026

Supporting Files

Title : Malleable and Static Risk Factors Associated With Boys' Patterns of Interpersonal Violence: a Latent Class Analysis. Personal Author(s) : Rizzo, Andrew J.;Scaglione, Nichole M.;Lowe, Ashley;Kan, Marni L.; Published Date : December 2025 Pages in Document : 5574-5604 (24 pdf pages) Source : Journal of Interpersonal Violence, 2025, v. 40, no. 2324 DOI : https://doi.org/10.1177/08862605241303951 Journal Title : Journal of Interpersonal Violence
Rizzo, A. J., Scaglione, N. M., Lowe, A., & Kan, M. L. (2025). Malleable and Static Risk Factors Associated With Boys' Patterns of Interpersonal Violence: a Latent Class Analysis. Journal of Interpersonal Violence, 40(2324). https://doi.org/10.1177/08862605241303951

Rizzo, Andrew J., Nichole M. Scaglione, Ashley Lowe, and Marni L. Kan. "Malleable and Static Risk Factors Associated With Boys' Patterns of Interpersonal Violence: a Latent Class Analysis." Journal of Interpersonal Violence 40, no. 2324 (2025). https://doi.org/10.1177/08862605241303951.

Rizzo, Andrew J., et al. "Malleable and Static Risk Factors Associated With Boys' Patterns of Interpersonal Violence: a Latent Class Analysis." Journal of Interpersonal Violence, vol. 40, no. 2324, 2025. Stacks. https://doi.org/10.1177/08862605241303951.
Export RIS Citation Information. TY - Journal Article AU - Rizzo, Andrew J. AU - Scaglione, Nichole M. AU - Lowe, Ashley AU - Kan, Marni L. AB - Despite an increased risk of committing and experiencing violence among adolescent boys, little is known about either how different types of violence co-occur within individuals or their association with different risk factors. This study used a person-centered approach to (1) identify patterns in boys' perpetration and victimization across a range of 7 types of interpersonal violence (bullying, electronic aggression, sexual harassment/aggression; and psychological/ physical/sexual dating violence); and (2) examine the association of these patterns with 12 risk factors at the individual, relational, and community level to inform future prevention efforts. We used latent class analysis to identify patterns of violence among a diverse sample of 239 adolescent boys from 12 schools in 4 regions of the United States. Four classes were identified: The LOW-ALL group (36.4% of the sample) described boys unlikely to commit or experience any forms of violence. The PERP-MULTI group (20.9%) included boys with a high probability of committing bullying and sexual harassment and a relatively lower probability of experiencing sexual harassment. The EQUAL-PEER-SH group (33.5%) described boys with a high probability of both committing and experiencing sexual harassment, bullying, and electronic aggression. The smallest group of boys, labeled HIGH-ALL (9.2%), were at a high probability of committing and experiencing nearly all types of violence examined. We used weighted multiple-group analysis to compare risk factors across the latent groups identified. Attitudes supporting violence, internalized traditional masculinity, delinquency, school withdrawal, and both family and community violence exposure were significantly higher in groups with a high likelihood to commit various types of violence. These findings provide practical guidance for enhancing universal and selected violence prevention efforts for adolescent boys. AB - Author manuscript AN - cdc:261847 C4 - PMC12951215 DO - https://doi.org/10.1177/08862605241303951 IS - 2324 J2 - Journal of Interpersonal Violence KW - Adolescent KW - Interpersonal Relations KW - Bullying KW - Crime Victims KW - Sexual Harassment KW - Child KW - Risk Factors KW - Violence KW - Male KW - Humans KW - Intimate Partner Violence KW - Aggression KW - Adolescent Behavior KW - Latent Class Analysis KW - Adolescent boys KW - violence KW - latent class analysis KW - masculinity KW - risk factors KW - Humans KW - Male KW - Risk Factors KW - Adolescent KW - Crime Victims KW - Latent Class Analysis KW - Bullying KW - Aggression KW - Adolescent Behavior KW - Intimate Partner Violence KW - Violence KW - Sexual Harassment KW - Interpersonal Relations KW - Child LA - eng PY - 2025 T2 - Journal of Interpersonal Violence T2 - Journal of Interpersonal Violence, 2025, v. 40, no. 2324 TI - Malleable and Static Risk Factors Associated With Boys' Patterns of Interpersonal Violence: a Latent Class Analysis. VL - 40 UR - https://stacks.cdc.gov/view/cdc/261847 ER -

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