The Use Of Drugs During Pregnancy And Lactation

Details

• Alternative Title:
  Public Health Rep
• Personal Author:
  Berlin, Cheston M.
• Description:
  It is a regulatory fact that only 14 drugs are approved for use during pregnancy; none of them is specifically approved for use in nursing mothers. With the current emphasis on breast feeding, more data describing levels of drugs in fetal blood and drug levels in breast milk are necessary. Some of the pharmacologic properties useful in predicting drug transmission during lactation include lipid solubility, ionization constant, and molecular size (which predisposes a drug to crossing membrane barriers to the fetus and the milk).
• Subjects:
  Breast Feeding Drug-Related Side Effects And Adverse Reactions Drug Approval Female Fetal Blood Humans Infant Infant, Newborn Maternal-Fetal Exchange Milk, Human Pharmacology Pregnancy Prenatal Exposure Delayed Effects

  More +
• Source:
  Public Health Rep. 102(4 Suppl):53-54
• Pubmed ID:
  16156082
• Pubmed Central ID:
  PMCnull
• Document Type:
  Journal Article
• Place as Subject:
  North America
• Volume:
  102
• Collection(s):
  Public Health Reports
• Main Document Checksum:
  urn:sha256:c04c738839054f76c9414d2dbf246cc1e2df42a035b8357c7bd38774a8e30608
• Download URL:
  https://stacks.cdc.gov/view/cdc/63048/cdc_63048_DS1.pdf
• File Type:
  [PDF - 355.90 KB ]