Introductory remarks
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

All these words:

For very narrow results

This exact word or phrase:

When looking for a specific result

Any of these words:

Best used for discovery & interchangable words

None of these words:

Recommended to be used in conjunction with other fields

Language:

Dates

Publication Date Range:

to

Document Data

Title:

Document Type:

Library

Collection:

Series:

People

Author:

Help
Clear All

Query Builder

Query box

Help
Clear All

For additional assistance using the Custom Query please check out our Help Page

i

Introductory remarks

Filetype[PDF-524.02 KB]


  • English

  • Details:

    • Alternative Title:
      Public Health Rep
    • Personal Author:
    • Description:
      The cause of osteoporosis, a condition in which bone mass is decreased to a point where structural failure may occur, is unknown; many factors that contribute to the development of osteoporosis are known.Bone mass increases until the late twenties, the time when people attain peak bone mass. For a time after peak bone mass is reached, bone loss and formation are approximately equal. Soon after that, probably in the early thirties, an uncoupling of bone synthesis and bone resorption occurs, and a net loss of bone mass begins, a process that can ultimately result in osteoporosis.Bone loss occurs most rapidly in white females immediately after menopause. The bone most affected is the spongy, trabecular bone of the vertebrae and pelvis and the ends of long bones.Osteoporosis is classified into two syndromes, which are not distinct but have overlapping features and may have the same pathogenetic mechanism. Type I, or postmenopausal osteoporosis, is associated with estrogen deficiency and is characterized by loss of trabecular bone in the vertebrae and the distal radius (the wrist). Vertebral fractures and wrist fractures (also called Colles' fractures) result. Type II, or senile osteoporosis, is age-related, occurs in men as well as women, and is characterized by fractures of the hip and humerus. There is a loss of cortical as well as trabecular bone.Estrogen deficiency, increasing age, smoking, high alcohol intake, large amounts of caffeine and protein, and lean body mass favor decreased bone density, whereas estrogen replacement after menopause, adequate dietary calcium, and moderate amounts of weight-bearing exercise tend to favor increased bone density.Standard X-rays, computed tomography, single and dual photon absorptiometry, and neutron activation analysis are noninvasive techniques used in evaluating osteoporosis.Calcium, estrogen, and calcitonin are approved drug therapies for osteoporosis.
    • Pubmed ID:
      19313189
    • Pubmed Central ID:
      PMCnull
    • Document Type:
    • Main Document Checksum:
    • File Type:

    Supporting Files

    • No Additional Files

    More +

    Related Documents

    You May Also Like

    Checkout today's featured content at stacks.cdc.gov