Details:

Alternative Title:
Ann Epidemiol
Publisher's site:
http://dx.doi.org/10.1016/j.annepidem.2014.10.004
Personal Author:
Padula, Amy M. ; Mortimer, Kathleen M. ; Tager, Ira B. ; Hammond, S. Katharine ; Lurmann, Frederick W. ; ... More +
Padula, Amy M. ; Mortimer, Kathleen M. ; Tager, Ira B. ; Hammond, S. Katharine ; Lurmann, Frederick W. ; Yang, Wei ; Stevenson, David K. ; Shaw, Gary M. ; Less -
Description:
To evaluate associations between traffic-related air pollution during pregnancy and preterm birth in births in four counties in California during years 2000 to 2006.|We used logistic regression to examine the association between the highest quartile of ambient air pollutants (carbon monoxide, nitrogen dioxide, particulate matter <10 and 2.5 μm) and traffic density during pregnancy and each of five levels of prematurity based on gestational age at birth (20-23, 24-27, 28-31, 32-33, and 34-36 weeks) versus term (37-42 weeks). We examined trimester averages and the last month and the last 6 weeks of pregnancy. Models were adjusted for birthweight, maternal age, race/ethnicity, education, prenatal care, and birth costs payment. Neighborhood socioeconomic status (SES) was evaluated as a potential effect modifier.|There were increased odds ratios (ORs) for early preterm birth for those exposed to the highest quartile of each pollutant during the second trimester and the end of pregnancy (adjusted OR, 1.4-2.8). Associations were stronger among mothers living in low SES neighborhoods (adjusted OR, 2.1-4.3). We observed exposure-response associations for multiple pollutant exposures and early preterm birth. Inverse associations during the first trimester were observed.|The results confirm associations between traffic-related air pollution and prematurity, particularly among very early preterm births and low SES neighborhoods.
Subject:
[+]
Adult
Air Pollutants
Air Pollution
Article
Birth Weight
California
Carbon Monoxide
Female
Gestational Age
Humans
Infant, Newborn
Logistic Models
Male
Maternal Age
Maternal Exposure
Nitrogen Oxides
Particulate Matter
Pregnancy
Pregnancy Outcome
Premature Birth
Preterm Birth
Residence Characteristics
Risk Assessment
Vehicle Emissions
Young Adult
Pregnancy

Source:
Ann Epidemiol. 2014; 24(12):888-95e4
Pubmed ID:
25453347
Pubmed Central ID:
PMC4355392
Document Type:
Journal Article ;
Funding:
6U01DD000489/DD/NCBDD CDC HHS/United States ; K99 ES021470/ES/NIEHS NIH HHS/United States ; R21 ES014891/ES/NIEHS NIH HHS/United States ; K99ES021470/ES/NIEHS NIH HHS/United States ; R21 ESO14891/PHS HHS/United States ; ... More +
6U01DD000489/DD/NCBDD CDC HHS/United States ; K99 ES021470/ES/NIEHS NIH HHS/United States ; R21 ES014891/ES/NIEHS NIH HHS/United States ; K99ES021470/ES/NIEHS NIH HHS/United States ; R21 ESO14891/PHS HHS/United States ; L40 ES023163/ES/NIEHS NIH HHS/United States ; P01 ES022849/ES/NIEHS NIH HHS/United States ; P20 ES018173/ES/NIEHS NIH HHS/United States ; P20ES018173/ES/NIEHS NIH HHS/United States ; P01ES022849/ES/NIEHS NIH HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d2388a688ef0deb8fd03d84cbaced48093820a128032c9151cf45654c79a08e2
File Type:

Supporting Files

• 	NIHMS640759-supplement-1.docx	docx
  	NIHMS640759-supplement-2.docx	docx
  	NIHMS640759-supplement-3.docx	docx
  	NIHMS640759-supplement-4.docx	docx
  	NIHMS640759-supplement-5.docx	docx
  	NIHMS640759-supplement-6.docx	docx
  	NIHMS640759-supplement-7.docx	docx
  	nihms640759.nxml	xml

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