Traffic-Related Air Pollution and Risk of Preterm Birth in the San Joaquin Valley of California

Padula, Amy M.; Mortimer, Kathleen M.; Tager, Ira B.; Hammond, S. Katharine; Lurmann, Frederick W.; Yang, Wei; Stevenson, David K.; Shaw, Gary M.

doi:10.1016/j.annepidem.2014.10.004

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Traffic-Related Air Pollution and Risk of Preterm Birth in the San Joaquin Valley of California

Published Date:

Dec 2014

Publisher's site:

http://dx.doi.org/10.1016/j.annepidem.2014.10.004

Source:

Ann Epidemiol. 2014; 24(12):888-95e4

Language:

English

[PDF-574.71 KB]

Details:

Alternative Title:

Ann Epidemiol

Personal Author:

Padula, Amy M. ; Mortimer, Kathleen M. ; Tager, Ira B. ; Hammond, S. Katharine ; Lurmann, Frederick W. ; ... More ▼

Description:

To evaluate associations between traffic-related air pollution during pregnancy and preterm birth in births in four counties in California during years 2000 to 2006.|We used logistic regression to examine the association between the highest quartile of ambient air pollutants (carbon monoxide, nitrogen dioxide, particulate matter <10 and 2.5 μm) and traffic density during pregnancy and each of five levels of prematurity based on gestational age at birth (20-23, 24-27, 28-31, 32-33, and 34-36 weeks) versus term (37-42 weeks). We examined trimester averages and the last month and the last 6 weeks of pregnancy. Models were adjusted for birthweight, maternal age, race/ethnicity, education, prenatal care, and birth costs payment. Neighborhood socioeconomic status (SES) was evaluated as a potential effect modifier.|There were increased odds ratios (ORs) for early preterm birth for those exposed to the highest quartile of each pollutant during the second trimester and the end of pregnancy (adjusted OR, 1.4-2.8). Associations were stronger among mothers living in low SES neighborhoods (adjusted OR, 2.1-4.3). We observed exposure-response associations for multiple pollutant exposures and early preterm birth. Inverse associations during the first trimester were observed.|The results confirm associations between traffic-related air pollution and prematurity, particularly among very early preterm births and low SES neighborhoods.

Subject:

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Pubmed ID:

25453347

Pubmed Central ID:

PMC4355392

Document Type:

Journal Article

Funding:

6U01DD000489/DD/NCBDD CDC HHS/United States ; K99 ES021470/ES/NIEHS NIH HHS/United States ; R21 ES014891/ES/NIEHS NIH HHS/United States ; K99ES021470/ES/NIEHS NIH HHS/United States ; R21 ESO14891/PHS HHS/United States ; ... More ▼

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