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Showing 44241 - 44260 of 82803 results
  • Induction of Apoptosis from Instillation of Agricultural Dust
    Induction of Apoptosis from Instillation of Agricultural Dust
    Antonini JM ;
    Castranova, Vincent
    2002/03/22 | National Institute for Occupational Safety and Health (NIOSH)
    In this study, we test the hypothesis that induction of alveolar macrophages (AM) apoptosis plays a role in lung injury from particulates. We examined AM apoptosis in F344 rats following intratracheal instillation of 1ml of saline containing 4mg of particles. Particles used include crystalline silica, titanium dioxide and particulates from air samp ...
    Public Domain
  • Alternation of Innate and CellMediated Immunity to Listeria monocytogenes by ShortTerm Exposure to Diesel Exhaust Particles
    Alternation of Innate and Cell-Mediated Immunity to Listeria monocytogenes by Short-Term Exposure to Diesel Exhaust Particles
    Antonini JM ;
    Barger MW
    2002/03/22 | National Institute for Occupational Safety and Health (NIOSH)
    The effects of diesel exhaust particles (DEP) on functions of pulmonary host defense were studied using a rat Listeria infection model. Short-term DEP inhalation (50 and 100 mg/m3, 4 h) by rats resulted in a slowed lung bacterial clearance, suppressed alveolar macrophage (AM) phagocytosis and reduced AM production of tumor necrosis factor (TNF)-alp ...
    Public Domain
  • Comparison of the Responsiveness of Primary Alveolar Macrophages AMs Primary Alveolar Type II Cells TII and a Rat Alveolar Type II Cell Line RLE6TN to Lipopolysaccharide LPS and Silica Exposure
    Comparison of the Responsiveness of Primary Alveolar Macrophages (AM’s), Primary Alveolar Type II Cells (TII), and a Rat Alveolar Type II Cell Line (RLE-6TN) to Lipopolysaccharide (LPS) and Silica Exposure
    Castranova, Vincent ;
    Kang J
    2002/03/22 | National Institute for Occupational Safety and Health (NIOSH)
    The goal of this study was to compare the responses of AM's and TII cells' to LPS or silica and eventually determine their mutual interactions. AM's were collected by bronchoalveolar lavage, TII cells were isolated by enzymatic digestion and purified by panning (approximately 20 million cells/rat, 95% pure), and RLE-6TN were commercially obtained. ...
    Public Domain
  • Phosphoinositide 3Kinase Activity Leads to NFkB Activation Through Interacting with TyrosinePhosphorylated IkBA and Contributing to Tyrosine Phosphorylation of p65 NFkB
    Phosphoinositide 3-Kinase Activity Leads to NF-kB Activation Through Interacting with Tyrosine-Phosphorylated IkB-A and Contributing to Tyrosine Phosphorylation of p65 NF-kB
    Castranova, Vincent ;
    Kang JL
    2002/03/22 | National Institute for Occupational Safety and Health (NIOSH)
    The role and mechanisms of PI3-kinase activity in NF-kB activation in silica-stimulated RAW 264.7 cells were investigated. Results indicate that the p85a subunit of PI3-kinase interacted with tyrosine-phosphorylated IkB-a in silica-stimulated cells. PI3-kinase specific inhibitors, such as wortmannin and LY294003, substantially blocked both silica-i ...
    Public Domain
  • Ventilation Control to Reduce Airborne Contaminants
    Ventilation Control to Reduce Airborne Contaminants
    Donham KJ ;
    Hoff SJ
    2002/03/21 | Grant Final Reports
    Studies have shown conclusively that airborne contaminant levels in swine confinements are typically of a sufficient level to pose a health hazard to workers in that occupation. In addition to a particulate component that can reach levels of 26 mg/m3, gases present in confinements in high amounts include methane, hydrogen sulfide, ammonia, and carb ...
  • Career Fire Fighter Dies After Becoming Trapped by Fire in Apartment Building New Jersey
    Career Fire Fighter Dies After Becoming Trapped by Fire in Apartment Building – New Jersey
    McFall, Mark F. ;
    Cortez, Kimberly L.
    2002/03/21 | Fire Fighter Fatality Investigation and Prevention Program (FFFIPP)
    Death in the Line of Duty…a Summary of a NIOSH Fire Fighter Fatality InvestigationOn May 9, 2001, a 40-year-old male career fire fighter (the victim) died after he became trapped in a third-floor apartment while searching above the fire for occupants. The victim and Fire Fighter #1, from Truck 2, were assigned to conduct a primary search for a moth ...
    Public Domain
  • Respirator Use and Practices
    Respirator Use and Practices
    Kyriazi, Nicholas ;
    Shubilla, John P.
    2002/03/20 | National Institute for Occupational Safety and Health (NIOSH)
    Respirators had been used by employees in about 10 percent of the private industry workplaces surveyed in late 2001. In nearly half of these 619,400 establishments where respirators were used, they were used by employees on a voluntary basis only, and, in about 12 percent, they were used only when required because of emergencies (table 1). These da ...
    Public Domain
  • Arsenite Modulation of the Integrity of Actin Filaments and the Increase in Cell Motility May Be Mediated Through CDC42
    Arsenite Modulation of the Integrity of Actin Filaments and the Increase in Cell Motility May Be Mediated Through CDC42
    Flynn DC ;
    Qian Y
    2002/03/20 | National Institute for Occupational Safety and Health (NIOSH)
    Arsenite is a human carcinogen, however, the molecular mechanisms involved are poorly understood. By stimulating human endothelial cells (SVEC4-10) with arsenite, we found that arsenite modulated the integrity of actin filaments, and stimulated the formation of cell motility organelle structures within 5 minutes. Further, we found arsenite increase ...
    Public Domain
  • Construction Worker Caught Between Forklift and Cement Truck
    Construction Worker Caught Between Forklift and Cement Truck
    Davis, Arthur W. ;
    Hetzler, William E.
    2002/03/19 | Fatality Assessment and Control Evaluation Reports (FACE)
    A 71-year-old construction worker was killed when the forklift he had been operating rolled forward, pinning him against the rear of a cement truck. The victim had gone to the local redi-mix concrete company earlier that morning and had driven the full concrete truck to the job location. He positioned it in an alleyway behind and adjacent to the wo ...
  • 36YearOld Paper Factory Worker Dies From Crushing Injuries After Being Caught in a Horizontal Baler Pennsylvania
    36-Year-Old Paper Factory Worker Dies From Crushing Injuries After Being Caught in a Horizontal Baler - Pennsylvania
    National Institute for Occupational Safety and Health. Fatality Assessment and Control Evaluation (FACE) Program
    2002/03/14 | Fatality Assessment and Control Evaluation Reports (FACE)
    A 36-year-old male paper factory worker (the victim) died from crushing injuries after being caught by the ram inside a 2-stage horizontal baling machine (Figure 1). The victim, working alone in the warehouse area of a paper plant, was compacting wastepaper when at some point in the compacting process he entered (either intentionally or advertently ...
    Public Domain
  • Fire Fighter Suffers Fatal Heart Attack After Returning Home from Fire Iowa
    Fire Fighter Suffers Fatal Heart Attack After Returning Home from Fire – Iowa
    Singal, Mitchell
    2002/03/13 | Fire Fighter Fatality Investigation and Prevention Program (FFFIPP)
    Death in the Line of Duty…a Summary of a NIOSH Fire Fighter Fatality InvestigationOn April 2, 2001, a 38-year-old male volunteer fire fighter was driving to work after returning home from a structural fire. He apparently passed out at an intersection, and his vehicle rolled across the road and into a fence. Police arrived approximately 3 minutes la ...
    Public Domain
  • 28yearold Laborer Dies After Being Struck by Excavator Bucket North Carolina
    28-year-old Laborer Dies After Being Struck by Excavator Bucket - North Carolina
    National Institute for Occupational Safety and Health. Fatality Assessment and Control Evaluation (FACE) Program
    2002/03/13 | Fatality Assessment and Control Evaluation Reports (FACE)
    On March 12, 2001, a 28-year-old laborer (the victim) died after he was struck by the bucket of a hydraulic excavator. The victim, a coworker, and the company president were using an excavator equipped with a quick-disconnect bucket-coupler to load concrete manhole sections onto a truck for transport to another location. The company president was o ...
    Public Domain
  • Fire Fighter Suffers a Fatal Heart Attack During a Training Exercise Michigan
    Fire Fighter Suffers a Fatal Heart Attack During a Training Exercise – Michigan
    Singal, Mitchell
    2002/03/13 | Fire Fighter Fatality Investigation and Prevention Program (FFFIPP)
    Death in the Line of Duty…a Summary of a NIOSH Fire Fighter Fatality InvestigationOn April 23, 2001, a 58-year-old male volunteer fire fighter participated in a search-and-rescue training exercise. Wearing full turnout gear, including self contained breathing apparatus (SCBA) with a black cover on the face piece (to stimulate impaired visibility), ...
    Public Domain
  • Three Ironworkers Die After Heavylift Crane Tips OverWisconsin
    Three Ironworkers Die After Heavy-lift Crane Tips Over-Wisconsin
    National Institute for Occupational Safety and Health. Fatality Assessment and Control Evaluation (FACE) Program
    2002/03/13 | Fatality Assessment and Control Evaluation Reports (FACE)
    On July 14, 1999, three male ironworkers (the victims), ages 39, 40, and 52, died after falling approximately 300 feet to the ground when the suspended personnel platform they were occupying was struck by the uncontrolled load of a heavy-lift crane. The victims were working in windy conditions during the construction of a county sports stadium. The ...
    Public Domain
  • Fifteen YearOld Laborer Dies After Falling Through a SkylightFlorida
    Fifteen -Year-Old Laborer Dies After Falling Through a Skylight—Florida
    National Institute for Occupational Safety and Health. Fatality Assessment and Control Evaluation (FACE) Program
    2002/03/08 | Fatality Assessment and Control Evaluation Reports (FACE)
    On January 17, 2001, a 15-year-old male laborer (the victim) died from injuries he sustained when he fell through a skylight to the lower ground level approximately 23 feet, 9 inches below. The company's president allowed the company's handyman to find someone to help him repair leaks in a flat roof over the company's three-sided warehouse. The han ...
    Public Domain
  • Truck Driver Killed In Highway Work Zone Collision
    Truck Driver Killed In Highway Work Zone Collision
    Bost, Patrick ;
    Bresnitz, Eddy A.
    2002/03/07 | Fatality Assessment and Control Evaluation Reports (FACE)
    On March 12, 2001, a 52-year-old truck driver was killed when his tractor-trailer truck struck a dump truck protecting a highway work zone. The incident occurred on a major interstate highway as the victim was hauling a container of municipal waste to a landfill. A state road crew was working that morning to fill potholes in the right-hand lane of ...
  • Laborer Killed When a Truck Struck a Backhoe and Pinned the Victim Between the Backhoe and a Dumpster
    Laborer Killed When a Truck Struck a Backhoe and Pinned the Victim Between the Backhoe and a Dumpster
    Bost, Patrick ;
    Bresnitz, Eddy A.
    2002/03/06 | Fatality Assessment and Control Evaluation Reports (FACE)
    On December 15, 2000, the driver of a trash-container truck, returning to the employer's building at the end of his workday, drove the truck onto a service road located between a building and railroad track. Driving around obstacles in the road, the driver steered the truck too close to a passing freight train. The truck was struck by the train and ...
  • Temporary Service Worker Dies After Mower Rolls Over on Him North Carolina
    Temporary Service Worker Dies After Mower Rolls Over on Him - North Carolina
    National Institute for Occupational Safety and Health. Fatality Assessment and Control Evaluation (FACE) Program
    2002/03/05 | Fatality Assessment and Control Evaluation Reports (FACE)
    A 43-year-old male temporary service worker (the victim) died after the mower he was operating rolled over on top of him as he was mowing up a bank. The victim was a member of a five-person crew performing maintenance at an interstate highway rest stop. While the victim mowed the grass on the rest stop grounds, the crew leader and two coworkers cle ...
    Public Domain
  • FourteenYearOld Laborer Dies After a Stored Piece of Hoisting Apparatus Fell on Him at an Automobile Repossession YardPennsylvania
    Fourteen-Year-Old Laborer Dies After a Stored Piece of Hoisting Apparatus Fell on Him at an Automobile Repossession Yard-Pennsylvania
    National Institute for Occupational Safety and Health. Fatality Assessment and Control Evaluation (FACE) Program
    2002/03/05 | Fatality Assessment and Control Evaluation Reports (FACE)
    A 14-year-old male laborer (the victim) died of crushing injuries after a damaged portion of hoisting apparatus (illusion unit) at an automobile repossession yard fell on him. The youth had been hired to pull weeds and perform general clean-up around the perimeter of the yard and the buildings located within the yard. At the time of the incident, t ...
    Public Domain
  • Trabajador temporal pierde la vida al volcarse sobre l una podadora de csped Carolina del Norte
    Trabajador temporal pierde la vida al volcarse sobre él una podadora de césped - Carolina del Norte.
    Casini, Virgil J.
    2002/03/05 | Fatality Assessment and Control Evaluation Reports (FACE)
    Un trabajador temporal de 43 años y sexo masculino (la víctima), quien se encontraba podando el césped en un terraplén, pierdió la vida cuando la podadora se volcó sobre él. La víctima formaba parte de una cuadrilla de cinco personas que hacía trabajos de mantenimiento en un área de descanso vial, en una autopista interestatal. Mientras la víctima ...
    Public Domain
44241 - 44260 / 82803