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Showing 1681 - 1700 of 1966 results

Telework and worker health and well-being: a review and recommendations for research and practice.

Beckel JLO ;

Fisher, Gwenith G.

2022/04/01 | National Institute for Occupational Safety and Health (NIOSH)

Telework (also referred to as telecommuting or remote work), is defined as working outside of the conventional office setting, such as within one's home or in a remote office location, often using a form of information communication technology to communicate with others (supervisors, coworkers, subordinates, customers, etc.) and to perform work tas ...

12/01/2025

Title : Telework and worker health and well-being: a review and recommendations for research and practice. Personal Author(s) : Beckel JLO;Fisher, Gwenith G.; Published Date : 2022/04/01 URL : https://stacks.cdc.gov/view/cdc/249291 Beckel JLO and Fisher, Gwenith G. (2022). Telework and worker health and well-being: a review and recommendations for research and practice.. 19(7). Beckel JLO and Fisher, Gwenith G. "Telework and worker health and well-being: a review and recommendations for research and practice." 19, no. 7 (2022) Beckel JLO and Fisher, Gwenith G. "Telework and worker health and well-being: a review and recommendations for research and practice." vol. 19, no. 7, 2022 Export RIS Citation Information. TY - Journal Article AU - Beckel JLO AU - Fisher, Gwenith G. AB - Telework (also referred to as telecommuting or remote work), is defined as working outside of the conventional office setting, such as within one's home or in a remote office location, often using a form of information communication technology to communicate with others (supervisors, coworkers, subordinates, customers, etc.) and to perform work tasks. Remote work increased over the last decade and tremendously in response to the COVID-19 pandemic. The purpose of this article is to review and critically evaluate the existing research about telework and worker health and well-being. In addition, we review and evaluate how engaging in this flexible form of work impacts worker health and well-being. Specifically, we performed a literature search on the empirical literature related to teleworking and worker health and well-being, and reviewed articles published after the year 2000 based on the extent to which they had been discussed in prior reviews. Next, we developed a conceptual framework based on our review of the empirical literature. Our model explains the process by which telework may affect worker health and well-being in reference to individual, work/life/family, organizational, and macro level factors. These components are explained in depth, followed by methodological and fundamental recommendations intended to guide future research, policies, and practices to maximize the benefits and minimize the harms associated with telework, and offer recommendations for future research. [Description provided by NIOSH] AN - cdc:249291 IS - 7 KW - Occupational Health KW - Safety KW - Workplace KW - Workers; Work environment; Worker health; Communication systems; Task performance; Models; Work-life balance; KW - Author Keywords: flexible work arrangements; remote work; telework; worker health; worker well-being KW - Occupational Health KW - Safety KW - Workplace LA - eng PY - 2022/04/01 TI - Telework and worker health and well-being: a review and recommendations for research and practice. VL - 19 UR - https://stacks.cdc.gov/view/cdc/249291 ER -
The short form effort-reward imbalance: measure of occupational stress for firefighters.

Chin DL ;

Hong O

2022/06/01 | National Institute for Occupational Safety and Health (NIOSH)

Purpose: The original effort-reward imbalance (ERI) questionnaire has been widely used as a measure of occupational stress. The need for brief measurement of psychosocial stress at work has risen. This study examined the psychometric properties of a 16-item short form ERI (S-ERI) questionnaire. Methods: A cross-sectional study was conducted with a ...

12/01/2025

Title : The short form effort-reward imbalance: measure of occupational stress for firefighters. Personal Author(s) : Chin DL;Hong O;Kyung M;Li J;Phelps S; Published Date : 2022/06/01 Pages in Document : 492-499 URL : https://stacks.cdc.gov/view/cdc/249290 Chin DL et al. (2022). The short form effort-reward imbalance: measure of occupational stress for firefighters.. 65(6). Chin DL et al. "The short form effort-reward imbalance: measure of occupational stress for firefighters." 65, no. 6 (2022) Chin DL et al. "The short form effort-reward imbalance: measure of occupational stress for firefighters." vol. 65, no. 6, 2022 Export RIS Citation Information. TY - Journal Article AU - Chin DL AU - Hong O AU - Kyung M AU - Li J AU - Phelps S AB - Purpose: The original effort-reward imbalance (ERI) questionnaire has been widely used as a measure of occupational stress. The need for brief measurement of psychosocial stress at work has risen. This study examined the psychometric properties of a 16-item short form ERI (S-ERI) questionnaire. Methods: A cross-sectional study was conducted with a convenience sample of 247 career firefighters in the United States. An internet-based survey contained the S-ERI questionnaire, and assessed perceived health, demographics, and work characteristics. Internal consistency was tested by item-total correlation and Cronbach's alpha coefficients. Factorial validity was assessed by confirmatory factor analysis (CFA), and criterion validity was examined by testing the S-ERI's association with perceived health, controlling for other factors. Results: The study participants were primarily young and mid-aged White males (mean age = 42 years, 75% White non-Hispanic, 93% males). The S-ERI questionnaire showed satisfactory internal consistency, with Cronbach a coefficients above 0.80 for all three scales: effort 0.82, reward 0.83, and overcommitment 0.81. CFA showed all the S-ERI components had a good fit (goodness-of-fit index = 0.99, comparative fit index = 0.92, root mean square error of approximation = 0.06). In terms of criterion validity, significantly increased odds ratios (ORs) for perceived health (those indicating they were less healthy) were found in firefighters in the lowest tertile of reward (OR = 7.06, 95% confidence interval [CI]: 2.86-17.43), and highest tertile of overcommitment (OR = 2.29, 95% CI: 1.00-5.22), after controlling for other factors. Conclusion: The S-ERI questionnaire is a reliable and valid measure to assess occupational stress. We recommend the use of S-ERI as a measure of occupational stress when initiating efforts to improve firefighters' wellness. [Description provided by NIOSH] AN - cdc:249290 IS - 6 KW - Demography KW - Firefighters KW - Occupational Health KW - Safety KW - Surveys and Questionnaires KW - Workplace KW - Fire fighters; Stress; Questionnaires; Psychosocial factors; Work environment; Worker health; Demographic characteristics; KW - Author Keywords: effort-reward imbalance; firefighter; occupational stress; psychometric properties KW - Demography KW - Firefighters KW - Occupational Health KW - Safety KW - Surveys and Questionnaires KW - Workplace LA - eng PY - 2022/06/01 TI - The short form effort-reward imbalance: measure of occupational stress for firefighters. VL - 65 UR - https://stacks.cdc.gov/view/cdc/249290 ER -
Pathology and mineralogy demonstrate respirable crystalline silica is a major cause of severe pneumoconiosis in U.S. coal miners.

Abraham JL ;

Almberg KS

2022/09/01 | National Institute for Occupational Safety and Health (NIOSH)

Rationale: The reasons for resurgent coal workers' pneumoconiosis and its most severe forms, rapidly progressive pneumoconiosis and progressive massive fibrosis (PMF), in the United States are not yet fully understood. Objectives: To compare the pathologic and mineralogic features of contemporary coal miners with severe pneumoconiosis with those of ...

12/01/2025

Title : Pathology and mineralogy demonstrate respirable crystalline silica is a major cause of severe pneumoconiosis in U.S. coal miners. Personal Author(s) : Abraham JL;Almberg KS;Clingerman SM;Cohen RA;Cool CD;Franko AD;Go LHT;Green FHY;Hubbs, Ann F.;Iwaniuk C;Lowers HA;Murray J;Orandle MS;Petsonk, Edward L.;Richardson DL;Rose CS;Sanyal S;Sarver EA;Vorajee NI;Zell-Baran LM;Zulfikar R; Published Date : 2022/09/01 URL : https://stacks.cdc.gov/view/cdc/249289 Abraham JL et al. (2022). Pathology and mineralogy demonstrate respirable crystalline silica is a major cause of severe pneumoconiosis in U.S. coal miners.. 19(9). Abraham JL et al. "Pathology and mineralogy demonstrate respirable crystalline silica is a major cause of severe pneumoconiosis in U.S. coal miners." 19, no. 9 (2022) Abraham JL et al. "Pathology and mineralogy demonstrate respirable crystalline silica is a major cause of severe pneumoconiosis in U.S. coal miners." vol. 19, no. 9, 2022 Export RIS Citation Information. TY - Journal Article AU - Abraham JL AU - Almberg KS AU - Clingerman SM AU - Cohen RA AU - Cool CD AU - Franko AD AU - Go LHT AU - Green FHY AU - Hubbs, Ann F. AU - Iwaniuk C AU - Lowers HA AU - Murray J AU - Orandle MS AU - Petsonk, Edward L. AU - Richardson DL AU - Rose CS AU - Sanyal S AU - Sarver EA AU - Vorajee NI AU - Zell-Baran LM AU - Zulfikar R AB - Rationale: The reasons for resurgent coal workers' pneumoconiosis and its most severe forms, rapidly progressive pneumoconiosis and progressive massive fibrosis (PMF), in the United States are not yet fully understood. Objectives: To compare the pathologic and mineralogic features of contemporary coal miners with severe pneumoconiosis with those of their historical counterparts. Methods: Lung pathology specimens from 85 coal miners with PMF were included for evaluation and analysis. We compared the proportion of cases with pathologic and mineralogic findings in miners born between 1910 and 1930 (historical) with those in miners born in or after 1930 (contemporary). Results: We found a significantly higher proportion of silica-type PMF (57% vs. 18%; P < 0.001) among contemporary miners compared with their historical counterparts. Mineral dust alveolar proteinosis was also more common in contemporary miners compared with their historical counterparts (70% vs. 37%; P < 0.01). In situ mineralogic analysis showed that the percentage (26.1% vs. 17.8%; P < 0.01) and concentration (47.3 × 108 vs. 25.8 × 108 particles/cm3; P = 0.036) of silica particles were significantly greater in specimens from contemporary miners compared with their historical counterparts. The concentration of silica particles was significantly greater when silica-type PMF, mineral dust alveolar proteinosis, silicotic nodules, or immature silicotic nodules were present (P < 0.05). Conclusions: Exposure to respirable crystalline silica appears causal in the unexpected surge of severe disease in contemporary miners. Our findings underscore the importance of controlling workplace silica exposure to prevent the disabling and untreatable adverse health effects afflicting U.S. coal miners. [Description provided by NIOSH] AN - cdc:249289 IS - 9 KW - Coal KW - Coal Mining KW - Fibrosis KW - Lung KW - Lung Diseases KW - Mining KW - Occupational Health KW - Pathology KW - Respiratory System KW - Respiratory Tract Diseases KW - Safety KW - Silicon Dioxide KW - Silicosis KW - Pathology; Crystalline silica; Coal workers pneumoconiosis; Black lung disease; Coal miners; Coal mines; Coal mining; Fibrosis; KW - Author Keywords: silicosis; coal workers; dust KW - Coal KW - Coal Mining KW - Fibrosis KW - Lung KW - Lung Diseases KW - Mining KW - Occupational Health KW - Pathology KW - Respiratory System KW - Respiratory Tract Diseases KW - Safety KW - Silicon Dioxide KW - Silicosis LA - eng PY - 2022/09/01 TI - Pathology and mineralogy demonstrate respirable crystalline silica is a major cause of severe pneumoconiosis in U.S. coal miners. VL - 19 UR - https://stacks.cdc.gov/view/cdc/249289 ER -
The impact of oil spill to lung health - insights from an RNA-seq study of human airway epithelial cells.

Baddoo MC ;

Flemington EK

2016/03/01 | National Institute for Occupational Safety and Health (NIOSH)

The Deepwater Horizon oil spill (BP oil spill) in the Gulf of Mexico was a unique disaster event, where a huge amount of oil spilled from the sea bed and a large volume of dispersants were applied to clean the spill. The operation lasted for almost 3 months and involved > 50,000 workers. The potential health hazards to these workers may be signific ...

12/01/2025

Title : The impact of oil spill to lung health - insights from an RNA-seq study of human airway epithelial cells. Personal Author(s) : Baddoo MC;Flemington EK;Liu Y-Z;Roy-Engel AM;Wang G;Wang H; Published Date : 2016/03/01 Pages in Document : 38-51 URL : https://stacks.cdc.gov/view/cdc/249288 Baddoo MC et al. (2016). The impact of oil spill to lung health - insights from an RNA-seq study of human airway epithelial cells.. 578(1). Baddoo MC et al. "The impact of oil spill to lung health - insights from an RNA-seq study of human airway epithelial cells." 578, no. 1 (2016) Baddoo MC et al. "The impact of oil spill to lung health - insights from an RNA-seq study of human airway epithelial cells." vol. 578, no. 1, 2016 Export RIS Citation Information. TY - Journal Article AU - Baddoo MC AU - Flemington EK AU - Liu Y-Z AU - Roy-Engel AM AU - Wang G AU - Wang H AB - The Deepwater Horizon oil spill (BP oil spill) in the Gulf of Mexico was a unique disaster event, where a huge amount of oil spilled from the sea bed and a large volume of dispersants were applied to clean the spill. The operation lasted for almost 3 months and involved > 50,000 workers. The potential health hazards to these workers may be significant as previous research suggested an association of persistent respiratory symptoms with exposure to oil and oil dispersants. To reveal the potential effects of oil and oil dispersants on the respiratory system at the molecular level, we evaluated the transcriptomic profile of human airway epithelial cells grown under treatment of crude oil, the dispersants Corexit 9500 and Corexit 9527, and oil-dispersant mixtures. We identified a very strong effect of Corexit 9500 treatment, with 84 genes (response genes) differentially expressed in treatment vs. control samples. We discovered an interactive effect of oil-dispersant mixtures; while no response gene was found for Corexit 9527 treatment alone, cells treated with Corexit 9527 + oil mixture showed an increased number of response genes (46 response genes), suggesting a synergic effect of 9527 with oil on airway epithelial cells. Through GO (gene ontology) functional term and pathway-based analysis, we identified upregulation of gene sets involved in angiogenesis and immune responses and downregulation of gene sets involved in cell junctions and steroid synthesis as the prevailing transcriptomic signatures in the cells treated with Corexit 9500, oil, or Corexit 9500 + oil mixture. Interestingly, these key molecular signatures coincide with important pathological features observed in common lung diseases, such as asthma, cystic fibrosis and chronic obstructive pulmonary disease. Our study provides mechanistic insights into the detrimental effects of oil and oil dispersants to the respiratory system and suggests significant health impacts of the recent BP oil spill to those people involved in the cleaning operation. [Description provided by NIOSH] AN - cdc:249288 IS - 1 KW - Genetics KW - Lung Diseases KW - Occupational Health KW - Oil and Gas Industry KW - Respiratory System KW - Respiratory Tract Diseases KW - Safety KW - Oil industry; Oil spills; Spill cleanup; Respiratory diseases; Lung disease; Airway resistance; Molecular epidemiology; Genes; Gene expression; Disaster clean-up; KW - Author Keywords: BP oil spill; oil dispersants; RNA-seq; lung health; airway epithelial cells KW - Genetics KW - Lung Diseases KW - Occupational Health KW - Oil and Gas Industry KW - Respiratory System KW - Respiratory Tract Diseases KW - Safety LA - eng PY - 2016/03/01 TI - The impact of oil spill to lung health - insights from an RNA-seq study of human airway epithelial cells. VL - 578 UR - https://stacks.cdc.gov/view/cdc/249288 ER -
Exposure group development in support of the NIEHS GuLF Study.

Banerjee S ;

Blair, Austin

2022/04/01 | National Institute for Occupational Safety and Health (NIOSH)

In the GuLF Study, a study investigating possible adverse health effects associated with work on the oil spill response and clean-up (OSRC) following the Deepwater Horizon disaster in the Gulf of Mexico, we used a job-exposure matrix (JEM) approach to estimate exposures. The JEM linked interview responses of study participants to measurement data t ...

12/01/2025

Title : Exposure group development in support of the NIEHS GuLF Study. Personal Author(s) : Banerjee S;Blair, Austin;Engel LS;Groth CP;Huynh TB;Kwok RK;Ramachandran G;Sandler DP;Stenzel MR;Stewart PA; Published Date : 2022/04/01 URL : https://stacks.cdc.gov/view/cdc/249287 Banerjee S et al. (2022). Exposure group development in support of the NIEHS GuLF Study.. 66 Banerjee S et al. "Exposure group development in support of the NIEHS GuLF Study." 66 (2022) Banerjee S et al. "Exposure group development in support of the NIEHS GuLF Study." vol. 66, 2022 Export RIS Citation Information. TY - Journal Article AU - Banerjee S AU - Blair, Austin AU - Engel LS AU - Groth CP AU - Huynh TB AU - Kwok RK AU - Ramachandran G AU - Sandler DP AU - Stenzel MR AU - Stewart PA AB - In the GuLF Study, a study investigating possible adverse health effects associated with work on the oil spill response and clean-up (OSRC) following the Deepwater Horizon disaster in the Gulf of Mexico, we used a job-exposure matrix (JEM) approach to estimate exposures. The JEM linked interview responses of study participants to measurement data through exposure groups (EGs). Here we describe a systematic process used to develop transparent and precise EGs that allowed characterization of exposure levels among the large number of OSRC activities performed across the Gulf of Mexico over time and space. EGs were identified by exposure determinants available to us in our measurement database, from a substantial body of other spill-related information, and from responses provided by study participants in a detailed interview. These determinants included: job/activity/task, vessel and type of vessel, weathering of the released oil, area of the Gulf of Mexico, Gulf coast state, and time period. Over 3000 EGs were developed for inhalation exposure and applied to each of 6 JEMs of oil-related substances (total hydrocarbons, benzene, toluene, ethylbenzene, total xylene, and n-hexane). Subsets of those EGs were used for characterization of exposures to dispersants, particulate matter, and oil mist. The EGs allowed assignment to study participants of exposure estimates developed from measurement data or from estimation models through linkage in the JEM for the investigation of exposure-response relationships. [Description provided by NIOSH] AN - cdc:249287 KW - Benzene KW - Emergency Responders KW - Environmental Exposure KW - Epidemiology KW - Hazardous Substances KW - Hydrocarbons KW - Occupational Exposure KW - Occupational Health KW - Oil and Gas Industry KW - Respiratory System KW - Safety KW - Toluene KW - Xylenes KW - Deepwater Horizon; Oil industry; Oil spills; Spill cleanup; Disaster clean-up; Disaster recovery; Disaster sites; Occupational exposure; Exposure assessment; Exposure levels; Ethyl benzene; Xylene; Health effects; JEM; Job Exposure Matrix; Emergency responders; Humans; Inhalation; Inhalation studies; Chemicals; Chemical hazards; Hydrocarbons; Benzene; Toluene; n-Hexane; Job analysis; Task performance; Analytical models; Analytical processes; Epidemiology; Regression analysis; Statistical analysis; KW - Author Keywords: deepwater horizon; exposure assessment; exposure groups; oil weathering; Deepwater Horizon KW - Benzene KW - Emergency Responders KW - Environmental Exposure KW - Epidemiology KW - Hazardous Substances KW - Hydrocarbons KW - Occupational Exposure KW - Occupational Health KW - Oil and Gas Industry KW - Respiratory System KW - Safety KW - Toluene KW - Xylenes LA - eng PY - 2022/04/01 TI - Exposure group development in support of the NIEHS GuLF Study. VL - 66 UR - https://stacks.cdc.gov/view/cdc/249287 ER -
Trait rumination predicts elevated evening cortisol in sexual and gender minority young adults.

Figueroa WS ;

Hamilton K

2017/11/01 | National Institute for Occupational Safety and Health (NIOSH)

Stress may contribute to illness through the impaired recovery or sustained activity of stress-responsive biological systems. Rumination, or mental rehearsal of past stressors, may alter the body's stress-responsive systems by amplifying and prolonging exposure to physiological mediators, such as cortisol. The primary aim of the current investigati ...

12/01/2025

Title : Trait rumination predicts elevated evening cortisol in sexual and gender minority young adults. Personal Author(s) : Figueroa WS;Hamilton K;Hollenbeck C;Johnson RC;Manigault AW;Mendlein A;Scanlin M;Woody A;Zoccola PM; Published Date : 2017/11/01 URL : https://stacks.cdc.gov/view/cdc/249286 Figueroa WS et al. (2017). Trait rumination predicts elevated evening cortisol in sexual and gender minority young adults.. 14(11). Figueroa WS et al. "Trait rumination predicts elevated evening cortisol in sexual and gender minority young adults." 14, no. 11 (2017) Figueroa WS et al. "Trait rumination predicts elevated evening cortisol in sexual and gender minority young adults." vol. 14, no. 11, 2017 Export RIS Citation Information. TY - Journal Article AU - Figueroa WS AU - Hamilton K AU - Hollenbeck C AU - Johnson RC AU - Manigault AW AU - Mendlein A AU - Scanlin M AU - Woody A AU - Zoccola PM AB - Stress may contribute to illness through the impaired recovery or sustained activity of stress-responsive biological systems. Rumination, or mental rehearsal of past stressors, may alter the body's stress-responsive systems by amplifying and prolonging exposure to physiological mediators, such as cortisol. The primary aim of the current investigation was to test the extent to which the tendency to ruminate on stress predicts diminished diurnal cortisol recovery (i.e., elevated evening cortisol) in a sample of sexual and gender minority young adults. Participants included 58 lesbian, gay, bisexual, and transgender young adults (Mage = 25.0, SD = 4.1) who completed an initial online survey that assessed trait rumination and current depressed mood. Participants completed daily evening questionnaires and provided salivary cortisol samples at wake, 45 min post-wake, 12 h post-wake, and at bedtime over seven consecutive days. Trait rumination predicted significantly higher cortisol concentrations at bedtime, but was unrelated to other cortisol indices (e.g., morning cortisol, diurnal slope, total output). The association with trait rumination was not accounted for by daily negative affect, and was largely independent of depressed mood. These results have implications for identifying and treating those who may be at risk for impaired diurnal cortisol recovery and associated negative health outcomes. [Description provided by NIOSH] AN - cdc:249286 IS - 11 KW - Environmental Exposure KW - Mental Health KW - Occupational Health KW - Risk Assessment KW - Risk Factors KW - Safety KW - Surveys and Questionnaires KW - Humans; Stress; Biological factors; Physical stress; Physical reactions; Health effects; Exposure levels; Risk factors; Sampling; Psychological stress; Psychological effects; Questionnaires; KW - Author Keywords: rumination; cortisol; stress; recovery; sexual and gender minority; depressed mood KW - Environmental Exposure KW - Mental Health KW - Occupational Health KW - Risk Assessment KW - Risk Factors KW - Safety KW - Surveys and Questionnaires LA - eng PY - 2017/11/01 TI - Trait rumination predicts elevated evening cortisol in sexual and gender minority young adults. VL - 14 UR - https://stacks.cdc.gov/view/cdc/249286 ER -
The crossover of psychological distress from leaders to subordinates in teams: the role of abusive supervision, psychological capital, and team performance.

Li Y ;

Liu S

2016/04/01 | National Institute for Occupational Safety and Health (NIOSH)

This study examines the underlying mechanism of the crossover process in work teams. Drawing on Conservation of Resources theory, we hypothesize that a leader's psychological distress positively influences subordinates' psychological distress through abusive supervision. We further hypothesize that team performance attenuates the association betwee ...

12/01/2025

Title : The crossover of psychological distress from leaders to subordinates in teams: the role of abusive supervision, psychological capital, and team performance. Personal Author(s) : Li Y;Liu S;Wang Z;Yang L-Q; Published Date : 2016/04/01 Pages in Document : 142-153 URL : https://stacks.cdc.gov/view/cdc/249285 Li Y et al. (2016). The crossover of psychological distress from leaders to subordinates in teams: the role of abusive supervision, psychological capital, and team performance.. 21(2). Li Y et al. "The crossover of psychological distress from leaders to subordinates in teams: the role of abusive supervision, psychological capital, and team performance." 21, no. 2 (2016) Li Y et al. "The crossover of psychological distress from leaders to subordinates in teams: the role of abusive supervision, psychological capital, and team performance." vol. 21, no. 2, 2016 Export RIS Citation Information. TY - Journal Article AU - Li Y AU - Liu S AU - Wang Z AU - Yang L-Q AB - This study examines the underlying mechanism of the crossover process in work teams. Drawing on Conservation of Resources theory, we hypothesize that a leader's psychological distress positively influences subordinates' psychological distress through abusive supervision. We further hypothesize that team performance attenuates the association between a leader's psychological distress and abusive supervision. In addition, we expect that psychological capital attenuates the positive relationship between abusive supervision and subordinates' psychological distress. Participants were drawn from 86 business teams, and multisource data were collected. The hypotheses were tested with multilevel analysis. Results supported the crossover of psychological distress from leader to subordinates, and abusive supervision serves as a mediating mechanism. The positive relationship between a leader's distress and abusive supervision is stronger when team performance is lower. In addition, the positive relationship between abusive supervision and subordinates' psychological distress is stronger when subordinates' psychological capital is lower. [Description provided by NIOSH] AN - cdc:249285 IS - 2 KW - Occupational Health KW - Safety KW - Violence KW - Workload KW - Workplace KW - Work environment; Workers; Work capacity; Supervisory personnel; Psychological stress; Employees; Abuse; Stress; KW - Author Keywords: crossover; psychological distress; abusive supervision; team performance; psychological capital KW - Occupational Health KW - Safety KW - Violence KW - Workload KW - Workplace LA - eng PY - 2016/04/01 TI - The crossover of psychological distress from leaders to subordinates in teams: the role of abusive supervision, psychological capital, and team performance. VL - 21 UR - https://stacks.cdc.gov/view/cdc/249285 ER -
Perceived work exposures and expressed intervention needs among Michigan nail salon workers.

Dang JV ;

Le AB

2021/11/01 | National Institute for Occupational Safety and Health (NIOSH)

Background: Nail salon workers are an underserved population exposed to various occupational hazards. Comprised primarily of women and immigrants, these workers face challenges that further increase their workplace exposures and adverse health outcomes. Though previous studies have noted nail salon workers' exposures, these studies have yet to expl ...

12/01/2025

Title : Perceived work exposures and expressed intervention needs among Michigan nail salon workers. Personal Author(s) : Dang JV;Le AB;Rosemberg M-AS; Published Date : 2021/11/01 URL : https://stacks.cdc.gov/view/cdc/249284 Dang JV et al. (2021). Perceived work exposures and expressed intervention needs among Michigan nail salon workers.. 94(8). Dang JV and Le AB and Rosemberg M-AS "Perceived work exposures and expressed intervention needs among Michigan nail salon workers." 94, no. 8 (2021) Dang JV et al. "Perceived work exposures and expressed intervention needs among Michigan nail salon workers." vol. 94, no. 8, 2021 Export RIS Citation Information. TY - Journal Article AU - Dang JV AU - Le AB AU - Rosemberg M-AS AB - Background: Nail salon workers are an underserved population exposed to various occupational hazards. Comprised primarily of women and immigrants, these workers face challenges that further increase their workplace exposures and adverse health outcomes. Though previous studies have noted nail salon workers' exposures, these studies have yet to explore the workers' insights on intervention needs. This study among Michigan nail salon workers addresses this gap. Methods: This qualitative study was informed by the phenomenology methodological framework anchored within critical social theory. Participants were recruited from nail salons in Southeast Michigan to partake in focus groups. Interviews were recorded, transcribed, and analyzed using content analysis. Results: Three focus groups were conducted with 13 participants. Three major categories emerged. The first category, workers' perceived work-related stressors, included six themes: lack of standardized policies, regulations, education/training; disconnect between education/training and real-world practice; inadequate knowledge on exposures and safety protocols; unsafe nail products; customer pressure; and immigrant-related pressures. The second category, health issues perceived to be directly related to workplace exposures, included two themes: symptoms experienced due to contact with nail products and symptoms due to poor ergonomics. The third category, participants' perceived intervention needs, included four themes: continuing education; updates with new products; communication with key stakeholders; and partnership building and resource access. Conclusions: To our knowledge, this is the first qualitative study among U.S. nail salon workers focused in Midwest. In addition to the noted individual and organizational-level interventions, policy level implications are discussed given discrepancies in training and practices across states. [Description provided by NIOSH] AN - cdc:249284 IS - 8 KW - Emigration and Immigration KW - Ergonomics KW - Occupational Health KW - Safety KW - Staff Development KW - Stress, Psychological KW - Women KW - Nail technicians; Women; Immigrant workers; Worker health; Job stress; Training; Ergonomics; Work organization; Policy; KW - Author Keywords: Community-based research; Exposure; Focus groups; Occupational health; Nail salons KW - Emigration and Immigration KW - Ergonomics KW - Occupational Health KW - Safety KW - Staff Development KW - Stress, Psychological KW - Women LA - eng PY - 2021/11/01 TI - Perceived work exposures and expressed intervention needs among Michigan nail salon workers. VL - 94 UR - https://stacks.cdc.gov/view/cdc/249284 ER -
Short report: using targeted urine metabolomics to distinguish between manganese exposed and unexposed workers in a small occupational cohort.

Baker MG ;

Carter KA

2021/05/20 | National Institute for Occupational Safety and Health (NIOSH)

Objectives: Despite the widespread use of manganese (Mn) in industrial settings and its association with adverse neurological outcomes, a validated and reliable biomarker for Mn exposure is still elusive. Here, we utilize targeted metabolomics to investigate metabolic differences between Mn-exposed and -unexposed workers, which could inform a putat ...

12/01/2025

Title : Short report: using targeted urine metabolomics to distinguish between manganese exposed and unexposed workers in a small occupational cohort. Personal Author(s) : Baker MG;Carter KA;Raftery D;Simpson CD; Published Date : 2021/05/20 URL : https://stacks.cdc.gov/view/cdc/249283 Baker MG et al. (2021). Short report: using targeted urine metabolomics to distinguish between manganese exposed and unexposed workers in a small occupational cohort.. 9 Baker MG et al. "Short report: using targeted urine metabolomics to distinguish between manganese exposed and unexposed workers in a small occupational cohort." 9 (2021) Baker MG et al. "Short report: using targeted urine metabolomics to distinguish between manganese exposed and unexposed workers in a small occupational cohort." vol. 9, 2021 Export RIS Citation Information. TY - Journal Article AU - Baker MG AU - Carter KA AU - Raftery D AU - Simpson CD AB - Objectives: Despite the widespread use of manganese (Mn) in industrial settings and its association with adverse neurological outcomes, a validated and reliable biomarker for Mn exposure is still elusive. Here, we utilize targeted metabolomics to investigate metabolic differences between Mn-exposed and -unexposed workers, which could inform a putative biomarker for Mn and lead to increased understanding of Mn toxicity. Methods: End of shift spot urine samples collected from Mn exposed (n = 17) and unexposed (n = 15) workers underwent a targeted assay of 362 metabolites using LC-MS/MS; 224 were quantified and retained for analysis. Differences in metabolite abundances between exposed and unexposed workers were tested with a Benjamini-Hochberg adjusted Wilcoxon Rank-Sum test. We explored perturbed pathways related to exposure using a pathway analysis. Results: Seven metabolites were significantly differentially abundant between exposed and unexposed workers (FDR = 0.1), including n-isobutyrylglycine, cholic acid, anserine, beta-alanine, methionine, n-isovalerylglycine, and threonine. Three pathways were significantly perturbed in exposed workers and had an impact score >0.5: beta-alanine metabolism, histidine metabolism, and glycine, serine, and threonine metabolism. Conclusion: This is one of few studies utilizing targeted metabolomics to explore differences between Mn-exposed and -unexposed workers. Metabolite and pathway analysis showed amino acid metabolism was perturbed in these Mn-exposed workers. Amino acids have also been shown to be perturbed in other occupational cohorts exposed to Mn. Additional research is needed to characterize the biological importance of amino acids in the Mn exposure-disease continuum, and to determine how to appropriately utilize and interpret metabolomics data collected from occupational cohorts. [Description provided by NIOSH] AN - cdc:249283 KW - Biomarkers KW - Energy Metabolism KW - Manganese KW - Occupational Exposure KW - Occupational Health KW - Safety KW - Urine KW - Manganese; Biomarkers; Urine; Metabolites; Occupational exposure; Exposure assessment; Amino acids; Biological monitoring; KW - Author Keywords: occupational health; exposure assessment; targeted metabolomics; manganese exposure; biomonitoring KW - Biomarkers KW - Energy Metabolism KW - Manganese KW - Occupational Exposure KW - Occupational Health KW - Safety KW - Urine LA - eng PY - 2021/05/20 TI - Short report: using targeted urine metabolomics to distinguish between manganese exposed and unexposed workers in a small occupational cohort. VL - 9 UR - https://stacks.cdc.gov/view/cdc/249283 ER -
Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an air-liquid interface model of primary normal human-derived bronchial epithelial cells.

Battelli L ;

Bowers L

2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)

This study investigated the inhalation toxicity of the emissions from 3-D printing with acrylonitrile butadiene styrene (ABS) filament using an air-liquid interface (ALI) in vitro model. Primary normal human-derived bronchial epithelial cells (NHBEs) were exposed to ABS filament emission particles in an ALI for 4 h. The mean and mode diameters of A ...

12/01/2025

Title : Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an air-liquid interface model of primary normal human-derived bronchial epithelial cells. Personal Author(s) : Battelli L;Bowers L;Coyle J;Farcas MT;Friend SA;Hammer MA;Hammond, Duane R.;Kashon M;Mandler KW;Matheson JA;McKinney W;Orandle M;Qi C;Qian Y;Richardson D;Service S;Stefaniak, Aleksandr B.;Thomas TA; Published Date : 2022/03/23 URL : https://stacks.cdc.gov/view/cdc/249282 Battelli L et al. (2022). Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an air-liquid interface model of primary normal human-derived bronchial epithelial cells.. 186 Battelli L et al. "Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an air-liquid interface model of primary normal human-derived bronchial epithelial cells." 186 (2022) Battelli L et al. "Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an air-liquid interface model of primary normal human-derived bronchial epithelial cells." vol. 186, 2022 Export RIS Citation Information. TY - Abstract or Summary AU - Battelli L AU - Bowers L AU - Coyle J AU - Farcas MT AU - Friend SA AU - Hammer MA AU - Hammond, Duane R. AU - Kashon M AU - Mandler KW AU - Matheson JA AU - McKinney W AU - Orandle M AU - Qi C AU - Qian Y AU - Richardson D AU - Service S AU - Stefaniak, Aleksandr B. AU - Thomas TA AB - This study investigated the inhalation toxicity of the emissions from 3-D printing with acrylonitrile butadiene styrene (ABS) filament using an air-liquid interface (ALI) in vitro model. Primary normal human-derived bronchial epithelial cells (NHBEs) were exposed to ABS filament emission particles in an ALI for 4 h. The mean and mode diameters of ABS emitted particles in the medium were 175 +/- 24 nm and 153 +/- 15 nm, respectively. The average particle deposition per surface area of the epithelium was 2.29 × 107 +/- 1.47 × 107 particle/cm2, equivalent to an estimated average particle mass of 0.144 +/- 0.042 ug/cm2. Results showed exposure of NHBEs to ABS emissions did not significantly affect epithelium integrity, ciliation, mucus production, nor induce cytotoxicity. At 24 h after the exposure, significant increases in the pro-inflammatory markers IL-12p70, IFN-y, TNF-a, IL-17A, VEGF, and MIP-1a were noted in the basolateral cell culture medium of ABS-exposed cells compared to non-exposed chamber control cells. Results obtained from this study correspond with those from our previous in vivo studies, indicating that the increase in inflammatory mediators occur without associated membrane damage. Furthermore, the combination of the exposure chamber and the ALI-based model is promising for assessing 3-D printer emission-induced toxicity. to MWCNT. [Description provided by NIOSH] AN - cdc:249282 KW - Butadienes KW - Cells, Cultured KW - Cytotoxins KW - Environmental Exposure KW - Hazardous Substances KW - Occupational Health KW - Particulate Matter KW - Printing, Three-Dimensional KW - Respiratory System KW - Safety KW - Styrene KW - Acrylonitrile; Butadienes; Styrenes; Inhalation; Toxins; Emission sources; Three dimensional printing; 3D printing; In vitro study; Models; Particulates; Cytotoxicity; Exposure levels; Cell cultures KW - Butadienes KW - Cells, Cultured KW - Cytotoxins KW - Environmental Exposure KW - Hazardous Substances KW - Occupational Health KW - Particulate Matter KW - Printing, Three-Dimensional KW - Respiratory System KW - Safety KW - Styrene LA - eng PY - 2022/03/23 TI - Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an air-liquid interface model of primary normal human-derived bronchial epithelial cells. VL - 186 UR - https://stacks.cdc.gov/view/cdc/249282 ER -
Monitoring self-perceived occupational health inequities in Central America, 2011 and 2018.

Benavides FG ;

Delclos GL

2021/07/01 | National Institute for Occupational Safety and Health (NIOSH)

Objectives. To analyze changes in occupational health inequity between 2011 and 2018 among workers in Central America. Methods. Data were collected by face-to-face interviews at the workers' homes for the 2 Central America Working Conditions Surveys (n = 12 024 in 2011 and n = 9030 in 2018). We estimated health inequity gaps by means of absolute an ...

12/01/2025

Title : Monitoring self-perceived occupational health inequities in Central America, 2011 and 2018. Personal Author(s) : Benavides FG;Delclos GL;Gimeno Ruiz de Porras D;Lopez-Ruiz M;Merino-Salazar P;Rojas Garbanzo M;Silva-Peñaherrera M; Published Date : 2021/07/01 URL : https://stacks.cdc.gov/view/cdc/249281 Benavides FG et al. (2021). Monitoring self-perceived occupational health inequities in Central America, 2011 and 2018.. 111(7). Benavides FG et al. "Monitoring self-perceived occupational health inequities in Central America, 2011 and 2018." 111, no. 7 (2021) Benavides FG et al. "Monitoring self-perceived occupational health inequities in Central America, 2011 and 2018." vol. 111, no. 7, 2021 Export RIS Citation Information. TY - Journal Article AU - Benavides FG AU - Delclos GL AU - Gimeno Ruiz de Porras D AU - Lopez-Ruiz M AU - Merino-Salazar P AU - Rojas Garbanzo M AU - Silva-Peñaherrera M AB - Objectives. To analyze changes in occupational health inequity between 2011 and 2018 among workers in Central America. Methods. Data were collected by face-to-face interviews at the workers' homes for the 2 Central America Working Conditions Surveys (n = 12 024 in 2011 and n = 9030 in 2018). We estimated health inequity gaps by means of absolute and relative population attributable risks and the weighted Keppel index. We stratified all analyses by gender. Results. Between 2011 and 2018, the proportion of workers reporting poor self-perceived health decreased both in women (from 32% to 29%) and men (from 33% to 30%). However, the health inequity gaps remained wide in the 4 stratifiers. Measured by the Keppel index, health inequity gaps between countries increased from 22% to 39% in women and from 20% to 29% in men. Conclusions. While health improved between 2011 and 2018, health inequity gaps remained wide. Wider health inequity gaps were observed between countries than by gender, age, occupation, or education. Public Health Implications. This first benchmark of occupational health inequities in Central America could be useful when developing and evaluating the impact of public policies on work. [Description provided by NIOSH] AN - cdc:249281 IS - 7 KW - Mental Health KW - Nervous System KW - Occupational Health KW - Safety KW - Sex Characteristics KW - Occupational health disparities; Worker health; Gender factors; Mental health; Socioeconomics; Sociological factors; Surveillance; Policy KW - Mental Health KW - Nervous System KW - Occupational Health KW - Safety KW - Sex Characteristics LA - eng PY - 2021/07/01 TI - Monitoring self-perceived occupational health inequities in Central America, 2011 and 2018. VL - 111 UR - https://stacks.cdc.gov/view/cdc/249281 ER -
Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice.

Guppi S ;

Gutkin D

2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)

Crystalline nanocelluloses (CNC) have good electrical, optical, and mechanical properties which make them desirable for industrial applications. We investigated adverse reproductive outcomes due to inhalation exposure to CNC aerosol, generated from a bulk supply of wood pulp derived cellulose nanocrystals. C57BL6/J male mice were exposed to precise ...

12/01/2025

Title : Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice. Personal Author(s) : Guppi S;Gutkin D;Kisin ER;McKinney W;Shurin M;Shvedova AA; Published Date : 2022/03/23 URL : https://stacks.cdc.gov/view/cdc/249280 Guppi S et al. (2022). Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice.. 186 Guppi S et al. "Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice." 186 (2022) Guppi S et al. "Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice." vol. 186, 2022 Export RIS Citation Information. TY - Abstract or Summary AU - Guppi S AU - Gutkin D AU - Kisin ER AU - McKinney W AU - Shurin M AU - Shvedova AA AB - Crystalline nanocelluloses (CNC) have good electrical, optical, and mechanical properties which make them desirable for industrial applications. We investigated adverse reproductive outcomes due to inhalation exposure to CNC aerosol, generated from a bulk supply of wood pulp derived cellulose nanocrystals. C57BL6/J male mice were exposed to precise concentration of airborne CNC (5 mg/m3, 5 h/day, 5 days/week for 1st and 2nd week and 4 days/week for 3rd week). Cauda epididymal sperm samples, testes and serum were collected to evaluate sperm alterations, oxidative stress, changes in the hormonal levels and inflammatory cytokine responses and perform testes histopathology at 24 h, 2-, 6- and 12-months post exposure. CNC inhalation significantly elevated abnormality in sperm heads and tail/mid-piece as well as reduced the number of motile sperm at all time points of recovery. Sperm DNA integrity assessed as DNA fragmentation index was significantly elevated only 24h post CNC inhalation and then reduced to the air-control level. Interstitial edema and occasional dystrophic seminiferous tubules with arrested spermatogenesis and degenerating spermatocytes were found in testes 6- and 12-month post inhalation while no changes were seen at the early time points. CNC inhalation produced significant imbalance in the levels of testosterone (throughout the recovery time of 2-12 month) and luteinizing hormone (only at 12-month post exposure). Assessment of testicular oxidative damage showed significantly higher amounts of protein carbonyls at all time points of recovery. A hierarchical cluster analysis of 23 cytokines/chemokines/growth factors of the testes separated inflammatory cytokines (G-CSF, IL-6, IL-12p70 and MIP-1a) and revealed patterns that differentiate early responses from later time points. Serum cytokines at the later time points clustered together in the close proximity to the 24h acute response. Overall, these results demonstrate that CNC inhalation exposure induces sustained male reproductive toxicity observed up to 12 months of recovery. [Description provided by NIOSH] AN - cdc:249280 KW - Aerosols KW - Animals KW - Electricity KW - Endocrine System KW - Environmental Exposure KW - Laboratories KW - Occupational Health KW - Respiratory System KW - Risk Assessment KW - Risk Factors KW - Safety KW - Spermatogenesis KW - Urogenital Diseases KW - Urogenital System KW - Electrical properties; Mechanical properties; Reproductive effects; Reproductive system disorders; Inhalation; Exposure levels; Risk factors; Aerosols; Sampling; Oxidative stress; Hormones; Cytokines; Histopathology; DNA; Deoxyribonucleic acids; Spermatogenesis; Animals; Laboratory animals KW - Aerosols KW - Animals KW - Electricity KW - Endocrine System KW - Environmental Exposure KW - Laboratories KW - Occupational Health KW - Respiratory System KW - Risk Assessment KW - Risk Factors KW - Safety KW - Spermatogenesis KW - Urogenital Diseases KW - Urogenital System LA - eng PY - 2022/03/23 TI - Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice. VL - 186 UR - https://stacks.cdc.gov/view/cdc/249280 ER -
Macrophage-endothelial cell cross talk in ozone-oxidized carbon black nanoparticle exposure.

Bitounis D ;

Demokritous P

2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)

Apart from natural oxidation of particulate components of air pollution by the reactive gases like ozone (O3), oxidation of carbon black (CB) nanoparticle (NP) is also performed intentionally for industrial applications. Health impacts of these O3-oxidized CB (CBox) NPs are unknown. We hypothesized that macrophage uptake of CBox NPs and secretion o ...

12/01/2025

Title : Macrophage-endothelial cell cross talk in ozone-oxidized carbon black nanoparticle exposure. Personal Author(s) : Bitounis D;Demokritous P;Erdely A;Hussain S;Kodali V;Majumder N;Mazumder M;Nurkiewicz T;Velayutham M; Published Date : 2022/03/23 URL : https://stacks.cdc.gov/view/cdc/249279 Bitounis D et al. (2022). Macrophage-endothelial cell cross talk in ozone-oxidized carbon black nanoparticle exposure.. 186 Bitounis D et al. "Macrophage-endothelial cell cross talk in ozone-oxidized carbon black nanoparticle exposure." 186 (2022) Bitounis D et al. "Macrophage-endothelial cell cross talk in ozone-oxidized carbon black nanoparticle exposure." vol. 186, 2022 Export RIS Citation Information. TY - Abstract or Summary AU - Bitounis D AU - Demokritous P AU - Erdely A AU - Hussain S AU - Kodali V AU - Majumder N AU - Mazumder M AU - Nurkiewicz T AU - Velayutham M AB - Apart from natural oxidation of particulate components of air pollution by the reactive gases like ozone (O3), oxidation of carbon black (CB) nanoparticle (NP) is also performed intentionally for industrial applications. Health impacts of these O3-oxidized CB (CBox) NPs are unknown. We hypothesized that macrophage uptake of CBox NPs and secretion of soluble factors mediate enhanced endothelial cell damage abilities of CBox. CBox NPs were generated under controlled conditions (2 ppm O3 for 3 hours) in a custom developed inhalation exposure chamber. A detailed physicochemical characterization and dosimetry modelling of CB and CBox NPs was performed. Surface oxidation changes were confirmed using X-ray photo electron spectroscopy (XPS) and Fourier-transform infrared spectroscopy (FTIR). Acellular oxidant generation was confirmed using electron paramagnetic resonance (EPR) spectroscopy (free radical detection), and ferrous reducing ability of serum (FRAS) assay. In vivo and in vitro oxidant generation were confirmed using EPR, flow cytometry, immuno spin-trapping (IST) and FRAS assay. Mouse macrophages (RAW264.7), and C57BL/6 mice were exposed to CBox and CB NPS at human relevant exposure concentrations (0-50 µg/mL in vitro and 20 µg/mouse oropharyngeal aspiration in vivo). Conditioned media from the CBox exposed macrophage cultures was used to treat mouse endothelial cells (C166). Compared with pristine CB, CBox demonstrated 2-4-fold greater potential to generate free radicals under acellular, cellular and in vivo conditions. Pharmacological inhibitor studies confirmed an oxidant/MAPK/NFkb dependent pro-inflammatory response (gene and protein expression of CXCL9, 10, 11, TNF-a, IL-6) in mice and in in vitro exposed macrophages. Conditioned media from CBox treated macrophage induced greater endothelial dysfunction (monolayer permeability and inhibition of wound healing). Pharmacological inhibition confirmed a C-X-C chemokine receptor 3-mediated pathway involvement in the CBox toxicity. In summary, this work clearly demonstrates biological potency of CBox and warrant further mechanistic studies on oxidized nanomaterials safety assessment. [Description provided by NIOSH] AN - cdc:249279 KW - Air Pollution KW - Animals KW - Blood KW - Genetics KW - Laboratories KW - Macrophages KW - Occupational Health KW - Ozone KW - Particulate Matter KW - Safety KW - Oxidation; Particulates; Air pollution; Ozone; Nanoparticles; Macrophages; Endothelial cells; In vivo study; In vitro study; Animals; Laboratory animals; Proteins; Genes KW - Air Pollution KW - Animals KW - Blood KW - Genetics KW - Laboratories KW - Macrophages KW - Occupational Health KW - Ozone KW - Particulate Matter KW - Safety LA - eng PY - 2022/03/23 TI - Macrophage-endothelial cell cross talk in ozone-oxidized carbon black nanoparticle exposure. VL - 186 UR - https://stacks.cdc.gov/view/cdc/249279 ER -
Inhalation of 3-dimensional-(3D)-printing fumes affect the expression of markers associated with neural injury.

Farcas M ;

Jackson M

2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)

Inhalation of fumes and particulate generated by 3D-printing with plastics has been shown to induce mild systemic inflammation and oxidative stress. One plastic used for printing is polycarbonate (PC). PC contains organic solvents, bisphenols, and other chemicals that are known neurotoxicants. These neurotoxicants can be released as respirable fume ...

12/01/2025

Title : Inhalation of 3-dimensional-(3D)-printing fumes affect the expression of markers associated with neural injury. Personal Author(s) : Farcas M;Jackson M;Krajnak, Kristine M.;Matheson J;McKinney W;Qian Y;Thomas T;Waugh, Stacey; Published Date : 2022/03/23 URL : https://stacks.cdc.gov/view/cdc/249278 Farcas M et al. (2022). Inhalation of 3-dimensional-(3D)-printing fumes affect the expression of markers associated with neural injury.. 186 Farcas M et al. "Inhalation of 3-dimensional-(3D)-printing fumes affect the expression of markers associated with neural injury." 186 (2022) Farcas M et al. "Inhalation of 3-dimensional-(3D)-printing fumes affect the expression of markers associated with neural injury." vol. 186, 2022 Export RIS Citation Information. TY - Abstract or Summary AU - Farcas M AU - Jackson M AU - Krajnak, Kristine M. AU - Matheson J AU - McKinney W AU - Qian Y AU - Thomas T AU - Waugh, Stacey AB - Inhalation of fumes and particulate generated by 3D-printing with plastics has been shown to induce mild systemic inflammation and oxidative stress. One plastic used for printing is polycarbonate (PC). PC contains organic solvents, bisphenols, and other chemicals that are known neurotoxicants. These neurotoxicants can be released as respirable fumes when PC feed material is heated during printing. The goal of this study was to determine if inhaling fumes and particulate generated when printing with PC resulted in changes in inflammation, oxidative stress and transcripts and proteins involved in the formation of synapses in the central nervous system (CNS). Male Sprague Dawley rats (n = 60, 200-250 g at arrival) were exposed to filtered air or black PC particulate and fumes generated by 3 desktop-3D-printers (exposure 4 h/day (d)). The 4 h average particle concentration delivered to the animals breathing space was 500 µg/m3. Animals were exposed for 1d or 4 d/week until they had been exposed for 1, 4, 8, 15 or 30 d. The morning after the last exposure animals were euthanized and brain tissue was collected. Tissue from the left side was used for qRT-PCR and tissue from the right side was sectioned and used for immunohistochemistry. Cellular injury (fluorojade staining) was increased in the hippocampus and basal ganglia after 1 day of exposure to 3D fumes. However, staining returned to baseline levels in all groups after 4-30 d of exposure. Glial fibrillary acetic protein staining was also increased in these regions of the brain in 3D-exposed animals on all days of the experiment. In the basal ganglia, there was an increase in the transcription of inflammatory cytokines and anti-oxidant associated genes in 3D fume-exposed animals. Inhalation of 3D printing fumes resulted in an increase in the level of GFAP staining in both the hippocampus and the basal ganglia on all days of the experiment. There were also transient increases in markers of inflammation and oxidative stress. These finding are consistent with studies showing that bisphenol-A (a component of PC) induces oxidative stress and markers of oxidative damage and cellular injury. [Description provided by NIOSH] AN - cdc:249278 KW - Air Pollutants, Occupational KW - Animals KW - Immune System KW - Nervous System KW - Occupational Health KW - Plastics KW - Printing, Three-Dimensional KW - Safety KW - Toxicology KW - Toxicology; Animal studies; Three dimensional printing; 3D printing; Plastics; Neurotoxic effects; Fumes; Immune reaction; Oxidative stress; Cytokines KW - Air Pollutants, Occupational KW - Animals KW - Immune System KW - Nervous System KW - Occupational Health KW - Plastics KW - Printing, Three-Dimensional KW - Safety KW - Toxicology LA - eng PY - 2022/03/23 TI - Inhalation of 3-dimensional-(3D)-printing fumes affect the expression of markers associated with neural injury. VL - 186 UR - https://stacks.cdc.gov/view/cdc/249278 ER -
In search of balance: a conceptual and empirical integration of multiple meanings of work-family balance.

Allen TD ;

Butts MM

2017/02/01 | National Institute for Occupational Safety and Health (NIOSH)

This paper provides a framework that elaborates on four conceptualizations of work-family balance: additive spillover (unique effects of bi-directional conflict and enrichment), multiplicative spillover (interactive effects of lower conflict with higher enrichment), balance satisfaction (one's attitude toward resource allocation across work and fam ...

12/01/2025

Title : In search of balance: a conceptual and empirical integration of multiple meanings of work-family balance. Personal Author(s) : Allen TD;Butts MM;Casper WJ;Wayne JH; Published Date : 2017/02/01 Pages in Document : 176-210 URL : https://stacks.cdc.gov/view/cdc/249277 Allen TD et al. (2017). In search of balance: a conceptual and empirical integration of multiple meanings of work-family balance.. 70(1). Allen TD et al. "In search of balance: a conceptual and empirical integration of multiple meanings of work-family balance." 70, no. 1 (2017) Allen TD et al. "In search of balance: a conceptual and empirical integration of multiple meanings of work-family balance." vol. 70, no. 1, 2017 Export RIS Citation Information. TY - Journal Article AU - Allen TD AU - Butts MM AU - Casper WJ AU - Wayne JH AB - This paper provides a framework that elaborates on four conceptualizations of work-family balance: additive spillover (unique effects of bi-directional conflict and enrichment), multiplicative spillover (interactive effects of lower conflict with higher enrichment), balance satisfaction (one's attitude toward resource allocation across work and family roles) and balance effectiveness (one's interdependent self-evaluation of meeting shared expectations across work and family roles). We describe the conceptual differences among these approaches and hypothesize how they operate differently in predicting work and family attitudes and performance. Relative weights analyses showed that additive spillover was the most important predictor of work attitudes (organizational commitment, job satisfaction, and turnover intent), followed by balance satisfaction and effectiveness. However, balance satisfaction and effectiveness together were the most important predictors of family satisfaction and job and family performance. Mediation tests revealed that unique and interactive effects of bidirectional conflict and enrichment related to work and family attitudes and performance indirectly through balance satisfaction and effectiveness. We discuss implications of these findings and offer suggestions to guide future research and theory on work-family balance. [Description provided by NIOSH] AN - cdc:249277 IS - 1 KW - Occupational Health KW - Safety KW - Work-family balance; Attitude; Performance capability; Occupational psychology; Employee satisfaction KW - Occupational Health KW - Safety LA - eng PY - 2017/02/01 TI - In search of balance: a conceptual and empirical integration of multiple meanings of work-family balance. VL - 70 UR - https://stacks.cdc.gov/view/cdc/249277 ER -
Socioeconomic status and psychological stress: examining intersection with race, sex and US geographic region in the REasons for Geographic and Racial Differences in Stroke study.

Bennett A ;

Carson AP

2022/04/01 | National Institute for Occupational Safety and Health (NIOSH)

Socioeconomic status (SES) is a well-established determinant of health. Disparities in stress are thought to partially account for SES-health disparities. We tested whether multiple indicators of SES show similar associations with psychological stress and whether race, sex, and geographic region moderate associations. Participants (n = 26,451) are ...

12/01/2025

Title : Socioeconomic status and psychological stress: examining intersection with race, sex and US geographic region in the REasons for Geographic and Racial Differences in Stroke study. Personal Author(s) : Bennett A;Carson AP;Cundiff JM;Howard VJ;Judd SE; Published Date : 2022/04/01 Pages in Document : 340-349 URL : https://stacks.cdc.gov/view/cdc/249276 Bennett A et al. (2022). Socioeconomic status and psychological stress: examining intersection with race, sex and US geographic region in the REasons for Geographic and Racial Differences in Stroke study.. 38(2). Bennett A et al. "Socioeconomic status and psychological stress: examining intersection with race, sex and US geographic region in the REasons for Geographic and Racial Differences in Stroke study." 38, no. 2 (2022) Bennett A et al. "Socioeconomic status and psychological stress: examining intersection with race, sex and US geographic region in the REasons for Geographic and Racial Differences in Stroke study." vol. 38, no. 2, 2022 Export RIS Citation Information. TY - Journal Article AU - Bennett A AU - Carson AP AU - Cundiff JM AU - Howard VJ AU - Judd SE AB - Socioeconomic status (SES) is a well-established determinant of health. Disparities in stress are thought to partially account for SES-health disparities. We tested whether multiple indicators of SES show similar associations with psychological stress and whether race, sex, and geographic region moderate associations. Participants (n = 26,451) are from a well-characterized national cohort of Black and White US adults aged 45 years or older. Psychological stress was measured using the 4-item perceived stress scale. Income was assessed as annual household income and education as highest level of education completed. Occupation was assessed during a structured interview and subsequently coded hierarchically. For all sex-race-region groups, the largest SES-stress associations were for income and the smallest were for occupation. Race moderated SES-stress associations, such that income and education were more closely associated with stress in Black adults than White adults. Additionally, education was more strongly associated with stress in individuals living in the stroke belt region. Black Americans with lower income and education reported greater psychological stress and may be at higher risk for disease through stress-related pathways. Thus, which SES indicator is examined and for whom may alter the magnitude of the association between SES and psychological stress. [Description provided by NIOSH] AN - cdc:249276 IS - 2 KW - Aging KW - Epidemiology KW - Healthcare Disparities KW - Occupational Health KW - Race Factors KW - Safety KW - Sex Characteristics KW - Epidemiology; Psychological stress; Health disparities; Racial factors; Socioeconomics; Sex factors; Age groups; Stress-related illnesses; KW - Author Keywords: national cohort; race; sex; socioeconomic status; stress KW - Aging KW - Epidemiology KW - Healthcare Disparities KW - Occupational Health KW - Race Factors KW - Safety KW - Sex Characteristics LA - eng PY - 2022/04/01 TI - Socioeconomic status and psychological stress: examining intersection with race, sex and US geographic region in the REasons for Geographic and Racial Differences in Stroke study. VL - 38 UR - https://stacks.cdc.gov/view/cdc/249276 ER -
Effect of welding fume exposure on silica-induced pulmonary toxicity in rats.

Joseph P ;

McKinney W

2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)

Mixed exposures to silica and welding fume are common in certain occupations. It is currently undetermined what health burden workers exposed to both silica and welding fume experience. The objective of this study was to determine the effect of welding fume on the lung response to silica exposure. Male Fischer 344 rats were exposed to air or silica ...

12/01/2025

Title : Effect of welding fume exposure on silica-induced pulmonary toxicity in rats. Personal Author(s) : Joseph P;McKinney W;Mustafa M;Sager TM;Umbright CM; Published Date : 2022/03/23 Pages in Document : 83-84 URL : https://stacks.cdc.gov/view/cdc/249275 Joseph P et al. (2022). Effect of welding fume exposure on silica-induced pulmonary toxicity in rats.. 186 Joseph P et al. "Effect of welding fume exposure on silica-induced pulmonary toxicity in rats." 186 (2022) Joseph P et al. "Effect of welding fume exposure on silica-induced pulmonary toxicity in rats." vol. 186, 2022 Export RIS Citation Information. TY - Abstract or Summary AU - Joseph P AU - McKinney W AU - Mustafa M AU - Sager TM AU - Umbright CM AB - Mixed exposures to silica and welding fume are common in certain occupations. It is currently undetermined what health burden workers exposed to both silica and welding fume experience. The objective of this study was to determine the effect of welding fume on the lung response to silica exposure. Male Fischer 344 rats were exposed to air or silica (15 mg/m3, 6 hrs/day, 5 days). At 5- and 11-months post-silica exposure, rats received welding fume (20 mg/m3, 4 hrs/day, 4 days/week for 4 weeks) by inhalation. At 1 day post welding fume exposure bronchoalveolar lavage was conducted to assess pulmonary toxicity based on lactate dehydrogenase activity, oxidant production, cell counts, and cytokines. Lung gene expression changes were also assessed. The results showed that both silica and welding fume exposures resulted in lung toxicity, at both post-exposure time points. Both additive and synergistic lung responses were detected, based on the parameters analyzed. For example, silica or welding fume exposure, alone, resulted in neutrophil infiltration of 250 and 625 times, respectively, compared to the air-exposed controls at 12 months post-exposure. The combined exposure to silica and welding fume, however, caused neutrophil infiltration that was 1392 times higher compared to air controls. Silica or welding fume exposure alone resulted in significant increases in measured cytokine levels, compared to controls. However, the combined exposure of silica and welding fume caused a greater elevation of measured cytokine levels, at both post-exposure timepoints. For example, measured levels of MIP-2 were 37-fold and 35-fold higher in the silica alone and welding fume alone animals, respectively. However, the silica and welding fume combined exposure facilitated an additive effect, where the measured MIP-2 level was 45-fold higher. Furthermore, global gene expression changes in the lungs were detected in all exposure groups, at both 6- and 12-months post-exposure. For example, silica exposure alone resulted in 125 and 750 significantly differentially expressed genes (SDEGs), while the welding fume alone group had 1068 and 2255 SDEGs, and the silica-welding fume combined exposure had 1808 and 1910 SDEGs, at the 6- and 12-month time intervals, respectively. Together, these results suggest an additive/synergistic effect of the combined silica and welding fume exposure on the assessed lung toxicity parameters. [Description provided by NIOSH] AN - cdc:249275 KW - Animals KW - Lung KW - Occupational Health KW - Respiratory System KW - Safety KW - Silicon Dioxide KW - Toxicology KW - Welding KW - Toxicology; Welding fumes; Welders; Silica; Animal studies; Lung tissue; Cytokines; Pulmonary effects; Mixed exposures KW - Animals KW - Lung KW - Occupational Health KW - Respiratory System KW - Safety KW - Silicon Dioxide KW - Toxicology KW - Welding LA - eng PY - 2022/03/23 TI - Effect of welding fume exposure on silica-induced pulmonary toxicity in rats. VL - 186 UR - https://stacks.cdc.gov/view/cdc/249275 ER -
Toxicity of fluorinated and fluorine-free foams: potential implications on firefighter renal health.

Beitel S ;

Burgess J

2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)

Military Specification aqueous film forming foams (AFFF)-typically comprised of complex mixtures of per- and polyfluorinated alkyl substances (PFAS), solvents, stabilizers, and wetting agents-are used to extinguish liquid fuel fires. Health concerns from use of AFFF have emerged because of studies documenting elevated PFAS serum levels in some fire ...

12/01/2025

Title : Toxicity of fluorinated and fluorine-free foams: potential implications on firefighter renal health. Personal Author(s) : Beitel S;Burgess J;Calkins M;Coyle J;Rojanasakul L;Ruyle B;Slitt A;Stueckle, Todd A.;Sunderland E; Published Date : 2022/03/23 Pages in Document : 66 URL : https://stacks.cdc.gov/view/cdc/249274 Beitel S et al. (2022). Toxicity of fluorinated and fluorine-free foams: potential implications on firefighter renal health.. 186 Beitel S et al. "Toxicity of fluorinated and fluorine-free foams: potential implications on firefighter renal health." 186 (2022) Beitel S et al. "Toxicity of fluorinated and fluorine-free foams: potential implications on firefighter renal health." vol. 186, 2022 Export RIS Citation Information. TY - Abstract or Summary AU - Beitel S AU - Burgess J AU - Calkins M AU - Coyle J AU - Rojanasakul L AU - Ruyle B AU - Slitt A AU - Stueckle, Todd A. AU - Sunderland E AB - Military Specification aqueous film forming foams (AFFF)-typically comprised of complex mixtures of per- and polyfluorinated alkyl substances (PFAS), solvents, stabilizers, and wetting agents-are used to extinguish liquid fuel fires. Health concerns from use of AFFF have emerged because of studies documenting elevated PFAS serum levels in some firefighter populations, including firefighters with known exposure to AFFF, compared to the public. PFAS exposure is associated with increased risk for chronic conditions, including decreased kidney function and cancer. With a scheduled phase out of AFFF containing PFAS in the US by 2024, synthetic fluorine-free foams (SFFF) are an attractive replacement; however, little is known about their potential occupational health risks. This project's objective was to conduct rapid high-throughput screening of cultured human kidney cells to identify potential adverse outcome pathways associated with renal injury. Commercial AFFF and SFFF were analyzed for total fluorine using combustion ion chromatography. Human renal proximal tubule epithelial cells with over-expressed organic anion transporter 1 (RPTEC-OAT1) were exposed to serial dilutions of 5 AFFF (A-E), 5 SFFF (F-J), and 7 frequently detected PFAS in cell culture media for 6 - 24 hours. High-throughput screening for cytotoxicity, mitochondrial polarization, and intracellular reactive oxygen species (ROS) levels of exposed cells was performed by multiplex fluorescence and image analysis using a high content imaging platform. All tested AFFF resulted in acute cytotoxicity (IC50) at concentrations ranging from 109-262 ppm (v:v) while SFFF F exhibited the greatest toxicity at IC50 = 3.3 ppm (v:v). Toxicity in SFFF G - J ranged from 33 to 278 ppm. Perfluorooctane sulfonate (PFOS) and perfluorooctanoate acid displayed IC50 at 74 and 200 ppm (m:v), respectively, while all C4 to C6 PFAS were not acutely cytotoxic. A majority of AFFF, perfluorohexanesulfonic acid (PHFxS), and PFOS caused decreases in mitochondrial depolarization at sub-toxic doses. SFFF F enhanced intracellular ROS dose-dependently 6 and 24 hours post-exposure while the other treatments did not differ from unexposed controls. In summary, AFFF showed similar kidney cell cytotoxicity to C8 PFAS-exposed cells suggesting PFAS within AFFF contributes to kidney cell cytotoxicity. Effects of SFFF varied substantially, signifying additional need for future hazard characterization. [Description provided by NIOSH] AN - cdc:249274 KW - Cytotoxins KW - Firefighters KW - Fuel Oils KW - Occupational Health KW - Safety KW - Toxicology KW - Toxicology; Fuels; Fire extinguishing agents; Fire suppression; Fire fighters; Health effects; Renal toxicity; Kidney toxins; Cellular effects; Cytotoxicity; Per- and polyfluoroalkyl substances; PFAS KW - Cytotoxins KW - Firefighters KW - Fuel Oils KW - Occupational Health KW - Safety KW - Toxicology LA - eng PY - 2022/03/23 TI - Toxicity of fluorinated and fluorine-free foams: potential implications on firefighter renal health. VL - 186 UR - https://stacks.cdc.gov/view/cdc/249274 ER -
Mindfulness, emotion regulation, and social threat.

Creswell JD ;

Lindsay EK

2017/05/10 | National Institute for Occupational Safety and Health (NIOSH)

This chapter considers the mindfulness and emotion regulation, a comprehensive contemporary model of emotion regulation processes and discusses how mindfulness may impact these emotion regulation processes. Additional downstream emotion regulation processes that may be impacted by the effects of mindfulness on attentional deployment include the fee ...

12/01/2025

Title : Mindfulness, emotion regulation, and social threat. Personal Author(s) : Creswell JD;Lindsay EK;Rahl H;Slutsky J; Published Date : 2017/05/10 Pages in Document : 79-93 URL : https://stacks.cdc.gov/view/cdc/249273 Creswell JD et al. (2017). Mindfulness, emotion regulation, and social threat.. Creswell JD et al. "Mindfulness, emotion regulation, and social threat." (2017) Creswell JD et al. "Mindfulness, emotion regulation, and social threat." , 2017 Export RIS Citation Information. TY - Book AU - Creswell JD AU - Lindsay EK AU - Rahl H AU - Slutsky J AB - This chapter considers the mindfulness and emotion regulation, a comprehensive contemporary model of emotion regulation processes and discusses how mindfulness may impact these emotion regulation processes. Additional downstream emotion regulation processes that may be impacted by the effects of mindfulness on attentional deployment include the feedback and repertoire components of emotion regulation flexibility. There are several initial studies suggesting that mindfulness can foster more effective use of emotion regulation strategies and buffer social threat responses. J. J. Gross delineates the processes that must occur to successfully regulate one's emotions over time, moving from situation selection to situation modification, attentional deployment, cognitive change, and response modulation. Attentional deployment is the emotion regulation process of directing attention toward or away from specific stimuli in order to influence emotional responding. When confronted with a threatening situation, such as giving a presentation or being interviewed for a job, one may either deploy attention towards feelings of stress and anxiety or away from them. [Description provided by NIOSH] AN - cdc:249273 KW - Mental Health KW - Nervous System KW - Occupational Health KW - Safety KW - Mental health; Psychology; Psychological factors; Models KW - Mental Health KW - Nervous System KW - Occupational Health KW - Safety LA - eng PB - Routledge PY - 2017/05/10 TI - Mindfulness, emotion regulation, and social threat. UR - https://stacks.cdc.gov/view/cdc/249273 ER -
The Joint Commission's new and revised workplace violence prevention standards for hospitals: a major step forward toward improved quality and safety.

Arnetz JE

2022/04/01 | National Institute for Occupational Safety and Health (NIOSH)

Workplace violence poses a significant threat to the health, safety, and well-being of health care workers and has negative implications for their productivity, retention, and the quality of care they provide to patients. The problem is not new. Violence from patients toward health care workers has been recognized as an occupational hazard for deca ...

12/01/2025

Title : The Joint Commission's new and revised workplace violence prevention standards for hospitals: a major step forward toward improved quality and safety. Personal Author(s) : Arnetz JE Published Date : 2022/04/01 Pages in Document : 241-245 URL : https://stacks.cdc.gov/view/cdc/249272 Arnetz JE (2022). The Joint Commission's new and revised workplace violence prevention standards for hospitals: a major step forward toward improved quality and safety.. 48(4). Arnetz JE "The Joint Commission's new and revised workplace violence prevention standards for hospitals: a major step forward toward improved quality and safety." 48, no. 4 (2022) Arnetz JE "The Joint Commission's new and revised workplace violence prevention standards for hospitals: a major step forward toward improved quality and safety." vol. 48, no. 4, 2022 Export RIS Citation Information. TY - Journal Article AU - Arnetz JE AB - Workplace violence poses a significant threat to the health, safety, and well-being of health care workers and has negative implications for their productivity, retention, and the quality of care they provide to patients. The problem is not new. Violence from patients toward health care workers has been recognized as an occupational hazard for decades, with the earliest studies coming from psychiatric/mental health settings. By the early 1990s, violence was becoming a recognized occupational risk in general health care settings as well. Since then, research on violence in health care has increased exponentially, helping to raise awareness of the problem. Despite this, the incidence of violence has increased, including during the ongoing COVID-19 pandemic. Estimates of costs associated with non-fatal workplace violence in health care settings range from $109,000 per year for treatment and indemnity among injured nurses to over $330,000 per year in a single hospital system. These estimates do not include the costs of the psychological trauma, fear, and work dissatisfaction that may develop in employees' response to workplace violence or patient-related costs. Patient-related costs may be due to direct injury caused by a violent act, but they can be indirect as well, resulting from gaps in care due to staff absences caused by violence-related injury. ... The key elements just outlined are included in the new Joint Commission standards, which also provide links to resources that can guide hospitals in efforts to fulfill the standard requirements. Workplace violence has been recognized as a serious issue by The Joint Commission for well-over a decade. Since 2008, the Joint Commission has issued Sentinel Event Alerts and Quick Safety newsletters that have highlighted violence and the need for preventive measures. Topics have ranged from "behaviors that undermine a culture of safety" to "physical and verbal violence against health care workers to "de-escalation in health care." In addition, The Joint Commission has published multiple blog posts presentations, and a podcast on workplace violence and its prevention in hospitals. [Description provided by NIOSH] AN - cdc:249272 IS - 4 KW - Behavior KW - Health Personnel KW - Mental Disorders KW - Mental Health KW - Occupational Health KW - Safety KW - Violence KW - Workplace KW - Workplace violence; Assaults; Health care workers; Costs; Legislation; Regulations; Safety culture; Behavioral disorders; Health standards; Psychological effects KW - Behavior KW - Health Personnel KW - Mental Disorders KW - Mental Health KW - Occupational Health KW - Safety KW - Violence KW - Workplace LA - eng PY - 2022/04/01 TI - The Joint Commission's new and revised workplace violence prevention standards for hospitals: a major step forward toward improved quality and safety. VL - 48 UR - https://stacks.cdc.gov/view/cdc/249272 ER -

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