Exposure group development in support of the NIEHS GuLF Study.

Details

• Personal Author:
  Banerjee S ; Blair, Austin ; Engel LS ; Groth CP ; Huynh TB ; Kwok RK ; Ramachandran G ; Sandler DP ; Stenzel MR ; Stewart PA
• Description:
  In the GuLF Study, a study investigating possible adverse health effects associated with work on the oil spill response and clean-up (OSRC) following the Deepwater Horizon disaster in the Gulf of Mexico, we used a job-exposure matrix (JEM) approach to estimate exposures. The JEM linked interview responses of study participants to measurement data through exposure groups (EGs). Here we describe a systematic process used to develop transparent and precise EGs that allowed characterization of exposure levels among the large number of OSRC activities performed across the Gulf of Mexico over time and space. EGs were identified by exposure determinants available to us in our measurement database, from a substantial body of other spill-related information, and from responses provided by study participants in a detailed interview. These determinants included: job/activity/task, vessel and type of vessel, weathering of the released oil, area of the Gulf of Mexico, Gulf coast state, and time period. Over 3000 EGs were developed for inhalation exposure and applied to each of 6 JEMs of oil-related substances (total hydrocarbons, benzene, toluene, ethylbenzene, total xylene, and n-hexane). Subsets of those EGs were used for characterization of exposures to dispersants, particulate matter, and oil mist. The EGs allowed assignment to study participants of exposure estimates developed from measurement data or from estimation models through linkage in the JEM for the investigation of exposure-response relationships. [Description provided by NIOSH]
• Subjects:
  Benzene Emergency Responders Environmental Exposure Epidemiology Hazardous Substances Hydrocarbons Occupational Exposure Occupational Health Oil And Gas Industry Respiratory System Safety Toluene Xylenes

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• Keywords:
  Author Keywords: Deepwater Horizon; Exposure Assessment; Exposure Groups; Oil Weathering; Deepwater Horizon Deepwater Horizon; Oil Industry; Oil Spills; Spill Cleanup; Disaster Clean-up; Disaster Recovery; Disaster Sites; Occupational Exposure; Exposure Assessment; Exposure Levels; Ethyl Benzene; Xylene; Health Effects; JEM; Job Exposure Matrix; Emergency Responders; Humans; Inhalation; Inhalation Studies; Chemicals; Chemical Hazards; Hydrocarbons; Benzene; Toluene; N-Hexane; Job Analysis; Task Performance; Analytical Models; Analytical Processes; Epidemiology; Regression Analysis; Statistical Analysis;
• ISSN:
  2398-7308
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Maryland ; North Carolina ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 9 ; Pennsylvania ; Virginia ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  66
• NIOSHTIC Number:
  nn:20064959
• Citation:
  Ann Work Expo Health 2022 Apr; 66(Suppl 1):i23-i55
• Contact Point Address:
  Mark R. Stenzel, Exposure Assessment Applications, LLC, 6045 N. 27th. St., Arlington, VA 22207
• Email:
  Mark_StenzelEAApps@hotmail.com
• CAS Registry Number:
  Benzene (CAS RN 71-43-2) ; Ethylbenzene (CAS RN 100-41-4) ; Toluene (CAS RN 108-88-3) ; Xylene (CAS RN 1330-20-7)
• Federal Fiscal Year:
  2022
• Performing Organization:
  Drexel University, Philadelphia, Pennsylvania
• Peer Reviewed:
  True
• Start Date:
  20160901
• Source Full Name:
  Annals of Work Exposures and Health
• Supplement:
  1
• End Date:
  20190831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:38d0f728d0a8eddc23fb1444b7fefdaf4aa683a49863dac400e7ca468df27958aec5bbb239a3fe5b804adb4ba1059d5c9727900743c133aabfe1e7a2d86a438e
• Download URL:
  https://stacks.cdc.gov/view/cdc/249287/cdc_249287_DS1.pdf
• File Type:
  [PDF - 331.54 KB ]