Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Durukan, Duygu ; Doyle, Michelle ; Murray, Gerald ; Bodiyabadu, Kaveesha ; Vodstrcil, Lenka ; Chow, Eric P.F. ; Jensen, Jorgen S. ; Fairley, Christopher K. ; Aguirre, Ivette ; Bradshaw, Catriona S.
• Description:
  Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin.
• Subjects:
  AMR Antimicrobial Resistance Dispatch Doxycycline Doxycycline And Sitafloxacin Combination Therapy For Treating Highly Resistant Mycoplasma Genitalium Dual-class Resistance Macrolide Resistance Multidrug Resistance Mycoplasma Genitalium Quinolone Resistance Sexually Transmitted Infections Sitafloxacin

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• Source:
  Emerg Infect Dis. 26(8):1870-1874
• Pubmed ID:
  32687029
• Pubmed Central ID:
  PMC7392426
• Document Type:
  Journal Article
• Volume:
  26
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:639fd2230bef78bc5a64391e294b26114cda9f8e37b84ab6d4984d44c561bf05
• Download URL:
  https://stacks.cdc.gov/view/cdc/91541/cdc_91541_DS1.pdf
• File Type:
  [PDF - 1.94 MB ]