i
The role of epidemiology in the regulation of oral contraceptives.
-
Published Date:
1984 Jul-Aug
Source:Public Health Rep. 99(4):350-354Language:English
- File Format:
- RIS
Details:
-
Alternative Title:Public Health Rep
-
Personal Author:
-
Description:The U.S. Food and Drug Administration (FDA) has relied to a great degree on epidemiologic studies in the regulation of oral contraceptives (OC). These epidemiologic studies range from individual case reports of adverse reactions to case-control studies and cohort studies. Important findings about adverse reactions to OCs have been communicated through "labeling," which includes information leaflets provided as package inserts for physicians and patients. Also, the FDA communicates its position through publications in medical journals, the FDA Drug Bulletin, public advisory committee meetings, workshops, and symposia. The agency responds to new epidemiologic information; labeling guidelines are under continuing review and revision. Patterns of oral contraceptive use have been affected by the dissemination of this information. There has been a decline in the use of OCs, a shift to formulations with lesser steroidal content, and a greater emphasis on OC use in optimal groups, such as young, nonsmoking women. Considered for future epidemiologic studies that may have an impact on regulatory action are a clarification of the role of various progestins in regard to blood lipid alteration and atherogenesis, a delineation of the possible persistence of cardiovascular risk after termination of OC use, and further clarification in regard to neoplasia, particularly breast and cervical carcinoma.
-
Subject:
-
Pubmed ID:6431481
-
Pubmed Central ID:PMCnull
-
Document Type:
-
Collection(s):
-
Main Document Checksum:urn:sha256:34b1ab1b7a39ced1076eb9c40d7ba5ddf5577d14d5ce39abe93b400c906e344f
- File Type:
-
Supporting Files:No Additional Files
Related Documents:
-
-
Personal Author:McCutcheon, J WPublished Date:1984 Jul-AugSource:Public Health Rep. 99(4):360-364Description:Nitrite has been used for centuries to preserve, color, and flavor meat. Today, about 10 billion pounds of cured meat products are produced annually, ...
Personal Author:Eckhardt, K W ; Hendershot, Gerry E. ;Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):410-415Description:The long downward trend in the practice of breast feeding was reversed during the 1972-73 period. Data from the National Survey of Family Growth condu...
Personal Author:Silverman, CPublished Date:1984 Jul-AugSource:Public Health Rep. 99(4):369-373Description:Epidemiologic studies of medically and environmentally exposed populations have been central to establishing ionizing radiation as a cause of malignan...
Personal Author:West, M DPublished Date:1984 Jul-AugSource:Public Health Rep. 99(4):391-400Description:The number of employed registered nurses (RNs) in the United States stood at an all-time high of 1.3 million in 1980. This paper, using life table tec...
Personal Author:Kristiansen, C M ; Harding, C M ;Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):384-388Description:The relationship between measures of social desirability and various preventive health behaviors was examined directly for 235 females and 171 males f...
Personal Author:Nighswander, T SPublished Date:1984 Jul-AugSource:Public Health Rep. 99(4):400-404Description:In a retrospective study, 100 randomly selected, high utilizers of ambulatory care services in 1972 were followed for a 6-year period, 1973-78. The 22...
Personal Author:Nightingale, S LPublished Date:1984 Jul-AugSource:Public Health Rep. 99(4):333-338Description:The controversy over Laetrile is nearly at an end, the worthlessness of the drug having been demonstrated beyond reasonable doubt. But the Laetrile ex...
Personal Author:Lewis, W FPublished Date:1984 Jul-AugSource:Public Health Rep. 99(4):415-424Description:Marital status has been associated with a wide variety of health indices and health practices. To better understand the relation of marital status to ...
Personal Author:Silver, B J ; Goldston, S E ; ...Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):374-384Description:The control of stress and violent behavior is 1 of the 15 priority areas addressed in the Public Health Service's Objectives for the Nation. The Natio...
Personal Author:Cordle, F ; Miller, S A ;Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):365-369Description:The increasing use of nonnutritive sweeteners and the widely publicized 1969 ban on cyclamate led to additional investigations in rodents of the carci...
Personal Author:Chabner, B A ; Wittes, R ; ...Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):355-360Description:The National Cancer Institute since 1955 has been charged with responsibility for discovering new anti-cancer agents and bringing them to clinical tri...
Personal Author:Pasley, B H ; Standfast, S J ; ...Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):424-429Description:A physician survey was conducted in 13 counties surrounding Albany and Syracuse, N.Y., to determine estrogen prescribing patterns for treatment of pro...
Personal Author:Coulehan, J L ; Michaels, R H ; ...Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):404-409Description:During a 7-year period ending June 30, 1980, the annual incidence of all Haemophilus influenzae type b disease among Navajo children less than 5 years...
-
You May Also Like:
-
Personal Author:Cordle, F ; Miller, S A ;Published Date:1984 Jul-AugSource:Public Health Rep. 99(4):365-369Description:The increasing use of nonnutritive sweeteners and the widely publicized 1969 ban on cyclamate led to additional investigations in rodents of the carci...
Personal Author:Finkel, M JPublished Date:1984 May-JunSource:Public Health Rep. 99(3):313-316Description:Through the combined efforts of agencies and organizations in the public and private sector, drugs have been made available that would not have been a...
Personal Author:Nightingale, S LPublished Date:1984 Jul-AugSource:Public Health Rep. 99(4):333-338Description:The controversy over Laetrile is nearly at an end, the worthlessness of the drug having been demonstrated beyond reasonable doubt. But the Laetrile ex...
Personal Author:Hayes, A HPublished Date:1983 May-JunSource:Public Health Rep. 98(3):207-210Description:The Food and Drug Administration is engaged in a broad-based program to make consumers more aware of the potential impact on health of sodium consumpt...
Exit Notification/Disclaimer Policy
Links with this icon indicate that you are leaving the CDC website.- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.
- Linking to a non-federal Website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
- You will be subject to the destination website's privacy policy when you follow the link.
- CDC is not responsible for Section 508 compliance (accessibility) on other federal or private websites.
Have Questions?
Visit CDC InfoCall 800-232-4636
