Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Maryandyshev, Andrey ; Pontali, Emanuele ; Tiberi, Simon ; Akkerman, Onno ; Ganatra, Shashank ; ... More +
Maryandyshev, Andrey ; Pontali, Emanuele ; Tiberi, Simon ; Akkerman, Onno ; Ganatra, Shashank ; Sadutshang, Tsetan Dorji ; Alffenaar, Jan-Willem ; Amale, Rohit ; Mullerpattan, Jai ; Topgyal, Sonam ; Udwadia, Zarir Farokh ; Centis, Rosella ; D’Ambrosio, Lia ; Sotgiu, Giovanni ; Migliori, Giovanni Battista Less -
Description:
We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolongation but no arrhythmias occurred. Use of this therapy is justified for patients with limited options.
Subjects:
[+]
Adolescent Adult Antitubercular Agents Diarylquinolines Dispatch Drug Therapy, Combination Extensively Drug-Resistant Tuberculosis/drug Therapy Female Humans Male Nitroimidazoles Oxazoles Tuberculosis, Pulmonary Young Adult
Source:
Emerg Infect Dis. 23(10):1718-1721.
Pubmed ID:
28758888
Pubmed Central ID:
PMC5621558
Document Type:
Journal Article
Place as Subject:
Europe ; Netherlands ; India ; Russia ; Italy ; ... More +
Europe ; Netherlands ; India ; Russia ; Italy ; United Kingdom ; Switzerland Less -
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:0cbaa4068cb2ec61d1337b9cccbd985214cd04284291b9795ebef8396dc73071
Download URL:
https://stacks.cdc.gov/view/cdc/48994/cdc_48994_DS1.pdf
File Type:

Supporting Files

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