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Multidrug-Resistant Tuberculosis
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  1. Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection
    Personal Author:
    Hingley-Wilson, Suzanne M.; Casey, Rosalyn; Connell, David; Bremang, Samuel; Evans, Jason T.; Hawkey, Peter M.; Smith, Grace E.; Jepson, Annette; Philip, Stuart; Kon, Onn Min; Lalvani, Ajit;
    Published Date:
    Jul 2013
    Source:
    Emerg Infect Dis. 19(7):1138-1141.
    Description:
    Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mi...
    File Type:
    Filetype[PDF - 410.62 KB]
  2. Double infection with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis.
    Personal Author:
    Niemann, S.; Richter, E.; Rüsch-Gerdes, S.; Schlaak, M.; Greinert, U.;
    Published Date:
    2000 Sep-Oct
    Source:
    Emerg Infect Dis. 6(5):548-551.
    Description:
    An immunocompetent patient was dually infected with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis (TB). The multidrug-resistant strain, which belongs to the W- strain/Beijing family, was first isolated after 3 months of t...
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  3. Does Alcohol Consumption during Multidrug-resistant Tuberculosis Treatment Affect Outcome?
    Personal Author:
    Duraisamy, Karthickeyan; Mrithyunjayan, Sunilkumar; Ghosh, Smita; Nair, Sreenivas Achuthan; Balakrishnan, Shibu; Subramoniapillai, Jayasankar; Oeltmann, John E.; Moonan, Patrick K.; Kumar, Ajay M. V.;
    Published Date:
    Jun 2014
    Source:
    Ann Am Thorac Soc. 11(5):712-718
    Description:
    RationaleIndia reports the largest number of multidrug-resistant tuberculosis cases in the world; yet, no longitudinal study has assessed factors related to treatment outcomes under programmatic conditions in the public sector.ObjectivesTo describe d...
    File Type:
    Filetype[PDF - 282.96 KB]
  4. Epidemiology of Primary Multidrug-Resistant Tuberculosis, Vladimir Region, Russia
    Personal Author:
    Ershova, Julia V.; Volchenkov, Grigory V.; Kaminski, Dorothy A.; Somova, Tatiana R.; Kuznetsova, Tatiana A.; Kaunetis, Natalia V.; Cegielski, J. Peter; Kurbatova, Ekaterina V.;
    Published Date:
    Nov 2015
    Source:
    Emerg Infect Dis. 21(11):2048-2051
    Description:
    We studied the epidemiology of drug-resistant tuberculosis (TB) in Vladimir Region, Russia, in 2012. Most cases of multidrug-resistant TB (MDR TB) were caused by transmission of drug-resistant strains, and >33% were in patients referred for testing a...
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  5. Tuberculosis Drug Resistance and HIV Infection, the Netherlands
    Personal Author:
    Haar, Catharina Hendrika; Cobelens, Frank G.J.; Kalisvaart, Nico A.; van der Have, Jan J.; van Gerven, Paul J.H.J.; van Soolingen, Dick;
    Published Date:
    May 2007
    Source:
    Emerg Infect Dis. 13(5):776-778.
    Description:
    In the Netherlands during 1993-2001, multidrug-resistant tuberculosis among newly diagnosed patients was more frequent in those with HIV coinfection (5/308, 1.6%) than in those with no HIV infection (39/646, 0.6%; adjusted odds ratio 3.43, p=0.015). ...
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    Filetype[PDF - 1.43 MB]