Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle

Okada, Hiroyuki; Iwamaru, Yoshifumi; Imamura, Morikazu; Miyazawa, Kohtaro; Matsuura, Yuichi; Masujin, Kentaro; Murayama, Yuichi; Yokoyama, Takashi

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Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle

Supporting Files Public Domain

Feb 2017
By Okada, Hiroyuki ; Iwamaru, Yoshifumi ; Imamura, Morikazu ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Okada, Hiroyuki ; Iwamaru, Yoshifumi ; Imamura, Morikazu ; Miyazawa, Kohtaro ; Matsuura, Yuichi ; Masujin, Kentaro ; Murayama, Yuichi ; Yokoyama, Takashi
Description:

To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle.
Subjects:

Atypical Bovine Spongiform Encephalopathy Cattle Dispatch L-BSE L-type Oral Transmission Oral Transmission Of L-Type Bovine Spongiform Encephalopathy Agent Among Cattle Prion Prions And Related Diseases Zoonoses
Source:

Emerg Infect Dis. 23(2):284-287.
Pubmed ID:

28098532
Pubmed Central ID:

PMC5324790
Document Type:

Journal Article
Volume:

23
Issue:

2
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:eb8a44df8977061e26448e1d2b6abcade0e92538754a0b8f1dede8899d63e835
Download URL:

https://stacks.cdc.gov/view/cdc/44388/cdc_44388_DS1.pdf
File Type:

[PDF - 1.96 MB ]

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