Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Mestre-Francés, Nadine; Nicot, Simon; Rouland, Sylvie; Biacabe, Anne-Gaëlle; Quadrio, Isabelle; Perret-Liaudet, Armand; Baron, Thierry; Verdier, Jean-Michel

doi:10.3201/eid1801.111092

i

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Supporting Files Public Domain

Jan 2012
By Mestre-Francés, Nadine ; Nicot, Simon ; Rouland, Sylvie
http://dx.doi.org/10.3201/eid1801.111092

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Alternative Title:

Emerg Infect Dis
Personal Author:

Mestre-Francés, Nadine ; Nicot, Simon ; Rouland, Sylvie ; Biacabe, Anne-Gaëlle ; Quadrio, Isabelle ; Perret-Liaudet, Armand ; Baron, Thierry ; Verdier, Jean-Michel
Description:

We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.
Subjects:
Source:

Emerg Infect Dis. 18(1):142-145.
Document Type:

Journal Article
Volume:

18
Issue:

1
Download URL:

https://stacks.cdc.gov/view/cdc/23645/cdc_23645_DS1.pdf
File Type:

[PDF - 360.64 KB]
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:166f79cb0ecefbf65f79f7c90c9bdbcd5064609dd9b0f076c6fbcb9bf6258b17

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