Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Mestre-Francés, Nadine; Nicot, Simon; Rouland, Sylvie; Biacabe, Anne-Gaëlle; Quadrio, Isabelle; Perret-Liaudet, Armand; Baron, Thierry; Verdier, Jean-Michel

doi:10.3201/eid1801.111092

i

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Supporting Files Public Domain

Jan 2012
By Mestre-Francés, Nadine ; Nicot, Simon ; Rouland, Sylvie ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Mestre-Francés, Nadine ; Nicot, Simon ; Rouland, Sylvie ; Biacabe, Anne-Gaëlle ; Quadrio, Isabelle ; Perret-Liaudet, Armand ; Baron, Thierry ; Verdier, Jean-Michel
Description:

We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.
Subjects:

Animal Feed Animals Bovine Spongiform Encephalopathy Brain BSE Cattle Cheirogaleidae Dispatch Encephalopathy, Bovine Spongiform Female L-type BSE Male Mouse Lemur Non-human Primate Model Oral Transmission Primate Prion Prions Prions And Related Diseases
Source:

Emerg Infect Dis. 18(1):142-145.
Document Type:

Journal Article
Volume:

18
Issue:

1
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:166f79cb0ecefbf65f79f7c90c9bdbcd5064609dd9b0f076c6fbcb9bf6258b17
Download URL:

https://stacks.cdc.gov/view/cdc/23645/cdc_23645_DS1.pdf
File Type:

[PDF - 360.64 KB ]

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