Accumulation of L-type Bovine Prions in Peripheral Nerve Tissues

Iwamaru, Yoshifumi; Imamura, Morikazu; Matsuura, Yuichi; Masujin, Kentaro; Shimizu, Yoshihisa; Shu, Yujing; Kurachi, Megumi; Kasai, Kazuo; Murayama, Yuichi; Fukuda, Shigeo; Onoe, Sadao; Hagiwara, Ken’ichi; Yamakawa, Yoshio; Sata, Tetsutaro; Mohri, Shirou; Okada, Hiroyuki; Yokoyama, Takashi

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Accumulation of L-type Bovine Prions in Peripheral Nerve Tissues

Jul 2010
By Iwamaru, Yoshifumi ; Imamura, Morikazu ; Matsuura, Yuichi ; ...
Source: Emerg Infect Dis. 16(7):1151-1154.

[PDF-559.97 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Iwamaru, Yoshifumi ; Imamura, Morikazu ; Matsuura, Yuichi ; Masujin, Kentaro ; Shimizu, Yoshihisa ; ... More +

Iwamaru, Yoshifumi ; Imamura, Morikazu ; Matsuura, Yuichi ; Masujin, Kentaro ; Shimizu, Yoshihisa ; Shu, Yujing ; Kurachi, Megumi ; Kasai, Kazuo ; Murayama, Yuichi ; Fukuda, Shigeo ; Onoe, Sadao ; Hagiwara, Ken’ichi ; Yamakawa, Yoshio ; Sata, Tetsutaro ; Mohri, Shirou ; Okada, Hiroyuki ; Yokoyama, Takashi Less -
Description:

We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally challenged cattle. As with classical BSE prions, L-type BSE prions accumulated in central and peripheral nerve tissues.
Subjects:

[+]

Animals Atypical Bovine Spongiform Encephalopathy Cattle Creutzfeldt-Jacob Disease Dispatch Distribution Encephalopathy, Bovine Spongiform L-type Nerve Tissues Neurodegenerative Disorder Peripheral Nerves Prion Prions Transmissibility Zoonoses
Source:

Emerg Infect Dis. 16(7):1151-1154.
Document Type:

Journal Article
Volume:

16
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:43723e48b919ce3cfe52597503e9db73b8fe6897ed7f5d26e3d7da16c64da246
Download URL:

https://stacks.cdc.gov/view/cdc/18192/cdc_18192_DS1.pdf
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