Molecular Epidemiology of Rift Valley Fever Virus

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Grobbelaar, Antoinette A. ; Weyer, Jacqueline ; Leman, Patricia A. ; Kemp, Alan ; Paweska, Janusz T. ; Swanepoel, Robert
• Description:
  Phylogenetic relationships were examined for 198 Rift Valley fever virus isolates and 5 derived strains obtained from various sources in Saudi Arabia and 16 countries in Africa during a 67-year period (1944-2010). A maximum-likelihood tree prepared with sequence data for a 490-nt section of the Gn glycoprotein gene showed that 95 unique sequences sorted into 15 lineages. A 2010 isolate from a patient in South Africa potentially exposed to co-infection with live animal vaccine and wild virus was a reassortant. The potential influence of large-scale use of live animal vaccine on evolution of Rift Valley fever virus is discussed.
• Subjects:
  Animals Base Sequence Communicable Diseases, Emerging Disease Outbreaks DNA, Viral Genes, Viral Humans Molecular Epidemiology Phylogeny Recombination, Genetic Research Rift Valley Fever Ruminants Viral Proteins Viral Vaccines

  More +
• Source:
  Emerg Infect Dis. 17(12):2270-2276.
• Document Type:
  Journal Article
• Place as Subject:
  Africa ; Saudi Arabia ; South Africa
• Location:
  Africa ; Middle East
• Volume:
  17
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:e8dbf06f6e0511b67b3a3555a2022eb03a59342be8d14cfe1ac3c887efd8a7dd
• Download URL:
  https://stacks.cdc.gov/view/cdc/23799/cdc_23799_DS1.pdf
• File Type:
  [PDF - 338.04 KB ]