Molecular Epidemiology of Rabies in Southern People’s Republic of China

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Tao, Xiao-Yan ; Tang, Qing ; Li, Hao ; Mo, Zhao-Jun ; Zhang, Hong ; Wang, Ding-Ming ; Zhang, Qiang ; Song, Miao ; Velasco-Villa, Andres ; Wu, Xianfu ; Rupprecht, Charles E. ; Liang, Guo-Dong
• Description:
  In recent years, the number of human rabies cases in the People's Republic of China has increased during severe epidemics in 3 southern provinces (Guizhou, Guangxi, and Hunan). To analyze the causes of the high incidence of human rabies in this region, during 2005-2007, we collected 2,887 brain specimens from apparently healthy domestic dogs used for meat consumption in restaurants, 4 specimens from suspected rabid dogs, and 3 from humans with rabies in the 3 provinces. Partial nucleoprotein gene sequences were obtained from rabies-positive specimens. Phylogenetic relationships and distribution of viruses were determined. We infer that the spread of rabies viruses from high-incidence regions, particularly by long-distance movement or transprovincial translocation of dogs caused by human-related activities, may be 1 cause of the recent massive human rabies epidemics in southern China.
• Subjects:
  Animals Base Sequence Communicable Diseases, Emerging Disease Outbreaks Disease Reservoirs DNA, Viral DNA Primers Dog Diseases Dogs Genes, Viral Humans Meat Molecular Epidemiology Nucleocapsid Proteins Phylogeny Rabies Rabies Virus Research

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• Source:
  Emerg Infect Dis. 15(8):1192-1198.
• Document Type:
  Journal Article
• Place as Subject:
  China
• Location:
  Asia
• Volume:
  15
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:815d92e0c9d788e5ede1fbd046eef9f9d299c9872fe9de639bd4f840c3508485
• Download URL:
  https://stacks.cdc.gov/view/cdc/17483/cdc_17483_DS1.pdf
• File Type:
  [PDF - 511.01 KB ]