Intergenogroup Recombination in Sapoviruses

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hansman, Grant S. ; Takeda, Naokazu ; Oka, Tomoichiro ; Oseto, Mitsukai ; Hedlund, Kjell-Olof ; Katayama, Kazuhiko
• Description:
  Sapovirus, a member of the family Caliciviridae, is an etiologic agent of gastroenteritis in humans and pigs. Analyses of the complete genome sequences led us to identify the first sapovirus intergenogroup recombinant strain. Phylogenetic analysis of the nonstructural region (i.e., genome start to capsid start) grouped this strain into genogroup II, whereas the structural region (i.e., capsid start to genome end) grouped this strain into genogroup IV. We found that a recombination event occurred at the polymerase and capsid junction. This is the first report of intergenogroup recombination for any calicivirus and highlights a possible route of zoonoses because sapovirus strains that infect pig species belong to genogroup III.
• Subjects:
  Base Sequence Genes, Viral Genome, Viral Genotype Molecular Sequence Data Phylogeny Recombination, Genetic
• Source:
  Emerg Infect Dis. 11(12):1914-1920.
• Document Type:
  Journal Article
• Volume:
  11
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b773c8e4604e82171da1931db228494cb419b723a89845f4892480982f122a59
• Download URL:
  https://stacks.cdc.gov/view/cdc/15964/cdc_15964_DS1.pdf
• File Type:
  [PDF - 386.48 KB ]