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Asynchronous Onset of Clinical Disease in BSE-Infected Macaques
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Jul 2013
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Source: Emerg Infect Dis. 19(7):1125-1127.
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Alternative Title:Emerg Infect Dis
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Description:To estimate the effect of the variability of prion disease onset on primary bovine spongiform encephalopathy transmission to humans, we studied 6 cynomolgus macaques. The preclinical incubation period was significantly prolonged in 2 animals, implying that onset of variant Creutzfeldt-Jacob disease in humans could be more diverse than previously expected.
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