BSE-associated Prion-Amyloid Cardiomyopathy in Primates

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Krasemann, Susanne ; Mearini, Giulia ; Krämer, Elisabeth ; Wagenführ, Katja ; Schulz-Schaeffer, Walter ; Neumann, Melanie ; Bodemer, Walter ; Kaup, Franz-Josef ; Beekes, Michael ; Carrier, Lucie ; Aguzzi, Adriano ; Glatzel, Markus
• Description:
  Prion amyloidosis occurred in the heart of 1 of 3 macaques intraperitoneally inoculated with bovine spongiform encephalopathy prions. This macaque had a remarkably long duration of disease and signs of cardiac distress. Variant Creutzfeldt-Jakob disease, caused by transmission of bovine spongiform encephalopathy to humans, may manifest with cardiac symptoms from prion-amyloid cardiomyopathy.
• Subjects:
  Amyloidosis Animals Bovine Spongiform Encephalopathy Brain BSE Cardiomyopathies Cardiomyopathy Cattle Creutzfeldt-Jakob Syndrome Dispatch Encephalopathy, Bovine Spongiform Macaca Mulatta Muscle, Skeletal Myocardium Primates Prions PrPSc Variant Creutzfeldt-Jakob Disease VCJD

  More +
• Source:
  Emerg Infect Dis. 19(6):985-988.
• Document Type:
  Journal Article
• Volume:
  19
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:314eed7f63818472cc380f4e8380480b7d06a507c2420b7b36938c1bd6ad8b6c
• Download URL:
  https://stacks.cdc.gov/view/cdc/18920/cdc_18920_DS1.pdf
• File Type:
  [PDF - 348.13 KB ]