Differentiation of Prions from L-type BSE versus Sporadic Creutzfeldt-Jakob Disease

Nicot, Simon; Bencsik, Anna; Morignat, Eric; Mestre-Francés, Nadine; Perret-Liaudet, Armand; Baron, Thierry

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Differentiation of Prions from L-type BSE versus Sporadic Creutzfeldt-Jakob Disease

Supporting Files Public Domain

Dec 2012
By Nicot, Simon ; Bencsik, Anna ; Morignat, Eric ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Nicot, Simon ; Bencsik, Anna ; Morignat, Eric ; Mestre-Francés, Nadine ; Perret-Liaudet, Armand ; Baron, Thierry
Description:

We compared transmission characteristics for prions from L-type bovine spongiform encephalopathy and MM2-cortical sporadic Creutzfeldt-Jakob disease in the Syrian golden hamster and an ovine prion protein-transgenic mouse line and isolated distinct prion strains. Our findings suggest the absence of a causal relationship between these diseases, but further investigation is warranted.
Subjects:

Animals Bioassay Bovine Spongiform Encephalopathy Brain BSE Cattle Creutzfeldt-Jakob Disease Creutzfeldt-Jakob Syndrome Cricetinae Dispatch Encephalopathy, Bovine Spongiform Hamster Human Humans L-type Lemur Mice Mice, Transgenic Prions Prions And Related Diseases SCJD Sporadic Strain
Source:

Emerg Infect Dis. 18(12):2028-2031.
Document Type:

Journal Article
Volume:

18
Issue:

12
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:fc4c6b8d30c8ceb56a85ec4e46ed97f937474d92b52473faa01c1f11039a9297
Download URL:

https://stacks.cdc.gov/view/cdc/18793/cdc_18793_DS1.pdf
File Type:

[PDF - 1.07 MB ]

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