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Eliminating Spiked Bovine Spongiform Encephalopathy Agent Activity from Heparin
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July 29 2020
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Source: Emerg Infect Dis. 26(10):2478-2480
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Alternative Title:Emerg Infect Dis
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Personal Author:
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Description:US manufacturers, concerned about bovine spongiform encephalopathy (BSE), ceased marketing bovine heparin in the 1990s. Recent short supplies of safe porcine heparin suggest that reintroducing bovine heparin might benefit public health. We purified heparin from crude bovine extract spiked with BSE agent, removing substantial infectivity and abnormal prion proteins (PrP|).
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Pubmed ID:32723431
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Pubmed Central ID:PMC7510749
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Volume:26
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Issue:10
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