Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Peiris, J.S. Malik ; Tang, Wing-Hong ; Chan, Kwok-Hung ; Khong, Pek-Lan ; Guan, Yi ; ... More +
Peiris, J.S. Malik ; Tang, Wing-Hong ; Chan, Kwok-Hung ; Khong, Pek-Lan ; Guan, Yi ; Lau, Yu-Lung ; Chiu, Susan S. Less -
Description:
Human metapneumovirus (HMPV) is a newly discovered pathogen thought to be associated with respiratory disease. We report the results of a study of 587 children hospitalized with respiratory infection over a 13-month period. HMPV was detected in the nasopharyngeal aspirates from 32 (5.5%) children by reverse transcription-polymerase chain reaction. HMPV infection was associated with clinical diagnoses of pneumonia (36%), asthma exacerbation (23%), or acute bronchiolitis (10%). When compared to those with respiratory syncytial virus infection, children with HMPV infection were older, and wheezing was more likely to represent asthma exacerbation rather than acute bronchiolitis. HMPV viral activity peaked during the spring-summer period in Hong Kong. Phylogenetically, all HMPV virus strains from Hong Kong belonged to one of the two genetic lineages previously described. HMPV contributed to 441.6 hospital admissions per 100,000 population <6 years of age.
Subjects:
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Child Children Female Fever Hong Kong Hospitalization Human Metapneumovirus Humans Infant Influenza, Human Influenza A Virus Male Metapneumovirus Paramyxoviridae Infections Phylogeny Research Respiratory Infections Respiratory Syncytial Viruses Respiratory Syncytial Virus Infections Respiratory Tract Infections Wheezing
Source:
Emerg Infect Dis. 9(6):628-633.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:2abfc9f3ee35930f3e4600827dafa4fbf2557e449043854d0ba14fff967083ab
Download URL:
https://stacks.cdc.gov/view/cdc/14219/cdc_14219_DS1.pdf
File Type:

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