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CDC Public Access

CDC Stacks Public Health Publications

Items in this collection are manuscripts and articles written by CDC or CDC-funded authors, and published in scholarly journals outside CDC. These items are available in compliance with the 2024 update of CDC-GA-2013-01 CDC Public Access to CDC-Funded Publications, available at: https://stacks.cdc.gov/view/cdc/159734.

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Showing 25141 - 25160 of 27881 results
  • Age Affects Quantity but Not Quality of Antibody Responses after Vaccination with an Inactivated Flavivirus Vaccine against TickBorne Encephalitis
    Age Affects Quantity but Not Quality of Antibody Responses after Vaccination with an Inactivated Flavivirus Vaccine against Tick-Borne Encephalitis
    Stiasny, Karin ;
    Aberle, Judith H.
    Mar 26 2012 | PLoS One. 2012; 7(3).
    The impairment of immune functions in the elderly (immunosenescence) results in post-vaccination antibody titers that are significantly lower than in young individuals. It is, however, a controversial question whether also the quality of antibodies declines with age. In this study, we have therefore investigated the age-dependence of functional cha ...
    Supporting Files Public Domain
  • Spatial cluster detection using dynamic programming
    Spatial cluster detection using dynamic programming
    Sverchkov, Yuriy ;
    Jiang, Xia
    Mar 25 2012 | BMC Med Inform Decis Mak. 2012; 12:22.
    BackgroundThe task of spatial cluster detection involves finding spatial regions where some property deviates from the norm or the expected value. In a probabilistic setting this task can be expressed as finding a region where some event is significantly more likely than usual. Spatial cluster detection is of interest in fields such as biosurveilla ...
    Supporting Files
  • Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin
    Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin
    Samhan-Arias, Alejandro K. ;
    Ji, Jing
    Mar 23 2012 | Biochim Biophys Acta. 2012; 1818(10):2413-2423.
    Oxidized phospholipid species are important, biologically relevant, lipid signaling molecules that usually exist in low abundance in biological tissues. Along with their inherent stability issues, these oxidized lipids present themselves as a challenge in their detection and identification. Often times, oxidized lipid species can co-chromatograph w ...
    Supporting Files
  • Rapid Simultaneous Detection of Clostridium sordellii and Clostridium perfringens in Archived Tissues by a Novel PCRBased Microsphere Assay Diagnostic Implications for PregnancyAssociated Toxic Shock Syndrome Cases
    Rapid, Simultaneous Detection of Clostridium sordellii and Clostridium perfringens in Archived Tissues by a Novel PCR-Based Microsphere Assay: Diagnostic Implications for Pregnancy-Associated Toxic Shock Syndrome Cases
    Bhatnagar, Julu ;
    DeLeon-Carnes, Marlene
    Mar 22 2012 | Infect Dis Obstet Gynecol. 2012; 2012.
    Clostridium sordellii and Clostridium perfringens are infrequent human pathogens; however, the case-fatality rates for the infections are very high, particularly in obstetric C. sordellii infections (>90%). Deaths from Clostridium sordellii and Clostridium perfringens toxic shock (CTS) are sudden, and diagnosis is often challenging. Formalin-fixed, ...
    Supporting Files Public Domain
  • Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya
    Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya
    McCollum, Andrea M ;
    Schneider, Kristan A
    Mar 22 2012 | Malar J. 2012; 11:77.
    BackgroundUnderstanding the origin and spread of mutations associated with drug resistance, especially in the context of combination therapy, will help guide strategies to halt and prevent the emergence of resistance. Unfortunately, studies have assessed these complex processes when resistance is already highly prevalent. Even further, information ...
    Supporting Files Public Domain
  • The effects of a psychosocial dimension of socioeconomic position on survival occupational prestige and mortality among US working adults
    The effects of a psychosocial dimension of socioeconomic position on survival: occupational prestige and mortality among US working adults
    Christ, Sharon L. ;
    Fleming, Lora E.
    Mar 22 2012 | Sociol Health Illn. 34(7):1103-1117.
    The association between education or income and mortality has been explored in great detail. These measures capture both the effects of material disadvantage on health and the psychosocial impacts of a low socioeconomic position on health. When explored independently of educational attainment and income, occupational prestige - a purely perceptual ...
    Supporting Files
  • Awareness of and behaviors related to childtomother transmission of cytomegalovirus
    Awareness of and behaviors related to child-to-mother transmission of cytomegalovirus☆
    Cannon, Michael J. ;
    Westbrook, Kyresa
    Mar 21 2012 | Prev Med. 54(5):351-357.
    ObjectiveCongenital cytomegalovirus (CMV) infection is a common cause of hearing loss and intellectual disability. We assessed CMV knowledge and the frequency of women's behaviors that may enable CMV transmission to inform strategies for communicating prevention messages to women.MethodsWe analyzed survey responses from 4184 participants (2181 wome ...
    Supporting Files
  • Implementing Preventive Chemotherapy through an Integrated National Neglected Tropical Disease Control Program in Mali
    Implementing Preventive Chemotherapy through an Integrated National Neglected Tropical Disease Control Program in Mali
    Dembélé, Massitan ;
    Bamani, Sanoussi
    Mar 20 2012 | PLoS Negl Trop Dis. 2012; 6(3).
    BackgroundMali is endemic for all five targeted major neglected tropical diseases (NTDs). As one of the five ‘fast-track’ countries supported with the United States Agency for International Development (USAID) funds, Mali started to integrate the activities of existing disease-specific national control programs on these diseases in 2007. The ultima ...
    Supporting Files Public Domain
  • A Common HLADPA1 Variant Is Associated with Hepatitis B Virus Infection but Fails to Distinguish Active from Inactive Caucasian Carriers
    A Common HLA-DPA1 Variant Is Associated with Hepatitis B Virus Infection but Fails to Distinguish Active from Inactive Caucasian Carriers
    Vermehren, Johannes ;
    Lötsch, Jörn
    Mar 20 2012 | PLoS One. 2012; 7(3).
    Background and AimsChronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV infection in Asian populations. Most significant associations were observed for the A alleles of HLA-DPA ...
    Supporting Files Public Domain
  • Dual Protection Use to Prevent STIs and Unintended Pregnancy
    Dual Protection Use to Prevent STIs and Unintended Pregnancy
    Sales, Jessica M. ;
    Whiteman, Maura K.
    Mar 20 2012 | Infect Dis Obstet Gynecol. 2012; 2012.
    No Description
    Supporting Files Public Domain
  • Associations of Prenatal Exposure to Organophosphate Pesticide Metabolites with Gestational Age and Birth Weight
    Associations of Prenatal Exposure to Organophosphate Pesticide Metabolites with Gestational Age and Birth Weight
    Rauch, Stephen A. ;
    Braun, Joe M.
    Mar 20 2012 | Environ Health Perspect. 2012; 120(7):1055-1060.
    Prenatal exposure to organophosphate (OP) insecticides, a widely used class of pesticides, may be associated with decreased gestational age and lower birth weight. Single nucleotide polymorphisms in paroxanase (PON1) enzyme genotypes may modify the relationships between OP exposure and perinatal outcomes.|We examined the relationship of prenatal OP ...
    Supporting Files Public Domain
  • Standing orders for influenza and pneumococcal polysaccharide vaccination Correlates identified in a national survey of US Primary care physicians
    Standing orders for influenza and pneumococcal polysaccharide vaccination: Correlates identified in a national survey of U.S. Primary care physicians
    Albert, Steven M ;
    Nowalk, Mary Patricia
    Mar 20 2012 | BMC Fam Pract. 2012; 13:22.
    BackgroundStanding orders programs (SOPs) allow non-physician medical staff to assess eligibility and administer vaccines without a specific physician's order. SOPs increase vaccination rates but are underutilized.MethodIn 2009, correlates of SOPs use for influenza vaccine and pneumococcal polysaccharide vaccination (PPV) were assessed in a nationa ...
    Supporting Files
  • Occupation and ThreeYear Incidence of Respiratory Symptoms and Lung Function Decline The ARIC Study
    Occupation and Three-Year Incidence of Respiratory Symptoms and Lung Function Decline: The ARIC Study
    Mirabelli, Maria C. ;
    London, Stephanie J.
    2012/03/20 | Respir Res 2012 Mar; 13:24 | National Institute for Occupational Safety and Health (NIOSH)
    Background: Specific occupations are associated with adverse respiratory health. Inhalation exposures encountered in these jobs may place workers at risk of new-onset respiratory disease. Methods: We analyzed data from 8,967 participants from the Atherosclerosis Risk in Communities (ARIC) study, a longitudinal cohort study. Participants included in ...
    Supporting Files
  • Factors limiting the transmission of HIV mutations conferring drug resistance fitness costs and genetic bottlenecks
    Factors limiting the transmission of HIV mutations conferring drug resistance: fitness costs and genetic bottlenecks
    Wagner, Bradley G. ;
    Garcia-Lerma, J. Gerardo
    Mar 19 2012 | Sci Rep. 2012; 2.
    Transmission of HIV strains with drug-resistance mutations (DRMs) causes public health problems in resource-rich countries. We use a stochastic model, with data from viral competition experiments, to analyze the effect of fitness costs (FCs) and genetic bottlenecks on limiting transmission of 10 clinically significant DRMs. Transmission of DRMs wit ...
    Supporting Files Public Domain
  • Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment
    Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment
    Mumtaz, Moiz ;
    Fisher, Jeffrey
    Mar 19 2012 | J Toxicol. 2012; 2012.
    Post-exposure risk assessment of chemical and environmental stressors is a public health challenge. Linking exposure to health outcomes is a 4-step process: exposure assessment, hazard identification, dose response assessment, and risk characterization. This process is increasingly adopting "in silico" tools such as physiologically based pharmacoki ...
    Supporting Files Public Domain
  • Molecular insights into the progression of crystalline silicainduced pulmonary toxicity in rats
    Molecular insights into the progression of crystalline silica-induced pulmonary toxicity in rats
    Sellamuthu, Rajendran ;
    Umbright, Christina
    Mar 19 2012 | J Appl Toxicol. 33(4):301-312.
    Identification of molecular target(s) and mechanism(s) of silica-induced pulmonary toxicity is important for the intervention and/or prevention of diseases associated with exposure to silica. Rats were exposed to crystalline silica by inhalation (15 mg m(-3), 6 h per day, 5 days) and global gene expression profile was determined in the lungs by mic ...
    Supporting Files
  • Update of the Case Definitions for PopulationBased Surveillance of Periodontitis
    Update of the Case Definitions for Population-Based Surveillance of Periodontitis
    Eke, Paul I. ;
    Page, Roy C.
    March 16 2012 | J Periodontol. 83(12):1449-1454
    BackgroundThis report adds a new definition for mild periodontitis that allows for better descriptions of the overall prevalence of periodontitis in populations. In 2007, the Centers for Disease Control and Prevention in partnership with the American Academy of Periodontology developed and reported standard case definitions for surveillance of mode ...
    Supporting Files
  • Proteomic changes at 8 weeks after infection are associated with chronic liver pathology in experimental schistosomiasis
    Proteomic changes at 8 weeks after infection are associated with chronic liver pathology in experimental schistosomiasis
    Manivannan, Bhagyashree ;
    Jordan, T. William
    3 16 2012 | J Proteomics. 75(6):1838-1848
    Chronic Schistosoma mansoni infection can present as a moderate or severe disease, termed intestinal or hepatosplenic schistosomiasis, respectively. Similarly, either moderate splenomegaly or hypersplenomegaly syndrome develops in CBA/J mice by 20weeks of infection and is similar to intestinal or hepatosplenic schistosomiasis respectively. Using th ...
    Supporting Files
  • Mutations in Polymerase Genes Enhanced the Virulence of 2009 Pandemic H1N1 Influenza Virus in Mice
    Mutations in Polymerase Genes Enhanced the Virulence of 2009 Pandemic H1N1 Influenza Virus in Mice
    Zhu, Wenfei ;
    Zhu, Yun
    Mar 15 2012 | PLoS One. 2012; 7(3).
    Influenza A virus can infect a wide variety of animal species with illness ranging from mild to severe, and is a continual cause for concern. Genetic mutations that occur either naturally or during viral adaptation in a poorly susceptible host are key mechanisms underlying the evolution and virulence of influenza A virus. Here, the variants contain ...
    Supporting Files Public Domain
  • Monitoring for Tuberculosis Drug Hepatotoxicity Moving from Opinion to Evidence
    Monitoring for Tuberculosis Drug Hepatotoxicity: Moving from Opinion to Evidence
    Saukkonen, Jussi J. ;
    Powell, Krista
    3 15 2012 | Am J Respir Crit Care Med. 185(6):598-599
    No Description
    Supporting Files
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