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Showing 301 - 320 of 1970 results

A Quantitative and Systematic Analysis of Anopheles Stephensi Bionomics and Control Approaches.

Mwema, Tabeth ;

Zohdy, Sarah

December 2024 | Acta Tropica, 2024, v. 260

Anopheles stephensi is a mosquito endemic to South Asia and the Arabian Peninsula that has recently been detected in eight African countries, posing a significant threat to global malaria control efforts. A challenge with An. stephensi is that it requires unique surveillance and control tools when compared to other malaria vectors. Through a system ...

10/10/2026

Supporting Files

Title : A Quantitative and Systematic Analysis of Anopheles Stephensi Bionomics and Control Approaches. Personal Author(s) : Mwema, Tabeth;Zohdy, Sarah;Sundaram, Mekala;Lepczyk, Christopher A.;Narine, Lana;Willoughby, Janna R.; Published Date : December 2024 Pages in Document : 107431 (19 pdf pages) Source : Acta Tropica, 2024, v. 260 DOI : https://doi.org/10.1016/j.actatropica.2024.107431 Journal Title : Acta Tropica
Mwema, T., Zohdy, S., Sundaram, M., Lepczyk, C. A., Narine, L., & Willoughby, J. R. (2024). A Quantitative and Systematic Analysis of Anopheles Stephensi Bionomics and Control Approaches. Acta Tropica, 260. https://doi.org/10.1016/j.actatropica.2024.107431

Mwema, Tabeth, Sarah Zohdy, Mekala Sundaram, Christopher A. Lepczyk, Lana Narine, and Janna R. Willoughby. "A Quantitative and Systematic Analysis of Anopheles Stephensi Bionomics and Control Approaches." Acta Tropica 260 (2024). https://doi.org/10.1016/j.actatropica.2024.107431.

Mwema, Tabeth, et al. "A Quantitative and Systematic Analysis of Anopheles Stephensi Bionomics and Control Approaches." Acta Tropica, vol. 260, 2024. Stacks. https://doi.org/10.1016/j.actatropica.2024.107431.
Export RIS Citation Information. TY - Journal Article AU - Mwema, Tabeth AU - Zohdy, Sarah AU - Sundaram, Mekala AU - Lepczyk, Christopher A. AU - Narine, Lana AU - Willoughby, Janna R. AB - Anopheles stephensi is a mosquito endemic to South Asia and the Arabian Peninsula that has recently been detected in eight African countries, posing a significant threat to global malaria control efforts. A challenge with An. stephensi is that it requires unique surveillance and control tools when compared to other malaria vectors. Through a systematic literature review, we investigated the efficacy of trapping methods and controls for An. stephensi mosquitoes, with a focus on studies of its behavior and biology. Data from 83 articles (native range: Afghanistan, India, Iran, Iraq, Pakistan, and Qatar; invasive range: Djibouti, Ethiopia, Sri Lanka, Saudi Arabia, and Sudan) met our study inclusion criteria. Data from these studies revealed that using host-seeking animal baited traps increased the number of mosquitoes collected per trap per day in the native range when compared to host-seeking human baited traps. However, these differences were not present in data collection rate assessments from the invasive range. We also found that An. stephensi equally used a large variety of breeding habitats in the native range, but that it tended to prefer water reservoirs and wastewater in the invasive range. Finally, we found that temephos, fenthion, Bacillus thuringiensis israelensis, and Beauveri bassiana were more effective at reducing larvae in their native range compared to the approaches found in our systematic literature search, but the relative effectiveness of these approaches in the invasive range was less clear. Understanding proven historical surveillance and control approaches is essential to the advancement of invasive An. stephensi mitigation efforts, but continued investigations in the invasive range are critical to reducing the impacts of malaria morbidity and mortality. AB - Author manuscript AN - cdc:261966 C4 - PMC11959532 DO - https://doi.org/10.1016/j.actatropica.2024.107431 J2 - Acta Tropica KW - Anopheles KW - Africa KW - Animals KW - Ecosystem KW - Introduced Species KW - Humans KW - Mosquito Control KW - Mosquito Vectors KW - Malaria KW - Insecticides KW - Malaria vector KW - Mosquito control KW - Invasive species KW - Anopheles KW - Animals KW - Mosquito Vectors KW - Mosquito Control KW - Malaria KW - Humans KW - Ecosystem KW - Africa KW - Introduced Species KW - Insecticides LA - eng PY - 2024 T2 - Acta Tropica T2 - Acta Tropica, 2024, v. 260 TI - A Quantitative and Systematic Analysis of Anopheles Stephensi Bionomics and Control Approaches. VL - 260 UR - https://stacks.cdc.gov/view/cdc/261966 ER -
Extending the Acute Skin Response Spectrum to Include the Far-UVC.

Gutierrez-Bayona, Natalia E. ;

Petersen, Camryn

May 16, 2025 | Photochemistry and Photobiology, 2025, v. 101, no. 3

Guidance on maximal limits for ultraviolet (UV) exposure has been developed by national and international organizations to protect against adverse effects on human skin and eyes. These guidelines consider the risk of both acute effects (i.e., erythema and photokeratitis) and delayed effects (e.g., skin and ocular cancers) when determining exposure ...

10/10/2026

Supporting Files

Title : Extending the Acute Skin Response Spectrum to Include the Far-UVC. Personal Author(s) : Gutierrez-Bayona, Natalia E.;Petersen, Camryn;Hashmi, Raabia H.;Buonanno, Manuela;Shuryak, Igor;Ponnaiya, Brian;Kleiman, Norman J.;Brenner, David J.;Welch, David; Published Date : May 16, 2025 Pages in Document : 673-682 (17 pdf pages) Source : Photochemistry and Photobiology, 2025, v. 101, no. 3 DOI : https://doi.org/10.1111/php.14035 Journal Title : Photochemistry and Photobiology
Gutierrez-Bayona, N. E., Petersen, C., Hashmi, R. H., Buonanno, M., Shuryak, I., Ponnaiya, B., Kleiman, N. J., Brenner, D. J., & Welch, D. (2025). Extending the Acute Skin Response Spectrum to Include the Far-UVC. Photochemistry and Photobiology, 101(3). https://doi.org/10.1111/php.14035

Gutierrez-Bayona, Natalia E., Camryn Petersen, Raabia H. Hashmi, Manuela Buonanno, Igor Shuryak, Brian Ponnaiya, Norman J. Kleiman, David J. Brenner, and David Welch. "Extending the Acute Skin Response Spectrum to Include the Far-UVC." Photochemistry and Photobiology 101, no. 3 (2025). https://doi.org/10.1111/php.14035.

Gutierrez-Bayona, Natalia E., et al. "Extending the Acute Skin Response Spectrum to Include the Far-UVC." Photochemistry and Photobiology, vol. 101, no. 3, 2025. Stacks. https://doi.org/10.1111/php.14035.
Export RIS Citation Information. TY - Journal Article AU - Gutierrez-Bayona, Natalia E. AU - Petersen, Camryn AU - Hashmi, Raabia H. AU - Buonanno, Manuela AU - Shuryak, Igor AU - Ponnaiya, Brian AU - Kleiman, Norman J. AU - Brenner, David J. AU - Welch, David AB - Guidance on maximal limits for ultraviolet (UV) exposure has been developed by national and international organizations to protect against adverse effects on human skin and eyes. These guidelines consider the risk of both acute effects (i.e., erythema and photokeratitis) and delayed effects (e.g., skin and ocular cancers) when determining exposure limits, and specify the dose a person can safely receive during an 8-h period without harmful effects. The determination of these exposure limits relies on the action spectra of photobiological responses triggered by UV radiation that quantify the effectiveness of each wavelength at eliciting each of these effects. With growing interest in using far-UVC (200-235 nm) radiation to control the spread of airborne pathogens, recent arguments have emerged about revisiting exposure limits for UV wavelengths. However, the standard erythema action spectrum, which provides some of the quantitative basis for these limits, has not been extended below 240 nm. This study assists to expand the erythema action spectrum to far-UVC wavelengths using a hairless albino mice model. We estimate that inducing acute effects on mouse skin with 222 nm radiation requires a dose of 1162 mJ/cm AB - , well above the current ACGIH skin exposure limit of 480 mJ/cm AB - . AB - Author manuscript AN - cdc:261965 C4 - PMC12019814 DO - https://doi.org/10.1111/php.14035 IS - 3 J2 - Photochemistry and Photobiology KW - Skin KW - Animals KW - Ultraviolet Rays KW - Humans KW - Mice, Hairless KW - Erythema KW - Mice KW - acute effects KW - far-UVC KW - skin safety KW - far‐UVC KW - Ultraviolet Rays KW - Animals KW - Skin KW - Mice KW - Erythema KW - Humans KW - Mice, Hairless LA - eng PY - 2025 T2 - Photochemistry and Photobiology T2 - Photochemistry and Photobiology, 2025, v. 101, no. 3 TI - Extending the Acute Skin Response Spectrum to Include the Far-UVC. VL - 101 UR - https://stacks.cdc.gov/view/cdc/261965 ER -
Summarizing Recommendations For the Prevention of Occupational Heat-Related Illness in Outdoor Workers: a Scoping Review.

Edgerly, Ashley ;

Lee Gillespie, Gordon

February 2025 | Workplace Health & Safety, 2025, v. 73, no. 2

Outdoor workers face unique challenges in preventing heat-related illnesses (HRI). Although preventable, HRI and death from heat exposure continue. A review of the most recent recommendation for HRI prevention in outdoor workers in the United States was warranted. A scoping review using PRISMA guidelines was conducted to compile policy statements a ...

10/10/2026

Supporting Files

Title : Summarizing Recommendations For the Prevention of Occupational Heat-Related Illness in Outdoor Workers: a Scoping Review. Personal Author(s) : Edgerly, Ashley;Lee Gillespie, Gordon;Bhattacharya, Amit;Hittle, Beverly M.; Published Date : February 2025 Pages in Document : 63-84 (38 pdf pages) Source : Workplace Health & Safety, 2025, v. 73, no. 2 DOI : https://doi.org/10.1177/21650799241281998 Journal Title : Workplace Health & Safety
Edgerly, A., Lee Gillespie, G., Bhattacharya, A., & Hittle, B. M. (2025). Summarizing Recommendations For the Prevention of Occupational Heat-Related Illness in Outdoor Workers: a Scoping Review. Workplace Health & Safety, 73(2). https://doi.org/10.1177/21650799241281998

Edgerly, Ashley, Gordon Lee Gillespie, Amit Bhattacharya, and Beverly M. Hittle. "Summarizing Recommendations For the Prevention of Occupational Heat-Related Illness in Outdoor Workers: a Scoping Review." Workplace Health & Safety 73, no. 2 (2025). https://doi.org/10.1177/21650799241281998.

Edgerly, Ashley, et al. "Summarizing Recommendations For the Prevention of Occupational Heat-Related Illness in Outdoor Workers: a Scoping Review." Workplace Health & Safety, vol. 73, no. 2, 2025. Stacks. https://doi.org/10.1177/21650799241281998.
Export RIS Citation Information. TY - Journal Article AU - Edgerly, Ashley AU - Lee Gillespie, Gordon AU - Bhattacharya, Amit AU - Hittle, Beverly M. AB - Outdoor workers face unique challenges in preventing heat-related illnesses (HRI). Although preventable, HRI and death from heat exposure continue. A review of the most recent recommendation for HRI prevention in outdoor workers in the United States was warranted. A scoping review using PRISMA guidelines was conducted to compile policy statements and recommendations on the prevention of HRI and synthesize them into a three-step plan for prevention using the Haddon Matrix. AB - PubMed, CINAHL, Medline, and websites from organizations and regulating bodies were searched for sources. Key terms such as occupational OR workers OR employers OR policymakers, HRI OR heat stress OR heat, prevention, recommendations OR position statements were used. Inclusion criteria were articles published within the last 5 years written in English and containing recommendations for preventing HRI in outdoor workers. Research not based on U.S. workers was excluded from the review. AB - Twenty sources comprised the review. Several themes emerged, indicating deficient recommendations for secondary and tertiary prevention. AB - This review's findings can be used by occupational health nurses (OHNs) in developing comprehensive interventions for preventing HRI and injury, using clear language, and following evidenced-based practices to increase workplace health and safety and promote equity. AB - Author manuscript AN - cdc:261964 C4 - PMC12101872 DO - https://doi.org/10.1177/21650799241281998 IS - 2 J2 - Workplace Health & Safety KW - Occupational Diseases KW - Occupational Exposure KW - Occupational Health Nursing KW - Heat Stress Disorders KW - Humans KW - Occupational Health KW - Workplace KW - occupational heat-related illness KW - prevention KW - recommendations KW - farmworkers KW - occupational health nurse KW - Humans KW - Heat Stress Disorders KW - Occupational Diseases KW - Occupational Exposure KW - Occupational Health KW - Occupational Health Nursing KW - Workplace LA - eng PY - 2025 T2 - Workplace Health & Safety T2 - Workplace Health & Safety, 2025, v. 73, no. 2 TI - Summarizing Recommendations For the Prevention of Occupational Heat-Related Illness in Outdoor Workers: a Scoping Review. VL - 73 UR - https://stacks.cdc.gov/view/cdc/261964 ER -
HIV Retesting Among People Living With HIV in Lesotho in 2022.

Pogue, Spencer D ;

Saito, Suzue

February 2025 | International Journal of STD & AIDS, 2025, v. 36, no. 2

Despite widespread HIV testing in sub-Saharan Africa, regular testing among at-risk populations is crucial for effective prevention. However, reports increasingly indicate retesting among people living with HIV (PLHIV), a group that would not require additional testing since they would already have received a confirmed diagnosis. We describe the de ...

10/10/2026

Supporting Files

Title : HIV Retesting Among People Living With HIV in Lesotho in 2022. Personal Author(s) : Pogue, Spencer D;Saito, Suzue;Tlhomola, Mphotleng;West, Christine A;Asiimwe, Fred;Ramphalla, Puleng;Poirot, Eugenie;Steiner, Claire;Greenleaf, Abigail R; Published Date : February 2025 Pages in Document : 114-118 (9 pdf pages) Source : International Journal of STD & AIDS, 2025, v. 36, no. 2 DOI : https://doi.org/10.1177/09564624241289984 Journal Title : International Journal of STD & AIDS
Pogue, S. D., Saito, S., Tlhomola, M., West, C. A., Asiimwe, F., Ramphalla, P., Poirot, E., Steiner, C., & Greenleaf, A. R. (2025). HIV Retesting Among People Living With HIV in Lesotho in 2022. International Journal of STD & AIDS, 36(2). https://doi.org/10.1177/09564624241289984

Pogue, Spencer D, Suzue Saito, Mphotleng Tlhomola, Christine A West, Fred Asiimwe, Puleng Ramphalla, Eugenie Poirot, Claire Steiner, and Abigail R Greenleaf. "HIV Retesting Among People Living With HIV in Lesotho in 2022." International Journal of STD & AIDS 36, no. 2 (2025). https://doi.org/10.1177/09564624241289984.

Pogue, Spencer D, et al. "HIV Retesting Among People Living With HIV in Lesotho in 2022." International Journal of STD & AIDS, vol. 36, no. 2, 2025. Stacks. https://doi.org/10.1177/09564624241289984.
Export RIS Citation Information. TY - Journal Article AU - Pogue, Spencer D AU - Saito, Suzue AU - Tlhomola, Mphotleng AU - West, Christine A AU - Asiimwe, Fred AU - Ramphalla, Puleng AU - Poirot, Eugenie AU - Steiner, Claire AU - Greenleaf, Abigail R AB - Despite widespread HIV testing in sub-Saharan Africa, regular testing among at-risk populations is crucial for effective prevention. However, reports increasingly indicate retesting among people living with HIV (PLHIV), a group that would not require additional testing since they would already have received a confirmed diagnosis. We describe the demographic characteristics of PLHIV retesters in Lesotho, report the average number of HIV tests post-diagnosis among PLHIV, and share motivations for retesting. AB - In August 2022, a nationally representative cohort in Lesotho participated in a cell phone survey about their HIV status and testing history. Study participants were recruited from a face-to-face survey conducted in 2020, Lesotho Population Based HIV Impact Assessment survey. AB - Of the 1523 participants called, 1111 participants responded (72.9%) and 266 reported living with HIV. We found 18.8% of people living with HIV (PLHIV) reported retesting at least once for HIV, and 58% of PLHIV who reported retesting were likely or very likely to retest for HIV in the coming year. The main reason PLHIV reported retesting was because a health care worker offered the test (61.7%) followed by self-initiated testing to confirm their status (29.1%). Among male PLHIV who had a history of retesting, 92.0% were very likely or likely to retest, compared to only 30.6% of female PLHIV. AB - We found almost a fifth of PLHIV in Lesotho reported a history of retesting for HIV, and 58% of PLHIV were likely or very likely to retest for HIV in the coming year. Educating providers and men living with HIV could reduce retesting among PLHIV. AB - Author manuscript AN - cdc:261963 C4 - PMC11844745 DO - https://doi.org/10.1177/09564624241289984 IS - 2 J2 - International Journal of STD & AIDS KW - Adolescent KW - Female KW - Surveys and Questionnaires KW - HIV Testing KW - Mass Screening KW - Male KW - Humans KW - Middle Aged KW - Young Adult KW - Adult KW - HIV Infections KW - HIV KW - testing KW - sub-Saharan Africa KW - cell phone survey KW - surveillance KW - Lesotho KW - Humans KW - Male KW - HIV Infections KW - Female KW - Adult KW - Middle Aged KW - Surveys and Questionnaires KW - HIV Testing KW - Mass Screening KW - Young Adult KW - Adolescent LA - eng PY - 2025 T2 - International Journal of STD & AIDS T2 - International Journal of STD & AIDS, 2025, v. 36, no. 2 TI - HIV Retesting Among People Living With HIV in Lesotho in 2022. VL - 36 UR - https://stacks.cdc.gov/view/cdc/261963 ER -
Assessing Older Adults' Readiness For Adopting Fall Prevention Recommendations Using the Transtheoretical Stages of Change.

Mark, Janice A. ;

Henry, Ankita

May 2025 | Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society, 2025, v. 44, no. 5

Reducing fall risk requires older adults (age 65+) to adopt effective prevention strategies. This study has three aims: 1) understand Stage of Change (SOC) for three fall prevention strategies; 2) determine strategies older adults' use; and 3) understand which characteristics relate to readiness to take action.A survey of 1063 older adults assessed ...

10/10/2026

Supporting Files

Title : Assessing Older Adults' Readiness For Adopting Fall Prevention Recommendations Using the Transtheoretical Stages of Change. Personal Author(s) : Mark, Janice A.;Henry, Ankita;Moreland, Briana;Dobash, Dawson;Bergen, Gwen; Published Date : May 2025 Pages in Document : 726-736 (20 pdf pages) Source : Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society, 2025, v. 44, no. 5 DOI : https://doi.org/10.1177/07334648241289933 Journal Title : Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society
Mark, J. A., Henry, A., Moreland, B., Dobash, D., & Bergen, G. (2025). Assessing Older Adults' Readiness For Adopting Fall Prevention Recommendations Using the Transtheoretical Stages of Change. Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society, 44(5). https://doi.org/10.1177/07334648241289933

Mark, Janice A., Ankita Henry, Briana Moreland, Dawson Dobash, and Gwen Bergen. "Assessing Older Adults' Readiness For Adopting Fall Prevention Recommendations Using the Transtheoretical Stages of Change." Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society 44, no. 5 (2025). https://doi.org/10.1177/07334648241289933.

Mark, Janice A., et al. "Assessing Older Adults' Readiness For Adopting Fall Prevention Recommendations Using the Transtheoretical Stages of Change." Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society, vol. 44, no. 5, 2025. Stacks. https://doi.org/10.1177/07334648241289933.
Export RIS Citation Information. TY - Journal Article AU - Mark, Janice A. AU - Henry, Ankita AU - Moreland, Briana AU - Dobash, Dawson AU - Bergen, Gwen AB - Reducing fall risk requires older adults (age 65+) to adopt effective prevention strategies. This study has three aims: 1) understand Stage of Change (SOC) for three fall prevention strategies; 2) determine strategies older adults' use; and 3) understand which characteristics relate to readiness to take action. AB - A survey of 1063 older adults assessed fall risk, SOC, and use of fall prevention strategies. Data analysis included descriptive statistics and regression analysis. AB - The most common SOC for older adults by strategy was AB - for overall fall prevention (61%), AB - for medication management (45%), and AB - and AB - for strength/balance (29% each). Believing falls are preventable was most strongly related to being in a AB - stage (e.g., AB - ) for overall fall prevention (Risk Ratio: 1.4, 95% CI: 1.1, 1.7). AB - Health promotion can focus on increasing knowledge of evidence-based fall prevention strategies to encourage older adults to take action. AB - Author manuscript AN - cdc:261962 C4 - PMC12012151 DO - https://doi.org/10.1177/07334648241289933 IS - 5 J2 - Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society KW - Aged, 80 and over KW - Health Knowledge, Attitudes, Practice KW - Geriatric Assessment KW - Surveys and Questionnaires KW - Female KW - Risk Assessment KW - Male KW - Aged KW - Accidental Falls KW - Humans KW - strength and balance KW - exercise KW - medication KW - unintentional falls KW - older adults KW - Humans KW - Accidental Falls KW - Aged KW - Female KW - Male KW - Aged, 80 and over KW - Surveys and Questionnaires KW - Health Knowledge, Attitudes, Practice KW - Risk Assessment KW - Geriatric Assessment LA - eng PY - 2025 T2 - Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society T2 - Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society, 2025, v. 44, no. 5 TI - Assessing Older Adults' Readiness For Adopting Fall Prevention Recommendations Using the Transtheoretical Stages of Change. VL - 44 UR - https://stacks.cdc.gov/view/cdc/261962 ER -
Hypertonic Saline Nasal Rinse Intervention: Immunomodulatory Effects in Dairy Workers.

Erlandson, Grant ;

Magzamen, Sheryl

January 2025 | Journal of Agromedicine, 2025, v. 30, no. 1

Increased risk of occupational exposure to bioaerosols has long been recognized in livestock operations including dairy facilities. Spanning the inhalable fraction (0-100 μm), dairy bioaerosols comprise a wide variety of inflammatory components that deposit in the nasopharyngeal region. The resultant inflammatory response from bioaerosol exposure i ...

10/10/2026

Supporting Files

Title : Hypertonic Saline Nasal Rinse Intervention: Immunomodulatory Effects in Dairy Workers. Personal Author(s) : Erlandson, Grant;Magzamen, Sheryl;Sharp, Julia L.;Seidel, James;Poole, Jill A.;Bradford, Mary;Schaeffer, Joshua W.; Published Date : January 2025 Pages in Document : 27-37 (21 pdf pages) Source : Journal of Agromedicine, 2025, v. 30, no. 1 DOI : https://doi.org/10.1080/1059924X.2024.2416425 Journal Title : Journal of Agromedicine
Erlandson, G., Magzamen, S., Sharp, J. L., Seidel, J., Poole, J. A., Bradford, M., & Schaeffer, J. W. (2025). Hypertonic Saline Nasal Rinse Intervention: Immunomodulatory Effects in Dairy Workers. Journal of Agromedicine, 30(1). https://doi.org/10.1080/1059924X.2024.2416425

Erlandson, Grant, Sheryl Magzamen, Julia L. Sharp, James Seidel, Jill A. Poole, Mary Bradford, and Joshua W. Schaeffer. "Hypertonic Saline Nasal Rinse Intervention: Immunomodulatory Effects in Dairy Workers." Journal of Agromedicine 30, no. 1 (2025). https://doi.org/10.1080/1059924X.2024.2416425.

Erlandson, Grant, et al. "Hypertonic Saline Nasal Rinse Intervention: Immunomodulatory Effects in Dairy Workers." Journal of Agromedicine, vol. 30, no. 1, 2025. Stacks. https://doi.org/10.1080/1059924X.2024.2416425.
Export RIS Citation Information. TY - Journal Article AU - Erlandson, Grant AU - Magzamen, Sheryl AU - Sharp, Julia L. AU - Seidel, James AU - Poole, Jill A. AU - Bradford, Mary AU - Schaeffer, Joshua W. AB - Increased risk of occupational exposure to bioaerosols has long been recognized in livestock operations including dairy facilities. Spanning the inhalable fraction (0-100 μm), dairy bioaerosols comprise a wide variety of inflammatory components that deposit in the nasopharyngeal region. The resultant inflammatory response from bioaerosol exposure is likely driving the increased prevalence of respiratory disease observed in dairy workers. It is also thought the microbiome of the upper respiratory system may help mediate this inflammation. We investigated the viability of a low-cost hypertonic saline nasal rinse intervention in modulating inflammatory responses in bioaerosol exposed dairy workers and its impact on microbial diversity. AB - Pre- and post-shift nasal rinses were administered and collected alongside full shift inhalable personal breathing zone (PBZ) samples for each participant for up to 5 consecutive days. Treatment group participants ( AB - = 23) received hypertonic saline rinses while control group participants ( AB - = 22) received normotonic saline rinses. Particulate matter (PM) and endotoxin concentrations were quantified from PBZ samples using gravimetric and enzymatic analytical methods, respectively. Pre- and post-shift rinses were analyzed for pro- and anti-inflammatory markers and microbial diversity using a multiplex assay and 16S rRNA sequencing, respectively. AB - PM and endotoxin concentrations were comparable between groups indicating similar exposures. Post-shift pro-inflammatory markers were significantly higher than pre-shift for IL-13 ( AB - = .047), IL-1β ( AB - < .001), IL-6 ( AB - < .001), IL-8 ( AB - < .001), and TNF-α ( AB - = .024). There was no evidence of a difference in log concentrations between intervention group or day among any of the measured inflammatory markers. Anti-inflammatory IL-10 concentrations increased across the 5 sample days, independent of treatment group suggesting tonicity may not be driving the change. However, this result was not significant ( AB - = .217). Nasal microbiome alpha (within sample) and beta (between sample) diversity metrics did not differ significantly between group or day demonstrating no adverse washout intervention effects. AB - This study provided encouraging results that warrant future research to further evaluate saline nasal rinses as a workplace intervention. AB - Author manuscript AN - cdc:261961 C4 - PMC12165301 DO - https://doi.org/10.1080/1059924X.2024.2416425 IS - 1 J2 - Journal of Agromedicine KW - Occupational Exposure KW - Aerosols KW - Female KW - Microbiota KW - Saline Solution, Hypertonic KW - Particulate Matter KW - Dairying KW - Endotoxins KW - Nasal Lavage KW - Male KW - Humans KW - Middle Aged KW - Adult KW - Agricultural health KW - bioaerosols KW - intervention KW - inflammation KW - nasal lavage KW - Humans KW - Saline Solution, Hypertonic KW - Occupational Exposure KW - Female KW - Adult KW - Dairying KW - Male KW - Particulate Matter KW - Aerosols KW - Endotoxins KW - Microbiota KW - Middle Aged KW - Nasal Lavage LA - eng PY - 2025 T2 - Journal of Agromedicine T2 - Journal of Agromedicine, 2025, v. 30, no. 1 TI - Hypertonic Saline Nasal Rinse Intervention: Immunomodulatory Effects in Dairy Workers. VL - 30 UR - https://stacks.cdc.gov/view/cdc/261961 ER -
A Qualitative Assessment of Changes in Occupational Exposures Among Healthcare Facility Workers.

de Porras, David Gimeno Ruiz ;

Patel, Jenil

February 2025 | Workplace Health & Safety, 2025, v. 73, no. 2

Adult-onset asthma, notably prevalent among healthcare professionals, especially nurses, is often attributed to occupational factors such as exposure to cleaning agents. Studies consistently underscore the substantial role of such exposure in work-related asthma among hospital staff. We aimed to (a) identify and characterize current practices in cl ...

10/10/2026

Supporting Files

Title : A Qualitative Assessment of Changes in Occupational Exposures Among Healthcare Facility Workers. Personal Author(s) : de Porras, David Gimeno Ruiz;Patel, Jenil;Conway, Sadie;Pompeii, Lisa;Mitchell, Laura E.;Carson, Arch;Whitehead, Lawrence W.;Han, Inkyu;Zock, Jan-Paul;Henneberger, Paul K.;Patel, Riddhi;De Los Reyes, Joy;Delclos, George L.; Published Date : February 2025 Pages in Document : 53-62 (17 pdf pages) Source : Workplace Health & Safety, 2025, v. 73, no. 2 DOI : https://doi.org/10.1177/21650799241284085 Journal Title : Workplace Health & Safety
de Porras, D. G. R., Patel, J., Conway, S., Pompeii, L., Mitchell, L. E., Carson, A., Whitehead, L. W., Han, I., Zock, J. P., Henneberger, P. K., Patel, R., De Los Reyes, J., & Delclos, G. L. (2025). A Qualitative Assessment of Changes in Occupational Exposures Among Healthcare Facility Workers. Workplace Health & Safety, 73(2). https://doi.org/10.1177/21650799241284085

de Porras, David Gimeno Ruiz, Jenil Patel, Sadie Conway, Lisa Pompeii, Laura E. Mitchell, Arch Carson, and Lawrence W. Whitehead, et al.. "A Qualitative Assessment of Changes in Occupational Exposures Among Healthcare Facility Workers." Workplace Health & Safety 73, no. 2 (2025). https://doi.org/10.1177/21650799241284085.

de Porras, David Gimeno Ruiz, et al. "A Qualitative Assessment of Changes in Occupational Exposures Among Healthcare Facility Workers." Workplace Health & Safety, vol. 73, no. 2, 2025. Stacks. https://doi.org/10.1177/21650799241284085.
Export RIS Citation Information. TY - Journal Article AU - de Porras, David Gimeno Ruiz AU - Patel, Jenil AU - Conway, Sadie AU - Pompeii, Lisa AU - Mitchell, Laura E. AU - Carson, Arch AU - Whitehead, Lawrence W. AU - Han, Inkyu AU - Zock, Jan-Paul AU - Henneberger, Paul K. AU - Patel, Riddhi AU - De Los Reyes, Joy AU - Delclos, George L. AB - Adult-onset asthma, notably prevalent among healthcare professionals, especially nurses, is often attributed to occupational factors such as exposure to cleaning agents. Studies consistently underscore the substantial role of such exposure in work-related asthma among hospital staff. We aimed to (a) identify and characterize current practices in cleaning and aerosolized medication administration; (b) assess changes in practices since a similar 2003 study of Texas healthcare workers; and (c) identify factors contributing to diverse exposures within healthcare job categories. We conducted focus groups with 38 participants in 6 healthcare settings, analyzing current practices, changes since 2003, and factors contributing to exposure diversity. We used a three-step approach for data analysis, including sociodemographic characterization, a scissor-and-sort technique for exposure description, and qualitative content analysis. Participants were primarily healthcare providers (76%) and housekeepers/cleaners (11%) who reported exposure to aerosolized medications, cleaning products, adhesives, and solvents. Participants reported transitioning from cleaning practices to new formulas with reduced odors and shifting from spray cleansers to wipes. Personal protective equipment (PPE) used during cleaning tasks varied, with training differing among job categories. Aerosolized medication administration varied among facilities, with reported medication types and protocol changes over time. The results emphasized the significance of maintaining uniform protection, disseminating knowledge, and consistently adhering to PPE protocols in the healthcare environment. Addressing the identified gaps in comprehension and potential sources of exposure variability requires additional focus on occupational health and safety initiatives. AB - Author manuscript AN - cdc:261960 C4 - PMC11774666 DO - https://doi.org/10.1177/21650799241284085 IS - 2 J2 - Workplace Health & Safety KW - Occupational Exposure KW - Focus Groups KW - Female KW - Qualitative Research KW - Asthma KW - Male KW - Middle Aged KW - Humans KW - Health Personnel KW - Personal Protective Equipment KW - Health Facilities KW - Adult KW - qualitative research methods KW - occupational health KW - respiratory conditions/asthma KW - employee health KW - workplace hazards KW - Humans KW - Occupational Exposure KW - Adult KW - Female KW - Male KW - Focus Groups KW - Middle Aged KW - Qualitative Research KW - Health Personnel KW - Personal Protective Equipment KW - Asthma KW - Health Facilities LA - eng PY - 2025 T2 - Workplace Health & Safety T2 - Workplace Health & Safety, 2025, v. 73, no. 2 TI - A Qualitative Assessment of Changes in Occupational Exposures Among Healthcare Facility Workers. VL - 73 UR - https://stacks.cdc.gov/view/cdc/261960 ER -
Comparative Safety of Different Antibiotic Regimens For the Treatment of Outpatient Community-Acquired Pneumonia Among Otherwise Healthy Adults.

Butler, Anne M. ;

Nickel, Katelin B.

February 2026 | Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 2026, v. 81, no. 6

Evidence is limited on the comparative safety of antibiotic regimens for treatment of community-acquired pneumonia (CAP). We compared the risk of adverse drug events (ADEs) associated with antibiotic regimens for CAP treatment among otherwise healthy, nonelderly adults.We conducted an active-comparator new-user cohort study (2007-2019) of commercia ...

10/10/2026

Supporting Files

Title : Comparative Safety of Different Antibiotic Regimens For the Treatment of Outpatient Community-Acquired Pneumonia Among Otherwise Healthy Adults. Personal Author(s) : Butler, Anne M.;Nickel, Katelin B.;Olsen, Margaret A.;Sahrmann, John M.;Colvin, Ryan;Neuner, Elizabeth;O'Neil, Caroline A.;Fraser, Victoria J.;Durkin, Michael J.; Published Date : February 2026 Pages in Document : 1141-1151 (18 pdf pages) Source : Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 2026, v. 81, no. 6 DOI : https://doi.org/10.1093/cid/ciae519 Journal Title : Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America
Butler, A. M., Nickel, K. B., Olsen, M. A., Sahrmann, J. M., Colvin, R., Neuner, E., O'Neil, C. A., Fraser, V. J., & Durkin, M. J. (2026). Comparative Safety of Different Antibiotic Regimens For the Treatment of Outpatient Community-Acquired Pneumonia Among Otherwise Healthy Adults. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 81(6). https://doi.org/10.1093/cid/ciae519

Butler, Anne M., Katelin B. Nickel, Margaret A. Olsen, John M. Sahrmann, Ryan Colvin, Elizabeth Neuner, Caroline A. O'Neil, Victoria J. Fraser, and Michael J. Durkin. "Comparative Safety of Different Antibiotic Regimens For the Treatment of Outpatient Community-Acquired Pneumonia Among Otherwise Healthy Adults." Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America 81, no. 6 (2026). https://doi.org/10.1093/cid/ciae519.

Butler, Anne M., et al. "Comparative Safety of Different Antibiotic Regimens For the Treatment of Outpatient Community-Acquired Pneumonia Among Otherwise Healthy Adults." Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, vol. 81, no. 6, 2026. Stacks. https://doi.org/10.1093/cid/ciae519.
Export RIS Citation Information. TY - Journal Article AU - Butler, Anne M. AU - Nickel, Katelin B. AU - Olsen, Margaret A. AU - Sahrmann, John M. AU - Colvin, Ryan AU - Neuner, Elizabeth AU - O'Neil, Caroline A. AU - Fraser, Victoria J. AU - Durkin, Michael J. AB - Evidence is limited on the comparative safety of antibiotic regimens for treatment of community-acquired pneumonia (CAP). We compared the risk of adverse drug events (ADEs) associated with antibiotic regimens for CAP treatment among otherwise healthy, nonelderly adults. AB - We conducted an active-comparator new-user cohort study (2007-2019) of commercially insured adults aged 18-64 years diagnosed with outpatient CAP, evaluated via chest X-ray, and dispensed a same-day CAP-related oral antibiotic regimen. ADE follow-up duration ranged from 2 to 90 days (eg, renal failure [14 days]). We estimated risk differences [RDs] per 1000 treatment episodes and risk ratios using propensity score-weighted Kaplan-Meier functions. Ankle/knee sprain and influenza vaccination were considered as negative control outcomes. AB - Of 145 137 otherwise healthy CAP patients without comorbidities, 52% received narrow-spectrum regimens (44% macrolide, 8% doxycycline) and 48% received broad-spectrum regimens (39% fluoroquinolone, 7% β-lactam, 3% β-lactam + macrolide). Compared with macrolide monotherapy, each broad-spectrum antibiotic regimen was associated with increased risk of several ADEs (eg, β-lactam: nausea/vomiting/abdominal pain [RD per 1000, 3.20; 95% CI, 0.99-5.73]; non-Clostridioides difficile diarrhea [RD per 1000, 4.61; 95% CI, 2.47-6.82]; vulvovaginal candidiasis/vaginitis [RD per 1000, 3.57; 95% CI, 0.87, 6.88]). Narrow-spectrum antibiotic regimens largely conferred similar risk of ADEs. We generally observed similar risks of each negative control outcome, indicating minimal confounding. AB - Broad-spectrum antibiotics were associated with increased risk of ADEs among otherwise healthy adults treated for CAP in the outpatient setting. Antimicrobial stewardship is needed to promote judicious use of broad-spectrum antibiotics and ultimately decrease antibiotic-related ADEs. AB - Author manuscript AN - cdc:261959 C4 - PMC12355227 DO - https://doi.org/10.1093/cid/ciae519 IS - 6 J2 - Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America KW - Outpatients KW - Adolescent KW - Pneumonia KW - Female KW - Macrolides KW - Young Adult KW - Cohort Studies KW - Male KW - Humans KW - Middle Aged KW - Anti-Bacterial Agents KW - Adult KW - Community-Acquired Pneumonia KW - Community-Acquired Infections KW - administrative data KW - adverse drug events KW - antibiotic safety KW - antimicrobial stewardship KW - community-acquired pneumonia KW - Humans KW - Community-Acquired Infections KW - Adult KW - Anti-Bacterial Agents KW - Female KW - Male KW - Middle Aged KW - Young Adult KW - Adolescent KW - Pneumonia KW - Outpatients KW - Cohort Studies KW - Macrolides KW - Community-Acquired Pneumonia LA - eng PY - 2026 T2 - Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America T2 - Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 2026, v. 81, no. 6 TI - Comparative Safety of Different Antibiotic Regimens For the Treatment of Outpatient Community-Acquired Pneumonia Among Otherwise Healthy Adults. VL - 81 UR - https://stacks.cdc.gov/view/cdc/261959 ER -
Implementation of a Peer-delivered Opioid Overdose Response Initiative in New York City Emergency Departments: Insight From Multi-stakeholder Qualitative Interviews.

Goldberg, Leah A. ;

Chang, Tingyee E.

January 2025 | Journal of Substance Use and Addiction Treatment, 2025, v. 168

Emergency departments (EDs) are critical touchpoints for overdose prevention efforts. In New York City (NYC), the Health Department's Relay initiative dispatches trained peer "Wellness Advocates" (WAs) to engage with patients in EDs after an overdose and for up to 90 days subsequently. Interest in peer-delivered interventions for patients at risk f ...

10/10/2026

Supporting Files

Title : Implementation of a Peer-delivered Opioid Overdose Response Initiative in New York City Emergency Departments: Insight From Multi-stakeholder Qualitative Interviews. Personal Author(s) : Goldberg, Leah A.;Chang, Tingyee E.;Freeman, Robin;Welch, Alice E.;Jeffers, Angela;Kepler, Kelsey L.;Chambless, Dominique;Wittman, Ian;Cowan, Ethan;Shelley, Donna;McNeely, Jennifer;Doran, Kelly M.; Published Date : January 2025 Pages in Document : 209542 (24 pdf pages) Source : Journal of Substance Use and Addiction Treatment, 2025, v. 168 DOI : https://doi.org/10.1016/j.josat.2024.209542 Journal Title : Journal of Substance Use and Addiction Treatment
Goldberg, L. A., Chang, T. E., Freeman, R., Welch, A. E., Jeffers, A., Kepler, K. L., Chambless, D., Wittman, I., Cowan, E., Shelley, D., McNeely, J., & Doran, K. M. (2025). Implementation of a Peer-delivered Opioid Overdose Response Initiative in New York City Emergency Departments: Insight From Multi-stakeholder Qualitative Interviews. Journal of Substance Use and Addiction Treatment, 168. https://doi.org/10.1016/j.josat.2024.209542

Goldberg, Leah A., Tingyee E. Chang, Robin Freeman, Alice E. Welch, Angela Jeffers, Kelsey L. Kepler, and Dominique Chambless, et al.. "Implementation of a Peer-delivered Opioid Overdose Response Initiative in New York City Emergency Departments: Insight From Multi-stakeholder Qualitative Interviews." Journal of Substance Use and Addiction Treatment 168 (2025). https://doi.org/10.1016/j.josat.2024.209542.

Goldberg, Leah A., et al. "Implementation of a Peer-delivered Opioid Overdose Response Initiative in New York City Emergency Departments: Insight From Multi-stakeholder Qualitative Interviews." Journal of Substance Use and Addiction Treatment, vol. 168, 2025. Stacks. https://doi.org/10.1016/j.josat.2024.209542.
Export RIS Citation Information. TY - Journal Article AU - Goldberg, Leah A. AU - Chang, Tingyee E. AU - Freeman, Robin AU - Welch, Alice E. AU - Jeffers, Angela AU - Kepler, Kelsey L. AU - Chambless, Dominique AU - Wittman, Ian AU - Cowan, Ethan AU - Shelley, Donna AU - McNeely, Jennifer AU - Doran, Kelly M. AB - Emergency departments (EDs) are critical touchpoints for overdose prevention efforts. In New York City (NYC), the Health Department's Relay initiative dispatches trained peer "Wellness Advocates" (WAs) to engage with patients in EDs after an overdose and for up to 90 days subsequently. Interest in peer-delivered interventions for patients at risk for overdose has grown nationally, but few studies have explored challenges and opportunities related to implementing such interventions in EDs. AB - We conducted in-depth interviews with Relay WAs, ED patients, and ED providers across 4 diverse NYC EDs. Sampling was purposeful and continued until theoretical saturation was reached. Interviews followed a semi-structured interview guide based on key domains from the Consolidated Framework for Implementation Research (CFIR). Interviews were conducted by telephone or web conferencing; audio recordings were professionally transcribed. The study utilized rapid qualitative analysis using template summaries and summary matrices followed by line-by-line coding conducted independently by 3 researchers, then discussed and harmonized at group coding meetings. Coding was both inductive (using an a priori code list based on CFIR domains and study goals) and deductive (new codes allowed to emerge from transcripts). Dedoose software was used for data organization. AB - We conducted 32 in-depth interviews (10 WAs, 12 patients, 10 ED providers). Four overarching themes emerged: 1) EDs are characterized by multiple competing demands (e.g., related to provider time and physical space), underscoring the utility of Relay and leading to some practical challenges for its delivery; 2) There is a strong role distinction of WAs as peers with lived experience; 3) ED providers value Relay, even though they have a limited understanding of its full scope and outcomes; 4) While the role of structural factors (e.g., homelessness and unstable housing) is recognized, responsibility is often placed on patients for controlling their own success. AB - We identified four themes that shed new light on the implementation of peer-based overdose prevention programs in EDs. Our findings highlight unique ED inner and outer setting factors that may impact program implementation and effectiveness. The findings provide actionable information to inform implementation of similar programs nationally. AB - Author manuscript AN - cdc:261958 C4 - PMC12177935 DO - https://doi.org/10.1016/j.josat.2024.209542 J2 - Journal of Substance Use and Addiction Treatment KW - Female KW - Peer Group KW - Opiate Overdose KW - Qualitative Research KW - Stakeholder Participation KW - Male KW - Humans KW - Middle Aged KW - Interviews as Topic KW - Emergency Service, Hospital KW - Adult KW - overdose KW - peer interventions KW - qualitative research KW - implementation research KW - emergency departments KW - Humans KW - Emergency Service, Hospital KW - Peer Group KW - Male KW - Female KW - Qualitative Research KW - Opiate Overdose KW - Adult KW - Interviews as Topic KW - Middle Aged KW - Stakeholder Participation LA - eng PY - 2025 T2 - Journal of Substance Use and Addiction Treatment T2 - Journal of Substance Use and Addiction Treatment, 2025, v. 168 TI - Implementation of a Peer-delivered Opioid Overdose Response Initiative in New York City Emergency Departments: Insight From Multi-stakeholder Qualitative Interviews. VL - 168 UR - https://stacks.cdc.gov/view/cdc/261958 ER -
Playful Activities Mitigate Relations Between Parental Mental Health Difficulties and Child Verbal Outcomes.

Nelson, Paige M. ;

Scheiber, Francesca

March 1, 2026 | Child Development, 2026, v. 96, no. 2

This study examined the role of parental involvement in the home learning environment in the association between parental mental health and child cognitive performance. In a sample of 174 three- to five-year-old children (52% female, 97% White, 7% Hispanic, 2019-2022), playful activities moderated the relation between parental general depression an ...

10/10/2026

Supporting Files

Title : Playful Activities Mitigate Relations Between Parental Mental Health Difficulties and Child Verbal Outcomes. Personal Author(s) : Nelson, Paige M.;Scheiber, Francesca;Laughlin, Haley M.;Demir-Lira, Ö. Ece; Published Date : March 1, 2026 Pages in Document : 562-576 (26 pdf pages) Source : Child Development, 2026, v. 96, no. 2 DOI : https://doi.org/10.1111/cdev.14187 Journal Title : Child Development
Nelson, P. M., Scheiber, F., Laughlin, H. M., & Demir-Lira, �. E. (2026). Playful Activities Mitigate Relations Between Parental Mental Health Difficulties and Child Verbal Outcomes. Child Development, 96(2). https://doi.org/10.1111/cdev.14187

Nelson, Paige M., Francesca Scheiber, Haley M. Laughlin, and Ö. Ece Demir-Lira. "Playful Activities Mitigate Relations Between Parental Mental Health Difficulties and Child Verbal Outcomes." Child Development 96, no. 2 (2026). https://doi.org/10.1111/cdev.14187.

Nelson, Paige M., et al. "Playful Activities Mitigate Relations Between Parental Mental Health Difficulties and Child Verbal Outcomes." Child Development, vol. 96, no. 2, 2026. Stacks. https://doi.org/10.1111/cdev.14187.
Export RIS Citation Information. TY - Journal Article AU - Nelson, Paige M. AU - Scheiber, Francesca AU - Laughlin, Haley M. AU - Demir-Lira, Ö. Ece AB - This study examined the role of parental involvement in the home learning environment in the association between parental mental health and child cognitive performance. In a sample of 174 three- to five-year-old children (52% female, 97% White, 7% Hispanic, 2019-2022), playful activities moderated the relation between parental general depression and child verbal reasoning and acquired verbal knowledge. However, there was no evidence that parental involvement moderated the association between parental mental health and child spatial reasoning. These results improve our understanding of the pathways by which parental mental health, even in a non-clinical community sample, relate to child outcomes and raise the possibility of leveraging playful activities as one mechanism to alleviate the potential role of parental mental health difficulties. AB - Author manuscript AN - cdc:261957 C4 - PMC11868687 DO - https://doi.org/10.1111/cdev.14187 IS - 2 J2 - Child Development KW - Parent-Child Relations KW - Female KW - Parents KW - Male KW - Humans KW - Parenting KW - Child, Preschool KW - Child Development KW - Child of Impaired Parents KW - Depression KW - Adult KW - Play and Playthings KW - Humans KW - Female KW - Male KW - Child, Preschool KW - Play and Playthings KW - Child of Impaired Parents KW - Depression KW - Adult KW - Parents KW - Parenting KW - Parent-Child Relations KW - Child Development LA - eng PY - 2026 T2 - Child Development T2 - Child Development, 2026, v. 96, no. 2 TI - Playful Activities Mitigate Relations Between Parental Mental Health Difficulties and Child Verbal Outcomes. VL - 96 UR - https://stacks.cdc.gov/view/cdc/261957 ER -
Atrial Cardiomyopathy Resulting From Loss of Plakophilin-2 Expression: Response to Adrenergic Stimulation and Implications For the Exercise Response.

Phadke, Kavya ;

D'Anna, Sergio

September 2025 | The Journal of Physiology, 2025, v. 603, no. 18

Atrial arrhythmias occur in 20-40% of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) and are associated with an increased risk of sustained ventricular arrhythmias and inappropriate implantable cardioverter-defibrillator shocks. The pathophysiology of atrial arrhythmias in ARVC remains unclear. Most cases of gene-positive ARVC ...

10/10/2026

Supporting Files

Title : Atrial Cardiomyopathy Resulting From Loss of Plakophilin-2 Expression: Response to Adrenergic Stimulation and Implications For the Exercise Response. Personal Author(s) : Phadke, Kavya;D'Anna, Sergio;Vega, Estefania Torres;Xiao, Junhua;Lin, Xianming;Zhang, Mingliang;Sall, Joseph;Liang, Feng-Xia;Park, David S.;Cerrone, Marina;Lundby, Alicia;Delmar, Mario;van Opbergen, Chantal J.M.; Published Date : September 2025 Pages in Document : 4951-4972 (38 pdf pages) Source : The Journal of Physiology, 2025, v. 603, no. 18 DOI : https://doi.org/10.1113/JP286985 Journal Title : The Journal of Physiology
Phadke, K., D'Anna, S., Vega, E. T., Xiao, J., Lin, X., Zhang, M., Sall, J., Liang, F. X., Park, D. S., Cerrone, M., Lundby, A., Delmar, M., & van Opbergen, C. J. (2025). Atrial Cardiomyopathy Resulting From Loss of Plakophilin-2 Expression: Response to Adrenergic Stimulation and Implications For the Exercise Response. The Journal of Physiology, 603(18). https://doi.org/10.1113/JP286985

Phadke, Kavya, Sergio D'Anna, Estefania Torres Vega, Junhua Xiao, Xianming Lin, Mingliang Zhang, and Joseph Sall, et al.. "Atrial Cardiomyopathy Resulting From Loss of Plakophilin-2 Expression: Response to Adrenergic Stimulation and Implications For the Exercise Response." The Journal of Physiology 603, no. 18 (2025). https://doi.org/10.1113/JP286985.

Phadke, Kavya, et al. "Atrial Cardiomyopathy Resulting From Loss of Plakophilin-2 Expression: Response to Adrenergic Stimulation and Implications For the Exercise Response." The Journal of Physiology, vol. 603, no. 18, 2025. Stacks. https://doi.org/10.1113/JP286985.
Export RIS Citation Information. TY - Journal Article AU - Phadke, Kavya AU - D'Anna, Sergio AU - Vega, Estefania Torres AU - Xiao, Junhua AU - Lin, Xianming AU - Zhang, Mingliang AU - Sall, Joseph AU - Liang, Feng-Xia AU - Park, David S. AU - Cerrone, Marina AU - Lundby, Alicia AU - Delmar, Mario AU - van Opbergen, Chantal J.M. AB - Atrial arrhythmias occur in 20-40% of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) and are associated with an increased risk of sustained ventricular arrhythmias and inappropriate implantable cardioverter-defibrillator shocks. The pathophysiology of atrial arrhythmias in ARVC remains unclear. Most cases of gene-positive ARVC are linked to pathogenic variants in the desmosomal gene plakophilin-2 (PKP2). Here, we test the hypothesis that loss of PKP2 expression leads to pro-arrhythmic changes in atrial cardiomyocytes. Atrial cells/tissue were obtained from a cardiac-specific, tamoxifen-activated model of PKP2 deficiency (PKP2cKO). By contrast to PKP2cKO ventricular myocytes, PKP2cKO atrial cardiomyocytes presented no significant differences in intracellular calcium (Ca AB - ) transient dynamics, sarcoplasmic reticulum load or action potential morphology. PKP2cKO atrial cardiomyocytes showed elevated reactive oxygen species levels, increased frequency and amplitude of Ca AB - sparks, and increased diastolic [Ca AB - ] AB - compared to control; the latter two parameters were further increased by isoproterenol exposure and reversed by exposure to ryanodine receptor blocker dantrolene. We speculate that these isoproterenol-dependent effects may impact on the exercise-related atrial arrhythmia risk in ARVC patients. Despite absence of changes in Ca AB - transient dynamics, PKP2cKO atrial cardiomyocytes showed enhanced sarcomere shortening and impaired sarcomere relaxation. Orthogonal transcriptomic analysis of human(GTEx) and PKP2cKO atrial tissue led to identification of 41 transcripts depending on PKP2 expression. Biochemical follow-up confirmed reduced abundance of sarcomeric protein myosin binding protein C, potentially playing a role in cellular shortening and relaxation changes observed. Our findings provide novel insights into the role of PKP2 in atrial myocardium with potential implications to therapeutic management of atrial fibrillation in patients with PKP2-related ARVC. KEY POINTS: Atrial arrhythmias occur in a large group of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), a cardiac disease mostly caused by pathogenic variants in the desmosomal gene plakophilin-2 (PKP2). Exercise is considered to be an independent risk factor for arrhythmias consequent to PKP2 deficiency. We show that loss of PKP2 expression affects cellular calcium handling and electrophysiology differently in left atrial vs. ventricular myocardium and causes extensive atrial fibrosis. PKP2-deficient atrial cardiomyocytes present increased spontaneous sarcoplasmic reticulum calcium release events, further enhanced by isoproterenol exposure and reversible by a ryanodine receptor blocker (dantrolene). In addition, PKP2-deficient atrial myocytes exhibit impaired relaxation and enhanced sarcomere shortening, most probably related to reduced abundance of myosin binding protein C. We speculate that cellular effects reported upon isoproterenol impact on the exercise-related atrial arrhythmia risk in ARVC patients. We further propose that therapeutic approaches aimed at mitigating ventricular damage may be effective to treat the atrial disease in ARVC. AB - Author manuscript AN - cdc:261956 C4 - PMC12018593 DO - https://doi.org/10.1113/JP286985 IS - 18 J2 - The Journal of Physiology KW - Sarcoplasmic Reticulum KW - Isoproterenol KW - Plakophilins KW - Arrhythmogenic Right Ventricular Dysplasia KW - Animals KW - Myocytes, Cardiac KW - Action Potentials KW - Exercise KW - Heart Atria KW - Reactive Oxygen Species KW - Male KW - Humans KW - Calcium KW - Mice KW - arrhythmogenic right ventricular cardiomyopathy KW - atrial fibrillation KW - plakophilin-2 KW - ryanodine receptor KW - oxidative stress KW - adrenergic stimulation KW - Plakophilins KW - Animals KW - Myocytes, Cardiac KW - Mice KW - Heart Atria KW - Male KW - Exercise KW - Isoproterenol KW - Calcium KW - Reactive Oxygen Species KW - Action Potentials KW - Humans KW - Arrhythmogenic Right Ventricular Dysplasia KW - Sarcoplasmic Reticulum LA - eng PY - 2025 T2 - The Journal of Physiology T2 - The Journal of Physiology, 2025, v. 603, no. 18 TI - Atrial Cardiomyopathy Resulting From Loss of Plakophilin-2 Expression: Response to Adrenergic Stimulation and Implications For the Exercise Response. VL - 603 UR - https://stacks.cdc.gov/view/cdc/261956 ER -
Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022-2023: a Prospective Cohort Study.

White, Elizabeth B. ;

Grant, Lauren

April 2025 | Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 80, no. 4

Previous estimates of vaccine effectiveness (VE) against asymptomatic influenza virus infection based on seroconversion have varied widely and may be biased. We estimated 2022-2023 influenza VE against illness and asymptomatic infection in a prospective cohort.In the HEROES-RECOVER cohort, adults at increased occupational risk of influenza exposure ...

10/10/2026

Supporting Files

Title : Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022-2023: a Prospective Cohort Study. Personal Author(s) : White, Elizabeth B.;Grant, Lauren;Mak, Josephine;Olsho, Lauren;Edwards, Laura J.;Naleway, Allison;Burgess, Jefferey L.;Ellingson, Katherine D.;Tyner, Harmony;Gaglani, Manjusha;Lutrick, Karen;Caban-Martinez, Alberto;Newes-Adeyi, Gabriella;Duque, Jazmin;Yoon, Sarang K.;Phillips, Andrew L.;Thompson, Mark;Britton, Amadea;Flannery, Brendan;Fowlkes, Ashley; Published Date : April 2025 Pages in Document : 893-900 (15 pdf pages) Source : Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 80, no. 4 DOI : https://doi.org/10.1093/cid/ciae491 Journal Title : Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
White, E. B., Grant, L., Mak, J., Olsho, L., Edwards, L. J., Naleway, A., Burgess, J. L., Ellingson, K. D., Tyner, H., Gaglani, M., Lutrick, K., Caban-Martinez, A., Newes-Adeyi, G., Duque, J., Yoon, S. K., Phillips, A. L., Thompson, M., Britton, A., Flannery, B., & Fowlkes, A. (2025). Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022-2023: a Prospective Cohort Study. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 80(4). https://doi.org/10.1093/cid/ciae491

White, Elizabeth B., Lauren Grant, Josephine Mak, Lauren Olsho, Laura J. Edwards, Allison Naleway, and Jefferey L. Burgess, et al.. "Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022-2023: a Prospective Cohort Study." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 80, no. 4 (2025). https://doi.org/10.1093/cid/ciae491.

White, Elizabeth B., et al. "Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022-2023: a Prospective Cohort Study." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, vol. 80, no. 4, 2025. Stacks. https://doi.org/10.1093/cid/ciae491.
Export RIS Citation Information. TY - Journal Article AU - White, Elizabeth B. AU - Grant, Lauren AU - Mak, Josephine AU - Olsho, Lauren AU - Edwards, Laura J. AU - Naleway, Allison AU - Burgess, Jefferey L. AU - Ellingson, Katherine D. AU - Tyner, Harmony AU - Gaglani, Manjusha AU - Lutrick, Karen AU - Caban-Martinez, Alberto AU - Newes-Adeyi, Gabriella AU - Duque, Jazmin AU - Yoon, Sarang K. AU - Phillips, Andrew L. AU - Thompson, Mark AU - Britton, Amadea AU - Flannery, Brendan AU - Fowlkes, Ashley AB - Previous estimates of vaccine effectiveness (VE) against asymptomatic influenza virus infection based on seroconversion have varied widely and may be biased. We estimated 2022-2023 influenza VE against illness and asymptomatic infection in a prospective cohort. AB - In the HEROES-RECOVER cohort, adults at increased occupational risk of influenza exposure across 7 US sites provided weekly symptom reports and nasal swabs for reverse transcription-polymerase chain reaction (RT-PCR) influenza testing. Laboratory-confirmed influenza virus infections were classified as symptomatic (≥1 symptom) or asymptomatic during the week of testing. Participants reported demographic information and vaccination through surveys; most sites verified vaccination through medical record and immunization registry review. Person-time was calculated as days from the site-specific influenza season start (September-October 2022) through date of infection, study withdrawal, or season end (May 2023). We compared influenza incidence among vaccinated versus unvaccinated participants overall, by symptom status, and by influenza A subtype, using Cox proportional hazards regression adjusted for site and occupation. We estimated VE as (1 - adjusted hazard ratio) × 100%. AB - In total, 269 of 3785 (7.1%) participants had laboratory-confirmed influenza, including 263 (98%) influenza A virus infections and 201 (75%) symptomatic illnesses. Incidence of laboratory-confirmed influenza illness among vaccinated versus unvaccinated participants was 23.7 and 33.2 episodes per 100 000 person-days, respectively (VE: 38%; 95% CI: 15%-55%). Incidence of asymptomatic influenza virus infection was 8.0 versus 11.6 per 100 000 (VE: 13%; 95% CI: -47%, 49%). AB - Vaccination reduced incidence of symptomatic but not asymptomatic influenza virus infection, suggesting that influenza vaccination attenuates progression from infection to illness. AB - Author manuscript AN - cdc:261955 C4 - PMC13289553 DO - https://doi.org/10.1093/cid/ciae491 IS - 4 J2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America KW - Influenza A virus KW - Female KW - Vaccination KW - Prospective Studies KW - Aged KW - Young Adult KW - Influenza Vaccines KW - Asymptomatic Infections KW - Incidence KW - Vaccine Efficacy KW - Male KW - Humans KW - Middle Aged KW - Adult KW - Influenza, Human KW - influenza KW - vaccines KW - cohort KW - asymptomatic infection KW - symptomatic illness KW - Humans KW - Influenza, Human KW - Influenza Vaccines KW - Prospective Studies KW - Male KW - Female KW - Middle Aged KW - Adult KW - Asymptomatic Infections KW - Vaccine Efficacy KW - Aged KW - Incidence KW - Vaccination KW - Young Adult KW - Influenza A virus LA - eng PY - 2025 T2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America T2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 80, no. 4 TI - Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022-2023: a Prospective Cohort Study. VL - 80 UR - https://stacks.cdc.gov/view/cdc/261955 ER -
New Mechanisms in Diisocyanate-mediated Allergy/toxicity: Are MicroRNAs in Play?

Lin, Chen-Chung ;

Law, Brandon F.

April 2025 | Current Opinion in Allergy and Clinical Immunology, 2025, v. 25, no. 2

To describe recent findings of diisocyanate-mediated mechanisms in allergy and toxicology by addressing the role of microRNA (miR) in immune responses that may contribute to the development of occupational asthma (OA).Studies of diisocyanate asthma have traditionally focused on the immune and inflammatory patterns associated with diisocyanate expos ...

10/10/2026

Supporting Files

Title : New Mechanisms in Diisocyanate-mediated Allergy/toxicity: Are MicroRNAs in Play? Personal Author(s) : Lin, Chen-Chung;Law, Brandon F.;Hettick, Justin M.; Published Date : April 2025 Pages in Document : 75-82 (13 pdf pages) Source : Current Opinion in Allergy and Clinical Immunology, 2025, v. 25, no. 2 DOI : https://doi.org/10.1097/ACI.0000000000001043 Journal Title : Current Opinion in Allergy and Clinical Immunology
Lin, C. C., Law, B. F., & Hettick, J. M. (2025). New Mechanisms in Diisocyanate-mediated Allergy/toxicity: Are MicroRNAs in Play?. Current Opinion in Allergy and Clinical Immunology, 25(2). https://doi.org/10.1097/ACI.0000000000001043

Lin, Chen-Chung, Brandon F. Law, and Justin M. Hettick. "New Mechanisms in Diisocyanate-mediated Allergy/toxicity: Are MicroRNAs in Play?." Current Opinion in Allergy and Clinical Immunology 25, no. 2 (2025). https://doi.org/10.1097/ACI.0000000000001043.

Lin, Chen-Chung, et al. "New Mechanisms in Diisocyanate-mediated Allergy/toxicity: Are MicroRNAs in Play?." Current Opinion in Allergy and Clinical Immunology, vol. 25, no. 2, 2025. Stacks. https://doi.org/10.1097/ACI.0000000000001043.
Export RIS Citation Information. TY - Journal Article AU - Lin, Chen-Chung AU - Law, Brandon F. AU - Hettick, Justin M. AB - To describe recent findings of diisocyanate-mediated mechanisms in allergy and toxicology by addressing the role of microRNA (miR) in immune responses that may contribute to the development of occupational asthma (OA). AB - Studies of diisocyanate asthma have traditionally focused on the immune and inflammatory patterns associated with diisocyanate exposures; however, recognized knowledge gaps exist regarding the detailed molecular mechanism(s) of pathogenesis. Recent studies demonstrate the critical role endogenous microRNAs play as gene regulators in maintaining homeostasis of the human body, and in the pathophysiology of many diseases including asthma. Given that diisocyanate-OA shares many pathophysiological characteristics with asthma, it is likely that miR-mediated mechanisms are involved in the pathophysiology of diisocyanate-OA. Recent reports have shown that changes in expression of endogenous miRs are associated with exposure to the occupationally relevant diisocyanates, toluene diisocyanate (TDI) and methylene diphenyl diisocyanate (MDI). Continued mechanistic study of these relevant miRs may lead to the development of novel biomarkers of occupational exposure and/or provide efficacious targets for therapeutic strategies in diisocyanate asthma. AB - The molecular mechanisms underlying diisocyanate-OA pathophysiology are heterogeneous and complicated. In this review, we highlight recent research into the roles and potential regulation of miRs in diisocyanate-OA. AB - Author manuscript AN - cdc:261954 C4 - PMC11867871 DO - https://doi.org/10.1097/ACI.0000000000001043 IS - 2 J2 - Current Opinion in Allergy and Clinical Immunology KW - Occupational Exposure KW - Toluene 2,4-Diisocyanate KW - Animals KW - Hypersensitivity KW - MicroRNAs KW - Isocyanates KW - Humans KW - Asthma, Occupational KW - 4,4'-methylene diphenyl diisocyanate KW - diisocyanates KW - microRNA KW - occupational asthma KW - toluene diisocyanate KW - Humans KW - MicroRNAs KW - Asthma, Occupational KW - Animals KW - Occupational Exposure KW - Isocyanates KW - Toluene 2,4-Diisocyanate KW - Hypersensitivity LA - eng PY - 2025 T2 - Current Opinion in Allergy and Clinical Immunology T2 - Current Opinion in Allergy and Clinical Immunology, 2025, v. 25, no. 2 TI - New Mechanisms in Diisocyanate-mediated Allergy/toxicity: Are MicroRNAs in Play? VL - 25 UR - https://stacks.cdc.gov/view/cdc/261954 ER -
Emergency Department Workers' Perceived Support and Emotional Impact After Workplace Violence.

Gillespie, Gordon Lee ;

Cooper, Sherry Steele

January 1, 2026 | Journal of Forensic Nursing, 2026, v. 21, no. 1

Workplace violence (WPV) is a common experience among healthcare workers in the United States. Although WPV may affect workers physically, WPV can also affect workers' mental health. Emergency department (ED) workers' perceptions of available and necessary WPV support have not been previously reported.A cross-sectional survey design was used to exa ...

10/10/2026

Supporting Files

Title : Emergency Department Workers' Perceived Support and Emotional Impact After Workplace Violence. Personal Author(s) : Gillespie, Gordon Lee;Cooper, Sherry Steele;Bresler, Scott A.;Tamsukhin, Sara; Published Date : January 1, 2026 Pages in Document : 12-18 (14 pdf pages) Source : Journal of Forensic Nursing, 2026, v. 21, no. 1 DOI : https://doi.org/10.1097/JFN.0000000000000510 Journal Title : Journal of Forensic Nursing
Gillespie, G. L., Cooper, S. S., Bresler, S. A., & Tamsukhin, S. (2026). Emergency Department Workers' Perceived Support and Emotional Impact After Workplace Violence. Journal of Forensic Nursing, 21(1). https://doi.org/10.1097/JFN.0000000000000510

Gillespie, Gordon Lee, Sherry Steele Cooper, Scott A. Bresler, and Sara Tamsukhin. "Emergency Department Workers' Perceived Support and Emotional Impact After Workplace Violence." Journal of Forensic Nursing 21, no. 1 (2026). https://doi.org/10.1097/JFN.0000000000000510.

Gillespie, Gordon Lee, et al. "Emergency Department Workers' Perceived Support and Emotional Impact After Workplace Violence." Journal of Forensic Nursing, vol. 21, no. 1, 2026. Stacks. https://doi.org/10.1097/JFN.0000000000000510.
Export RIS Citation Information. TY - Journal Article AU - Gillespie, Gordon Lee AU - Cooper, Sherry Steele AU - Bresler, Scott A. AU - Tamsukhin, Sara AB - Workplace violence (WPV) is a common experience among healthcare workers in the United States. Although WPV may affect workers physically, WPV can also affect workers' mental health. Emergency department (ED) workers' perceptions of available and necessary WPV support have not been previously reported. AB - A cross-sectional survey design was used to examine ED workers' perceived level of WPV support and emotional impact that WPV causes them. This study was conducted at six Midwestern U.S. EDs. Respondents confidentially completed an adapted version of the Survey of Violence Experienced by Staff. Data analysis included descriptive statistics, t test, and Kruskal-Wallis test. AB - Respondents ( N = 206) who experienced WPV served as the analytical sample. Respondents predominantly agreed or strongly agreed that support was available after WPV ( n = 129, 63.2%). The predominant source of support after WPV was another colleague from the department ( n = 127, 62.3%). Less than half of respondents ( n = 96, 47.1%) indicated they agreed/strongly agreed that managers were supportive after verbal abuse, but 63.6% ( n = 126) indicated that managers were supportive after physical assault. There was no statistical difference between the emotional impact of verbal abuse compared with threats/assaults. AB - Forensic nurses and emergency nurses with forensic nursing training are situated to combine their expertise in trauma-informed care, evidence collection, and expert testimony to support victimized ED workers. Timely support should be offered regardless of the category of WPV experienced. Insight into why support is perceived as available and accessible but may not be used warrants further study. AB - Author manuscript AN - cdc:261953 C4 - PMC12121692 DO - https://doi.org/10.1097/JFN.0000000000000510 IS - 1 J2 - Journal of Forensic Nursing KW - Attitude of Health Personnel KW - Emergency Nursing KW - Cross-Sectional Studies KW - Surveys and Questionnaires KW - Female KW - Male KW - Middle Aged KW - Humans KW - Workplace Violence KW - Emergency Service, Hospital KW - Adult KW - Social Support KW - workplace aggression KW - mental health KW - verbal abuse KW - assaults KW - forensic nursing KW - Humans KW - Cross-Sectional Studies KW - Workplace Violence KW - Emergency Service, Hospital KW - Female KW - Adult KW - Male KW - Surveys and Questionnaires KW - Social Support KW - Middle Aged KW - Emergency Nursing KW - Attitude of Health Personnel LA - eng PY - 2026 T2 - Journal of Forensic Nursing T2 - Journal of Forensic Nursing, 2026, v. 21, no. 1 TI - Emergency Department Workers' Perceived Support and Emotional Impact After Workplace Violence. VL - 21 UR - https://stacks.cdc.gov/view/cdc/261953 ER -
A Million Person Study Innovation: Evaluating Cognitive Impairment and Other Morbidity Outcomes From Chronic Radiation Exposure Through Linkages With the Centers For Medicaid and Medicare Services Assessment and Claims Data.

Dauer, Lawrence T. ;

Mumma, Michael T.

December 2024 | Radiation Research, 2024, v. 202, no. 6

The study of One Million U.S. Radiation Workers and Veterans, the Million Person Study (MPS), examines the health consequences, both cancer and non-cancer, of exposure to ionizing radiation received gradually over time. Recently the MPS has focused on mortality patterns from neurological and behavioral conditions, e.g., Parkinson's disease, Alzheim ...

10/10/2026

Supporting Files

Title : A Million Person Study Innovation: Evaluating Cognitive Impairment and Other Morbidity Outcomes From Chronic Radiation Exposure Through Linkages With the Centers For Medicaid and Medicare Services Assessment and Claims Data. Personal Author(s) : Dauer, Lawrence T.;Mumma, Michael T.;Lima, Julie C.;Cohen, Sarah S.;Andresen, Daniel;Bahadori, Amir A.;Bellamy, Michael;Bierman, David;Blattnig, Steve;French, Benjamin;Giunta, Eric;Held, Kathryn;Hertel, Nolan;Keohane, Laura;Leggett, Richard;Lipworth, Loren;Miller, Kathleen B.;Norman, Ryan;Samuels, Caleigh;Thomas, Kali S.;Tolmachev, Sergei;Walsh, Linda;Boice, John D.; Published Date : December 2024 Pages in Document : 847-861 (28 pdf pages) Source : Radiation Research, 2024, v. 202, no. 6 DOI : https://doi.org/10.1667/RADE-23-00186.1 Journal Title : Radiation Research
Dauer, L. T., Mumma, M. T., Lima, J. C., Cohen, S. S., Andresen, D., Bahadori, A. A., Bellamy, M., Bierman, D., Blattnig, S., French, B., Giunta, E., Held, K., Hertel, N., Keohane, L., Leggett, R., Lipworth, L., Miller, K. B., Norman, R., Samuels, C., ... Boice, J. D. (2024). A Million Person Study Innovation: Evaluating Cognitive Impairment and Other Morbidity Outcomes From Chronic Radiation Exposure Through Linkages With the Centers For Medicaid and Medicare Services Assessment and Claims Data. Radiation Research, 202(6). https://doi.org/10.1667/RADE-23-00186.1

Dauer, Lawrence T., Michael T. Mumma, Julie C. Lima, Sarah S. Cohen, Daniel Andresen, Amir A. Bahadori, and Michael Bellamy, et al.. "A Million Person Study Innovation: Evaluating Cognitive Impairment and Other Morbidity Outcomes From Chronic Radiation Exposure Through Linkages With the Centers For Medicaid and Medicare Services Assessment and Claims Data." Radiation Research 202, no. 6 (2024). https://doi.org/10.1667/RADE-23-00186.1.

Dauer, Lawrence T., et al. "A Million Person Study Innovation: Evaluating Cognitive Impairment and Other Morbidity Outcomes From Chronic Radiation Exposure Through Linkages With the Centers For Medicaid and Medicare Services Assessment and Claims Data." Radiation Research, vol. 202, no. 6, 2024. Stacks. https://doi.org/10.1667/RADE-23-00186.1.
Export RIS Citation Information. TY - Journal Article AU - Dauer, Lawrence T. AU - Mumma, Michael T. AU - Lima, Julie C. AU - Cohen, Sarah S. AU - Andresen, Daniel AU - Bahadori, Amir A. AU - Bellamy, Michael AU - Bierman, David AU - Blattnig, Steve AU - French, Benjamin AU - Giunta, Eric AU - Held, Kathryn AU - Hertel, Nolan AU - Keohane, Laura AU - Leggett, Richard AU - Lipworth, Loren AU - Miller, Kathleen B. AU - Norman, Ryan AU - Samuels, Caleigh AU - Thomas, Kali S. AU - Tolmachev, Sergei AU - Walsh, Linda AU - Boice, John D. AB - The study of One Million U.S. Radiation Workers and Veterans, the Million Person Study (MPS), examines the health consequences, both cancer and non-cancer, of exposure to ionizing radiation received gradually over time. Recently the MPS has focused on mortality patterns from neurological and behavioral conditions, e.g., Parkinson's disease, Alzheimer's disease, dementia, and motor neuron disease such as amyotrophic lateral sclerosis. A fuller picture of radiation-related late effects comes from studying both mortality and the occurrence (incidence) of conditions not leading to death. Accordingly, the MPS is identifying neurocognitive diagnoses from fee-for-service insurance claims from the Centers for Medicare and Medicaid Services (CMS), among Medicare beneficiaries beginning in 1999 (the earliest date claims data are available). Linkages to date have identified ∼540,000 workers with available health information. Such linkages provide individual information on important co-factor and confounding variables such as smoking, alcohol consumption, blood pressure, obesity, diabetes and many other health and demographic characteristics. The total person-level set of time-dependent variables, outcomes, organ-specific dose measures, co-factors, and demographics will be massive and much too large to be evaluated with standard software. Thus, development of specialized open-source software designed for large datasets (Colossus) is nearly complete. The wealth of information available from CMS claims data, coupled with individual dose reconstructions, will thus greatly enhance the quality and precision of health evaluations for this new field of low-dose radiation and neurocognitive effects. AB - Author manuscript AN - cdc:261952 C4 - PMC12001738 DO - https://doi.org/10.1667/RADE-23-00186.1 IS - 6 J2 - Radiation Research KW - Medicare KW - Female KW - Radiation Exposure KW - Cognition Disorders KW - Male KW - Humans KW - Centers for Medicare and Medicaid Services, U.S. KW - Humans KW - Radiation Exposure KW - Centers for Medicare and Medicaid Services, U.S. KW - Male KW - Medicare KW - Female KW - Cognition Disorders LA - eng PY - 2024 T2 - Radiation Research T2 - Radiation Research, 2024, v. 202, no. 6 TI - A Million Person Study Innovation: Evaluating Cognitive Impairment and Other Morbidity Outcomes From Chronic Radiation Exposure Through Linkages With the Centers For Medicaid and Medicare Services Assessment and Claims Data. VL - 202 UR - https://stacks.cdc.gov/view/cdc/261952 ER -
Transmission of a Human Isolate of Clade 2.3.4.4b A(H5N1) Virus in Ferrets.

Pulit-Penaloza, Joanna A. ;

Belser, Jessica A.

December 2024 | Nature, 2024, v. 636, no. 8043

Since 2020, there has been unprecedented global spread of highly pathogenic avian influenza A(H5N1) in wild bird populations with spillover into a variety of mammalian species and sporadically humans. In March 2024, clade 2.3.4.4b A(H5N1) virus was first detected in dairy cattle in the USA, with subsequent detection in numerous states, leading to m ...

10/10/2026

Supporting Files

Title : Transmission of a Human Isolate of Clade 2.3.4.4b A(H5N1) Virus in Ferrets. Personal Author(s) : Pulit-Penaloza, Joanna A.;Belser, Jessica A.;Brock, Nicole;Kieran, Troy J.;Sun, Xiangjie;Pappas, Claudia;Zeng, Hui;Carney, Paul;Chang, Jessie;Bradley-Ferrell, Brandon;Stevens, James;De La Cruz, Juan A.;Hatta, Yasuko;Di, Han;Davis, C. Todd;Tumpey, Terrence M.;Maines, Taronna R.; Published Date : December 2024 Pages in Document : 705-710 (23 pdf pages) Source : Nature, 2024, v. 636, no. 8043 DOI : https://doi.org/10.1038/s41586-024-08246-7 Journal Title : Nature
Pulit-Penaloza, J. A., Belser, J. A., Brock, N., Kieran, T. J., Sun, X., Pappas, C., Zeng, H., Carney, P., Chang, J., Bradley-Ferrell, B., Stevens, J., De La Cruz, J. A., Hatta, Y., Di, H., Davis, C. T., Tumpey, T. M., & Maines, T. R. (2024). Transmission of a Human Isolate of Clade 2.3.4.4b A(H5N1) Virus in Ferrets. Nature, 636(8043). https://doi.org/10.1038/s41586-024-08246-7

Pulit-Penaloza, Joanna A., Jessica A. Belser, Nicole Brock, Troy J. Kieran, Xiangjie Sun, Claudia Pappas, and Hui Zeng, et al.. "Transmission of a Human Isolate of Clade 2.3.4.4b A(H5N1) Virus in Ferrets." Nature 636, no. 8043 (2024). https://doi.org/10.1038/s41586-024-08246-7.

Pulit-Penaloza, Joanna A., et al. "Transmission of a Human Isolate of Clade 2.3.4.4b A(H5N1) Virus in Ferrets." Nature, vol. 636, no. 8043, 2024. Stacks. https://doi.org/10.1038/s41586-024-08246-7.
Export RIS Citation Information. TY - Journal Article AU - Pulit-Penaloza, Joanna A. AU - Belser, Jessica A. AU - Brock, Nicole AU - Kieran, Troy J. AU - Sun, Xiangjie AU - Pappas, Claudia AU - Zeng, Hui AU - Carney, Paul AU - Chang, Jessie AU - Bradley-Ferrell, Brandon AU - Stevens, James AU - De La Cruz, Juan A. AU - Hatta, Yasuko AU - Di, Han AU - Davis, C. Todd AU - Tumpey, Terrence M. AU - Maines, Taronna R. AB - Since 2020, there has been unprecedented global spread of highly pathogenic avian influenza A(H5N1) in wild bird populations with spillover into a variety of mammalian species and sporadically humans AB - . In March 2024, clade 2.3.4.4b A(H5N1) virus was first detected in dairy cattle in the USA, with subsequent detection in numerous states AB - , leading to more than a dozen confirmed human cases AB - . In this study, we used the ferret, a well-characterized animal model that permits concurrent investigation of viral pathogenicity and transmissibility AB - , in the evaluation of A/Texas/37/2024 (TX/37) A(H5N1) virus isolated from a dairy farm worker in Texas AB - . Here we show that the virus has a remarkable ability for robust systemic infection in ferrets, leading to high levels of virus shedding and spread to naive contacts. Ferrets inoculated with TX/37 rapidly exhibited a severe and fatal infection, characterized by viraemia and extrapulmonary spread. The virus efficiently transmitted in a direct contact setting and was capable of indirect transmission through fomites. Airborne transmission was corroborated by the detection of infectious virus shed into the air by infected animals, albeit at lower levels compared to those of the highly transmissible human seasonal and swine-origin H1 subtype strains. Our results show that despite maintaining an avian-like receptor-binding specificity, TX/37 exhibits heightened virulence, transmissibility and airborne shedding relative to other clade 2.3.4.4b virus isolated before the 2024 cattle outbreaks AB - , underscoring the need for continued public health vigilance. AB - Author manuscript AN - cdc:261951 C4 - PMC12004158 DO - https://doi.org/10.1038/s41586-024-08246-7 IS - 8043 J2 - Nature KW - Orthomyxoviridae Infections KW - Virulence KW - Animals KW - Ferrets KW - Hemagglutinin Glycoproteins, Influenza Virus KW - Polysaccharides KW - Respiratory Aerosols and Droplets KW - Virus Shedding KW - Male KW - Humans KW - Influenza A Virus, H5N1 Subtype KW - Disease Models, Animal KW - Influenza, Human KW - Receptors, Virus KW - Animals KW - Humans KW - Male KW - Disease Models, Animal KW - Ferrets KW - Influenza A Virus, H5N1 Subtype KW - Influenza, Human KW - Orthomyxoviridae Infections KW - Virus Shedding KW - Virulence KW - Hemagglutinin Glycoproteins, Influenza Virus KW - Respiratory Aerosols and Droplets KW - Receptors, Virus KW - Polysaccharides LA - eng PY - 2024 T2 - Nature T2 - Nature, 2024, v. 636, no. 8043 TI - Transmission of a Human Isolate of Clade 2.3.4.4b A(H5N1) Virus in Ferrets. VL - 636 UR - https://stacks.cdc.gov/view/cdc/261951 ER -
Local Supports to Break the Cycle: a Description of Intersectional Interventions to Address Adverse Childhood Experiences and Drug Overdose.

Myrick, Amie C. ;

Adams, Camille A.

June 9, 2025 | Journal of Public Health Management and Practice : JPHMP, 2025, v. 31, no. 2

Adverse childhood experiences (ACEs), substance use disorders (SUDs), and overdose are interconnected issues impacting individuals and communities at multiple levels of the social ecology and across generations. Few studies describe approaches that intentionally and simultaneously address these issues.This paper examines activities of 15 sites acro ...

10/10/2026

Supporting Files

Title : Local Supports to Break the Cycle: a Description of Intersectional Interventions to Address Adverse Childhood Experiences and Drug Overdose. Personal Author(s) : Myrick, Amie C.;Adams, Camille A.;Cremer, Laura J.;Filion, Nicole;Haddad, Stephanie;Snyder, Caroline;Wisdom, April; Published Date : June 9, 2025 Pages in Document : 227-233 (13 pdf pages) Source : Journal of Public Health Management and Practice : JPHMP, 2025, v. 31, no. 2 DOI : https://doi.org/10.1097/PHH.0000000000002042 Journal Title : Journal of Public Health Management and Practice : JPHMP
Myrick, A. C., Adams, C. A., Cremer, L. J., Filion, N., Haddad, S., Snyder, C., & Wisdom, A. (2025). Local Supports to Break the Cycle: a Description of Intersectional Interventions to Address Adverse Childhood Experiences and Drug Overdose. Journal of Public Health Management and Practice : JPHMP, 31(2). https://doi.org/10.1097/PHH.0000000000002042

Myrick, Amie C., Camille A. Adams, Laura J. Cremer, Nicole Filion, Stephanie Haddad, Caroline Snyder, and April Wisdom. "Local Supports to Break the Cycle: a Description of Intersectional Interventions to Address Adverse Childhood Experiences and Drug Overdose." Journal of Public Health Management and Practice : JPHMP 31, no. 2 (2025). https://doi.org/10.1097/PHH.0000000000002042.

Myrick, Amie C., et al. "Local Supports to Break the Cycle: a Description of Intersectional Interventions to Address Adverse Childhood Experiences and Drug Overdose." Journal of Public Health Management and Practice : JPHMP, vol. 31, no. 2, 2025. Stacks. https://doi.org/10.1097/PHH.0000000000002042.
Export RIS Citation Information. TY - Journal Article AU - Myrick, Amie C. AU - Adams, Camille A. AU - Cremer, Laura J. AU - Filion, Nicole AU - Haddad, Stephanie AU - Snyder, Caroline AU - Wisdom, April AB - Adverse childhood experiences (ACEs), substance use disorders (SUDs), and overdose are interconnected issues impacting individuals and communities at multiple levels of the social ecology and across generations. Few studies describe approaches that intentionally and simultaneously address these issues. AB - This paper examines activities of 15 sites across the country that were designed to simultaneously prevent ACEs, SUD, and overdose. This paper describes the work at the intersection as well as gaps and opportunities. Describing ways to implement intersectional programming may assist other organizations in taking similar steps in their communities. AB - From December 2020 through July 15, 2023, funded sites received technical assistance from the National Association of County and City Health Officials and the Centers for Disease Control and Prevention for 18 months to support the implementation, adaptation, and/or expansion of evidence-based programs to address ACEs, SUD, and overdose. AB - Activities were coded to identify intersectional interventions that addressed ACEs, SUD, and overdose. Most of the ACEs prevention strategies and overdose prevention priority areas/guiding principles from which communities could choose were represented. Most activities were implemented with caregivers and families and addressed ACEs through interventions to lessen harm or to promote social norms. Primary prevention and coordination of resources were the most used overdose prevention priority area/guiding principle. AB - It is possible to address the intersection of ACEs, SUD, and overdose on a local level. Opportunities to further address the intersection include incorporating more secondary and tertiary prevention strategies, expanding economic supports, and increasing the work focused on equity. AB - Author manuscript AN - cdc:261950 C4 - PMC12146908 DO - https://doi.org/10.1097/PHH.0000000000002042 IS - 2 J2 - Journal of Public Health Management and Practice : JPHMP KW - Child KW - Adverse Childhood Experiences KW - Humans KW - Substance-Related Disorders KW - Drug Overdose KW - adverse childhood experiences KW - intersection KW - overdose KW - prevention KW - substance use disorders KW - Humans KW - Drug Overdose KW - Adverse Childhood Experiences KW - Substance-Related Disorders KW - Child LA - eng PY - 2025 T2 - Journal of Public Health Management and Practice : JPHMP T2 - Journal of Public Health Management and Practice : JPHMP, 2025, v. 31, no. 2 TI - Local Supports to Break the Cycle: a Description of Intersectional Interventions to Address Adverse Childhood Experiences and Drug Overdose. VL - 31 UR - https://stacks.cdc.gov/view/cdc/261950 ER -
Evaluation of Test-negative Design Estimates of Influenza Vaccine Effectiveness in the Context of Multiple, Co-circulating, Vaccine Preventable Respiratory Viruses.

Leis, Aleda M. ;

Wagner, Abram

December 2024 | Vaccine, 2024, v. 42, no. 26

Test-negative design (TND) studies are cornerstones of vaccine effectiveness (VE) monitoring for influenza. The introduction of SARS-CoV-2 and RSV vaccines complicate the analysis of this design, with control selection restriction based on other pathogen diagnosis proposed as a solution. We conducted a simulation study and secondary analysis of 201 ...

10/10/2026

Supporting Files

Title : Evaluation of Test-negative Design Estimates of Influenza Vaccine Effectiveness in the Context of Multiple, Co-circulating, Vaccine Preventable Respiratory Viruses. Personal Author(s) : Leis, Aleda M.;Wagner, Abram;Flannery, Brendan;Chung, Jessie R.;Monto, Arnold S.;Martin, Emily T.; Published Date : December 2024 Pages in Document : 126493 (10 pdf pages) Source : Vaccine, 2024, v. 42, no. 26 DOI : https://doi.org/10.1016/j.vaccine.2024.126493 Journal Title : Vaccine
Leis, A. M., Wagner, A., Flannery, B., Chung, J. R., Monto, A. S., & Martin, E. T. (2024). Evaluation of Test-negative Design Estimates of Influenza Vaccine Effectiveness in the Context of Multiple, Co-circulating, Vaccine Preventable Respiratory Viruses. Vaccine, 42(26). https://doi.org/10.1016/j.vaccine.2024.126493

Leis, Aleda M., Abram Wagner, Brendan Flannery, Jessie R. Chung, Arnold S. Monto, and Emily T. Martin. "Evaluation of Test-negative Design Estimates of Influenza Vaccine Effectiveness in the Context of Multiple, Co-circulating, Vaccine Preventable Respiratory Viruses." Vaccine 42, no. 26 (2024). https://doi.org/10.1016/j.vaccine.2024.126493.

Leis, Aleda M., et al. "Evaluation of Test-negative Design Estimates of Influenza Vaccine Effectiveness in the Context of Multiple, Co-circulating, Vaccine Preventable Respiratory Viruses." Vaccine, vol. 42, no. 26, 2024. Stacks. https://doi.org/10.1016/j.vaccine.2024.126493.
Export RIS Citation Information. TY - Journal Article AU - Leis, Aleda M. AU - Wagner, Abram AU - Flannery, Brendan AU - Chung, Jessie R. AU - Monto, Arnold S. AU - Martin, Emily T. AB - Test-negative design (TND) studies are cornerstones of vaccine effectiveness (VE) monitoring for influenza. The introduction of SARS-CoV-2 and RSV vaccines complicate the analysis of this design, with control selection restriction based on other pathogen diagnosis proposed as a solution. We conducted a simulation study and secondary analysis of 2017-18 and 2018-19 TND estimates from a Southeast Michigan ambulatory population to evaluate RSV-status-based control restriction. Simulations suggest that with vaccine-preventable RSV, influenza VE could be moderately biased with RSV prevalence ≥25 % of controls. Real-world analysis showed 151 influenza-negative adults (10.4 %) had RSV detected from the enrollment nasal swab. There were minimal differences in results of adjusted models with or without RSV exclusion from control groups. Findings suggest that inclusion of RSV cases in the control group of TND studies for influenza VE, particularly where RSV is not vaccine preventable, does not currently pose a major concern for bias in VE estimates. AB - Author manuscript AN - cdc:261949 C4 - PMC12291198 DO - https://doi.org/10.1016/j.vaccine.2024.126493 IS - 26 J2 - Vaccine KW - Adolescent KW - Female KW - SARS-CoV-2 KW - Respiratory Syncytial Virus Infections KW - Aged KW - COVID-19 KW - Young Adult KW - Respiratory Syncytial Virus Vaccines KW - Influenza Vaccines KW - Vaccine Efficacy KW - Male KW - Humans KW - Middle Aged KW - Adult KW - Influenza, Human KW - Test-negative design KW - Bias KW - Vaccine efficacy KW - Humans KW - Influenza Vaccines KW - Influenza, Human KW - Respiratory Syncytial Virus Infections KW - Adult KW - Middle Aged KW - Female KW - Vaccine Efficacy KW - Male KW - COVID-19 KW - Aged KW - SARS-CoV-2 KW - Young Adult KW - Respiratory Syncytial Virus Vaccines KW - Adolescent LA - eng PY - 2024 T2 - Vaccine T2 - Vaccine, 2024, v. 42, no. 26 TI - Evaluation of Test-negative Design Estimates of Influenza Vaccine Effectiveness in the Context of Multiple, Co-circulating, Vaccine Preventable Respiratory Viruses. VL - 42 UR - https://stacks.cdc.gov/view/cdc/261949 ER -
System-level Interventions For Fall Risk Assessment, Fall Prevention and Fall Injury Prevention in Long-term Care Facilities: a Scoping Review.

Wi, Dahee ;

Ustach, Andrew

November 2025 | Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, 2025, v. 31, no. 6

Older adults living in long-term care facilities (LTCFs) are at high risk for falls. Interventions to prevent falls and fall-related injury in this population may be individual-level or system-focused interventions. However, relatively little attention has been given to research on system-focused interventions. This scoping review seeks to synthesi ...

10/10/2026

Supporting Files

Title : System-level Interventions For Fall Risk Assessment, Fall Prevention and Fall Injury Prevention in Long-term Care Facilities: a Scoping Review. Personal Author(s) : Wi, Dahee;Ustach, Andrew;Jung, Wonkyung;Lim, Sungwon;Thompson, Hilaire; Published Date : November 2025 Pages in Document : 448-456 (20 pdf pages) Source : Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, 2025, v. 31, no. 6 DOI : https://doi.org/10.1136/ip-2024-045386 Journal Title : Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
Wi, D., Ustach, A., Jung, W., Lim, S., & Thompson, H. (2025). System-level Interventions For Fall Risk Assessment, Fall Prevention and Fall Injury Prevention in Long-term Care Facilities: a Scoping Review. Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, 31(6). https://doi.org/10.1136/ip-2024-045386

Wi, Dahee, Andrew Ustach, Wonkyung Jung, Sungwon Lim, and Hilaire Thompson. "System-level Interventions For Fall Risk Assessment, Fall Prevention and Fall Injury Prevention in Long-term Care Facilities: a Scoping Review." Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention 31, no. 6 (2025). https://doi.org/10.1136/ip-2024-045386.

Wi, Dahee, et al. "System-level Interventions For Fall Risk Assessment, Fall Prevention and Fall Injury Prevention in Long-term Care Facilities: a Scoping Review." Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, vol. 31, no. 6, 2025. Stacks. https://doi.org/10.1136/ip-2024-045386.
Export RIS Citation Information. TY - Journal Article AU - Wi, Dahee AU - Ustach, Andrew AU - Jung, Wonkyung AU - Lim, Sungwon AU - Thompson, Hilaire AB - Older adults living in long-term care facilities (LTCFs) are at high risk for falls. Interventions to prevent falls and fall-related injury in this population may be individual-level or system-focused interventions. However, relatively little attention has been given to research on system-focused interventions. This scoping review seeks to synthesise previous studies on the effects of system-focused interventions for fall prevention in LTCFs. AB - We searched Ovid-Medline, CINAHL and Embase databases from 2007 to 2024 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for Scoping Reviews. We conducted a narrative synthesis to summarise findings from the included studies. AB - In the initial search, 403 studies were identified and underwent title and abstract screening resulting in 116 articles retrieved for full-text review. 20 studies were included in the final data extraction. System-level fall prevention interventions evaluated in LTCFs include (1) multicomponent and multidisciplinary programmes, (2) environmental adaptations, (3) technological adaptations, and (4) staff education and training programmes. 11 out of 17 included quantitative studies reported significant effects of system-focused interventions to reduce falls in LTCFs. AB - This scoping review reveals the effectiveness of system-level fall prevention strategies in LTCFs. Enhancing training, customising tools and fostering a supportive leadership culture are vital for improving fall prevention practices in LTCFs. AB - Author manuscript AN - cdc:261948 C4 - PMC12041291 DO - https://doi.org/10.1136/ip-2024-045386 IS - 6 J2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention KW - Nursing Homes KW - Risk Assessment KW - Wounds and Injuries KW - Aged KW - Accidental Falls KW - Humans KW - Homes for the Aged KW - Long-Term Care KW - Fall KW - Interventions KW - Older People KW - Residential Institution KW - Humans KW - Accidental Falls KW - Long-Term Care KW - Risk Assessment KW - Aged KW - Wounds and Injuries KW - Nursing Homes KW - Homes for the Aged LA - eng PY - 2025 T2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention T2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, 2025, v. 31, no. 6 TI - System-level Interventions For Fall Risk Assessment, Fall Prevention and Fall Injury Prevention in Long-term Care Facilities: a Scoping Review. VL - 31 UR - https://stacks.cdc.gov/view/cdc/261948 ER -
Characteristics of Survivors Enrolled in the World Trade Center Health Program.

Liu, Ruiling ;

Santiago-Colón, Albeliz

February 6, 2025 | Archives of Environmental & Occupational Health, 2025, v. 79, no. 56

The World Trade Center (WTC) Health Program is a limited federal health care program that provides medical monitoring and treatment for WTC-related health conditions to responders and survivors impacted by the terrorist attacks on September 11, 2001.This study described the characteristics of the Program survivor members (who lived, worked, went to ...

10/10/2026

Supporting Files

Title : Characteristics of Survivors Enrolled in the World Trade Center Health Program. Personal Author(s) : Liu, Ruiling;Santiago-Colón, Albeliz;Butturini, Emma;Kubale, Travis L.;Reibman, Joan; Published Date : February 6, 2025 Pages in Document : 185-198 (21 pdf pages) Source : Archives of Environmental & Occupational Health, 2025, v. 79, no. 56 DOI : https://doi.org/10.1080/19338244.2024.2410495 Journal Title : Archives of Environmental & Occupational Health
Liu, R., Santiago-Colón, A., Butturini, E., Kubale, T. L., & Reibman, J. (2025). Characteristics of Survivors Enrolled in the World Trade Center Health Program. Archives of Environmental & Occupational Health, 79(56). https://doi.org/10.1080/19338244.2024.2410495

Liu, Ruiling, Albeliz Santiago-Colón, Emma Butturini, Travis L. Kubale, and Joan Reibman. "Characteristics of Survivors Enrolled in the World Trade Center Health Program." Archives of Environmental & Occupational Health 79, no. 56 (2025). https://doi.org/10.1080/19338244.2024.2410495.

Liu, Ruiling, et al. "Characteristics of Survivors Enrolled in the World Trade Center Health Program." Archives of Environmental & Occupational Health, vol. 79, no. 56, 2025. Stacks. https://doi.org/10.1080/19338244.2024.2410495.
Export RIS Citation Information. TY - Journal Article AU - Liu, Ruiling AU - Santiago-Colón, Albeliz AU - Butturini, Emma AU - Kubale, Travis L. AU - Reibman, Joan AB - The World Trade Center (WTC) Health Program is a limited federal health care program that provides medical monitoring and treatment for WTC-related health conditions to responders and survivors impacted by the terrorist attacks on September 11, 2001.This study described the characteristics of the Program survivor members (who lived, worked, went to school, daycare or adult daycare or present in the New York City Disaster Area of 9/11/2001) to stimulate innovative ideas for improving healthcare services, generate new research interest, and serve as a reference for future research on this population. Administrative and medical claims data collected from the Program start date (07/01/2011) through 2022 were used. As of 12/31/2022, there were 37,384 enrolled survivors: 5.0% were aged ≤21 years on 9/11/2001, 45.9% females, and 31.2% non-Hispanic Whites. A total of 24,148 (64.6%) were certified for at least one WTC-related condition, including neoplasms (36.0%), aerodigestive disorders (35.6%) and mental health conditions (18.6%); 22.9% were certified for more than one category. Certification rates of some WTC-related conditions differed by sex, age and race/ethnicity. WTC survivor population is diverse in sex, age and race/ethnicity, with a high proportion certified for certain WTC-related health conditions, providing great opportunities for research in various areas. AB - Author manuscript AN - cdc:261947 C4 - PMC11801494 DO - https://doi.org/10.1080/19338244.2024.2410495 IS - 56 J2 - Archives of Environmental & Occupational Health KW - Adolescent KW - Female KW - Aged KW - Young Adult KW - Mental Disorders KW - Child KW - Survivors KW - Neoplasms KW - Infant KW - Male KW - Middle Aged KW - Humans KW - September 11 Terrorist Attacks KW - Child, Preschool KW - Adult KW - World Trade Center Health Program KW - WTC-related health conditions KW - WTC survivors KW - WTC youth KW - Humans KW - September 11 Terrorist Attacks KW - Male KW - Female KW - Survivors KW - Adult KW - Middle Aged KW - Young Adult KW - Adolescent KW - Aged KW - Child KW - Child, Preschool KW - Neoplasms KW - Infant KW - Mental Disorders LA - eng PY - 2025 T2 - Archives of Environmental & Occupational Health T2 - Archives of Environmental & Occupational Health, 2025, v. 79, no. 56 TI - Characteristics of Survivors Enrolled in the World Trade Center Health Program. VL - 79 UR - https://stacks.cdc.gov/view/cdc/261947 ER -

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