Details:

Alternative Title:
Lab Chip
Personal Author:
Klunder, Kevin J. ; Clark, Kaylee ; McCord, Cynthia ; Berg, Kathleen E. ; Minteer, Shelley D. ; ... More +
Klunder, Kevin J. ; Clark, Kaylee ; McCord, Cynthia ; Berg, Kathleen E. ; Minteer, Shelley D. ; Henry, Charles S. Less -
Description:
Combining electrochemistry with microfluidics is attractive for a wide array of applications including multiplexing, automation, and high-throughput screening. Electrochemical instrumentation also has the advantage of being low-cost and can enable high analyte sensitivity. For many electrochemical microfluidic applications, carbon electrodes are more desirable than noble metals because they are resistant to fouling, have high activity, and large electrochemical solvent windows. At present, fabrication of electrochemical microfluidic devices bearing integrated carbon electrodes remains a challenge. Here, a new system for integrating polycaprolactone (PCL) and carbon composite electrodes into microfluidics is presented. The PCL : carbon composites have excellent electrochemical activity towards a wide range of analytes as well as high electrical conductivity (∼1000 S m|). The new system utilizes a laser cutter for fast, simple fabrication of microfluidics using PCL as a bonding layer. As a proof-of-concept application, oil-in-water and water-in-oil droplets are electrochemically analysed. Small-scale electrochemical organic synthesis for TEMPO mediated alcohol oxidation is also demonstrated.
Subject:
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Carbon
Electric Capacitance
Electric Conductivity
Electrochemistry
Electrodes
Lab-On-A-Chip Devices
Polyesters

Source:
Lab Chip. 19(15):2589-2597
Pubmed ID:
31250868
Pubmed Central ID:
PMC6801002
Document Type:
Journal Article
Funding:
R01 OH010662/OH/NIOSH CDC HHS/United States ; R01OH010662/ACL/ACL HHS/United States ; R21 ES024719/ES/NIEHS NIH HHS/United States ; R33 ES024719/ES/NIEHS NIH HHS/United States
R01 OH010662/OH/NIOSH CDC HHS/United States ; R01OH010662/ACL/ACL HHS/United States ; R21 ES024719/ES/NIEHS NIH HHS/United States ; R33 ES024719/ES/NIEHS NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:84d889a97fdfe5681e5f8f1e4ff3556cdb2e4a90bdf4338c5fe5d7ad70726a73
File Type:

Supporting Files

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