Racial/ethnic disparities in prostate cancer incidence, distant stage diagnosis, and mortality by U.S. census region and age-group, 2012–2015.

Details

• Alternative Title:
  Cancer Epidemiol Biomarkers Prev
• Personal Author:
  Iyengar, Siddharth ; Hall, Ingrid J. ; Sabatino, Susan A.
• Description:
  Background:
  
  We sought to characterize recent prostate cancer incidence, distant stage diagnosis, and mortality rates by region, race/ethnicity, and age-group.
  
  Methods:
  
  In SEER*Stat, we examined age-specific and age-adjusted prostate cancer incidence, distant stage diagnosis, and mortality rates by race/ethnicity, Census region, and age group. Incidence and mortality analyses included men diagnosed with (n=723,269) and dying of (n=112,116) prostate cancer between 2012–2015.
  
  Results:
  
  Non-Hispanic black (NHB) and NH Asian/Pacific Islander (NHAPI) men had the highest and lowest rates, respectively, for each indicator across regions and age-groups. Hispanic men had lower incidence and mortality rates than non-Hispanic white (NHW) men in all regions except the Northeast where they had higher incidence (RR 1.16 (95%CI 1.14–1.19)) and similar mortality. Hispanics had higher distant stage rates in the Northeast (RR 1.18 (95%CI 1.08–1.28)) and South (RR 1.22 (95%CI 1.15–1.30)), but similar rates in other regions. Non-Hispanic American Indian/Alaskan Native (NHAIAN) men had higher distant stage rates than NHWs in the West (RR 1.38 (95%CI 1.15–1.65)). NHBs and Hispanics had higher distant stage rates than NHWs among those ages 55–69 years (RR 2.91 (95% CI 2.81–3.02) and 1.24 (95% CI 1.18–1.31) respectively), despite lower overall incidence for Hispanics in this age group.
  
  Conclusions:
  
  For Hispanic and NHAIAN men, prostate cancer indicators varied by region, while NHB and NHAPI men consistently had the highest and lowest rates, respectively, across regions.
  
  Impact:
  
  Regional and age-group differences in prostate cancer indicators between populations may improve understanding of prostate cancer risk and help inform screening decisions.
  
  
• Subjects:
  Aged Censuses Healthcare Disparities History, 21st Century Humans Incidence Male Middle Aged Mortality Prostatic Neoplasms
• Source:
  Cancer Epidemiol Biomarkers Prev. 29(7):1357-1364
• Pubmed ID:
  32303533
• Pubmed Central ID:
  PMC7334051
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHS/United States
• Genre:
  Historical Article
• Place as Subject:
  United States
• Volume:
  29
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:349aa4353d319f6190f665d631dc30003ebf5713bfbf121b67091e798fa46655
• Download URL:
  https://stacks.cdc.gov/view/cdc/90274/cdc_90274_DS1.pdf
• File Type:
  [PDF - 575.18 KB ]