Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Okba, Nisreen M.A. ; Widjaja, Ivy ; Li, Wentao ; GeurtsvanKessel, Corine H. ; Farag, Elmoubasher A.B.A. ; ... More +
Okba, Nisreen M.A. ; Widjaja, Ivy ; Li, Wentao ; GeurtsvanKessel, Corine H. ; Farag, Elmoubasher A.B.A. ; Al-Hajri, Mohammed ; Park, Wan Beom ; Oh, Myoung-don ; Reusken, Chantal B.E.M. ; Koopmans, Marion P.G. ; Bosch, Berend-Jan ; Haagmans, Bart L. ; Less -
Description:
We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assays correlated strongly with virus-neutralizing antibody titers, proving their use for serologic confirmatory diagnosis of Middle East respiratory syndrome.
Subject:
[+]
Antibodies, Viral / Blood
Coronavirus Infections
Coronavirus Infections / Blood
Enzyme-Linked Immunosorbent Assay
Humans
Immunoassay
Middle East Respiratory Syndrome Coronavirus
Serologic Tests
Species Specificity

Source:
Emerg Infect Dis. 26(5):1024-1027 ;
Pubmed ID:
32150528
Pubmed Central ID:
PMC7181916
Document Type:
Letter ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:f7c1a1eae4894f6ad8ca1f8156d96183f725936e853ddbece8e54b3f216471a0
File Type:

Supporting Files

• 	19-0921-F.gif	gif
  	19-0921-F.jpg	jpeg
  	19-0921-Techapp-s1.pdf	pdf
  	19-0921.nxml	xml

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