Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Guan, Qingtian ; Almutairi, Talal S. ; Alhalouli, Tahani ; Pain, Arnab ; Alasmari, Faisal
• Description:
  Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.
• Subjects:
  3K1 Antimicrobial Resistance Bacteria Biopsy Drug Resistance Imported Infectious Diseases Indels Leprosy Metagenomics Metagenomics Of Imported Multidrug-Resistant Mycobacterium Leprae, Saudi Arabia, 2017 Mycobacterium Leprae Research Letter RpoB Rrs Single-nucleotide Polymorphisms Tuberculosis And Other Mycobacteria

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• Source:
  Emerg Infect Dis. 26(3):615-617
• Pubmed ID:
  32091380
• Pubmed Central ID:
  PMC7045828
• Document Type:
  Journal Article
• Place as Subject:
  Philippines ; Saudi Arabia
• Location:
  Asia ; Middle East
• Volume:
  26
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:cd6c64e999439bfebfc5670a759f0793549b3e383f97203e581ee771a9d586fc
• Download URL:
  https://stacks.cdc.gov/view/cdc/85671/cdc_85671_DS1.pdf
• File Type:
  [PDF - 261.27 KB ]