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Effectiveness of Immune Checkpoint Inhibitors in Transplant Recipients with Progressive Multifocal Leukoencephalopathy
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November 2019
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Source: Emerg Infect Dis. 25(11):2145-2147
Details:
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Alternative Title:Emerg Infect Dis
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Personal Author:
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Description:Antibodies against PD1 have been used to treat progressive multifocal leukoencephalopathy (PML), a rare brain disease caused by JC virus. We used these antibodies (nivolumab) to treat PML in 3 kidney transplant recipients. All died within 8 weeks of diagnosis. Hence, nivolumab did not improve PML outcome after solid organ transplantation.
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Pubmed ID:31625858
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Pubmed Central ID:PMC6810212
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Volume:25
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Issue:11
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