Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines

Stein, Derek R.; Sroga, Patrycja; Warner, Bryce M.; Deschambault, Yvon; Poliquin, Guillaume; Safronetz, David

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Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines

Supporting Files Public Domain

August 17 2019
By Stein, Derek R. ; Sroga, Patrycja ; Warner, Bryce M. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Stein, Derek R. ; Sroga, Patrycja ; Warner, Bryce M. ; Deschambault, Yvon ; Poliquin, Guillaume ; Safronetz, David
Description:

Use of the vesicular stomatitis virus (VSV)-based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines' stability should the cold chain fail. We demonstrated that current cold chain conditions might tolerate significant variances without affecting efficacy.
Subjects:

Dispatch Ebola Virus Lassa Virus Temperature Stability Vaccines Vaccine Stability Vesicular Stomatitis Virus Viral Hemorrhagic Fever Viruses
Source:

Emerg Infect Dis. 25(8):1563-1566
Pubmed ID:

31141474
Pubmed Central ID:

PMC6649338
Document Type:

Journal Article
Place as Subject:

Canada
Location:

North America
Volume:

25
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:21b3c99ed0b0ca2ff8e407244a310d3276914d73a54ef994f7eb2e670e9d6e5a
Download URL:

https://stacks.cdc.gov/view/cdc/80340/cdc_80340_DS1.pdf
File Type:

[PDF - 1.68 MB ]

File Language:

English

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