Novel Picornavirus in Lambs with Severe Encephalomyelitis

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Forth, Leonie F. ; Scholes, Sandra F.E. ; Pesavento, Patricia A. ; Jackson, Kenneth ; Mackintosh, Adrienne ; Carson, Amanda ; Howie, Fiona ; Schlottau, Kore ; Wernike, Kerstin ; Pohlmann, Anne ; Höper, Dirk ; Beer, Martin
• Description:
  Using metagenomic analysis, we identified a novel picornavirus in young preweaned lambs with neurologic signs associated with severe nonsuppurative encephalitis and sensory ganglionitis in 2016 and 2017 in the United Kingdom. In situ hybridization demonstrated intralesional neuronotropism of this virus, which was also detected in archived samples of similarly affected lambs (1998-2014).
• Subjects:
  Disease Dispatch Encephalitis Encephalomyelitis Lambs Neurologic Novel Novel Picornavirus In Lambs With Severe Encephalomyelitis Ovine Picornavirus Sheep Viruses

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• Source:
  Emerg Infect Dis. 25(5):963-967
• Pubmed ID:
  31002069
• Pubmed Central ID:
  PMC6478204
• Document Type:
  Journal Article
• Place as Subject:
  United Kingdom ; England ; Scotland ; Wales
• Location:
  Europe
• Volume:
  25
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:78c2d0b5c9e396cde64b453c71568b1ca0c0c125ce63a87a04e4b4ab2662975f
• Download URL:
  https://stacks.cdc.gov/view/cdc/79353/cdc_79353_DS1.pdf
• File Type:
  [PDF - 2.27 MB ]