Case Series of Jamestown Canyon Virus Infections with Neurologic Outcomes, Canada, 2011–2016

Meier-Stephenson, Vanessa; Drebot, Michael A.; Dimitrova, Kristina; DiQuinzio, Melanie; Fonseca, Kevin; Forrest, David; Hatchette, Todd; Morshed, Muhammad; Patriquin, Glen; Poliquin, Guillaume; Saxinger, Lynora; Serhir, Bouchra; Tellier, Raymond; Therrien, Christian; Vrbova, Linda; Wood, Heidi

doi:10.3201/eid3005.221258

i

Case Series of Jamestown Canyon Virus Infections with Neurologic Outcomes, Canada, 2011–2016

Supporting Files Public Domain

5 2024
By Meier-Stephenson, Vanessa ; Drebot, Michael A. ; Dimitrova, Kristina ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Meier-Stephenson, Vanessa ; Drebot, Michael A. ; Dimitrova, Kristina ; DiQuinzio, Melanie ; Fonseca, Kevin ; Forrest, David ; Hatchette, Todd ; Morshed, Muhammad ; Patriquin, Glen ; Poliquin, Guillaume ; Saxinger, Lynora ; Serhir, Bouchra ; Tellier, Raymond ; Therrien, Christian ; Vrbova, Linda ; Wood, Heidi
Description:

Jamestown Canyon virus (JCV) is a mosquitoborne orthobunyavirus in the California serogroup that circulates throughout Canada and the United States. Most JCV exposures result in asymptomatic infection or a mild febrile illness, but JCV can also cause neurologic diseases, such as meningitis and encephalitis. We describe a case series of confirmed JCV-mediated neuroinvasive disease among persons from the provinces of British Columbia, Alberta, Quebec, and Nova Scotia, Canada, during 2011-2016. We highlight the case definitions, epidemiology, unique features and clinical manifestations, disease seasonality, and outcomes for those cases. Two of the patients (from Quebec and Nova Scotia) might have acquired JCV infections during travel to the northeastern region of the United States. This case series collectively demonstrates JCV's wide distribution and indicates the need for increased awareness of JCV as the underlying cause of meningitis/meningoencephalitis during mosquito season.
Subjects:

Adult Aged Aged, 80 And Over Encephalitis, California Encephalitis Virus, California Female History, 21st Century Humans Male Middle Aged
Keywords:

Arboviral Encephalitis Arboviruses California Serogroup Viruses Canada Jamestown Canyon Virus JCV Meningitis/Encephalitis Mosquito-borne Viruses Vector-borne Infections Viruses Zoonoses
Source:

Emerg Infect Dis. 2024; 30(5):874-881
Pubmed ID:

38666581
Pubmed Central ID:

PMC11060468
Document Type:

Journal Article
Place as Subject:

Canada
Volume:

30
Issue:

5
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:231ebe16a6e5182f4081916823566ddfcbe6dbb26e9e5277278246a9900b3823
Download URL:

https://stacks.cdc.gov/view/cdc/154849/cdc_154849_DS1.pdf
File Type:

[PDF - 713.18 KB ]

File Language:

English

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