Variant Creutzfeldt-Jakob Disease Death, United States

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Belay, Ermias D. ; Sejvar, James J. ; Shieh, Wun-Ju ; Wiersma, Steven T. ; Zou, Wen-Quan ; Gambetti, Pierluigi ; Hunter, Stephen ; Maddox, Ryan A. ; Crockett, Landis ; Zaki, Sherif R. ; Schonberger, Lawrence B.
• Description:
  The only variant Creutzfeldt-Jakob disease (vCJD) patient identified in the United States died in 2004, and the diagnosis was confirmed by analysis of autopsy tissue. The patient likely acquired the disease while growing up in Great Britain before immigrating to the United States in 1992. Additional vCJD patients continue to be identified outside the United Kingdom, including 2 more patients in Ireland, and 1 patient each in Japan, Portugal, Saudi Arabia, Spain, and the Netherlands. The reports of bloodborne transmission of vCJD in 2 patients, 1 of whom was heterozygous for methionine and valine at polymorphic codon 129, add to the uncertainty about the future of the vCJD outbreak.
• Subjects:
  Adult Creutzfeldt-Jakob Syndrome Fatal Outcome Female Humans Research
• Source:
  Emerg Infect Dis. 11(9):1351-1354.
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  11
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:aefc44701c90c00bb1abf0583c4980d8d4051c2c4548045cdd6d189290e2a653
• Download URL:
  https://stacks.cdc.gov/view/cdc/7877/cdc_7877_DS1.pdf
• File Type:
  [PDF - 179.39 KB ]