Influenza A (H3N2) Outbreak, Nepal

Daum, Luke T.; Shaw, Michael W.; Klimov, Alexander I.; Canas, Linda C.; Macias, Elizabeth A.; Niemeyer, Debra; Chambers, James P.; Renthal, Robert; Shrestha, Sanjaya K.; Acharya, Ramesh P.; Huzdar, Shankar P.; Rimal, Nirmal; Myint, Khin S.; Gould, Philip

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Influenza A (H3N2) Outbreak, Nepal

Published Date:

Aug 2005

Source:

Emerg Infect Dis. 11(8):1186-1191.

[PDF - 331.77 KB]

Details:

Personal Authors:

Daum, Luke T. ; Shaw, Michael W. ; Klimov, Alexander I. ; Canas, Linda C. ; Macias, Elizabeth A. ; ... More ▼

Keywords:

[+]

Description:

In July 2004, an outbreak of influenza A (H3N2) was detected at 3 Bhutanese refugee camps in southeastern Nepal. Hemagglutination inhibition showed that approximately 40% of the viruses from this outbreak were antigenically distinct from the A/Wyoming/3/03 vaccine strain. Four amino acid differences were observed in most of the 26 isolates compared with the A/Wyoming/3/2003 vaccine strain. All 4 substitutions are located within or adjacent to known antibody-binding sites. Several isolates showed a lysine-to-asparagine substitution at position 145 (K145N) in the hemagglutinin molecule, which may be noteworthy since position 145 is located within a glycosylation site and adjacent to an antibody-binding site. H3N2 viruses continue to drift from the vaccine strain and may remain as the dominant strains during the 2005-2006 influenza season. Thus, the 2005-2006 Northern Hemisphere vaccine strain was changed to A/California/7/2004, a virus with all 4 amino acid substitutions observed in these Nepalese isolates.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

05-0302-F1.gif	image/gif
05-0302-F1.jpg	image/jpeg
05-0302-F2.gif	image/gif
05-0302-F2.jpg	image/jpeg
05-0302-F3.gif	image/gif
05-0302-F3.jpg	image/jpeg
05-0302.nxml	text/plain
license.txt	text/plain

No Related Documents.

You May Also Like:

Outbreak of H3N2 Influenza at a US Military Base in Djibouti during the H1N1 Pandemic of 2009

Personal Author:

Cosby, Michael T.; Pimentel, Guillermo; Nevin, Remington L.; Fouad Ahmed, Salwa; Klena, John D.; Amir, Ehab; Younan, Mary; Browning, Robert; Sebeny, Peter J.;

Published:

Dec 05 2013

Source:

PLoS One. 2013; 8(12).

Description:

Background : Influenza pandemics have significant operational impact on deployed military personnel working in areas throughout the world. The US Department of Defense global influenza-like illness (ILI) surveillance network serves an important role ...

File Type:

[PDF - 835.57 KB]
Outbreak of Influenza A (H3N2) Variant Virus Infection among Attendees of an Agricultural Fair, Pennsylvania, USA, 2011

Personal Author:

Wong, Karen K.; Greenbaum, Adena; Moll, Maria E.; Lando, James; Moore, Erin L.; Ganatra, Rahul; Biggerstaff, Matthew; Lam, Eugene; Smith, Erica E.; Storms, Aaron D.; Miller, Jeffrey R.; Dato, Virginia; Nalluswami, Kumar; Nambiar, Atmaram; Silvestri, Sharon A.; Lute, James R.; Ostroff, Stephen; Hancock, Kathy; Branch, Alicia; Trock, Susan C.; Klimov, Alexander; Shu, Bo; Brammer, Lynnette; Epperson, Scott; Finelli, Lyn; Jhung, Michael A.;

Published:

Dec 2012

Source:

Emerg Infect Dis. 18(12):1937-1944.

Description:

During August 2011, influenza A (H3N2) variant [A(H3N2)v] virus infection developed in a child who attended an agricultural fair in Pennsylvania, USA; the virus resulted from reassortment of a swine influenza virus with influenza A(H1N1)pdm09. We int...

File Type:

[PDF - 229.52 KB]
Seasonal influenza A (H3N2) virus infections

Corporate Author:

Centers for Disease Control and Prevention (U.S.)

Published:

8/4/10

Source:

HAN ; 316

Series:

HAN ; 316

Description:

Wednesday, August 04, 2010, 19:55 EDT (7:55 PM EDT) : CDCHAN-00316-2010-08-04-ADV-N : Influenza A (H3N2) virus infections have been recently detected in people in a number of states across the U.S., including two small localized outbreaks. Sporadic c...

File Type:

[PDF - 697.06 KB]
Swine Influenza Virus A (H3N2) Infection in Human, Kansas, USA, 2009

Personal Author:

Cox, Chad M.; Neises, Daniel; Garten, Rebecca J.; Bryant, Bill; Hesse, Richard A.; Anderson, Gary A.; Trevino-Garrison, Ingrid; Shu, Bo; Lindstrom, Stephen; Klimov, Alexander I.; Finelli, Lyn;

Published:

Jun 2011

Source:

Emerg Infect Dis. 17(6):1143-1144.

File Type:

[PDF - 132.29 KB]
Retraction: Triple Reassortant Swine Influenza A (H3N2) Virus in Waterfowl

Personal Author:

Goyal, Sagar M.

Published:

Jan 2013

Source:

Emerg Infect Dis. 19(1):181.

File Type:

[PDF - 323.17 KB]