Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong

Wong, Tze-wai; Lee, Chin-kei; Tam, Wilson; Lau, Joseph Tak-fai; Yu, Tak-sun; Lui, Siu-fai; Chan, Paul K.S.; Li, Yuguo; Bresee, Joseph S.; Sung, Joseph J.Y.; Parashar, Umesh D.

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Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong

Published Date:

Feb 2004

Source:

Emerg Infect Dis. 10(2):269-276.

[PDF-251.02 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Wong, Tze-wai ; Lee, Chin-kei ; Tam, Wilson ; Lau, Joseph Tak-fai ; Yu, Tak-sun ; ... More ▼

Corporate Authors:

for the Outbreak Study Group

Description:

We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visited the index patient's ward, including 16 students with SARS and 50 healthy students. The risk of contracting SARS was sevenfold greater among students who definitely visited the index case's cubicle than in those who did not (10/27 [41%] versus 1/20 [5%], relative risk 7.4; 95% confidence interval 1.0 to 53.3). Illness rates increased directly with proximity of exposure to the index case. However, four of eight students who were in the same cubicle, but were not within 1 m of the index case-patient, contracted SARS. Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread. Transmission through fomites or small aerosols cannot be ruled out.

Subject:

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases
CDC Public Access

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