Whole-Genome Sequencing of Drug-Resistant Mycobacterium tuberculosis Strains, Tunisia, 2012–2016

Bouzouita, Imen; Cabibbe, Andrea Maurizio; Trovato, Alberto; Daroui, Henda; Ghariani, Asma; Midouni, Basma; Essalah, Leila; Mehiri, Emna; Cirillo, Daniela Maria; Saidi, Leila Slim

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Whole-Genome Sequencing of Drug-Resistant Mycobacterium tuberculosis Strains, Tunisia, 2012–2016

March 2019
By Bouzouita, Imen ; Cabibbe, Andrea Maurizio ; Trovato, Alberto ; ...
Source: Emerg Infect Dis. 25(3):547-550

[PDF-1000.36 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Bouzouita, Imen ; Cabibbe, Andrea Maurizio ; Trovato, Alberto ; Daroui, Henda ; Ghariani, Asma ; ... More +

Bouzouita, Imen ; Cabibbe, Andrea Maurizio ; Trovato, Alberto ; Daroui, Henda ; Ghariani, Asma ; Midouni, Basma ; Essalah, Leila ; Mehiri, Emna ; Cirillo, Daniela Maria ; Saidi, Leila Slim Less -
Description:

To investigate transmission of drug-resistant strains of | in Tunisia, we performed whole-genome sequencing on 46 multidrug-resistant strains isolated during 2012–2016. Core-genome multilocus sequence typing grouped 30 strains (65.2%) into 3 clusters, indicating extensive recent transmission and Haarlem clone predominance. Whole-genome sequencing might help public health services undertake appropriate control actions.
Subjects:

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Adult Drug Resistance, Multiple, Bacterial Female Genes, Bacterial Genome, Bacterial History, 21st Century Humans Male Middle Aged Mutation Mycobacterium Tuberculosis Phylogeny Public Health Surveillance Retrospective Studies Tuberculosis, Multidrug-Resistant Tuberculosis, Multidrug-Resistant/history Whole Genome Sequencing Young Adult
Source:

Emerg Infect Dis. 25(3):547-550
Pubmed Central ID:

PMC6390741
Document Type:

Journal Article
Genre:

Historical Article
Place as Subject:

Tunisia
Volume:

25
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:8d0cf975e8af640506671c8f1082765ab1bbc34cc79473a323ae05d347a09cb9
Download URL:

https://stacks.cdc.gov/view/cdc/76655/cdc_76655_DS1.pdf
File Type:

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