Whole-Genome Sequencing of Drug-Resistant Mycobacterium tuberculosis Strains, Tunisia, 2012–2016

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Bouzouita, Imen ; Cabibbe, Andrea Maurizio ; Trovato, Alberto ; Daroui, Henda ; Ghariani, Asma ; Midouni, Basma ; Essalah, Leila ; Mehiri, Emna ; Cirillo, Daniela Maria ; Saidi, Leila Slim
• Description:
  To investigate transmission of drug-resistant strains of | in Tunisia, we performed whole-genome sequencing on 46 multidrug-resistant strains isolated during 2012–2016. Core-genome multilocus sequence typing grouped 30 strains (65.2%) into 3 clusters, indicating extensive recent transmission and Haarlem clone predominance. Whole-genome sequencing might help public health services undertake appropriate control actions.
• Subjects:
  Adult Drug Resistance, Multiple, Bacterial Female Genes, Bacterial Genome, Bacterial History, 21st Century Humans Male Middle Aged Mutation Mycobacterium Tuberculosis Phylogeny Public Health Surveillance Retrospective Studies Tuberculosis, Multidrug-Resistant Tuberculosis, Multidrug-Resistant/history Whole Genome Sequencing Young Adult

  More +
• Source:
  Emerg Infect Dis. 25(3):547-550
• Pubmed Central ID:
  PMC6390741
• Document Type:
  Journal Article
• Genre:
  Historical Article
• Place as Subject:
  Tunisia
• Volume:
  25
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:8d0cf975e8af640506671c8f1082765ab1bbc34cc79473a323ae05d347a09cb9
• Download URL:
  https://stacks.cdc.gov/view/cdc/76655/cdc_76655_DS1.pdf
• File Type:
  [PDF - 1000.36 KB ]