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Alternative Title:Public Health Rep
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Description:The acquired immunodeficiency syndrome (AIDS) is a devastating new disease caused by the human immunodeficiency virus (HIV). This retrovirus causes profound immunoincompetence in its infected hosts, who are thereafter susceptible to develop myriad severe and relapsing protozoal, fungal, bacterial, viral, and arthropodal opportunistic infections, as well as unusual malignancies. The more than 50,000 patients who have developed AIDS in the United States have produced a sudden unexpected deluge of diagnostic dilemmas that are stressing laboratories of pathology everywhere. This paper describes the gross and microscopic pathology of the numerous complications in patients infected by HIV: (a) the prodromal AIDS-related complex with persistent generalized lymphadenopathy, (b) lymphoid infiltration of salivary gland and lung, including the complex of lymphoid interstitial pneumonitis-pulmonary lymphoid hyperplasia, (c) extranodal non-Hodgkin's lymphomas, (d) multifocal mucocutaneous and visceral Kaposi's sarcoma, (e) small cell undifferentiated (oat cell) carcinomas, (f) protozoal infections caused by Pneumocystis carinii, Toxoplasma gondii, Acanthamoeba, Cryptosporidium species (sp.), and Isospora belli, (g) the causes of chronic enteritis, (h) mycotic infections caused by Candida sp., Cryptococcus neoformans, Histoplasma capsulatum, Coccidioides immitis, and Sporothrix schenckii, (i) bacterial infections caused by Mycobacterium avium-intracellulare, M. tuberculosis, M. kansasii, Nocardia sp., Listeria monocytogenes, Legionella sp., Treponema pallidum, and others, (j) viral infections caused by cytomegalovirus, herpes simplex and zoster, polyomavirus (progressive multifocal leukoencephalopathy), hepatitis B, molluscum contagiosum, and papillomavirus, (k) oral hairy leukoplakia, (l) subacute encephalopathy, and (m) Norwegian scabies.
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Subjects:Acquired Immunodeficiency Syndrome AIDS-Related Complex Brain Diseases Candidiasis Cryptococcosis Cryptosporidiosis Cytomegalovirus Infections Histoplasmosis Humans Lung Lymphoma, Non-Hodgkin Mycobacterium Infections Nocardia Infections Pneumonia, Pneumocystis Polyomavirus Research Article Salivary Glands Sarcoma, Kaposi Toxoplasmosis Tumor Virus Infections
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Pubmed ID:2836878
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Pubmed Central ID:PMCnull
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Main Document Checksum:urn:sha256:a51648a5145c2f05430504e7687d9b7dd81c3ff92ba0603518f6362122b2dcc8
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Personal Author:Roper, William L. ;Winkenwerder, William05/01/1988 | Public Health Rep. 103(3):305-308Description:An estimated 40 percent of the nation's 55,000 persons with acquired immunodeficiency syndrome (AIDS) have received care under the Medicaid Program, w...Personal Author:Fauci, A S ;Fischinger, P J05/01/1988 | Public Health Rep. 103(3):230-236Description:The development of a safe and effective vaccine against infection by the human immunodeficiency virus (HIV) is of paramount importance to the preventi...Personal Author:Broder, S ;Fauci, A S05/01/1988 | Public Health Rep. 103(3):224-229Description:The discovery of effective therapies for HIV requires a fundamental knowledge of retroviral infections. Research by the Public Health Service and coll...Personal Author:Weiss, R ;Thier, S O05/01/1988 | Public Health Rep. 103(3):289-292Description:In 1985 the Institute of Medicine, National Academy of Sciences devoted its annual meeting to an exploration of acquired immunodeficiency syndrome (AI...Personal Author:McCarthy, C05/01/1988 | Public Health Rep. 103(3):273-277Description:The American Hospital Association (AHA) has taken a leadership role in assisting health care providers in dealing effectively with the challenges of A...Personal Author:Sundwall, D N ;Bailey, D05/01/1988 | Public Health Rep. 103(3):293-298Description:The Health Resources and Services Administration (HRSA), one of the seven agencies of the Public Health Service, is working to meet some of the resour...Personal Author:Mason, James O. ;Noble, Gary R....1988 May-Jun | Public Health Rep. 103(3):255-260Description:The human immunodeficiency virus (HIV) is estimated to have infected more than a million people in the United States and millions more in other countr...Personal Author:Dondero, Timothy J. ;Pappaioanou, Marguerite...1988 May-Jun | Public Health Rep. 103(3):213-220Description:A comprehensive, multifaceted approach to HIV surveillance is needed to provide the information necessary for public health management and policy. Bec...Personal Author:Kawata, P A ;Andriote, J M1988 May-Jun | Public Health Rep. 103(3):299-304Description:Because of the variety of needs engendered by AIDS, a broadbased response to the epidemic is warranted. The traditional medical model, with its emphas...Personal Author:Samuels, M E ;Mann, J...1988 May-Jun | Public Health Rep. 103(3):221-223Description:The World Health Organization (WHO) estimates that the world total of AIDS cases will reach 300,000 by the end of 1988 and 500,000 to 3 million over t...Personal Author:Petricciani, J C ;Epstein, J S1988 May-Jun | Public Health Rep. 103(3):236-241Description:Present safeguards for the blood supply consist of three tiers of protection: donor deferral based on a donor's history of risk factors, confidential ...Personal Author:Spero, J R1988 May-Jun | Public Health Rep. 103(3):278-281Description:Nursing students, as future health care providers, need comprehensive instruction about AIDS--the many manifestations of both the disease itself and t...
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