Progress In Drug Therapies For HIV Infection

Broder, S; Fauci, A S

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Progress In Drug Therapies For HIV Infection

05/01/1988
By Broder, S ; Fauci, A S
Source: Public Health Rep. 103(3):224-229

[PDF-973.22 KB]

English

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Alternative Title:

Public Health Rep
Personal Author:

Broder, S ; Fauci, A S

Broder, S ; Fauci, A S Less -
Description:

The discovery of effective therapies for HIV requires a fundamental knowledge of retroviral infections. Research by the Public Health Service and collaborating organizations on oncogenic viruses, including retroviruses, has provided much of the basic understanding of retroviruses in general and anti-retroviral therapeutic strategies in particular. Early work by the Viral Cancer and Developmental Therapeutic Programs of the National Cancer Institute and the Intramural Research Program of the National Institute of Allergy and Infectious Diseases has contributed much of the current understanding of AIDS and its therapy. This paper describes the progress that has been made in the treatment of AIDS and the programs that have been created to develop future therapies. These programs include efforts to screen existing compounds for activity against HIV, to design new anti-HIV therapies, and to test potential agents in controlled clinical trials. As a result of these activities, researchers have identified one drug, AZT, that has proven effective in prolonging the lives of some patients with AIDS, and are developing several other promising compounds. The key question no longer is whether HIV infection can be treated, but what is the best and fastest way to develop new therapies and improve existing ones.
Subjects:

[+]

Acquired Immunodeficiency Syndrome Drug Evaluation Drug Evaluation, Preclinical Humans Thymidine Zidovudine
Source:

Public Health Rep. 103(3):224-229
Pubmed ID:

3131811
Pubmed Central ID:

PMCnull
Document Type:

Journal Article
Name as Subject:

National Institutes of Health (U.S.) ; National Institutes of Health (U.S.)

National Institutes of Health (U.S.) ; National Institutes of Health (U.S.) Less -
Place as Subject:

North America
Volume:

103
Issue:

3
Collection(s):

Public Health Reports
Main Document Checksum:

[+]

urn:sha256:a0650fb29c9e979c097f72f3a337a80298e8bed1f3f6759b83b305c422ec2e07
Download URL:

https://stacks.cdc.gov/view/cdc/63159/cdc_63159_DS1.pdf
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Progress In Drug Therapies For HIV Infection

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