Comparison of 2016–17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Alarcon, Pablo ; Brouwer, Adam ; Venkatesh, Divya ; Duncan, Daisy ; Dovas, Chrysostomos I. ; Georgiades, George ; Monne, Isabella ; Fusaro, Alice ; Dan, Adam ; Śmietanka, Krzysztof ; Ragias, Vassilios ; Breed, Andrew C. ; Chassalevris, Taxiarchis ; Goujgoulova, Gabriela ; Hjulsager, Charlotte Kristiane ; Ryan, Eoin ; Sánchez, Azucena ; Niqueux, Eric ; Tammiranta, Niina ; Zohari, Siamak ; Stroud, David A. ; Savić, Vladimir ; Lewis, Nicola S. ; Brown, Ian H.
• Description:
  We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016-17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016-17 epizootic was the largest in Europe by number of countries and farms affected and greatest diversity of wild birds infected. We observed significant differences among the 3 epizootics regarding region affected, epidemic curve, seasonality, and outbreak duration, making it difficult to predict future HPAI epizootics. However, we know that in 2005-06 and 2016-17 the initial peak of wild bird detections preceded the peak of poultry outbreaks within Europe. Phylogenetic analysis of 2016-17 viruses indicates 2 main pathways into Europe. Our findings highlight the need for global surveillance of viral changes to inform disease preparedness, detection, and control.
• Subjects:
  Animals Animals, Wild Birds Disease Outbreaks Genome, Viral Geography, Medical History, 21St Century Influenza A Virus Influenza In Birds/Epidemiology Influenza In Birds/History Influenza In Birds/Virology Influenza In Birds Transmission Morbidity Mortality Phylogeny Poultry Diseases Spatio-Temporal Analysis Zoonoses

  More +
• Source:
  Emerg Infect Dis. 24(12):2270-2283
• Pubmed ID:
  30457528
• Pubmed Central ID:
  PMC6256410
• Document Type:
  Journal Article
• Funding:
  HHSN272201400008C/AI/NIAID NIH HHS/United States
• Genre:
  Historical Article
• Place as Subject:
  Europe
• Volume:
  24
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4b7b4519da5ee2f487f6cad18777eb3a051bfa4bf94ce53dc5691040411e6350
• Download URL:
  https://stacks.cdc.gov/view/cdc/61331/cdc_61331_DS1.pdf
• File Type:
  [PDF - 6.06 MB ]