Outbreak of Tuberculosis and Multidrug-Resistant Tuberculosis, Mbuji-Mayi Central Prison, Democratic Republic of the Congo

Kayomo, Michel Kaswa; Hasker, Epco; Aloni, Muriel; Nkuku, Léontine; Kazadi, Marcel; Kabengele, Thierry; Muteteke, Dorcas; Kapita, François; Lufulwabo, Alphonse; Mukadi, Ya Diul; Muyembe-Tamfum, Jean-Jacques; Ieven, Margareta; de Jong, Bouke C.; Boelaert, Marleen

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Outbreak of Tuberculosis and Multidrug-Resistant Tuberculosis, Mbuji-Mayi Central Prison, Democratic Republic of the Congo

Supporting Files Public Domain

November 2018
By Kayomo, Michel Kaswa ; Hasker, Epco ; Aloni, Muriel ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Kayomo, Michel Kaswa ; Hasker, Epco ; Aloni, Muriel ; Nkuku, Léontine ; Kazadi, Marcel ; Kabengele, Thierry ; Muteteke, Dorcas ; Kapita, François ; Lufulwabo, Alphonse ; Mukadi, Ya Diul ; Muyembe-Tamfum, Jean-Jacques ; Ieven, Margareta ; de Jong, Bouke C. ; Boelaert, Marleen
Description:

After an alert regarding ≈31 tuberculosis (TB) cases, 3 of which were rifampin-resistant TB cases, in Mbuji-Mayi Central Prison, Democratic Republic of the Congo, we conducted an outbreak investigation in January 2015. We analyzed sputum of presumptive TB patients by using the Xpert MTB/RIF assay. We also assessed the Mycobacterium tuberculosis isolates' drug-susceptibility patterns and risk factors for TB infection. Among a prison population of 918 inmates, 29 TB case-patients were already undergoing treatment. We found an additional 475 presumptive TB case-patients and confirmed TB in 170 of them. In March 2015, the prevalence rate of confirmed TB was 21.7% (199/918 inmates). We detected an additional 14 cases of rifampin-resistant TB and initiated treatment in all 14 of these case-patients. Overcrowded living conditions and poor nutrition appeared to be the driving factors behind the high TB incidence in this prison.
Subjects:

Antimicrobial Resistance Bacteria Incidence Mbuji-Mayi MDR TB Multidrug-resistant Outbreak Prisons Research TB Tuberculosis Tuberculosis And Other Mycobacteria Xpert MTB/RIF
Source:

Emerg Infect Dis. 24(11):2029-2035
Pubmed ID:

30334730
Pubmed Central ID:

PMC6199999
Document Type:

Journal Article
Place as Subject:

Democratic Republic of the Congo
Location:

Africa
Volume:

24
Issue:

11
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:41876ef082a93994ac621be78d5a7344982ccad02e40888b731cf62488da08ab
Download URL:

https://stacks.cdc.gov/view/cdc/60401/cdc_60401_DS1.pdf
File Type:

[PDF - 1.43 MB ]

File Language:

English

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