Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Cohen, Regev ; Babushkin, Frida ; Shapiro, Maurice ; Uda, Martina ; Atiya-Nasagi, Yafit ; Klein, Dar ; Finn, Talya
• Description:
  We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3-4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroconversion. Rickettsia spp. from the 2 case-patients who died were sequenced and identified as Rickettsia conorii subsp. israelensis. Purpura fulminans has been described in association with R. rickettsii and R. indica, but rarely with R. conorii subsp. israelensis.
• Subjects:
  Adult Aged Case Series CME Disease Outbreaks Fatal Outcome Female Humans Israel Israeli Spotting Fever Middle Aged Purpura Fulminans Rickettsia Rickettsia Conorii Subsp. Israelensis Sharon District Spotted Fever Group Rickettsiosis Synopsis Two Cases Of Israeli Spotted Fever With Purpura Fulminans, Sharon District, Israel Vector-borne Infections Zoonoses

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• Source:
  Emerg Infect Dis. 24(5):835-840
• Pubmed ID:
  29664383
• Pubmed Central ID:
  PMC5938761
• Document Type:
  Journal Article
• Volume:
  24
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:54d2f414b2d36f999f88a117b2ef08526e3c111610673016f04833d1c3e54f6f
• Download URL:
  https://stacks.cdc.gov/view/cdc/54042/cdc_54042_DS1.pdf
• File Type:
  [PDF - 979.51 KB ]