Details:

Alternative Title:
Cancer Causes Control
Personal Author:
Cook, Erin E. ; Gershman, Susan T. ; Kim, Jane J. ; Tamimi, Rulla M. ; Klevens, R. Monina ; ... More +
Cook, Erin E. ; Gershman, Susan T. ; Kim, Jane J. ; Tamimi, Rulla M. ; Klevens, R. Monina ; Holmes, Michelle D. Less -
Description:
Purpose

To understand trends in the incidence and mortality of two human papillomavirus (HPV)-associated cancers, cervical and oropharyngeal cancer, in Massachusetts.

Methods

From 2004–2014, the Massachusetts Cancer Registry recorded 3,996 incident cases of oropharyngeal cancer and 2,193 incident cases of cervical cancer. Mortality data were obtained from the Massachusetts Registry of Vital Records and Statistics from 2008–2014. Rates were age-standardized to the 2000 US population and trends were assessed using joinpoint regression.

Results

While the incidence rate of cervical cancer (5.46 per 100,000) decreased by 2.41% annually (p=0.004), the incidence rate of oropharyngeal cancer among males (7.85 per 100,000) increased by 2.82% annually (p=0.0002). Mortality rates for both cancers decreased from 2008–2014 but were not statistically significant (Cervical −3.73% annually, p=0.29; Oropharyngeal −1.94% annually, p=0.44).

Conclusion

The rising incidence rate of oropharyngeal cancer in men and the decreasing, but relatively high, incidence rate of cervical cancer in women highlight the need for further screening and prevention by HPV vaccination in Massachusetts.


Subjects:
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Adult Aged Aged, 80 And Over Female Humans Incidence Male Middle Aged Oropharyngeal Neoplasms Papillomaviridae Papillomavirus Infections Registries Uterine Cervical Neoplasms Young Adult
Source:
Cancer Causes Control. 29(4-5):435-443
Pubmed ID:
29497883
Pubmed Central ID:
PMC5899047
Document Type:
Journal Article
Funding:
R25 CA 98566-10/National Institutes of Health/ ; T32 ES 007069/National Institutes of Health/ ; P01 CA087969/CA/NCI NIH HHS/United States ; U58 DP000821/DP/NCCDPHP CDC HHS/United States ; T32 CA 009001/National Institutes of Health/ ; ... More +
R25 CA 98566-10/National Institutes of Health/ ; T32 ES 007069/National Institutes of Health/ ; P01 CA087969/CA/NCI NIH HHS/United States ; U58 DP000821/DP/NCCDPHP CDC HHS/United States ; T32 CA 009001/National Institutes of Health/ ; R25 CA098566/CA/NCI NIH HHS/United States ; T32 ES007069/ES/NIEHS NIH HHS/United States ; NU58DP006271-01-00/Centers for Disease Control and Prevention/ ; T32 CA009001/CA/NCI NIH HHS/United States Less -
Place as Subject:
Massachusetts
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d86dc6762562cac63616cc2a320e248be14fed9f2a369946ec2078a70b05c4fc
Download URL:
https://stacks.cdc.gov/view/cdc/53495/cdc_53495_DS1.pdf
File Type:

Supporting Files

• 	NIHMS947363-supplement-10552_2018_1016_MOESM1_ESM.docx	docx
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