Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis

Achar, Jay; Hewison, Cathy; Cavalheiro, Ana P.; Skrahina, Alena; Cajazeiro, Junia; Nargiza, Parpieva; Herboczek, Krzysztof; Rajabov, Assliddin S.; Hughes, Jennifer; Ferlazzo, Gabriella; Seddon, James A.; du Cros, Philipp

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Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis

Oct 17 2017
By Achar, Jay ; Hewison, Cathy ; Cavalheiro, Ana P. ; ...
Source: Emerg Infect Dis. 23(10):1711-1713.

[PDF-346.30 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Achar, Jay ; Hewison, Cathy ; Cavalheiro, Ana P. ; Skrahina, Alena ; Cajazeiro, Junia ; ... More +

Achar, Jay ; Hewison, Cathy ; Cavalheiro, Ana P. ; Skrahina, Alena ; Cajazeiro, Junia ; Nargiza, Parpieva ; Herboczek, Krzysztof ; Rajabov, Assliddin S. ; Hughes, Jennifer ; Ferlazzo, Gabriella ; Seddon, James A. ; du Cros, Philipp Less -
Description:

We describe 27 children and adolescents <18 years of age who received bedaquiline during treatment for multidrug-resistant tuberculosis. We report good treatment responses and no cessation attributable to adverse effects. Bedaquiline could be considered for use with this age group for multidrug-resistant tuberculosis when treatment options are limited.
Subjects:

[+]

Adolescents Antimicrobial Resistance Bacteria Bedaquiline Children Dispatch MDR TB Multidrug-resistant Tuberculosis Multidrug Resistance Mycobacterium Tuberculosis Off-label Use Pediatric Respiratory Infections Treatment Tuberculosis XDR TB
Source:

Emerg Infect Dis. 23(10):1711-1713.
Pubmed ID:

28758889
Pubmed Central ID:

PMC5621552
Document Type:

Journal Article
Place as Subject:

United Kingdom ; France ; Tajikistan ; Belarus ; Uzbekistan ; ... More +

United Kingdom ; France ; Tajikistan ; Belarus ; Uzbekistan ; South Africa Less -
Location:

Europe ; Asia ; Africa

Europe ; Asia ; Africa Less -
Volume:

23
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:301a76b26a3e6564c329d3e918d9c2bb9e6abbed78597649108805b58db745ce
Download URL:

https://stacks.cdc.gov/view/cdc/48982/cdc_48982_DS1.pdf
File Type:

17-0303.nxml

xml

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