Welcome to CDC stacks | Two-Year Impact of Prevention Programs on Adolescent Depression: An Integrative Data Analysis Approach - 46438 | CDC Public Access
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
Clear All Simple Search
Advanced Search
Two-Year Impact of Prevention Programs on Adolescent Depression: An Integrative Data Analysis Approach
  • Published Date:
    Feb 2018
  • Source:
    Prev Sci. 19(Suppl 1):74-94.

Public Access Version Available on: February 01, 2019 information icon
Please check back on the date listed above.
  • Pubmed ID:
  • Pubmed Central ID:
  • Description:
    This paper presents the first findings of an integrative data analysis of individual-level data from 19 adolescent depression prevention trials (n = 5210) involving nine distinct interventions across 2 years post-randomization. In separate papers, several interventions have been found to decrease the risk of depressive disorders or elevated depressive/internalizing symptoms among youth. One type of intervention specifically targets youth without a depressive disorder who are at risk due to elevated depressive symptoms and/or having a parent with a depressive disorder. A second type of intervention targets two broad domains: prevention of problem behaviors, which we define as drug use/abuse, sexual risk behaviors, conduct disorder, or other externalizing problems, and general mental health. Most of these latter interventions improve parenting or family factors. We examined the shared and unique effects of these interventions by level of baseline youth depressive symptoms, sociodemographic characteristics of the youth (age, sex, parent education, and family income), type of intervention, and mode of intervention delivery to the youth, parent(s), or both. We harmonized eight different measures of depression utilized across these trials and used growth models to evaluate intervention impact over 2 years. We found a significant overall effect of these interventions on reducing depressive symptoms over 2 years and a stronger impact among those interventions that targeted depression specifically rather than problem behaviors or general mental health, especially when baseline symptoms were high. Implications for improving population-level impact are discussed.

  • Document Type:
  • Collection(s):
  • Funding:
    MH071320/National Institute of Mental Health/
    MH48696/National Institute of Mental Health/
    MH064735/National Institute of Mental Health/
    MH064503/National Institute of Mental Health/
    MH52270/National Institute of Mental Health/
    961730/William T. Grant Foundation/
    DA07031/National Institute on Drug Abuse/
    DA13773/National Institute on Drug Abuse/
    MH61143/National Institute of Mental Health/
    DA017462/National Institute on Drug Abuse/
    DA025894/National Institute on Drug Abuse/
    U01PS000671/Centers for Disease Control and Prevention/
    DA018374/National Institute on Drug Abuse/
    MH068685/National Institute of Mental Health/
    DA007029/National Institute on Drug Abuse/
    MH048118/National Institute of Mental Health/
    MH072918/National Institute of Mental Health/
    MH64707/National Institute of Mental Health/
    R01 DA018374/DA/NIDA NIH HHS/United States
    R01 MH052270/MH/NIMH NIH HHS/United States
    R01 MH064735/MH/NIMH NIH HHS/United States
    R01 DA007031/DA/NIDA NIH HHS/United States
    P30 MH039246/MH/NIMH NIH HHS/United States
    R01 MH049155/MH/NIMH NIH HHS/United States
    R01 MH040859/MH/NIMH NIH HHS/United States
    R01 DA026874/DA/NIDA NIH HHS/United States
    R37 DA007031/DA/NIDA NIH HHS/United States
    K23 MH071320/MH/NIMH NIH HHS/United States
    R01 DA017462/DA/NIDA NIH HHS/United States
    R01 DA025894/DA/NIDA NIH HHS/United States
    R01 MH064503/MH/NIMH NIH HHS/United States
    R01 MH064717/MH/NIMH NIH HHS/United States
    K08 MH072918/MH/NIMH NIH HHS/United States
    P30 MH068685/MH/NIMH NIH HHS/United States
    R01 MH064707/MH/NIMH NIH HHS/United States
    U01 PS000671/PS/NCHHSTP CDC HHS/United States
  • Supporting Files:
    No Additional Files
No Related Documents.
You May Also Like: