Phenopedia and Genopedia: disease-centered and gene-centered views of the evolving knowledge of human genetic associations

Yu, W.; Clyne, M.; Khoury, M. J.; Gwinn, M.

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Phenopedia and Genopedia: disease-centered and gene-centered views of the evolving knowledge of human genetic associations

Published Date:

Oct 27 2009

Source:

Bioinformatics. 2009; 26(1):145-146.

[PDF-75.81 KB]

Details:

Personal Authors:

Yu, W. ; Clyne, M. ; Khoury, M. J. ; Gwinn, M. ;

Keywords:

[+]

Description:

We developed web-based applications that encourage the exploration of the literature on human genetic associations by using a database that is continuously updated from PubMed. These applications provide user-friendly interfaces for searching summarized information on human genetic associations, using either genes or diseases as the starting point.|Phenopedia and Genopedia can be freely accessed at http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do and http://www.hugenavigator.net/HuGENavigator/startPagePedia.do, respectively.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Supporting Files:

	btp618.nxml	text/plain
	btp618_bioinf-2009-1349-File001.doc	application/msword
	btp618_index.html	text/html
	license.txt	text/plain

No Related Documents.

You May Also Like:

Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases

Personal Author:

Khoury, Muin J.; Bertram, Lars; Boffetta, Paolo; Butterworth, Adam S.; Chanock, Stephen J.; Dolan, Siobhan M.; Fortier, Isabel; Garcia-Closas, Montserrat; Gwinn, Marta; Higgins, Julian P. T.; Janssens, A. Cecile J. W.; Ostell, James; Owen, Ryan P.; Pagon, Roberta A.; Rebbeck, Timothy R.; Rothman, Nathaniel; Bernstein, Jonine L.; Burton, Paul R.; Campbell, Harry; Chockalingam, Anand; Furberg, Helena; Little, Julian; O'Brien, Thomas R.; Seminara, Daniela; Vineis, Paolo; Winn, Deborah M.; Yu, Wei; Ioannidis, John P. A.;

Published:

Jun 04 2009

Source:

Am J Epidemiol. 2009; 170(3):269-279.

Description:

Genome-wide association studies (GWAS) have led to a rapid increase in available data on common genetic variants and phenotypes and numerous discoveries of new loci associated with susceptibility to common complex diseases. Integrating the evidence f...

File Type:

[PDF - 211.90 KB]
Gene Prospector: An evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseases

Personal Author:

Yu, Wei; Wulf, Anja; Liu, Tiebin; Khoury, Muin J; Gwinn, Marta;

Published:

Dec 08 2008

Source:

BMC Bioinformatics. 2008; 9:528.

Description:

Background : Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology. Genetic association studies, such as recent genome-wide association ...

File Type:

[PDF - 367.16 KB]
Knowledge integration at the center of genomic medicine

Personal Author:

Khoury, Muin J.; Gwinn, Marta; Dotson, W. David; Schully, Sheri D.;

Published:

Jul 2012

Source:

Genet Med. 14(7):643-647.

Description:

Three articles in this issue of Genetics in Medicine describe examples of "knowledge integration," involving methods for generating and synthesizing rapidly emerging information on health-related genomic technologies and engaging stakeholde...

File Type:

[PDF - 133.97 KB]
Use of genomic panels to determine risk of developing type 2 diabetes in the general population: a targeted evidence-based review

Personal Author:

Palomaki, Glenn E.; Melillo, Stephanie; Marrone, Michael; Douglas, Michael P.;

Published:

Mar 14 2013

Source:

Genet Med. 15(8):600-611.

Description:

This evidence review addresses whether type 2 diabetes genomic risk panels improve health outcomes (e.g., reduce rates of developing type 2 diabetes) in low- or high-risk adults; two clinical scenarios promulgated by commercial companies offering suc...

File Type:

[PDF - 418.17 KB]
An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiology

Personal Author:

Yu, Wei; Yesupriya, Ajay; Wulf, Anja; Qu, Junfeng; Khoury, Muin J; Gwinn, Marta;

Published:

Nov 09 2007

Source:

BMC Bioinformatics. 2007; 8:436.

Description:

Background : Identifying relevant research in an ever-growing body of published literature is becoming increasingly difficult. Establishing domain-specific knowledge bases may be a more effective and efficient way to manage and query information with...

File Type:

[PDF - 813.97 KB]