Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Pieniazek, Danua. ; Baggs, James. ; Hu, Dale J. ; Matar, Ghassan M. ; Abdelnoor, Alexander M. ; ... More +
Pieniazek, Danua. ; Baggs, James. ; Hu, Dale J. ; Matar, Ghassan M. ; Abdelnoor, Alexander M. ; Mokhbat, Jacques E. ; Uwaydah, Marwan. ; Bizri, Abdul Rahman. ; Ramos, Artur. ; Janini, Luiz M. ; Tanuri, Amilcar. ; Fridlund, Carol. ; Schable, Charles. ; Heyndrickx, Leo. ; Rayfield, Mark A. ; Heneine, Walid. Less -
Description:
HIV genetic variability, phylogenetic relationships, and transmission dynamics were analyzed in 26 HIV-infected patients from Lebanon. Twenty-five specimens were identified as HIV-1 and one as HIV-2 subtype B. The 25 strains were classified into six env-C2-V3 HIV-1 subtypes: B (n = 10), A (n = 11), C (n = 1), D (n = 1), G (n = 1), and unclassifiable. Potential recombinants combining parts of viral regions from different subtypes Aenv/Dpol/Agag, Genv/Apol, and the unclassifiable-subtype(env)/unclassifiable-subtype(pol)/Agag were found in three patients. Epidemiologic analysis of travel histories and behavioral risks indicated that HIV-1 and HIV-2 subtypes reflected HIV strains prevalent in countries visited by patients or their sex partners. Spread of complex HIV-subtype distribution patterns to regions where HIV is not endemic may be more common than previously thought. Blood screening for both HIV-1 and HIV-2 in Lebanon is recommended to protect the blood supply. HIV subtype data provide information for vaccine development.
Subjects:
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Adult Base Sequence DNA, Viral Female Hiv-1 Hiv-2 Hiv Core Protein P24 Hiv Envelope Protein Gp120 Hiv Infections Hiv Protease Humans Male Middle Aged Molecular Sequence Data
Source:
Emerg Infect Dis. 4(4):649-656.
Document Type:
Journal Article
Place as Subject:
Lebanon
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:11ef4ecabb4049fada4da0cccea1b7a646557e7f018e7e3479663c7fd45822ac
Download URL:
https://stacks.cdc.gov/view/cdc/3750/cdc_3750_DS1.pdf
File Type:

Supporting Files

• 	9866744.nxml	txt
  	license.txt	txt

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