Effectiveness of pneumococcal polysaccharide vaccine for preschool-age children with chronic disease.
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Published Date:1999 Nov-Dec
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Source:Emerg Infect Dis. 5(6):828-831.
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Description:To estimate the effectiveness of pneumococcal polysaccharide vaccine, we serotyped isolates submitted to the Pneumococcal Sentinel Surveillance System from 1984 to 1996 from 48 vaccinated and 125 unvaccinated children 2 to 5 years of age. Effectiveness against invasive disease caused by serotypes included in the vaccine was 63%. Effectiveness against serotypes in the polysaccharide vaccine but not in a proposed seven-valent protein conjugate vaccine was 94%.
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