Temporally Associated Invasive Pneumococcal Disease and SARS-CoV-2 Infection, Alaska, USA, 2020–2021

Newell, Katherine; Fischer, Marc; Massey, Stephanie; Orell, Laurie; Steinberg, Jonathan; Tompkins, Megan; Castrodale, Louisa; McLaughlin, Joseph

doi:10.3201/eid2909.230080

i

Temporally Associated Invasive Pneumococcal Disease and SARS-CoV-2 Infection, Alaska, USA, 2020–2021

Supporting Files Public Domain

9 2023
By Newell, Katherine ; Fischer, Marc ; Massey, Stephanie ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Newell, Katherine ; Fischer, Marc ; Massey, Stephanie ; Orell, Laurie ; Steinberg, Jonathan ; Tompkins, Megan ; Castrodale, Louisa ; McLaughlin, Joseph
Description:

Streptococcus pneumoniae can co-infect persons who have viral respiratory tract infections. However, research on S. pneumoniae infections that are temporally associated with SARS-CoV-2 infections is limited. We described the epidemiology and clinical course of patients who had invasive pneumococcal disease (IPD) and temporally associated SARS-CoV-2 infections in Alaska, USA, during January 1, 2020-December 23, 2021. Of 271 patients who had laboratory-confirmed IPD, 55 (20%) had a positive SARS-CoV-2 test result. We observed no major differences in age, race, sex, or underlying medical conditions among IPD patients with and without SARS-CoV-2. However, a larger proportion of IPD patients with SARS-CoV-2 died (16%, n = 9) than for those with IPD alone (4%, n = 9) (p<0.01). IPD patients with SARS-CoV-2 were also more likely to be experiencing homelessness (adjusted OR 3.5; 95% CI 1.7-7.5). Our study highlights the risk for dual infection and ongoing benefits of pneumococcal and COVID-19 vaccination, especially among vulnerable populations.
Subjects:

COVID-19 COVID-19 Vaccines Humans Pneumococcal Infections Pneumococcal Vaccines SARS-CoV-2 Streptococcus Pneumoniae
Keywords:

Alaska Bacteria Co-infection Invasive Pneumococcal Disease IPD Pneumococcal Infections Respiratory Infections Temporally Associated United States Zoonoses
Source:

Emerg Infect Dis. 2023; 29(9):1765-1771
Pubmed ID:

37506683
Pubmed Central ID:

PMC10461657
Document Type:

Journal Article
Place as Subject:

Alaska
Volume:

29
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:45ba9b50f0e1a6018467d164e8a62bc5a9322cddaed38e6a0bbc25f7bdcf6e71
Download URL:

https://stacks.cdc.gov/view/cdc/133571/cdc_133571_DS1.pdf
File Type:

[PDF - 910.11 KB ]

File Language:

English

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