Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs

de Wit, Emmie; Marzi, Andrea; Bushmaker, Trenton; Brining, Doug; Scott, Dana; Richt, Juergen A.; Geisbert, Thomas W.; Feldmann, Heinz

doi:10.3201/eid2104.142012

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Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs

Published Date:

Apr 2015

Publisher's site:

http://dx.doi.org/10.3201/eid2104.142012 New Site Icon

Source:

Emerg Infect Dis. 21(4):702-704.

[PDF - 562.49 KB]

Details:

Personal Authors:

de Wit, Emmie ; Marzi, Andrea ; Bushmaker, Trenton ; Brining, Doug ; Scott, Dana ; ... More ▼

Keywords:

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Description:

The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs. Inoculation did not cause disease and vaccine virus shedding was minimal, which indicated that the vaccine virus does not pose a risk of dissemination in pigs.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

14-2012.nxml	text/plain
license.txt	text/plain

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