Pathogenicity of 2 Porcine Deltacoronavirus Strains in Gnotobiotic Pigs

Jung, Kwonil; Hu, Hui; Eyerly, Bryan; Lu, Zhongyan; Chepngeno, Juliet; Saif, Linda J.

doi:10.3201/eid2104.141859

i

Pathogenicity of 2 Porcine Deltacoronavirus Strains in Gnotobiotic Pigs

Supporting Files Public Domain

Apr 2015
By Jung, Kwonil ; Hu, Hui ; Eyerly, Bryan ; ...

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Alternative Title:

Emerg Infect Dis
Personal Author:

Jung, Kwonil ; Hu, Hui ; Eyerly, Bryan ; Lu, Zhongyan ; Chepngeno, Juliet ; Saif, Linda J.
Description:

To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21-120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.
Subjects:

Coronavirus Dispatch Gnotobiotic Pigs Pathogenicity Pathogenicity Of 2 Porcine Deltacoronavirus Strains In Gnotobiotic Pigs PCR PDCoV Pigs Porcine Deltacoronavirus Strain OH-FD22 Strain OH-FD100 Strains Viruses
Source:

Emerg Infect Dis. 21(4):650-654.
Document Type:

Journal Article
Volume:

21
Issue:

4
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:ca07330c661b9df9f47359cce5365d7ee5c19501aa788ee9cf9bd4370c040ebf
Download URL:

https://stacks.cdc.gov/view/cdc/29337/cdc_29337_DS1.pdf
File Type:

[PDF - 2.88 MB ]

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